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The map label for this gene is pyrK [H]

Identifier: 197118779

GI number: 197118779

Start: 2779875

End: 2780684

Strand: Reverse

Name: pyrK [H]

Synonym: Gbem_2400

Alternate gene names: 197118779

Gene position: 2780684-2779875 (Counterclockwise)

Preceding gene: 197118780

Following gene: 197118778

Centisome position: 60.25

GC content: 64.32

Gene sequence:

>810_bases
ATGCAGTTTAAATCGATGGTAGTGTCGAACGTAGAGCTGTCGCCGAACTACTTCCGGATGAGGATGACCGCTCCGCAGGA
ATTGCTCGCTTCGGCGCCGGGGCAGTTTCTCATGCTCAAGGTGACCGATGCCATAGACCCGCTGCTCAGGCGCCCCTTCG
GGCTTTTCGACGTCGGGACCTTCACCGCCGAGTACGCCGGGTGCGGCACGCAGGCGTACTGCGAGATCCTGTACAAGGTG
GTGGGGAAGGGGACCAAGCTCCTCTCCGCGTTGCACCACGGCGACGTGGTGGACCTTTTGGCGCCCTTGGGCCGAGGGTT
CGACCTGGGTCCCGCTGGCGAGGAAAAGGTGCTGGTAGGCGGCGGCGTAGGCCTTGCCCCCCTTTACTACCTCGCCAAGG
CGCTGGTGGCGCGAGGCGAGAAGGTGCGCCTTTTCGCCGGCGGCAGGAACCGCGACGACATCCTCTGCATCACCGAGTTC
GAGAGGCTCGGAGTCGAGACCTACGTGGCGACCGACGACGGCACTCTGGGCGAGAGCGGCTTCGTGACCCAGGTGCTGGA
GAGGCACCTGAATAAAGGGATGCGCATCTTCGCCTGCGGCCCGACCCCGATGCTCGGCGCCGTCGCCAAGATGGCGGCTT
TGCACGAGGTCCCCTGCCAGGTCTCGATGGAGGCGTACATGGCCTGCGGCGTGGGCGCCTGCCTTGGCTGCGTAATGAAG
GGGGCCAACCACACCGAGGATACCCCCGACTACCGCTGTGTCTGCAAGGACGGCCCCGTCTTCGACAGCTTCGAACTGCA
ATGGAGTTAA

Upstream 100 bases:

>100_bases
TTCGGGTTCAGGGAATCGGGGCGCCGCAAGAACTATTACGACAATGGCGAAGACGCCATCTTGATGGAGATGCCGGTCTG
CCGGCAGTCAGAGGAGAATC

Downstream 100 bases:

>100_bases
ACATGCAAAGACCTGACATGTCCGTGGCTGTCGCCGGGATCAAGATGCGCAACCCCGTGATGACCGCATCCGGCACCTTC
GGATACGGCGCCGAGTTCGC

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MQFKSMVVSNVELSPNYFRMRMTAPQELLASAPGQFLMLKVTDAIDPLLRRPFGLFDVGTFTAEYAGCGTQAYCEILYKV
VGKGTKLLSALHHGDVVDLLAPLGRGFDLGPAGEEKVLVGGGVGLAPLYYLAKALVARGEKVRLFAGGRNRDDILCITEF
ERLGVETYVATDDGTLGESGFVTQVLERHLNKGMRIFACGPTPMLGAVAKMAALHEVPCQVSMEAYMACGVGACLGCVMK
GANHTEDTPDYRCVCKDGPVFDSFELQWS

Sequences:

>Translated_269_residues
MQFKSMVVSNVELSPNYFRMRMTAPQELLASAPGQFLMLKVTDAIDPLLRRPFGLFDVGTFTAEYAGCGTQAYCEILYKV
VGKGTKLLSALHHGDVVDLLAPLGRGFDLGPAGEEKVLVGGGVGLAPLYYLAKALVARGEKVRLFAGGRNRDDILCITEF
ERLGVETYVATDDGTLGESGFVTQVLERHLNKGMRIFACGPTPMLGAVAKMAALHEVPCQVSMEAYMACGVGACLGCVMK
GANHTEDTPDYRCVCKDGPVFDSFELQWS
>Mature_269_residues
MQFKSMVVSNVELSPNYFRMRMTAPQELLASAPGQFLMLKVTDAIDPLLRRPFGLFDVGTFTAEYAGCGTQAYCEILYKV
VGKGTKLLSALHHGDVVDLLAPLGRGFDLGPAGEEKVLVGGGVGLAPLYYLAKALVARGEKVRLFAGGRNRDDILCITEF
ERLGVETYVATDDGTLGESGFVTQVLERHLNKGMRIFACGPTPMLGAVAKMAALHEVPCQVSMEAYMACGVGACLGCVMK
GANHTEDTPDYRCVCKDGPVFDSFELQWS

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 29019; Mature: 29019

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFKSMVVSNVELSPNYFRMRMTAPQELLASAPGQFLMLKVTDAIDPLLRRPFGLFDVGT
CCCHHHHHCCEEECCCEEEEEECCHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCEEHHH
FTAEYAGCGTQAYCEILYKVVGKGTKLLSALHHGDVVDLLAPLGRGFDLGPAGEEKVLVG
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEE
GGVGLAPLYYLAKALVARGEKVRLFAGGRNRDDILCITEFERLGVETYVATDDGTLGESG
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHHCCCEEEEECCCCCCCCCH
FVTQVLERHLNKGMRIFACGPTPMLGAVAKMAALHEVPCQVSMEAYMACGVGACLGCVMK
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GANHTEDTPDYRCVCKDGPVFDSFELQWS
CCCCCCCCCCEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MQFKSMVVSNVELSPNYFRMRMTAPQELLASAPGQFLMLKVTDAIDPLLRRPFGLFDVGT
CCCHHHHHCCEEECCCEEEEEECCHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCEEHHH
FTAEYAGCGTQAYCEILYKVVGKGTKLLSALHHGDVVDLLAPLGRGFDLGPAGEEKVLVG
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEE
GGVGLAPLYYLAKALVARGEKVRLFAGGRNRDDILCITEFERLGVETYVATDDGTLGESG
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHHCCCEEEEECCCCCCCCCH
FVTQVLERHLNKGMRIFACGPTPMLGAVAKMAALHEVPCQVSMEAYMACGVGACLGCVMK
HHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GANHTEDTPDYRCVCKDGPVFDSFELQWS
CCCCCCCCCCEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1709162; 9384377; 8759868; 10545205 [H]