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The map label for this gene is wzxE [C]

Identifier: 197117999

GI number: 197117999

Start: 1870175

End: 1871662

Strand: Direct

Name: wzxE [C]

Synonym: Gbem_1612

Alternate gene names: 197117999

Gene position: 1870175-1871662 (Clockwise)

Preceding gene: 197117998

Following gene: 197118000

Centisome position: 40.52

GC content: 60.08

Gene sequence:

>1488_bases
ATGGCTGCTGAGACTGGGACTACAGCTGAAAAAAGGGGCTCCATCGGGCACATACTGAAGGCGTCCGCGGTCATGGGGAG
TTCGGCTGTGGTCCAGATCGCCACAGGAATCCTGAAGAACAAGGTGGTGGCCCTGCTTCTGGGCCCTAGTGGGGTTGGCG
CCTTCGCCCTGTTGCAATCCGTTCAGGCCACCGCTTCCACCGTTGCCGGTCTCGGGCTTAACTCAAGCGGCGTGCGCCAG
ATATCTGATGCCGAGGCAAAGGGGGGGGAGGGCGGCGTTGCGCTCTGCTACCTAGTCCTGAGGCGTCTTGCCATGGCGGC
CGCAATCATCGGAGCGTTACTCATGCTCCTGCTTAGGACACCGATATCTAAGCTAGCGGGTTACGGAGGTCCCTCCGGCG
CGACCACCATCGCCATTCTGGGAATCGGTGTATGGGCTACTACCGTTTCCGGCGCTCAGACCGCGCTCCTCAACGGGTTG
CGCCGCATAGGAGACCTTGCCCGTGTCAACGGTATGGGCGCCATCATCGGCATGCTCGTTACCTTGGCAGCGCTGTGGCT
CTTGAAAGAATCAGGCATCGTCGTCGCTGTCGTAGGCAGCTCGCTAGCCACGCTGCTGGTTTCCTGGTTTCTAAGCCGCA
AGATCGAACTCCCGAACAGGGCGGTGCGCCGCGAAGAATTCCTGGCCCATTCGGAAAAGCTATTACGCCTCGGCGTAGTC
TTCATGGGGTCCGCCGTCCTGACCGTCGGGTGCCAGTTCGTCGTCCGAGCGATTCTCGCTCGAAAACTTGGCATTGAGGC
GACTGGACAGTTCCACGCTGCTTGGAACATATCCATGCTGTACGTGAGCTTCGCGCTGAACGCAATGGGGACGGACTTCT
ACCCGAGATTGACCGCCGTTGCGGACGACCACGCGCAGTCGCGCAGGATGGTGAACGAGCAGGGGGAGGTGGCGATCCTT
CTCACCGCCCCGGTCATACTAGGTATGTTGACCTTCGCCCCCTTTGTAGTGGCTGCTCTTTATTCGAGCGCCTTCGGCGC
CACGTCGGAGATCCTGCGCTGGCAGGTACTCGGCGACCTTTTCAAGATCGTGGCGTGGCCGATGGGGTTCGTCATGCTCG
CCCAAGGGAGCTGCCGCGCCTTCCTCGTTGCCGAACTGTTCTGGAACGGCCTGTACCTGGCCCTGGTGGCTGCGGGCATC
CCGTACTTTGGCGTCAGCGCGACAGGCATATCGTTCTTCATCTCGTACCTGTTGCTGTGCCTGCTGAATGGCTTCTTTGC
CTACCGGCTTATCAAGTTCGTTCCCAGCAGGGCCAACGTTGCCAACATCTCGGTACTGTTCCTGCTGGCGTTGCTAGTCA
CCTTCCTGGTCAAAGACGGCTCTTCCGCCGGTTACCTAGCTGGCACCTTGATCACGACCGGCGTCGGAGCATCCTCATTG
CTGCGCATAACCCGCTCGCTAGGAAGGAATCCCTTCAGCAGAAAGTAA

Upstream 100 bases:

>100_bases
GGCGACAACTCGGTCATCGCCTCGCAGTCGGTAGTGACGCGCGACATTCCCCCAAACTCTGTGGCCGGGGGCAATCCCGC
CAAAGTACTTAGGACCCTCG

Downstream 100 bases:

>100_bases
GGACGCTGACGTCCAAACACGGAGCAAATGTGGCTATAGACTTAAATCTCAAAATCTCAGTGGTGATACCGACATACGGG
CGGGCGCAGATGGTGAAACA

Product: lipopolysaccharide biosynthesis protein

Products: NA

Alternate protein names: Lipopolysaccharide Biosynthesis Protein; Flippase; Transmembrane Polysaccharide Biosynthesis Protein; WzxB Protein; Flippase Involved In Lipopolysaccharide Biosynthesis

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MAAETGTTAEKRGSIGHILKASAVMGSSAVVQIATGILKNKVVALLLGPSGVGAFALLQSVQATASTVAGLGLNSSGVRQ
ISDAEAKGGEGGVALCYLVLRRLAMAAAIIGALLMLLLRTPISKLAGYGGPSGATTIAILGIGVWATTVSGAQTALLNGL
RRIGDLARVNGMGAIIGMLVTLAALWLLKESGIVVAVVGSSLATLLVSWFLSRKIELPNRAVRREEFLAHSEKLLRLGVV
FMGSAVLTVGCQFVVRAILARKLGIEATGQFHAAWNISMLYVSFALNAMGTDFYPRLTAVADDHAQSRRMVNEQGEVAIL
LTAPVILGMLTFAPFVVAALYSSAFGATSEILRWQVLGDLFKIVAWPMGFVMLAQGSCRAFLVAELFWNGLYLALVAAGI
PYFGVSATGISFFISYLLLCLLNGFFAYRLIKFVPSRANVANISVLFLLALLVTFLVKDGSSAGYLAGTLITTGVGASSL
LRITRSLGRNPFSRK

Sequences:

>Translated_495_residues
MAAETGTTAEKRGSIGHILKASAVMGSSAVVQIATGILKNKVVALLLGPSGVGAFALLQSVQATASTVAGLGLNSSGVRQ
ISDAEAKGGEGGVALCYLVLRRLAMAAAIIGALLMLLLRTPISKLAGYGGPSGATTIAILGIGVWATTVSGAQTALLNGL
RRIGDLARVNGMGAIIGMLVTLAALWLLKESGIVVAVVGSSLATLLVSWFLSRKIELPNRAVRREEFLAHSEKLLRLGVV
FMGSAVLTVGCQFVVRAILARKLGIEATGQFHAAWNISMLYVSFALNAMGTDFYPRLTAVADDHAQSRRMVNEQGEVAIL
LTAPVILGMLTFAPFVVAALYSSAFGATSEILRWQVLGDLFKIVAWPMGFVMLAQGSCRAFLVAELFWNGLYLALVAAGI
PYFGVSATGISFFISYLLLCLLNGFFAYRLIKFVPSRANVANISVLFLLALLVTFLVKDGSSAGYLAGTLITTGVGASSL
LRITRSLGRNPFSRK
>Mature_494_residues
AAETGTTAEKRGSIGHILKASAVMGSSAVVQIATGILKNKVVALLLGPSGVGAFALLQSVQATASTVAGLGLNSSGVRQI
SDAEAKGGEGGVALCYLVLRRLAMAAAIIGALLMLLLRTPISKLAGYGGPSGATTIAILGIGVWATTVSGAQTALLNGLR
RIGDLARVNGMGAIIGMLVTLAALWLLKESGIVVAVVGSSLATLLVSWFLSRKIELPNRAVRREEFLAHSEKLLRLGVVF
MGSAVLTVGCQFVVRAILARKLGIEATGQFHAAWNISMLYVSFALNAMGTDFYPRLTAVADDHAQSRRMVNEQGEVAILL
TAPVILGMLTFAPFVVAALYSSAFGATSEILRWQVLGDLFKIVAWPMGFVMLAQGSCRAFLVAELFWNGLYLALVAAGIP
YFGVSATGISFFISYLLLCLLNGFFAYRLIKFVPSRANVANISVLFLLALLVTFLVKDGSSAGYLAGTLITTGVGASSLL
RITRSLGRNPFSRK

Specific function: Synthesis of enterobacterial common antigen (ECA). [C]

COG id: COG2244

COG function: function code R; Membrane protein involved in the export of O-antigen and teichoic acid

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790227, Length=421, Percent_Identity=23.0403800475059, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51920; Mature: 51789

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAETGTTAEKRGSIGHILKASAVMGSSAVVQIATGILKNKVVALLLGPSGVGAFALLQS
CCCCCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
VQATASTVAGLGLNSSGVRQISDAEAKGGEGGVALCYLVLRRLAMAAAIIGALLMLLLRT
HHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PISKLAGYGGPSGATTIAILGIGVWATTVSGAQTALLNGLRRIGDLARVNGMGAIIGMLV
CHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TLAALWLLKESGIVVAVVGSSLATLLVSWFLSRKIELPNRAVRREEFLAHSEKLLRLGVV
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FMGSAVLTVGCQFVVRAILARKLGIEATGQFHAAWNISMLYVSFALNAMGTDFYPRLTAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHH
ADDHAQSRRMVNEQGEVAILLTAPVILGMLTFAPFVVAALYSSAFGATSEILRWQVLGDL
HHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FKIVAWPMGFVMLAQGSCRAFLVAELFWNGLYLALVAAGIPYFGVSATGISFFISYLLLC
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LLNGFFAYRLIKFVPSRANVANISVLFLLALLVTFLVKDGSSAGYLAGTLITTGVGASSL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHH
LRITRSLGRNPFSRK
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
AAETGTTAEKRGSIGHILKASAVMGSSAVVQIATGILKNKVVALLLGPSGVGAFALLQS
CCCCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHH
VQATASTVAGLGLNSSGVRQISDAEAKGGEGGVALCYLVLRRLAMAAAIIGALLMLLLRT
HHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PISKLAGYGGPSGATTIAILGIGVWATTVSGAQTALLNGLRRIGDLARVNGMGAIIGMLV
CHHHHCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TLAALWLLKESGIVVAVVGSSLATLLVSWFLSRKIELPNRAVRREEFLAHSEKLLRLGVV
HHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FMGSAVLTVGCQFVVRAILARKLGIEATGQFHAAWNISMLYVSFALNAMGTDFYPRLTAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHH
ADDHAQSRRMVNEQGEVAILLTAPVILGMLTFAPFVVAALYSSAFGATSEILRWQVLGDL
HHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
FKIVAWPMGFVMLAQGSCRAFLVAELFWNGLYLALVAAGIPYFGVSATGISFFISYLLLC
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LLNGFFAYRLIKFVPSRANVANISVLFLLALLVTFLVKDGSSAGYLAGTLITTGVGASSL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHH
LRITRSLGRNPFSRK
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA