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The map label for this gene is cheB-8 [H]

Identifier: 197118408

GI number: 197118408

Start: 2333190

End: 2334245

Strand: Reverse

Name: cheB-8 [H]

Synonym: Gbem_2026

Alternate gene names: 197118408

Gene position: 2334245-2333190 (Counterclockwise)

Preceding gene: 308535282

Following gene: 197118407

Centisome position: 50.58

GC content: 65.15

Gene sequence:

>1056_bases
ATGATCAGACTACTGGTGGTGGAAGACTCGAAAACGGTGCAGAAGGCTTTGGTGGCGGCCTTTCAGGCGGACCCAGAACT
GCAGGTGATAGGCGTCGCGGAAAGCGGCGAGGAGGCGGTAGAGGCCGCCGCGCGCCTGAAGCCCGACCTGATCACCATGG
ACCTGCACCTCTCCGGAATGAACGGCCTGGACGCGACCCGCGCCATCATGTCCACCTCTCCGGTCCCCATCGTCGTAGTC
TCGGGGAAGATCGACACGCGCGATTCGGACCTCCTCTTCCGCTTCATGGAGGCCGGCGTCCTGATGGTGCTCCCAAAGCC
CGCCCCGGTGGGAACCCCCGGCTACGCTGAGTCGGTGGCGAGCCTGATCCATCACATAAAGCTCATGTCGGAGATCAAGG
TGGTGCGGCGCGTCTTCGCCCCCGGCGCCCTTGGCCAGTGGCCCAAGTCGCCGCTAAAGGAGCCCTTAGCCCCCGTCAAG
GTGGTCGCCATCGGGGCCTCGACCGGCGGTCCCCCGCTGCTGCACCGGATCCTCGCCGCGCTTCCTGAAGATTTCGGGGC
CGCCGTCCTGGTAGTGCAGCACATGTCAGTAGGCTTCACCGAGAACTTCGTGCACTGGCTGAACCTCCACTCGCGGATGC
CGGTGCGGCTTGCCGCCGAAGGGACGGTCATCGCGGCGGGAGAGGTTTACGTGGCGCCGGACGGCTGCCACATGGAAGCT
ACCCCGGCCGGAAGGATCGCCCTCTCCGGCGCCCCCCCCGAAAACGGGGTCCGCCCCTCCATCGACGTCCTCTTCCGCTC
GGTCGCCAAAAGCTACGGCGCCAATGCGGCCGGCATCATCCTCTCCGGGATGGGCAAGGACGGCGCCGTCGAATTGAAGA
CGCTAAAGGGGCGCGGAGGCCTCTGCATCGCGCAGAACCGCGAAAGCTCCATGGTCTTCGGTATGCCCGGAGAAGCGATA
AAGATCGACGCCGTGCAGCACGTGCTCTCCCCCGAGGGGATCATCAACCTGCTTTTGGCGGTTACCAAGAAAGGCGCACA
GGGTGCGTCCAAGTAA

Upstream 100 bases:

>100_bases
GCGGCATCGACGTGGGCGCAAGCGCCTACCTGGTGAAAAGCAGCTTCGACCAAAGCGGCTTGATTGACGTGATACGAAAA
CTGACCTGACTGAGGACCAG

Downstream 100 bases:

>100_bases
GGAAGGAGCTTCATGCAGAAGAGCAACAACGGCCAGACGGCACCATACCTGATCCTGATCGTCGACGACAGCCCGACCCA
GGCGAAACTCCTTGAACAGC

Product: response receiver chemotaxis protein-glutamate methylesterase CheB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MIRLLVVEDSKTVQKALVAAFQADPELQVIGVAESGEEAVEAAARLKPDLITMDLHLSGMNGLDATRAIMSTSPVPIVVV
SGKIDTRDSDLLFRFMEAGVLMVLPKPAPVGTPGYAESVASLIHHIKLMSEIKVVRRVFAPGALGQWPKSPLKEPLAPVK
VVAIGASTGGPPLLHRILAALPEDFGAAVLVVQHMSVGFTENFVHWLNLHSRMPVRLAAEGTVIAAGEVYVAPDGCHMEA
TPAGRIALSGAPPENGVRPSIDVLFRSVAKSYGANAAGIILSGMGKDGAVELKTLKGRGGLCIAQNRESSMVFGMPGEAI
KIDAVQHVLSPEGIINLLLAVTKKGAQGASK

