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The map label for this gene is coaX

Identifier: 197118700

GI number: 197118700

Start: 2692630

End: 2693394

Strand: Reverse

Name: coaX

Synonym: Gbem_2319

Alternate gene names: 197118700

Gene position: 2693394-2692630 (Counterclockwise)

Preceding gene: 197118701

Following gene: 197118699

Centisome position: 58.36

GC content: 59.87

Gene sequence:

>765_bases
TTGCTTTTGGTTATCGACGTCGGGAACAGCAACATCGTTCTCGGGATATACGATGAAGAACGCCTGGTCCGGGACTGGAG
GGTATCCACCGACAAGTCCAAGACTATCGACGAGTACGGCATCTTGTTCCACGACCTGTTCCGCCTGGCGGACATCGTCT
TCACCGACGTGAAGGACATCATCATCTCCTCGGTGGTGCCGACCCTAACCGGCGTGCTGGAGAAGCTCTCCCGCCAGTAC
TTCAAGATTTCGCCTTACGTGGTCGGCCCCGGCATCAAGACCGGCATGCCGATCCACTACGATAACCCCAAGGAAGTCGG
GGCGGACCGCATCGTTAACGCCATCGCCGGGTTCGAGAAGTACCGCACGGCGCTCATCATCGTCGATTTCGGCACCGCCA
CCACCTTCGACTACGTCAACAAGAAGGGTGAGTACTGCGGCGGCGCCATCGCACCGGGGCTCGCCATCTCCATGGAGGCC
CTGTTCATGAAGGCGAGCAAGCTGCCGCGGGTCGATATCGCCCGCCCCCCCAGCATCATCGCCAAGAACACGGTGAACTC
CATGCAGGCCGGGATCTTCTTCGGCTACGTGGGGCTTGTGGACGGGATCGTGCAACGGATGAAAGGGGAGGGGAAGGAGA
ACCCCAAGGTAATCGCCACCGGGGGGCTCGCCTCCCTGATAGCGCCTGAGTCCGTCACCATCGAGGAGGTGGACGAGTTC
CTCACCTTGGAGGGGCTGCGCATCATCTACCAGAGGAATAAATAA

Upstream 100 bases:

>100_bases
TCACGCAAAGCCGCGAAGGCGCAAAGAAAGACGAAACTAAATGAGTAGGTCTCGAAGGTTTGCTTTGCGCCTTTGCGGCT
TTGCGTGAGGAGGTTCGGGT

Downstream 100 bases:

>100_bases
GTAACCAACGCCCTCAGGGCACAAGGAGGAGGTCCCCCCATCGAGATTCGTACCGCCGGGTAGTTTGTTGTTGGTTTCGT
CTGCTTTACTCAAGTCAGAT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MLLVIDVGNSNIVLGIYDEERLVRDWRVSTDKSKTIDEYGILFHDLFRLADIVFTDVKDIIISSVVPTLTGVLEKLSRQY
FKISPYVVGPGIKTGMPIHYDNPKEVGADRIVNAIAGFEKYRTALIIVDFGTATTFDYVNKKGEYCGGAIAPGLAISMEA
LFMKASKLPRVDIARPPSIIAKNTVNSMQAGIFFGYVGLVDGIVQRMKGEGKENPKVIATGGLASLIAPESVTIEEVDEF
LTLEGLRIIYQRNK

Sequences:

>Translated_254_residues
MLLVIDVGNSNIVLGIYDEERLVRDWRVSTDKSKTIDEYGILFHDLFRLADIVFTDVKDIIISSVVPTLTGVLEKLSRQY
FKISPYVVGPGIKTGMPIHYDNPKEVGADRIVNAIAGFEKYRTALIIVDFGTATTFDYVNKKGEYCGGAIAPGLAISMEA
LFMKASKLPRVDIARPPSIIAKNTVNSMQAGIFFGYVGLVDGIVQRMKGEGKENPKVIATGGLASLIAPESVTIEEVDEF
LTLEGLRIIYQRNK
>Mature_254_residues
MLLVIDVGNSNIVLGIYDEERLVRDWRVSTDKSKTIDEYGILFHDLFRLADIVFTDVKDIIISSVVPTLTGVLEKLSRQY
FKISPYVVGPGIKTGMPIHYDNPKEVGADRIVNAIAGFEKYRTALIIVDFGTATTFDYVNKKGEYCGGAIAPGLAISMEA
LFMKASKLPRVDIARPPSIIAKNTVNSMQAGIFFGYVGLVDGIVQRMKGEGKENPKVIATGGLASLIAPESVTIEEVDEF
LTLEGLRIIYQRNK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_GEOBB (B5EF22)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002139127.1
- ProteinModelPortal:   B5EF22
- GeneID:   6782315
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_2319
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27938; Mature: 27938

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDVGNSNIVLGIYDEERLVRDWRVSTDKSKTIDEYGILFHDLFRLADIVFTDVKDI
CEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISSVVPTLTGVLEKLSRQYFKISPYVVGPGIKTGMPIHYDNPKEVGADRIVNAIAGFEK
HHHHHHHHHHHHHHHHHHHHEEECCEEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHH
YRTALIIVDFGTATTFDYVNKKGEYCGGAIAPGLAISMEALFMKASKLPRVDIARPPSII
HCEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHH
AKNTVNSMQAGIFFGYVGLVDGIVQRMKGEGKENPKVIATGGLASLIAPESVTIEEVDEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHH
LTLEGLRIIYQRNK
HHHHHEEEEEECCC
>Mature Secondary Structure
MLLVIDVGNSNIVLGIYDEERLVRDWRVSTDKSKTIDEYGILFHDLFRLADIVFTDVKDI
CEEEEEECCCEEEEEEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IISSVVPTLTGVLEKLSRQYFKISPYVVGPGIKTGMPIHYDNPKEVGADRIVNAIAGFEK
HHHHHHHHHHHHHHHHHHHHEEECCEEECCCCCCCCCEECCCHHHHHHHHHHHHHHHHHH
YRTALIIVDFGTATTFDYVNKKGEYCGGAIAPGLAISMEALFMKASKLPRVDIARPPSII
HCEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHH
AKNTVNSMQAGIFFGYVGLVDGIVQRMKGEGKENPKVIATGGLASLIAPESVTIEEVDEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHCCCCCCHHHHHHH
LTLEGLRIIYQRNK
HHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA