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The map label for this gene is yabD [H]

Identifier: 197118432

GI number: 197118432

Start: 2362993

End: 2364369

Strand: Reverse

Name: yabD [H]

Synonym: Gbem_2050

Alternate gene names: 197118432

Gene position: 2364369-2362993 (Counterclockwise)

Preceding gene: 197118433

Following gene: 197118430

Centisome position: 51.23

GC content: 63.25

Gene sequence:

>1377_bases
ATGGAACTGATCGACAGCCACGCGCACATATATGGCAAGGAGTACGCGGCCGATTTCGAGGAGATGATGGAGAGGGCCGC
GGAGGCTGGAGTCGGCACCATCGTGGCGGTGGGAGCCGACCTGGAATCTAGCCAGGAAGCGCTCGCCCTTGCCGGGGCGC
GCGAAAACGTCTACTGCTCGGTCGGCATTCATCCGCACGACGCGGACCGGGTGACCGAGCGCTGCTACGAACTGGTCCGC
GAGATGGCGCTCTCAAGCCCCAAGGTGGTCGCCATCGGCGAAATCGGCCTCGACTTCTTCAGGGACCGCTCCTCGCGCGA
AAACCAGGAGGAGGTCTTCCGGCGCTTCATCAGGATGGGGCGCGAATTGTCTCTGCCGCTGATCATCCACGACCGTGACG
CCCACGACAGGATCATGGCGATCCTCAGGGAGGAGAAAGCCGGCGAGGTAGGAGGCGTGCTGCACTGCTTTTCCGGCGAC
CTCGCCATGGCGCAGGAGTGCATCGAGCTCGGATTCAAGATCTCCATCCCGGGGACGGTCACCTACCCCTCCAACGAGGC
GCTCAGGGAAGTGGTGCGCGGGGTAAAGATCGAGCAGCTCATGGTGGAGACGGACGCCCCCTACCTGACGCCGGTGCCGC
ACCGCGGCAAGAGGAACGAGCCGGCCTTCGTGCGGCTTACGGCCGAGAGGGTGGCGCAGGTCAAGGGGCTTTCCCCCGAG
GACGTCGGCAGGATCACCTCGTTCAACACCAGGAAGCTCTTCGGGATCCCGCAACCGGCCGAGCAGGACACCATTGCCTA
CATGATCCGCAACTCACTCTACCTGAATATCACCAACCGCTGCTCGAACCGCTGCACCTTCTGCCCCAAGTTCGACGATT
TCGCGGTGAAGGGTCATGAGCTGAAGCTCTCCCACGAACCGAACTTCGCCGAGGTGATGGCTGCGGTAGACAGGGCCTCC
GGTTTCGAAGAGGTGGTTTTCTGCGGCTACGGCGAACCGCTGGTCCGGCTCGACCTGGTGAAGGAGGTGGCTGCCGAATT
AAAGCGTCGCGGCATCAAGGTCCGGATCAACACGGACGGGCAGGCGAACCTCGTGCACGGCAGGAACATCCTCCCCGAAC
TGGCAGGCCTTGTGGACGTCCTCTCGGTGAGCCTCAACGCCGCCAACGCCGAAGATTACCAGCGGTTGTGCAATACCCCC
TTCGGAGCGGCAGGCTTCCAGGGTGTCTGCGATTTCCTCAGGGAAGCGCCCAAGCACGTGCCTCAGGTGACGGCAAGCGC
AGTAACGGTGCCGGGACTGGATGTCGGAAAGGTGCGGGAACTGGCGCTGTCGCTGGGAGTGGATTACCGCGAGAGGGAGT
ACGCGGAGGTAGGTTGA

Upstream 100 bases:

>100_bases
AACCCCCTCCCGCAAGGGGAGGTGGGACCAATAGCGACTTCCCCGGAAATTTCTTCGAACCTTGCTAAAGGCGGACTTTT
AGCACAAAGGAGCAACCGAC

Downstream 100 bases:

>100_bases
AAGGGGCGGTGAGGCATCAATCGACGGCGAACTCGCCGGCATCGGCGGGAGCCTGCGAAGGTAAAACCATGGCCTTGGCG
GCACCAGGGAGGGTGAAGTA

Product: bifunctional TatD family magnesium-dependent deoxyribonuclease/radical SAM domain iron-sulfur oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MELIDSHAHIYGKEYAADFEEMMERAAEAGVGTIVAVGADLESSQEALALAGARENVYCSVGIHPHDADRVTERCYELVR
EMALSSPKVVAIGEIGLDFFRDRSSRENQEEVFRRFIRMGRELSLPLIIHDRDAHDRIMAILREEKAGEVGGVLHCFSGD
LAMAQECIELGFKISIPGTVTYPSNEALREVVRGVKIEQLMVETDAPYLTPVPHRGKRNEPAFVRLTAERVAQVKGLSPE
DVGRITSFNTRKLFGIPQPAEQDTIAYMIRNSLYLNITNRCSNRCTFCPKFDDFAVKGHELKLSHEPNFAEVMAAVDRAS
GFEEVVFCGYGEPLVRLDLVKEVAAELKRRGIKVRINTDGQANLVHGRNILPELAGLVDVLSVSLNAANAEDYQRLCNTP
FGAAGFQGVCDFLREAPKHVPQVTASAVTVPGLDVGKVRELALSLGVDYREREYAEVG

Sequences:

>Translated_458_residues
MELIDSHAHIYGKEYAADFEEMMERAAEAGVGTIVAVGADLESSQEALALAGARENVYCSVGIHPHDADRVTERCYELVR
EMALSSPKVVAIGEIGLDFFRDRSSRENQEEVFRRFIRMGRELSLPLIIHDRDAHDRIMAILREEKAGEVGGVLHCFSGD
LAMAQECIELGFKISIPGTVTYPSNEALREVVRGVKIEQLMVETDAPYLTPVPHRGKRNEPAFVRLTAERVAQVKGLSPE
DVGRITSFNTRKLFGIPQPAEQDTIAYMIRNSLYLNITNRCSNRCTFCPKFDDFAVKGHELKLSHEPNFAEVMAAVDRAS
GFEEVVFCGYGEPLVRLDLVKEVAAELKRRGIKVRINTDGQANLVHGRNILPELAGLVDVLSVSLNAANAEDYQRLCNTP
FGAAGFQGVCDFLREAPKHVPQVTASAVTVPGLDVGKVRELALSLGVDYREREYAEVG
>Mature_458_residues
MELIDSHAHIYGKEYAADFEEMMERAAEAGVGTIVAVGADLESSQEALALAGARENVYCSVGIHPHDADRVTERCYELVR
EMALSSPKVVAIGEIGLDFFRDRSSRENQEEVFRRFIRMGRELSLPLIIHDRDAHDRIMAILREEKAGEVGGVLHCFSGD
LAMAQECIELGFKISIPGTVTYPSNEALREVVRGVKIEQLMVETDAPYLTPVPHRGKRNEPAFVRLTAERVAQVKGLSPE
DVGRITSFNTRKLFGIPQPAEQDTIAYMIRNSLYLNITNRCSNRCTFCPKFDDFAVKGHELKLSHEPNFAEVMAAVDRAS
GFEEVVFCGYGEPLVRLDLVKEVAAELKRRGIKVRINTDGQANLVHGRNILPELAGLVDVLSVSLNAANAEDYQRLCNTP
FGAAGFQGVCDFLREAPKHVPQVTASAVTVPGLDVGKVRELALSLGVDYREREYAEVG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=270, Percent_Identity=28.8888888888889, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI110349734, Length=265, Percent_Identity=30.188679245283, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI110349730, Length=265, Percent_Identity=29.811320754717, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=29.8892988929889, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI225903439, Length=248, Percent_Identity=29.0322580645161, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=29.4573643410853, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI225903424, Length=185, Percent_Identity=31.8918918918919, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=27.1929824561404, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=42.0849420849421, Blast_Score=199, Evalue=4e-52,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=35.7692307692308, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=31.25, Blast_Score=145, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=31.2056737588652, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=26.4367816091954, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=31.25, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648690, Length=286, Percent_Identity=30.0699300699301, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24586117, Length=282, Percent_Identity=29.0780141843972, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330018, Length=282, Percent_Identity=29.0780141843972, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 50632; Mature: 50632

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELIDSHAHIYGKEYAADFEEMMERAAEAGVGTIVAVGADLESSQEALALAGARENVYCS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEE
VGIHPHDADRVTERCYELVREMALSSPKVVAIGEIGLDFFRDRSSRENQEEVFRRFIRMG
ECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHHCC
RELSLPLIIHDRDAHDRIMAILREEKAGEVGGVLHCFSGDLAMAQECIELGFKISIPGTV
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCEEECCEEE
TYPSNEALREVVRGVKIEQLMVETDAPYLTPVPHRGKRNEPAFVRLTAERVAQVKGLSPE
ECCCHHHHHHHHCCCCHHHHEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCCHH
DVGRITSFNTRKLFGIPQPAEQDTIAYMIRNSLYLNITNRCSNRCTFCPKFDDFAVKGHE
HHCCCCCCCCCEEECCCCCCCCHHHHHHHHCCEEEEEHHHCCCCCCCCCCCCCCEECCCE
LKLSHEPNFAEVMAAVDRASGFEEVVFCGYGEPLVRLDLVKEVAAELKRRGIKVRINTDG
EEECCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCC
QANLVHGRNILPELAGLVDVLSVSLNAANAEDYQRLCNTPFGAAGFQGVCDFLREAPKHV
CEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
PQVTASAVTVPGLDVGKVRELALSLGVDYREREYAEVG
HHHHHCEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MELIDSHAHIYGKEYAADFEEMMERAAEAGVGTIVAVGADLESSQEALALAGARENVYCS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEE
VGIHPHDADRVTERCYELVREMALSSPKVVAIGEIGLDFFRDRSSRENQEEVFRRFIRMG
ECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHHCC
RELSLPLIIHDRDAHDRIMAILREEKAGEVGGVLHCFSGDLAMAQECIELGFKISIPGTV
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHCCCEEECCEEE
TYPSNEALREVVRGVKIEQLMVETDAPYLTPVPHRGKRNEPAFVRLTAERVAQVKGLSPE
ECCCHHHHHHHHCCCCHHHHEEECCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCCHH
DVGRITSFNTRKLFGIPQPAEQDTIAYMIRNSLYLNITNRCSNRCTFCPKFDDFAVKGHE
HHCCCCCCCCCEEECCCCCCCCHHHHHHHHCCEEEEEHHHCCCCCCCCCCCCCCEECCCE
LKLSHEPNFAEVMAAVDRASGFEEVVFCGYGEPLVRLDLVKEVAAELKRRGIKVRINTDG
EEECCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEEEECCCC
QANLVHGRNILPELAGLVDVLSVSLNAANAEDYQRLCNTPFGAAGFQGVCDFLREAPKHV
CEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
PQVTASAVTVPGLDVGKVRELALSLGVDYREREYAEVG
HHHHHCEEECCCCCHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]