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The map label for this gene is 197118471

Identifier: 197118471

GI number: 197118471

Start: 2415453

End: 2416304

Strand: Direct

Name: 197118471

Synonym: Gbem_2089

Alternate gene names: NA

Gene position: 2415453-2416304 (Clockwise)

Preceding gene: 197118469

Following gene: 197118476

Centisome position: 52.34

GC content: 59.86

Gene sequence:

>852_bases
ATGTTGGACCGCTCAAAGTACTCCTGCTACACTGCGCACCTGTCAGCACCCGGCTCTGACCGGCATCCTTTCCTCTTAGT
GGTATTCATGCGTCGACTCTGTCTTCATTCCTTGTTGCTGGTACTGTTTACCGCTGTTTCCGTCTTTGCCGGCCCCCTCG
ACGACTGCCGCGAGTACACGCAGTTTGGCGTCCCTGGCACCTCTGGCGATCTCCTTTGCCGCAAGGGATACCTGCTCTCG
CACGACGCCAAGCGCAAGACCCCGGTCTGGGTCGTCGAGCGCATGACACGGGAGCGGCTAAAGGCGGTCCTGAAGCGCTC
CGACCGTTTCGTGCCTGATGCGGAACTGCCCAAAGGGCAGCGGGCGGAACTGTCGGACTACAAAGGATCGGGATACGACC
GGGGGCACATGGCCCCAGCGGCGGACATGGCATGGGATGCAGCCGCCATGTCGGAGAGTTTCTATCTATCCAACATGGTT
CCCCAGGCGGGGGAGGGGATGAATCGTGGTATCTGGGCCGAGTTGGAAAAGAAGGTGCGCCAGTGGGTGGAGAAGCGGGG
GGGACTTTACATCTACAGCGGGCCGATCTACGGCGAAGGTGAAGTGAAAACCATCGGCCGCAACAAGGTGGCAGTACCGG
ATGCTCTTTTCAAAGTGGTCCTCGATCCGGTAAGGCACGAAGCAATCGCGGTGGTCATGCCCAATCGTCCGCTCGACACC
CGCGACATGCCGAAGTACCTGGTTCCGGTCCGCGAGGTGGAAAAACTGACCGGCCTTGAGTTCTTCTCCACACTTCCCCA
GGAGGAGCAGGACCTGATCGAGGTTCCCAAGCCTGAGGCCCTGTGGCAATAA

Upstream 100 bases:

>100_bases
GTCTAATTCAGATTCTTATGATAATACATATTTCTCCTATGTAAACCTCCCCACGGATTTTTTGCCTGCTGATGCAGACC
TGCTTTAGAGATCCCAGATA

Downstream 100 bases:

>100_bases
AAAAAAGGAAAAGTAGCCTGTCCCCCTTTATCTTCTCTTCACCGCGGCGCCGATGAACTCGGCCGCATCCTTTTTCAACT
GAGCCAGTGACTCTTTTTCC

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLDRSKYSCYTAHLSAPGSDRHPFLLVVFMRRLCLHSLLLVLFTAVSVFAGPLDDCREYTQFGVPGTSGDLLCRKGYLLS
HDAKRKTPVWVVERMTRERLKAVLKRSDRFVPDAELPKGQRAELSDYKGSGYDRGHMAPAADMAWDAAAMSESFYLSNMV
PQAGEGMNRGIWAELEKKVRQWVEKRGGLYIYSGPIYGEGEVKTIGRNKVAVPDALFKVVLDPVRHEAIAVVMPNRPLDT
RDMPKYLVPVREVEKLTGLEFFSTLPQEEQDLIEVPKPEALWQ

Sequences:

>Translated_283_residues
MLDRSKYSCYTAHLSAPGSDRHPFLLVVFMRRLCLHSLLLVLFTAVSVFAGPLDDCREYTQFGVPGTSGDLLCRKGYLLS
HDAKRKTPVWVVERMTRERLKAVLKRSDRFVPDAELPKGQRAELSDYKGSGYDRGHMAPAADMAWDAAAMSESFYLSNMV
PQAGEGMNRGIWAELEKKVRQWVEKRGGLYIYSGPIYGEGEVKTIGRNKVAVPDALFKVVLDPVRHEAIAVVMPNRPLDT
RDMPKYLVPVREVEKLTGLEFFSTLPQEEQDLIEVPKPEALWQ
>Mature_283_residues
MLDRSKYSCYTAHLSAPGSDRHPFLLVVFMRRLCLHSLLLVLFTAVSVFAGPLDDCREYTQFGVPGTSGDLLCRKGYLLS
HDAKRKTPVWVVERMTRERLKAVLKRSDRFVPDAELPKGQRAELSDYKGSGYDRGHMAPAADMAWDAAAMSESFYLSNMV
PQAGEGMNRGIWAELEKKVRQWVEKRGGLYIYSGPIYGEGEVKTIGRNKVAVPDALFKVVLDPVRHEAIAVVMPNRPLDT
RDMPKYLVPVREVEKLTGLEFFSTLPQEEQDLIEVPKPEALWQ

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI53759134, Length=222, Percent_Identity=35.5855855855856, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI224451073, Length=222, Percent_Identity=35.1351351351351, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI224451075, Length=173, Percent_Identity=36.9942196531792, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17505967, Length=224, Percent_Identity=37.9464285714286, Blast_Score=140, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6322253, Length=236, Percent_Identity=35.1694915254237, Blast_Score=135, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24581065, Length=226, Percent_Identity=33.6283185840708, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI20129899, Length=258, Percent_Identity=33.3333333333333, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI28571642, Length=241, Percent_Identity=26.5560165975104, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24581067, Length=263, Percent_Identity=28.8973384030418, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: NA

Molecular weight: Translated: 31989; Mature: 31989

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS01070 NUCLEASE_NON_SPEC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRSKYSCYTAHLSAPGSDRHPFLLVVFMRRLCLHSLLLVLFTAVSVFAGPLDDCREYT
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QFGVPGTSGDLLCRKGYLLSHDAKRKTPVWVVERMTRERLKAVLKRSDRFVPDAELPKGQ
HCCCCCCCCCCEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RAELSDYKGSGYDRGHMAPAADMAWDAAAMSESFYLSNMVPQAGEGMNRGIWAELEKKVR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
QWVEKRGGLYIYSGPIYGEGEVKTIGRNKVAVPDALFKVVLDPVRHEAIAVVMPNRPLDT
HHHHHCCCEEEECCCEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
RDMPKYLVPVREVEKLTGLEFFSTLPQEEQDLIEVPKPEALWQ
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHCCC
>Mature Secondary Structure
MLDRSKYSCYTAHLSAPGSDRHPFLLVVFMRRLCLHSLLLVLFTAVSVFAGPLDDCREYT
CCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QFGVPGTSGDLLCRKGYLLSHDAKRKTPVWVVERMTRERLKAVLKRSDRFVPDAELPKGQ
HCCCCCCCCCCEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
RAELSDYKGSGYDRGHMAPAADMAWDAAAMSESFYLSNMVPQAGEGMNRGIWAELEKKVR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
QWVEKRGGLYIYSGPIYGEGEVKTIGRNKVAVPDALFKVVLDPVRHEAIAVVMPNRPLDT
HHHHHCCCEEEECCCEECCCCEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCC
RDMPKYLVPVREVEKLTGLEFFSTLPQEEQDLIEVPKPEALWQ
CCCHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]