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The map label for this gene is bamN [H]

Identifier: 197117847

GI number: 197117847

Start: 1689687

End: 1690862

Strand: Direct

Name: bamN [H]

Synonym: Gbem_1460

Alternate gene names: 197117847

Gene position: 1689687-1690862 (Clockwise)

Preceding gene: 308535240

Following gene: 197117848

Centisome position: 36.61

GC content: 65.48

Gene sequence:

>1176_bases
ATGTCAGATGTCTATGTCATCGAATCACTGCGTACCCCGTTGGGCTCCTTCGGCGGAGCGCTGAGCGACGTAGAAGCGCC
GCGTCTCGCCGCCACCGTCATCACCGGCATCATGGAACGCACAGGGCTTCCCGCTGAAGCCATCGACGAGGTGATTGTCG
GCCAGGTTCTCTCCGGCGGCTCGGGGCAGGCTCCCGCGCGTCAGGCCATGCGCTATGCGGGGCTCCCCGACACGGTCCCC
GCCCTCACCATCAACAAGGTCTGCGGCTCGGGCCTTAAAGCCATCATGCTCGGCGCCGGTTCCATCAAGCTTGGCGACGC
CCAACTGGTGCTCGCGGGCGGCATGGAGAACATGTCACTTGCCCCCTACGCGCTCAGCAAAGGTCGCTACGGCTACCGCA
TGGGGAACGGCGAGATGCTGGACCTGCTGGTCCACGACGGCCTGACCGACCCCTACAGCGGCAAGCACATGGGGGTGATA
GCGGAGCAAAGCGCCGGCGACAACAAGCTGGACCGCACCCTCCAGGACAGCTTCGCGCTCGCCTCCTATCAGAAGGCTCA
AGCGGCTCTGAAAGACGGGATCTTCAACGACGAGATAGTCCCGGTGGTGAAGAAGACGCGCCAGGGCGAGGTGGTCGTCC
GCGAGGACGAGGAGCCGCACAAGGTCGACTTCAAGAAACTCCCGGAGCTCCGCGCCGCCTTCCAAAAGGACGGCACCATC
ACCGCGGGTAACGCCTCTACCATCAACGACGGCGCCGCCATGGCGCTTCTGGCGAGCGGCGAGGCCGTGGCCAAATACGG
GCTGAAGCCCAAAGCCCGCCTGGTCGCCTACGCCACCAACAGCGTCCATCCCGACCAGTTCGCCGAAGCCCCGGTAGGCG
CCATCGCCAAGGTCTGCGCCAAGGCCGGGCTCACTACCGACGACATCGACCTCTTCGAGATCAATGAGGCCTTCGCCGCG
GTCCCGCTCATCGCCTGCCAAAGGCTGCGCCTCGATCCGGAGCGCGTCAACGTGAACGGCGGCGCGGTGGCGCTCGGCCA
CCCGCTAGGCGCAAGCGGTGCGCGCATCACCGCCACCTTGGTGCGGGAACTTCACAAACGCAAACAACGCTACGGTCTCG
CCACCCTCTGCATAGGCGGCGGCGAGGCGGTCGCGGTAATCCTGGAAAGGGTTTAG

Upstream 100 bases:

>100_bases
CTGTTGACAGCAAAATGGTATTGTAGTACTTATTTACCAAAAGGTGGACGCCGCGCCTGATCAGACCCGGCCGAAGCGGC
TGGATTAAGAGGAGAACGAA

Downstream 100 bases:

>100_bases
GAGGGGTCATGATCAAGAAGGTCGGAGTACTCGGCGCGGGGCAGATGGGAAGCGGTATCGCACAGGTCTTGGCCCAGCGC
GAAACGGAAGTCTACCTCTA

Product: thiolase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSDVYVIESLRTPLGSFGGALSDVEAPRLAATVITGIMERTGLPAEAIDEVIVGQVLSGGSGQAPARQAMRYAGLPDTVP
ALTINKVCGSGLKAIMLGAGSIKLGDAQLVLAGGMENMSLAPYALSKGRYGYRMGNGEMLDLLVHDGLTDPYSGKHMGVI
AEQSAGDNKLDRTLQDSFALASYQKAQAALKDGIFNDEIVPVVKKTRQGEVVVREDEEPHKVDFKKLPELRAAFQKDGTI
TAGNASTINDGAAMALLASGEAVAKYGLKPKARLVAYATNSVHPDQFAEAPVGAIAKVCAKAGLTTDDIDLFEINEAFAA
VPLIACQRLRLDPERVNVNGGAVALGHPLGASGARITATLVRELHKRKQRYGLATLCIGGGEAVAVILERV

Sequences:

>Translated_391_residues
MSDVYVIESLRTPLGSFGGALSDVEAPRLAATVITGIMERTGLPAEAIDEVIVGQVLSGGSGQAPARQAMRYAGLPDTVP
ALTINKVCGSGLKAIMLGAGSIKLGDAQLVLAGGMENMSLAPYALSKGRYGYRMGNGEMLDLLVHDGLTDPYSGKHMGVI
AEQSAGDNKLDRTLQDSFALASYQKAQAALKDGIFNDEIVPVVKKTRQGEVVVREDEEPHKVDFKKLPELRAAFQKDGTI
TAGNASTINDGAAMALLASGEAVAKYGLKPKARLVAYATNSVHPDQFAEAPVGAIAKVCAKAGLTTDDIDLFEINEAFAA
VPLIACQRLRLDPERVNVNGGAVALGHPLGASGARITATLVRELHKRKQRYGLATLCIGGGEAVAVILERV
>Mature_390_residues
SDVYVIESLRTPLGSFGGALSDVEAPRLAATVITGIMERTGLPAEAIDEVIVGQVLSGGSGQAPARQAMRYAGLPDTVPA
LTINKVCGSGLKAIMLGAGSIKLGDAQLVLAGGMENMSLAPYALSKGRYGYRMGNGEMLDLLVHDGLTDPYSGKHMGVIA
EQSAGDNKLDRTLQDSFALASYQKAQAALKDGIFNDEIVPVVKKTRQGEVVVREDEEPHKVDFKKLPELRAAFQKDGTIT
AGNASTINDGAAMALLASGEAVAKYGLKPKARLVAYATNSVHPDQFAEAPVGAIAKVCAKAGLTTDDIDLFEINEAFAAV
PLIACQRLRLDPERVNVNGGAVALGHPLGASGARITATLVRELHKRKQRYGLATLCIGGGEAVAVILERV

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=45.5470737913486, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI148539872, Length=390, Percent_Identity=44.3589743589744, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI167614485, Length=388, Percent_Identity=41.2371134020619, Blast_Score=288, Evalue=7e-78,
Organism=Homo sapiens, GI4501853, Length=396, Percent_Identity=38.6363636363636, Blast_Score=235, Evalue=6e-62,
Organism=Homo sapiens, GI4504327, Length=424, Percent_Identity=31.1320754716981, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI194353979, Length=390, Percent_Identity=31.5384615384615, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI19923233, Length=387, Percent_Identity=26.0981912144703, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082165, Length=391, Percent_Identity=48.849104859335, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=48.8549618320611, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1787663, Length=402, Percent_Identity=43.0348258706468, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI48994986, Length=410, Percent_Identity=37.5609756097561, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1788683, Length=425, Percent_Identity=28.7058823529412, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25147385, Length=387, Percent_Identity=43.9276485788114, Blast_Score=328, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI133906874, Length=392, Percent_Identity=41.5816326530612, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17535921, Length=395, Percent_Identity=41.5189873417722, Blast_Score=272, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17535917, Length=398, Percent_Identity=33.1658291457286, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17551802, Length=424, Percent_Identity=31.1320754716981, Blast_Score=189, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6325229, Length=397, Percent_Identity=44.5843828715365, Blast_Score=321, Evalue=1e-88,
Organism=Saccharomyces cerevisiae, GI6322031, Length=397, Percent_Identity=37.5314861460957, Blast_Score=213, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=47.7040816326531, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24640423, Length=393, Percent_Identity=45.5470737913486, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI17648125, