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The map label for this gene is mscS [C]

Identifier: 197118713

GI number: 197118713

Start: 2706251

End: 2707339

Strand: Reverse

Name: mscS [C]

Synonym: Gbem_2332

Alternate gene names: 197118713

Gene position: 2707339-2706251 (Counterclockwise)

Preceding gene: 197118714

Following gene: 197118712

Centisome position: 58.66

GC content: 60.42

Gene sequence:

>1089_bases
GTGGATAGCCTTTTGTACTACCTGACGCCCAACGAGATGGATCCCTTCTATCTCTTCTGGGCCAAGCAACTGTTCATATC
GGTCGGTATCATCGCCGGCTTTTATCTCCTATCGAGGCTCCTGCAGCGGGTCCTGGCCAAGGTCGGGACTCGCCTGTGCG
CCTATACGGAGACGGACCTCGACGACCGGATACTGGAGATCGTCTCCGGCCCGGTCATGGTCCTGGTCAACTGCGCCGGC
CTCTACTTCGCCATCAAGCGTCTGCCGCTCCCCGAAAGAATCGGGGTGATAGCGGCCGGCATCCTGTTCGTGATCAACAT
CGCCATCATCACCACGGTCGCGTTCCGGATCGTCAACGAGATGCTTGAGCGTTTCGGCGACCGGGTCGCCGGCCCGGAGA
TGAGCCGCCAGCTGATGCCGCTGATCGAGAAGCTCTGCACCATCTTCCTGATCATCACGGCGCTCATCATCACCCTCAAG
CACTTCAACTACGACATCCTCTCCCTGGTGACGGCTCTGGGGGTCGGCTCTCTGGCCATCGGTCTCGCCGCCAAGGACAC
GCTGGCCAACATGATCTCCGGGTTCACGCTGATGCTCGACCGTCCCTTCCGGATCGGCGACAGGATTCAGGTTGCCTCCC
AGACCGGCGACGTGGTCGACATCGGCCTTCGCAGCACCAAAATCAAGGCGCTGGACAACACCTTCCTGATCATCCCCAAC
GCCGACCTGTGCAACTCCACCGTCATCAACCAGGCTTTCCCCGACGTCCGCGGCAAAGGCAGGATCAACATCGGCATCGG
CTACGACTGCGACCCGGAGCGGGCCAAGGAACTCCTGGTCCGAACCGCCAAGTCGGCGCCGAACGTTCTTGCCGAACCGG
CTCCCGAGGCGTACTTCATGAATTTCGGCGACAGCGCCCTGAACCTCTCGCTCTTCTTCTGGGTCGCCGACTACACCCAT
CTCGTCAAGGCGACCGACCAGATCAACTGCGCCCTGGTGAAATGCTTCCAGGACAACGGCGTCAACATACCGTACCCGAC
GCGGACGGTCATATATGAAAAGGACACAGACCATGCCCCACAGGATTGA

Upstream 100 bases:

>100_bases
GCCGATGTCGCCGGGTTCCTTCCCGCCGAGGAGATCAAGGAAGCCTTCGATCTCGGTTACCATTTGAAACACGTCGACAC
TATTTTCACGAGGGTCTTCG

Downstream 100 bases:

>100_bases
AATCACCCTAAAGGACGAGGTCCGCGACCCTCGCGGCGAACGGATCAAACGGGAGATCGAGCACTTTCTCCATCTCAACG
TGGACCAGGTCCGGACCATA

Product: small-conductance mechanosensitive ion channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MDSLLYYLTPNEMDPFYLFWAKQLFISVGIIAGFYLLSRLLQRVLAKVGTRLCAYTETDLDDRILEIVSGPVMVLVNCAG
LYFAIKRLPLPERIGVIAAGILFVINIAIITTVAFRIVNEMLERFGDRVAGPEMSRQLMPLIEKLCTIFLIITALIITLK
HFNYDILSLVTALGVGSLAIGLAAKDTLANMISGFTLMLDRPFRIGDRIQVASQTGDVVDIGLRSTKIKALDNTFLIIPN
ADLCNSTVINQAFPDVRGKGRINIGIGYDCDPERAKELLVRTAKSAPNVLAEPAPEAYFMNFGDSALNLSLFFWVADYTH
LVKATDQINCALVKCFQDNGVNIPYPTRTVIYEKDTDHAPQD

Sequences:

>Translated_362_residues
MDSLLYYLTPNEMDPFYLFWAKQLFISVGIIAGFYLLSRLLQRVLAKVGTRLCAYTETDLDDRILEIVSGPVMVLVNCAG
LYFAIKRLPLPERIGVIAAGILFVINIAIITTVAFRIVNEMLERFGDRVAGPEMSRQLMPLIEKLCTIFLIITALIITLK
HFNYDILSLVTALGVGSLAIGLAAKDTLANMISGFTLMLDRPFRIGDRIQVASQTGDVVDIGLRSTKIKALDNTFLIIPN
ADLCNSTVINQAFPDVRGKGRINIGIGYDCDPERAKELLVRTAKSAPNVLAEPAPEAYFMNFGDSALNLSLFFWVADYTH
LVKATDQINCALVKCFQDNGVNIPYPTRTVIYEKDTDHAPQD
>Mature_362_residues
MDSLLYYLTPNEMDPFYLFWAKQLFISVGIIAGFYLLSRLLQRVLAKVGTRLCAYTETDLDDRILEIVSGPVMVLVNCAG
LYFAIKRLPLPERIGVIAAGILFVINIAIITTVAFRIVNEMLERFGDRVAGPEMSRQLMPLIEKLCTIFLIITALIITLK
HFNYDILSLVTALGVGSLAIGLAAKDTLANMISGFTLMLDRPFRIGDRIQVASQTGDVVDIGLRSTKIKALDNTFLIIPN
ADLCNSTVINQAFPDVRGKGRINIGIGYDCDPERAKELLVRTAKSAPNVLAEPAPEAYFMNFGDSALNLSLFFWVADYTH
LVKATDQINCALVKCFQDNGVNIPYPTRTVIYEKDTDHAPQD

Specific function: Unknown

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1786670, Length=184, Percent_Identity=30.9782608695652, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787591, Length=262, Percent_Identity=27.8625954198473, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI2367355, Length=178, Percent_Identity=28.6516853932584, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789291, Length=280, Percent_Identity=23.2142857142857, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 40123; Mature: 40123

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLLYYLTPNEMDPFYLFWAKQLFISVGIIAGFYLLSRLLQRVLAKVGTRLCAYTETDL
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DDRILEIVSGPVMVLVNCAGLYFAIKRLPLPERIGVIAAGILFVINIAIITTVAFRIVNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLERFGDRVAGPEMSRQLMPLIEKLCTIFLIITALIITLKHFNYDILSLVTALGVGSLAI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHH
GLAAKDTLANMISGFTLMLDRPFRIGDRIQVASQTGDVVDIGLRSTKIKALDNTFLIIPN
HHHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCEEEECCCCEEEEEECCEEEEEEC
ADLCNSTVINQAFPDVRGKGRINIGIGYDCDPERAKELLVRTAKSAPNVLAEPAPEAYFM
CCHHCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
NFGDSALNLSLFFWVADYTHLVKATDQINCALVKCFQDNGVNIPYPTRTVIYEKDTDHAP
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCC
QD
CC
>Mature Secondary Structure
MDSLLYYLTPNEMDPFYLFWAKQLFISVGIIAGFYLLSRLLQRVLAKVGTRLCAYTETDL
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
DDRILEIVSGPVMVLVNCAGLYFAIKRLPLPERIGVIAAGILFVINIAIITTVAFRIVNE
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLERFGDRVAGPEMSRQLMPLIEKLCTIFLIITALIITLKHFNYDILSLVTALGVGSLAI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHH
GLAAKDTLANMISGFTLMLDRPFRIGDRIQVASQTGDVVDIGLRSTKIKALDNTFLIIPN
HHHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCCCEEEECCCCEEEEEECCEEEEEEC
ADLCNSTVINQAFPDVRGKGRINIGIGYDCDPERAKELLVRTAKSAPNVLAEPAPEAYFM
CCHHCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEE
NFGDSALNLSLFFWVADYTHLVKATDQINCALVKCFQDNGVNIPYPTRTVIYEKDTDHAP
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEECCCCCCC
QD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]