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The map label for this gene is sucC-2 [H]

Identifier: 197117851

GI number: 197117851

Start: 1695068

End: 1696246

Strand: Direct

Name: sucC-2 [H]

Synonym: Gbem_1464

Alternate gene names: 197117851

Gene position: 1695068-1696246 (Clockwise)

Preceding gene: 197117850

Following gene: 197117852

Centisome position: 36.73

GC content: 62.26

Gene sequence:

>1179_bases
ATGAACATTCACGAGTATCAGGCAAAAGCGATATTGAGAAAATTCGGCGTGCCGGTCCCGGACGGGCATGTCTGCTATAA
CGGCGCCAGCGCCCGCGAGTGGGCCAAGAGGCTCGGCGAAGGACCTTGGGTGGTGAAGGCGCAGATCCATGCCGGCGGCC
GCGGCAAAGGCGGCGGCGTGAAGCTCGCCAAGAGCGCAAGCGAAGTGCAGTTGATCGCCCGCGACATGCTGGGCATGACC
TTGAGGACTCACCAGACCGGACCGGAAGGGAAGGTGGTACACCGGGTCCTGGTCGAAAACGGCTGCAACATCGCCCGCGA
ACTTTATGTAAGCCTCGTCGTCGACCGCAACAGCTCCAAAGTCGCGGTGATGGCATCCACCGAAGGGGGGATGGACATCG
AGGAAGTGGCGGCCAAGACCCCGGAGAAGATCTTCACCGAAACCATCGATCCGCTGGTGGGGCTGACCCAGTTCCAGGGC
CGCAAGATCGCTTTCAGCTTGGGGCTCGAAGGGAAGCAGGTGGGGAAAGCAGTCAAGATGTTGGAGGCGCTCTACACCAC
CTTCATCGCCTGCGACTGCGCCATGCTGGAAGTGAACCCGCTGGTGGTCACCGCGGAGGGGGAACTCCTGGCGCTCGACG
CCAAGTTCGGCTTCGACGACAATGCGCTCTTCCGCCACCTGCAGATAGGCGACATGCGCGACTTCGACGAGGAAGACCCC
AACGAGATCGAGGCGTCGCAGCACGACCTCTCCTACATCTCCCTTACCGGCAACATCGGCTGCCTCGTTAACGGCGCAGG
CCTCGCCATGGCCACCATGGACATCATCAAGCACTACGGGGGAGATCCCGCCAACTTCCTGGACGTAGGGGGCGGGGCCA
CCATCGAGCGCGTCACCGAGGCCTTCAAAATCATCCTCTCCGACCGTAACGTGGAAGGGATCCTGGTCAACATCTTCGGC
GGCATCATGAAGTGCGACGTCATCGCCACCGGCGTCATCCAGGCGGCGCGCCAGGTCGCCCTCAAGGTACCCCTGGTGGT
CCGGCTGGAAGGGACCAACGTGGAAAAAGGCAAAGAGCTCCTGGCCCAAAGCGGGCTCGACATAGTCGCCGCCGACGGGA
TGGCCGACGCCGCCCAGAAAATCGTGATGGCCGTTTCTGCCAAAGGGGGGAGAGCATGA

Upstream 100 bases:

>100_bases
CTTTAATGCACTTCAGAAAAGAGCCGGTCCATCCGCCGGTTACCCGCTCCAGCAATAAGAGAGAGCGCACCGCAGGATCA
CCCGGCCTTGGAGGATACCG

Downstream 100 bases:

>100_bases
GCATCTTAGTCGACAAGAACACCAAGGTCATCACCCAGGGCATCACCGGTGCCACCGGTCTCTTCCACGCGCAGGGCGCG
CGCGAGTACGGCACCCAGAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNIHEYQAKAILRKFGVPVPDGHVCYNGASAREWAKRLGEGPWVVKAQIHAGGRGKGGGVKLAKSASEVQLIARDMLGMT
LRTHQTGPEGKVVHRVLVENGCNIARELYVSLVVDRNSSKVAVMASTEGGMDIEEVAAKTPEKIFTETIDPLVGLTQFQG
RKIAFSLGLEGKQVGKAVKMLEALYTTFIACDCAMLEVNPLVVTAEGELLALDAKFGFDDNALFRHLQIGDMRDFDEEDP
NEIEASQHDLSYISLTGNIGCLVNGAGLAMATMDIIKHYGGDPANFLDVGGGATIERVTEAFKIILSDRNVEGILVNIFG
GIMKCDVIATGVIQAARQVALKVPLVVRLEGTNVEKGKELLAQSGLDIVAADGMADAAQKIVMAVSAKGGRA

Sequences:

>Translated_392_residues
MNIHEYQAKAILRKFGVPVPDGHVCYNGASAREWAKRLGEGPWVVKAQIHAGGRGKGGGVKLAKSASEVQLIARDMLGMT
LRTHQTGPEGKVVHRVLVENGCNIARELYVSLVVDRNSSKVAVMASTEGGMDIEEVAAKTPEKIFTETIDPLVGLTQFQG
RKIAFSLGLEGKQVGKAVKMLEALYTTFIACDCAMLEVNPLVVTAEGELLALDAKFGFDDNALFRHLQIGDMRDFDEEDP
NEIEASQHDLSYISLTGNIGCLVNGAGLAMATMDIIKHYGGDPANFLDVGGGATIERVTEAFKIILSDRNVEGILVNIFG
GIMKCDVIATGVIQAARQVALKVPLVVRLEGTNVEKGKELLAQSGLDIVAADGMADAAQKIVMAVSAKGGRA
>Mature_392_residues
MNIHEYQAKAILRKFGVPVPDGHVCYNGASAREWAKRLGEGPWVVKAQIHAGGRGKGGGVKLAKSASEVQLIARDMLGMT
LRTHQTGPEGKVVHRVLVENGCNIARELYVSLVVDRNSSKVAVMASTEGGMDIEEVAAKTPEKIFTETIDPLVGLTQFQG
RKIAFSLGLEGKQVGKAVKMLEALYTTFIACDCAMLEVNPLVVTAEGELLALDAKFGFDDNALFRHLQIGDMRDFDEEDP
NEIEASQHDLSYISLTGNIGCLVNGAGLAMATMDIIKHYGGDPANFLDVGGGATIERVTEAFKIILSDRNVEGILVNIFG
GIMKCDVIATGVIQAARQVALKVPLVVRLEGTNVEKGKELLAQSGLDIVAADGMADAAQKIVMAVSAKGGRA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=45.7583547557841, Blast_Score=347, Evalue=8e-96,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.9973890339426, Blast_Score=332, Evalue=4e-91,
Organism=Homo sapiens, GI294862256, Length=363, Percent_Identity=47.6584022038567, Blast_Score=317, Evalue=9e-87,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=55.4123711340206, Blast_Score=429, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=47.2081218274112, Blast_Score=350, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI17567829, Length=388, Percent_Identity=46.9072164948454, Blast_Score=337, Evalue=7e-93,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=43.8775510204082, Blast_Score=346, Evalue=4e-96,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=46.1928934010152, Blast_Score=338, Evalue=3e-93,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=46.7532467532467, Blast_Score=335, Evalue=3e-92,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=46.7532467532467, Blast_Score=335, Evalue=3e-92,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=46.8911917098446, Blast_Score=333, Evalue=1e-91,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=46.8911917098446, Blast_Score=333, Evalue=1e-91,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41787; Mature: 41787

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKAILRKFGVPVPDGHVCYNGASAREWAKRLGEGPWVVKAQIHAGGRGKGGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCE
KLAKSASEVQLIARDMLGMTLRTHQTGPEGKVVHRVLVENGCNIARELYVSLVVDRNSSK
EEECCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCHHHHHEEEEEEEECCCCE
VAVMASTEGGMDIEEVAAKTPEKIFTETIDPLVGLTQFQGRKIAFSLGLEGKQVGKAVKM
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCHHHCCCCEEEEEECCCHHHHHHHHHH
LEALYTTFIACDCAMLEVNPLVVTAEGELLALDAKFGFDDNALFRHLQIGDMRDFDEEDP
HHHHHHHHHHHCEEEEEECEEEEEECCCEEEEEECCCCCCHHHEEEEECCCCCCCCCCCC
NEIEASQHDLSYISLTGNIGCLVNGAGLAMATMDIIKHYGGDPANFLDVGGGATIERVTE
CHHCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHH
AFKIILSDRNVEGILVNIFGGIMKCDVIATGVIQAARQVALKVPLVVRLEGTNVEKGKEL
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEECCEEEEEECCCCHHHHHH
LAQSGLDIVAADGMADAAQKIVMAVSAKGGRA
HHHCCCCEEEECCHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MNIHEYQAKAILRKFGVPVPDGHVCYNGASAREWAKRLGEGPWVVKAQIHAGGRGKGGGV
CCCHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCE
KLAKSASEVQLIARDMLGMTLRTHQTGPEGKVVHRVLVENGCNIARELYVSLVVDRNSSK
EEECCHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCHHHHHEEEEEEEECCCCE
VAVMASTEGGMDIEEVAAKTPEKIFTETIDPLVGLTQFQGRKIAFSLGLEGKQVGKAVKM
EEEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHCHHHCCCCEEEEEECCCHHHHHHHHHH
LEALYTTFIACDCAMLEVNPLVVTAEGELLALDAKFGFDDNALFRHLQIGDMRDFDEEDP
HHHHHHHHHHHCEEEEEECEEEEEECCCEEEEEECCCCCCHHHEEEEECCCCCCCCCCCC
NEIEASQHDLSYISLTGNIGCLVNGAGLAMATMDIIKHYGGDPANFLDVGGGATIERVTE
CHHCCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHH
AFKIILSDRNVEGILVNIFGGIMKCDVIATGVIQAARQVALKVPLVVRLEGTNVEKGKEL
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEECCEEEEEECCCCHHHHHH
LAQSGLDIVAADGMADAAQKIVMAVSAKGGRA
HHHCCCCEEEECCHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA