Click here to switch to the map view.

The map label for this gene is trpD

Identifier: 197118339

GI number: 197118339

Start: 2260100

End: 2261158

Strand: Direct

Name: trpD

Synonym: Gbem_1956

Alternate gene names: 197118339

Gene position: 2260100-2261158 (Clockwise)

Preceding gene: 197118338

Following gene: 197118340

Centisome position: 48.97

GC content: 66.1

Gene sequence:

>1059_bases
ATGATTCGCAAGGCAATCGCACGTGTTGTGGAACGGCAGGATCTTTCCGAAGCAGAGATGATCGAGGTCATGGACCAGGT
GATGTCCGGCGGCGCCACCCCGGCGCAGATCGCCTCCTTCATCACCGCCCTCAGGATGAAGGGGGAGACGGTTGACGAGA
TCACCGGCGCCGCGCGCGTCATGCGCGACCGGGCGCTTCCCATCCGGGTCGGCAAGAGCGTGCTCGGCATCGACCGCGAC
GACATCAACCTCGACCGCGAGACCATCCTCGACACCTGCGGCACCGGCGGCAGCGGCACCAACAGCTTCAACATCTCCAC
CACCGTAGCCTTCATCGTATCCGCCTGCGGCGTCAAGGTCGCCAAGCACGGCAACCGCGCGGTCTCCTCTTCCTGCGGCT
CGGCCGACGTCCTGGAGGCGTTGGGGGTGAACCTCGACGTCACCCCCGATGTGGTCGAGCGGAGCATCGCCCAGATCGGC
ATCGGCTTTCTCTTCGCCCCGGCGCTTCACGGCGCCATGAAGCACGCCATCGGCCCCAGGCGCGAGATCGGCATCCGTAC
CATCTTCAACATATTGGGCCCCTTGACCAACCCCGCCGGCGCCGACTGCCAGGTGCTCGGCGTCTACCGCGAGGACCTGG
TGGAGAAGCTCGCGCAGGTCTTGAAGAAACTCGGCTGCCGCAGCGGCTTCGTGGTGCATGGCTGCGACGGCATGGACGAG
ATCACCCTGACCGGCGAGAGCACCGTGGCCGAGATCACCGCCGACGGCGTGAAGCTCTACAAGGTAACCCCGGAACAGTT
CGGCCTGGAGCGCGCTCCGCTTGCCGAACTCCACGGCGGCGATGCGCTGGGAAACGCGGTGATCGTGAGGGACATCCTCT
CCGGCAAGGACGGCGCCAAGAGGCGCATCGTGCTTTTGAACGCGGGGTACGCGCTGGTCGCCACCGGGAAGGCGAAGGAT
GTCGCCGAGGGGATACGTCTCGCCGCCGAGACCATTGACTCCGGCGCGGCGATGAAGCAGCTGGAGCGGCTGGTCGCGCT
TACCAACGAGGCGGAGTAG

Upstream 100 bases:

>100_bases
CGTCCCGCACCGGATCACCCCGTCTTTCGCTGTTTTCCCCAGTGCTGCCTTTCTTTTTTCTGTGGTGATGCTTTTGATCT
TTGGTTGATAAGGAGCGGCT

Downstream 100 bases:

>100_bases
ACTTCTCTCCCCCGCCGAGGCGGAATAGACTTCTCTCCCCCTCCCTTGACGGGAGGGGTCGGGGGGTGGGTGAAGCTGCC
AACGAAGTCGTATCTGGCGC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MIRKAIARVVERQDLSEAEMIEVMDQVMSGGATPAQIASFITALRMKGETVDEITGAARVMRDRALPIRVGKSVLGIDRD
DINLDRETILDTCGTGGSGTNSFNISTTVAFIVSACGVKVAKHGNRAVSSSCGSADVLEALGVNLDVTPDVVERSIAQIG
IGFLFAPALHGAMKHAIGPRREIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEKLAQVLKKLGCRSGFVVHGCDGMDE
ITLTGESTVAEITADGVKLYKVTPEQFGLERAPLAELHGGDALGNAVIVRDILSGKDGAKRRIVLLNAGYALVATGKAKD
VAEGIRLAAETIDSGAAMKQLERLVALTNEAE

Sequences:

>Translated_352_residues
MIRKAIARVVERQDLSEAEMIEVMDQVMSGGATPAQIASFITALRMKGETVDEITGAARVMRDRALPIRVGKSVLGIDRD
DINLDRETILDTCGTGGSGTNSFNISTTVAFIVSACGVKVAKHGNRAVSSSCGSADVLEALGVNLDVTPDVVERSIAQIG
IGFLFAPALHGAMKHAIGPRREIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEKLAQVLKKLGCRSGFVVHGCDGMDE
ITLTGESTVAEITADGVKLYKVTPEQFGLERAPLAELHGGDALGNAVIVRDILSGKDGAKRRIVLLNAGYALVATGKAKD
VAEGIRLAAETIDSGAAMKQLERLVALTNEAE
>Mature_352_residues
MIRKAIARVVERQDLSEAEMIEVMDQVMSGGATPAQIASFITALRMKGETVDEITGAARVMRDRALPIRVGKSVLGIDRD
DINLDRETILDTCGTGGSGTNSFNISTTVAFIVSACGVKVAKHGNRAVSSSCGSADVLEALGVNLDVTPDVVERSIAQIG
IGFLFAPALHGAMKHAIGPRREIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEKLAQVLKKLGCRSGFVVHGCDGMDE
ITLTGESTVAEITADGVKLYKVTPEQFGLERAPLAELHGGDALGNAVIVRDILSGKDGAKRRIVLLNAGYALVATGKAKD
VAEGIRLAAETIDSGAAMKQLERLVALTNEAE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=345, Percent_Identity=35.6521739130435, Blast_Score=204, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320561, Length=336, Percent_Identity=32.7380952380952, Blast_Score=149, Evalue=8e-37,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_GEOBB (B5EBU6)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002138766.1
- ProteinModelPortal:   B5EBU6
- SMR:   B5EBU6
- GeneID:   6781946
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_1956
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 37060; Mature: 37060

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKAIARVVERQDLSEAEMIEVMDQVMSGGATPAQIASFITALRMKGETVDEITGAARV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MRDRALPIRVGKSVLGIDRDDINLDRETILDTCGTGGSGTNSFNISTTVAFIVSACGVKV
HHHCCCCHHHCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHH
AKHGNRAVSSSCGSADVLEALGVNLDVTPDVVERSIAQIGIGFLFAPALHGAMKHAIGPR
HHCCCHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
REIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEKLAQVLKKLGCRSGFVVHGCDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCC
ITLTGESTVAEITADGVKLYKVTPEQFGLERAPLAELHGGDALGNAVIVRDILSGKDGAK
EEECCCCHHHHEECCCEEEEEECHHHHCCCCCCHHHHCCCCHHCCHHHHHHHHCCCCCCC
RRIVLLNAGYALVATGKAKDVAEGIRLAAETIDSGAAMKQLERLVALTNEAE
EEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRKAIARVVERQDLSEAEMIEVMDQVMSGGATPAQIASFITALRMKGETVDEITGAARV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
MRDRALPIRVGKSVLGIDRDDINLDRETILDTCGTGGSGTNSFNISTTVAFIVSACGVKV
HHHCCCCHHHCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHH
AKHGNRAVSSSCGSADVLEALGVNLDVTPDVVERSIAQIGIGFLFAPALHGAMKHAIGPR
HHCCCHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
REIGIRTIFNILGPLTNPAGADCQVLGVYREDLVEKLAQVLKKLGCRSGFVVHGCDGMDE
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCC
ITLTGESTVAEITADGVKLYKVTPEQFGLERAPLAELHGGDALGNAVIVRDILSGKDGAK
EEECCCCHHHHEECCCEEEEEECHHHHCCCCCCHHHHCCCCHHCCHHHHHHHHCCCCCCC
RRIVLLNAGYALVATGKAKDVAEGIRLAAETIDSGAAMKQLERLVALTNEAE
EEEEEEECCEEEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA