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The map label for this gene is yihV [H]

Identifier: 197118860

GI number: 197118860

Start: 2876513

End: 2877421

Strand: Reverse

Name: yihV [H]

Synonym: Gbem_2483

Alternate gene names: 197118860

Gene position: 2877421-2876513 (Counterclockwise)

Preceding gene: 197118861

Following gene: 197118847

Centisome position: 62.35

GC content: 64.69

Gene sequence:

>909_bases
ATGCGATTTGACGTCGTGGGGCTCGGAGTATCTACTGTCGATCTCATCTTCACCGTGGATCAACTCCCCGGCAGCGAGAT
GGTGCAAAGGGCGGGAGAGTGCGTGATAGCGGGAGGCGGACCGGTAGCGACCGCGATGGTGACACTGGCGAGGCTGGGCG
CCGCCACTGCCATGCTGGACAGCATCGGGAGCGACTTCTTCGGGAGCTTCATACGGAGTGAATTCGCCGCCGAGGGGGTA
GATACCGGCGGGCTGGTCGTAGCCCCGGGACGGACCAGTTCTAAGGCATCGATACTGGTGCGAAAGGAGGACGGCGCCCG
CGCCATAACCTTCTCCCCCGGCGACGCACCCGAGCTTACCCCCGGCGGCGTCCGGGCCGACATCATCCGTGCCTCCAAAA
TACTGCACCTGAACGGCCGTCATTGGGACGCCTGCCTCCACGCCGCAAGGCTCGCCAAGGAAGCAGGCGTTTTGGTTTCC
TTCGACGGCGGTGCCCACCGCTACGACCCTCAACACCGCAGCATCCTTCCACAAGTAGACATCTGCATCGCAGCCCACAA
CTACGCCGCTGCCTTTGCCGGCACCGAAGACGTTGCCCAGGCGGCTAAAGCCCTTCTCGAAGCAGGCCCGCGCATCGTCG
TCGTCACGCAGGGGGCGGCGGGGAGCCGGGTATTCTCGCATGAGGGGGAAGCCTTTCACCAGCAGGCATACCGGGTGGAC
CGTGTGGTAGACACCACAGGAGCGGGTGACGCCTATCACGGCGCCTTTCTCTACGGCCTTGCCCGCGGGTTTGCGCTGGA
AGAGTCGGCAAGGTTTGCCAGCGCCGTTGCCGCCCTCAACACGCGCGCGCTCGGCGGACGGGCCGCGCTTCCCACGCTTG
TCGAAGTAGAGACGATGCTGCAGCAGTAA

Upstream 100 bases:

>100_bases
CACCCTTGCCGACGTTTTGGAGAAGATCGACACCGCCGAGCAGGGGCAGCGCGGCGTACTGGACTTCTGCATCTGATCCC
CCGGCGGAGGTTGGCGGCAC

Downstream 100 bases:

>100_bases
CCTTTCTGAATCGGCCGCCCCCACGCTGTCCTCGACCAACGCTCCGCCAGATCTCCCCCTCCCGCCAGGGAGGGGGGACT
TTTCGGCGACTGCAACATCC

Product: PfkB family carbohydrate kinase

Products: ADP; D-ribose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRFDVVGLGVSTVDLIFTVDQLPGSEMVQRAGECVIAGGGPVATAMVTLARLGAATAMLDSIGSDFFGSFIRSEFAAEGV
DTGGLVVAPGRTSSKASILVRKEDGARAITFSPGDAPELTPGGVRADIIRASKILHLNGRHWDACLHAARLAKEAGVLVS
FDGGAHRYDPQHRSILPQVDICIAAHNYAAAFAGTEDVAQAAKALLEAGPRIVVVTQGAAGSRVFSHEGEAFHQQAYRVD
RVVDTTGAGDAYHGAFLYGLARGFALEESARFASAVAALNTRALGGRAALPTLVEVETMLQQ

Sequences:

>Translated_302_residues
MRFDVVGLGVSTVDLIFTVDQLPGSEMVQRAGECVIAGGGPVATAMVTLARLGAATAMLDSIGSDFFGSFIRSEFAAEGV
DTGGLVVAPGRTSSKASILVRKEDGARAITFSPGDAPELTPGGVRADIIRASKILHLNGRHWDACLHAARLAKEAGVLVS
FDGGAHRYDPQHRSILPQVDICIAAHNYAAAFAGTEDVAQAAKALLEAGPRIVVVTQGAAGSRVFSHEGEAFHQQAYRVD
RVVDTTGAGDAYHGAFLYGLARGFALEESARFASAVAALNTRALGGRAALPTLVEVETMLQQ
>Mature_302_residues
MRFDVVGLGVSTVDLIFTVDQLPGSEMVQRAGECVIAGGGPVATAMVTLARLGAATAMLDSIGSDFFGSFIRSEFAAEGV
DTGGLVVAPGRTSSKASILVRKEDGARAITFSPGDAPELTPGGVRADIIRASKILHLNGRHWDACLHAARLAKEAGVLVS
FDGGAHRYDPQHRSILPQVDICIAAHNYAAAFAGTEDVAQAAKALLEAGPRIVVVTQGAAGSRVFSHEGEAFHQQAYRVD
RVVDTTGAGDAYHGAFLYGLARGFALEESARFASAVAALNTRALGGRAALPTLVEVETMLQQ

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=28.3783783783784, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5670342, Length=290, Percent_Identity=21.0344827586207, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4557693, Length=290, Percent_Identity=21.0344827586207, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082343, Length=306, Percent_Identity=34.3137254901961, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=29.2763157894737, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081971, Length=324, Percent_Identity=27.1604938271605, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17532905, Length=308, Percent_Identity=28.8961038961039, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322565, Length=281, Percent_Identity=25.9786476868327, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: 2.7.1.15

Molecular weight: Translated: 31428; Mature: 31428

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDVVGLGVSTVDLIFTVDQLPGSEMVQRAGECVIAGGGPVATAMVTLARLGAATAMLD
CCEEEEECCHHHEEEEEEECCCCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
SIGSDFFGSFIRSEFAAEGVDTGGLVVAPGRTSSKASILVRKEDGARAITFSPGDAPELT
HHCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCC
PGGVRADIIRASKILHLNGRHWDACLHAARLAKEAGVLVSFDGGAHRYDPQHRSILPQVD
CCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHCCCCCEE
ICIAAHNYAAAFAGTEDVAQAAKALLEAGPRIVVVTQGAAGSRVFSHEGEAFHQQAYRVD
EEEEECCHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHH
RVVDTTGAGDAYHGAFLYGLARGFALEESARFASAVAALNTRALGGRAALPTLVEVETML
HHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
QQ
CC
>Mature Secondary Structure
MRFDVVGLGVSTVDLIFTVDQLPGSEMVQRAGECVIAGGGPVATAMVTLARLGAATAMLD
CCEEEEECCHHHEEEEEEECCCCCHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
SIGSDFFGSFIRSEFAAEGVDTGGLVVAPGRTSSKASILVRKEDGARAITFSPGDAPELT
HHCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCC
PGGVRADIIRASKILHLNGRHWDACLHAARLAKEAGVLVSFDGGAHRYDPQHRSILPQVD
CCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHCCCCCEE
ICIAAHNYAAAFAGTEDVAQAAKALLEAGPRIVVVTQGAAGSRVFSHEGEAFHQQAYRVD
EEEEECCHHHHHCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHH
RVVDTTGAGDAYHGAFLYGLARGFALEESARFASAVAALNTRALGGRAALPTLVEVETML
HHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
QQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-ribose

Specific reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]