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The map label for this gene is yleA [C]

Identifier: 197118030

GI number: 197118030

Start: 1907730

End: 1909019

Strand: Reverse

Name: yleA [C]

Synonym: Gbem_1643

Alternate gene names: 197118030

Gene position: 1909019-1907730 (Counterclockwise)

Preceding gene: 197118031

Following gene: 197118019

Centisome position: 41.36

GC content: 64.5

Gene sequence:

>1290_bases
ATGAGTAAGACCATCGCCATAACCACCCTCGGTTGCAAGATCAACCAGTTCGAATCGGCCGCCATGACCCAGGCGCTGGA
GCAAAACGGCTACAGCATGGTCCCCTTCTCGGATAAGGCCGACATCTACGTCATCAACAGCTGCACCGTGACGGCGAAGA
CCGACGCGGAATCGCGCCGGCTGATCCGGCGCGCCACCCGCCTGAACCCGGAAGCGCGCGTGGTCGTCACCGGCTGCTAC
GCCCAAATGAACGCGGAGGAACTGCTGAAGCTGGCCGGGGTCAACCTGATCCTCGGCAACAGCGAGAAGAAGGACATCGT
CGGTTTCCTGGAAGGGATGGACGACCAGCCGCGGGCCGTGGTGAGCGACATCTCGCTGGAAAAGACCGGGGATACGGCGC
CGCTGGAGACCTTCGCCGAGCACACCCGCGCCTTTCTGCAGGTGCAAAACGGCTGCGACGCGCGCTGCGCCTACTGCATC
GTCCCCTACGCCAGGGGGGCCAGCAGGAGCGTGGCCGTCCAGGAGGCCCTAGACGGCATGGCCGCCTTCGCCGCCCAGGG
TTTCCAGGAGATCGTCTTGACCGGGATCCACCTGGGCGCCTACGGACTCGACCTGGCCCCCGCCACAGACCTCCTCGGCC
TGATGCAGAAGGCCCAGGAACAAGGTGTGGTGCGGCGCCTGAGGATCGGATCGGTAGAGCCGACCGAGGTGTCAAAGCAA
CTGATCGACTTCATGGCCCGCTCGCCCATGGTCTGCCCGCACCTCCACCTGCCGCTGCAAAGCGGCTCGGACAGCGTCCT
CTCCCGCATGAACCGCGGCTACGACACCGCCCTTTTCCGCGAGGTGGTGCAGTCGCTCGCGTCGGCGATGCCGGAGGTCT
GCATCGGTTCCGACGTGATCGCCGGGTTCCCCGGGGAAAGCGACCAGGAGTTCGACGAGACCTACCGCTTCATCGACTCG
CTACCGCTCGCGTACCTGCATGTGTTCCCCTTCTCGCAGCGCCCCGGCACGCCGGCGGCGACCATGACGCCGCAGGTGCA
TCCCAAGGTGATCAAGGAGCGGGCCGAGGCGCTGAGGGTACTGTCGGAGCGGAAGAAATCGGATTATGCGGCGGGATTTG
TGGGTCGCGAGCTTCGGGTCCTGGTGCAAAAGGGGGAGAAGGGACTCTCCAGAAACTACCTGACCGTGCTGATCGAAGAA
AGCAAGGGGCTGGTGAACCGCGAGGTAACGGTACAGGTGACCGGGGCCAAAGATGGGGAACTGGTTGGCCGGGTGCTTAA
GGAAAGCTAG

Upstream 100 bases:

>100_bases
TGTTAAATATGTTTTAAGGTTTTCTTTGCGTCTTTGCGTCTTTGCGTGAGATCGATTTTCGTCTTTGCGTCTTTGCGGCT
TTGCGTGAGAAAAAGGATTT

Downstream 100 bases:

>100_bases
ACGCTGAAGGTGAAGGTGGCGCCCTTCCCCAGTTCGGCCTGCGCCTCGATCTTCCCTCCATGGCGGGTGATTATCCTCCT
GGCGATGGCAAGCCCGATCC

Product: MiaB-like tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSKTIAITTLGCKINQFESAAMTQALEQNGYSMVPFSDKADIYVINSCTVTAKTDAESRRLIRRATRLNPEARVVVTGCY
AQMNAEELLKLAGVNLILGNSEKKDIVGFLEGMDDQPRAVVSDISLEKTGDTAPLETFAEHTRAFLQVQNGCDARCAYCI
VPYARGASRSVAVQEALDGMAAFAAQGFQEIVLTGIHLGAYGLDLAPATDLLGLMQKAQEQGVVRRLRIGSVEPTEVSKQ
LIDFMARSPMVCPHLHLPLQSGSDSVLSRMNRGYDTALFREVVQSLASAMPEVCIGSDVIAGFPGESDQEFDETYRFIDS
LPLAYLHVFPFSQRPGTPAATMTPQVHPKVIKERAEALRVLSERKKSDYAAGFVGRELRVLVQKGEKGLSRNYLTVLIEE
SKGLVNREVTVQVTGAKDGELVGRVLKES

Sequences:

>Translated_429_residues
MSKTIAITTLGCKINQFESAAMTQALEQNGYSMVPFSDKADIYVINSCTVTAKTDAESRRLIRRATRLNPEARVVVTGCY
AQMNAEELLKLAGVNLILGNSEKKDIVGFLEGMDDQPRAVVSDISLEKTGDTAPLETFAEHTRAFLQVQNGCDARCAYCI
VPYARGASRSVAVQEALDGMAAFAAQGFQEIVLTGIHLGAYGLDLAPATDLLGLMQKAQEQGVVRRLRIGSVEPTEVSKQ
LIDFMARSPMVCPHLHLPLQSGSDSVLSRMNRGYDTALFREVVQSLASAMPEVCIGSDVIAGFPGESDQEFDETYRFIDS
LPLAYLHVFPFSQRPGTPAATMTPQVHPKVIKERAEALRVLSERKKSDYAAGFVGRELRVLVQKGEKGLSRNYLTVLIEE
SKGLVNREVTVQVTGAKDGELVGRVLKES
>Mature_428_residues
SKTIAITTLGCKINQFESAAMTQALEQNGYSMVPFSDKADIYVINSCTVTAKTDAESRRLIRRATRLNPEARVVVTGCYA
QMNAEELLKLAGVNLILGNSEKKDIVGFLEGMDDQPRAVVSDISLEKTGDTAPLETFAEHTRAFLQVQNGCDARCAYCIV
PYARGASRSVAVQEALDGMAAFAAQGFQEIVLTGIHLGAYGLDLAPATDLLGLMQKAQEQGVVRRLRIGSVEPTEVSKQL
IDFMARSPMVCPHLHLPLQSGSDSVLSRMNRGYDTALFREVVQSLASAMPEVCIGSDVIAGFPGESDQEFDETYRFIDSL
PLAYLHVFPFSQRPGTPAATMTPQVHPKVIKERAEALRVLSERKKSDYAAGFVGRELRVLVQKGEKGLSRNYLTVLIEES
KGLVNREVTVQVTGAKDGELVGRVLKES

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=436, Percent_Identity=30.045871559633, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI28872784, Length=434, Percent_Identity=26.2672811059908, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI28872782, Length=434, Percent_Identity=26.2672811059908, Blast_Score=146, Evalue=3e-35,
Organism=Escherichia coli, GI1786882, Length=449, Percent_Identity=30.0668151447661, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787057, Length=392, Percent_Identity=26.2755102040816, Blast_Score=126, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17553146, Length=382, Percent_Identity=26.9633507853403, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71996771, Length=289, Percent_Identity=27.681660899654, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356207, Length=371, Percent_Identity=28.0323450134771, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19922432, Length=460, Percent_Identity=28.9130434782609, Blast_Score=147, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46768; Mature: 46637

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTIAITTLGCKINQFESAAMTQALEQNGYSMVPFSDKADIYVINSCTVTAKTDAESRR
CCCEEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEEEEECCCHHHHH
LIRRATRLNPEARVVVTGCYAQMNAEELLKLAGVNLILGNSEKKDIVGFLEGMDDQPRAV
HHHHHHHCCCCCEEEEEECHHHCCHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCHHH
VSDISLEKTGDTAPLETFAEHTRAFLQVQNGCDARCAYCIVPYARGASRSVAVQEALDGM
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
AAFAAQGFQEIVLTGIHLGAYGLDLAPATDLLGLMQKAQEQGVVRRLRIGSVEPTEVSKQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIDFMARSPMVCPHLHLPLQSGSDSVLSRMNRGYDTALFREVVQSLASAMPEVCIGSDVI
HHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCCE
AGFPGESDQEFDETYRFIDSLPLAYLHVFPFSQRPGTPAATMTPQVHPKVIKERAEALRV
ECCCCCCCHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LSERKKSDYAAGFVGRELRVLVQKGEKGLSRNYLTVLIEESKGLVNREVTVQVTGAKDGE
HHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCHH
LVGRVLKES
HHHHHHHCC
>Mature Secondary Structure 
SKTIAITTLGCKINQFESAAMTQALEQNGYSMVPFSDKADIYVINSCTVTAKTDAESRR
CCEEEEEEECCCCCHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEEEEECCCHHHHH
LIRRATRLNPEARVVVTGCYAQMNAEELLKLAGVNLILGNSEKKDIVGFLEGMDDQPRAV
HHHHHHHCCCCCEEEEEECHHHCCHHHHHHHHCCEEEECCCCCHHHHHHHHCCCCCCHHH
VSDISLEKTGDTAPLETFAEHTRAFLQVQNGCDARCAYCIVPYARGASRSVAVQEALDGM
HHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
AAFAAQGFQEIVLTGIHLGAYGLDLAPATDLLGLMQKAQEQGVVRRLRIGSVEPTEVSKQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LIDFMARSPMVCPHLHLPLQSGSDSVLSRMNRGYDTALFREVVQSLASAMPEVCIGSDVI
HHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCCE
AGFPGESDQEFDETYRFIDSLPLAYLHVFPFSQRPGTPAATMTPQVHPKVIKERAEALRV
ECCCCCCCHHHHHHHHHHHHCCHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
LSERKKSDYAAGFVGRELRVLVQKGEKGLSRNYLTVLIEESKGLVNREVTVQVTGAKDGE
HHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCHH
LVGRVLKES
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]