Sequences:

>Translated_351_residues
MIRLLVVEDSKTVQKALVAAFQADPELQVIGVAESGEEAVEAAARLKPDLITMDLHLSGMNGLDATRAIMSTSPVPIVVV
SGKIDTRDSDLLFRFMEAGVLMVLPKPAPVGTPGYAESVASLIHHIKLMSEIKVVRRVFAPGALGQWPKSPLKEPLAPVK
VVAIGASTGGPPLLHRILAALPEDFGAAVLVVQHMSVGFTENFVHWLNLHSRMPVRLAAEGTVIAAGEVYVAPDGCHMEA
TPAGRIALSGAPPENGVRPSIDVLFRSVAKSYGANAAGIILSGMGKDGAVELKTLKGRGGLCIAQNRESSMVFGMPGEAI
KIDAVQHVLSPEGIINLLLAVTKKGAQGASK
>Mature_351_residues
MIRLLVVEDSKTVQKALVAAFQADPELQVIGVAESGEEAVEAAARLKPDLITMDLHLSGMNGLDATRAIMSTSPVPIVVV
SGKIDTRDSDLLFRFMEAGVLMVLPKPAPVGTPGYAESVASLIHHIKLMSEIKVVRRVFAPGALGQWPKSPLKEPLAPVK
VVAIGASTGGPPLLHRILAALPEDFGAAVLVVQHMSVGFTENFVHWLNLHSRMPVRLAAEGTVIAAGEVYVAPDGCHMEA
TPAGRIALSGAPPENGVRPSIDVLFRSVAKSYGANAAGIILSGMGKDGAVELKTLKGRGGLCIAQNRESSMVFGMPGEAI
KIDAVQHVLSPEGIINLLLAVTKKGAQGASK

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR [H]

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788192, Length=350, Percent_Identity=33.1428571428571, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789 [H]

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg [H]

EC number: =3.1.1.61 [H]

Molecular weight: Translated: 36735; Mature: 36735

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50122 CHEB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRLLVVEDSKTVQKALVAAFQADPELQVIGVAESGEEAVEAAARLKPDLITMDLHLSGM
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECCC
NGLDATRAIMSTSPVPIVVVSGKIDTRDSDLLFRFMEAGVLMVLPKPAPVGTPGYAESVA
CCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHH
SLIHHIKLMSEIKVVRRVFAPGALGQWPKSPLKEPLAPVKVVAIGASTGGPPLLHRILAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
LPEDFGAAVLVVQHMSVGFTENFVHWLNLHSRMPVRLAAEGTVIAAGEVYVAPDGCHMEA
CCCCCCHHEEEEEHHHCCCHHHHHHHHHHCCCCCEEEECCCCEEEECEEEECCCCCEEEC
TPAGRIALSGAPPENGVRPSIDVLFRSVAKSYGANAAGIILSGMGKDGAVELKTLKGRGG
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCC
LCIAQNRESSMVFGMPGEAIKIDAVQHVLSPEGIINLLLAVTKKGAQGASK
EEEEECCCCCEEEECCCCEEEHHHHHHHHCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIRLLVVEDSKTVQKALVAAFQADPELQVIGVAESGEEAVEAAARLKPDLITMDLHLSGM
CEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEEEECCC
NGLDATRAIMSTSPVPIVVVSGKIDTRDSDLLFRFMEAGVLMVLPKPAPVGTPGYAESVA
CCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHH
SLIHHIKLMSEIKVVRRVFAPGALGQWPKSPLKEPLAPVKVVAIGASTGGPPLLHRILAA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHH
LPEDFGAAVLVVQHMSVGFTENFVHWLNLHSRMPVRLAAEGTVIAAGEVYVAPDGCHMEA
CCCCCCHHEEEEEHHHCCCHHHHHHHHHHCCCCCEEEECCCCEEEECEEEECCCCCEEEC
TPAGRIALSGAPPENGVRPSIDVLFRSVAKSYGANAAGIILSGMGKDGAVELKTLKGRGG
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCC
LCIAQNRESSMVFGMPGEAIKIDAVQHVLSPEGIINLLLAVTKKGAQGASK
EEEEECCCCCEEEECCCCEEEHHHHHHHHCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA