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The map label for this gene is wecB-1 [H]

Identifier: 197118759

GI number: 197118759

Start: 2755573

End: 2756664

Strand: Reverse

Name: wecB-1 [H]

Synonym: Gbem_2378

Alternate gene names: 197118759

Gene position: 2756664-2755573 (Counterclockwise)

Preceding gene: 197118767

Following gene: 197118757

Centisome position: 59.73

GC content: 59.71

Gene sequence:

>1092_bases
ATGAACGTCCTTCTCATCGCAGGTGCCAGGCCCAATTTCATGAAGATCGCTCCTATTTACCGCGCTTCCCTTGACTACCC
TTCGGTGGCATGCAGCATCGTTCACACCGGACAGCATTACGACAAGGAGATGTCCGGCACCTTCTTCGCTGAACTGGAAA
TACCCGAGCCGCGCTATTCGCTGAACGTCGGCTCGGGAAGCCACGCGGAGCAAACGGCTGCCATCATGGTCGCCTTCGAA
GAGGTCTGCCTGCAGGAATCGCCAGACCTCGTGCTGGTGGTGGGTGACGTAAACTCGACCCTTGCCTGCAGTATCGTGGC
GAAAAAGTGCGGGGTTGCGGTGGCGCACGTCGAGGCGGGGTTACGGAGTTTCGACCTGGCCATGCCGGAGGAGATCAACC
GCATGGTGACCGACGCCATCTCCGACAGCTTCTTCGTTACCGAGGAAAGCGGCGTAGAGAACCTGCTTAGGGAAGGAAAA
CAACCGGAACGGATTCATGCGGTGGGGCACGTGATGATCGACAACCTGTTGCGGCAGGTGAAGCTTCTGGAGGGGATAGA
CTTATCCAGCTTCGATAGCCACCGTCTCAAGAAGGAGGCGGGGACCTATCTCTTTCTCACCCTGCACCGCCCCTCCAATG
TGGACTCCAGGGAGACGTTCGCGGGGATCGCCGAGGCCATCAACGAGTTGGCCCGCCAAAGGACAATCTTCTTCCCGGTC
CATCCTCGCACCAGGAATATGATGAGCGCACACGGCATCGAGTTGAGCGACAAGGTGGTCCTCCTGCCGCCGCTTGGCTA
TCGGGAGGCGCTCTTTCTCTGGAAAGACGCCGAAGCTGTCCTTACCGACAGCGGAGGGCTCCAGGAGGAAACCACCGCGC
TTGGGGTTCCCTGCGTAACTATCCGGGAGAATACCGAGCGTCCTGTCACGGTAGAGATTGGGACCAATGTCCTTGCCGGT
ACGGCACCTGAAAAGATCCTCGCGGGATACCGGCTAAGCCTGGAGAAGCGGGGGCGGGCCAGGGTACCGCAGTTGTGGGA
CGGCAGGGCCGCCGAGCGCATCTGGCAGGTATTGGCTGGAGAAGGTCGATGA

Upstream 100 bases:

>100_bases
GGGTCAGGCTGCTGCGACCACGACGCCCGTCCCCTTGCACACCGTTTCGCCCTACCTAACTCTAACCCGGCTCTTGCCGC
CGGATCTCGGAGGAAACCTA

Downstream 100 bases:

>100_bases
AACTCGCATCAGGGCTTTATGAAGATCAAGCCGTAGTGATAGGGGGGAAGGTCGTGGCTGCCACCTTGGTTGAAGCAAAA
TCCCGCCTCCTTTGCCCATG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNVLLIAGARPNFMKIAPIYRASLDYPSVACSIVHTGQHYDKEMSGTFFAELEIPEPRYSLNVGSGSHAEQTAAIMVAFE
EVCLQESPDLVLVVGDVNSTLACSIVAKKCGVAVAHVEAGLRSFDLAMPEEINRMVTDAISDSFFVTEESGVENLLREGK
QPERIHAVGHVMIDNLLRQVKLLEGIDLSSFDSHRLKKEAGTYLFLTLHRPSNVDSRETFAGIAEAINELARQRTIFFPV
HPRTRNMMSAHGIELSDKVVLLPPLGYREALFLWKDAEAVLTDSGGLQEETTALGVPCVTIRENTERPVTVEIGTNVLAG
TAPEKILAGYRLSLEKRGRARVPQLWDGRAAERIWQVLAGEGR

