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The map label for this gene is mreC [H]

Identifier: 197118839

GI number: 197118839

Start: 2851678

End: 2852502

Strand: Reverse

Name: mreC [H]

Synonym: Gbem_2462

Alternate gene names: 197118839

Gene position: 2852502-2851678 (Counterclockwise)

Preceding gene: 197118840

Following gene: 197118838

Centisome position: 61.81

GC content: 62.67

Gene sequence:

>825_bases
ATGAAAAACTTTCTAATCCGCTATAAGCGCTTACTGCTGACCGCCGGTGTCCTTCTGGTGGCCTTCCTCACCTATGCGCT
TAACCTCAGGAACAAGGAGCATGCGAACCCCGTGGAGCGCGCCGTGATGACGCTCACCGCTCCGATTGCGGGCTCAGCCG
CCTTCCTCAGCGGCTCCGTTGGGGATGTCTGGAACAACTACGTCGATCTCATCGAGGTCAGGCGCGAGAACATCGAACTC
AGAAGAAGCGTAAAGCGCCTGAACGAGCGGATCGTCGCCAACCACGAGGCGGTCGTGGAAAACCAGAGGCTCAAGGCCCT
GCTCGAACTGAAAGGGAGCGTCGCCATCCCCTCCATCGCCGTCTCGGTGATCGGGGAGGACAGCTCCGCCTGGTTCAAGA
CGCTGGTGGTCGACCGCGGCAGCAACGACGGACTGGTTGAGGGTATGCCGGTGGTTGCGGTCGGCGGCGTGGTAGGGAGG
GTGATCAAGGTGGCTCCGCAAAGCTCCCGGGTGCTGCTTTTAACCGACCATGCCAGCGCCATCGCCGCCATCGTGCAGCG
CTCCCGGGCCCGCGGGGTGGTGCGCGGCGCCGGTGGCGGGCGCTGCTCGCTGGAGTTCACGGTCAAGGACGAGGACGTGA
AGGTCGGCGACAGCGTGATCAGCTCCGGCATCGGCGGCGTCTTTCCCAAGGGGCTTCCCATCGGGGAGGTGACCATGGTG
AAAAAAGGGGAGTACGGCGTCTTCCAGACCATTGAGGTCCGTCCCACGGTCAACATCGGCAAGCTAGAGGAGATGCTGGT
GCTGGTCCGGCAGCAACAACAATAG

Upstream 100 bases:

>100_bases
GCCGGCTCGCCTTACCAGATCGACTAGCGGTGTCGCTGCCCGTTGTTTTTTGATCGCACAGATAGGGGGCCGCAGTGCCC
CCTAAACCATTTTGAGGCCG

Downstream 100 bases:

>100_bases
TGTCCATCACAAGCGAGTCACAGCTTTGATTGCTTATCTGAAAATAACGGGAATCGTTCTCGCCGCCTGCCTGCTCCAGA
TGACGCTTCTCCCCAGGTAC

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKNFLIRYKRLLLTAGVLLVAFLTYALNLRNKEHANPVERAVMTLTAPIAGSAAFLSGSVGDVWNNYVDLIEVRRENIEL
RRSVKRLNERIVANHEAVVENQRLKALLELKGSVAIPSIAVSVIGEDSSAWFKTLVVDRGSNDGLVEGMPVVAVGGVVGR
VIKVAPQSSRVLLLTDHASAIAAIVQRSRARGVVRGAGGGRCSLEFTVKDEDVKVGDSVISSGIGGVFPKGLPIGEVTMV
KKGEYGVFQTIEVRPTVNIGKLEEMLVLVRQQQQ

Sequences:

>Translated_274_residues
MKNFLIRYKRLLLTAGVLLVAFLTYALNLRNKEHANPVERAVMTLTAPIAGSAAFLSGSVGDVWNNYVDLIEVRRENIEL
RRSVKRLNERIVANHEAVVENQRLKALLELKGSVAIPSIAVSVIGEDSSAWFKTLVVDRGSNDGLVEGMPVVAVGGVVGR
VIKVAPQSSRVLLLTDHASAIAAIVQRSRARGVVRGAGGGRCSLEFTVKDEDVKVGDSVISSGIGGVFPKGLPIGEVTMV
KKGEYGVFQTIEVRPTVNIGKLEEMLVLVRQQQQ
>Mature_274_residues
MKNFLIRYKRLLLTAGVLLVAFLTYALNLRNKEHANPVERAVMTLTAPIAGSAAFLSGSVGDVWNNYVDLIEVRRENIEL
RRSVKRLNERIVANHEAVVENQRLKALLELKGSVAIPSIAVSVIGEDSSAWFKTLVVDRGSNDGLVEGMPVVAVGGVVGR
VIKVAPQSSRVLLLTDHASAIAAIVQRSRARGVVRGAGGGRCSLEFTVKDEDVKVGDSVISSGIGGVFPKGLPIGEVTMV
KKGEYGVFQTIEVRPTVNIGKLEEMLVLVRQQQQ

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=185, Percent_Identity=34.0540540540541, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 29590; Mature: 29590

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFLIRYKRLLLTAGVLLVAFLTYALNLRNKEHANPVERAVMTLTAPIAGSAAFLSGSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCH
GDVWNNYVDLIEVRRENIELRRSVKRLNERIVANHEAVVENQRLKALLELKGSVAIPSIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEE
VSVIGEDSSAWFKTLVVDRGSNDGLVEGMPVVAVGGVVGRVIKVAPQSSRVLLLTDHASA
EEEECCCCHHHEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCEEEEEECCHHH
IAAIVQRSRARGVVRGAGGGRCSLEFTVKDEDVKVGDSVISSGIGGVFPKGLPIGEVTMV
HHHHHHHHHHCCEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEE
KKGEYGVFQTIEVRPTVNIGKLEEMLVLVRQQQQ
ECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNFLIRYKRLLLTAGVLLVAFLTYALNLRNKEHANPVERAVMTLTAPIAGSAAFLSGSV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCH
GDVWNNYVDLIEVRRENIELRRSVKRLNERIVANHEAVVENQRLKALLELKGSVAIPSIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEE
VSVIGEDSSAWFKTLVVDRGSNDGLVEGMPVVAVGGVVGRVIKVAPQSSRVLLLTDHASA
EEEECCCCHHHEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCEEEEEECCHHH
IAAIVQRSRARGVVRGAGGGRCSLEFTVKDEDVKVGDSVISSGIGGVFPKGLPIGEVTMV
HHHHHHHHHHCCEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEE
KKGEYGVFQTIEVRPTVNIGKLEEMLVLVRQQQQ
ECCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]