Sequences:

>Translated_363_residues
MNVLLIAGARPNFMKIAPIYRASLDYPSVACSIVHTGQHYDKEMSGTFFAELEIPEPRYSLNVGSGSHAEQTAAIMVAFE
EVCLQESPDLVLVVGDVNSTLACSIVAKKCGVAVAHVEAGLRSFDLAMPEEINRMVTDAISDSFFVTEESGVENLLREGK
QPERIHAVGHVMIDNLLRQVKLLEGIDLSSFDSHRLKKEAGTYLFLTLHRPSNVDSRETFAGIAEAINELARQRTIFFPV
HPRTRNMMSAHGIELSDKVVLLPPLGYREALFLWKDAEAVLTDSGGLQEETTALGVPCVTIRENTERPVTVEIGTNVLAG
TAPEKILAGYRLSLEKRGRARVPQLWDGRAAERIWQVLAGEGR
>Mature_363_residues
MNVLLIAGARPNFMKIAPIYRASLDYPSVACSIVHTGQHYDKEMSGTFFAELEIPEPRYSLNVGSGSHAEQTAAIMVAFE
EVCLQESPDLVLVVGDVNSTLACSIVAKKCGVAVAHVEAGLRSFDLAMPEEINRMVTDAISDSFFVTEESGVENLLREGK
QPERIHAVGHVMIDNLLRQVKLLEGIDLSSFDSHRLKKEAGTYLFLTLHRPSNVDSRETFAGIAEAINELARQRTIFFPV
HPRTRNMMSAHGIELSDKVVLLPPLGYREALFLWKDAEAVLTDSGGLQEETTALGVPCVTIRENTERPVTVEIGTNVLAG
TAPEKILAGYRLSLEKRGRARVPQLWDGRAAERIWQVLAGEGR

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) to produce UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=391, Percent_Identity=34.0153452685422, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 39934; Mature: 39934

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLLIAGARPNFMKIAPIYRASLDYPSVACSIVHTGQHYDKEMSGTFFAELEIPEPRYS
CCEEEEECCCCCCEEECHHHCCCCCCCCCEEEEEECCCHHCCCCCCEEEEEEECCCCCEE
LNVGSGSHAEQTAAIMVAFEEVCLQESPDLVLVVGDVNSTLACSIVAKKCGVAVAHVEAG
EECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCEEEEHHHHC
LRSFDLAMPEEINRMVTDAISDSFFVTEESGVENLLREGKQPERIHAVGHVMIDNLLRQV
HHHHCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KLLEGIDLSSFDSHRLKKEAGTYLFLTLHRPSNVDSRETFAGIAEAINELARQRTIFFPV
HHHHCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEC
HPRTRNMMSAHGIELSDKVVLLPPLGYREALFLWKDAEAVLTDSGGLQEETTALGVPCVT
CCCCCCHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCEEEECCCCCCCCHHHCCCCEEE
IRENTERPVTVEIGTNVLAGTAPEKILAGYRLSLEKRGRARVPQLWDGRAAERIWQVLAG
EECCCCCCEEEEECCCEECCCCHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
EGR
CCC
>Mature Secondary Structure
MNVLLIAGARPNFMKIAPIYRASLDYPSVACSIVHTGQHYDKEMSGTFFAELEIPEPRYS
CCEEEEECCCCCCEEECHHHCCCCCCCCCEEEEEECCCHHCCCCCCEEEEEEECCCCCEE
LNVGSGSHAEQTAAIMVAFEEVCLQESPDLVLVVGDVNSTLACSIVAKKCGVAVAHVEAG
EECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCEEEEHHHHC
LRSFDLAMPEEINRMVTDAISDSFFVTEESGVENLLREGKQPERIHAVGHVMIDNLLRQV
HHHHCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KLLEGIDLSSFDSHRLKKEAGTYLFLTLHRPSNVDSRETFAGIAEAINELARQRTIFFPV
HHHHCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEC
HPRTRNMMSAHGIELSDKVVLLPPLGYREALFLWKDAEAVLTDSGGLQEETTALGVPCVT
CCCCCCHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCEEEECCCCCCCCHHHCCCCEEE
IRENTERPVTVEIGTNVLAGTAPEKILAGYRLSLEKRGRARVPQLWDGRAAERIWQVLAG
EECCCCCCEEEEECCCEECCCCHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCC
EGR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]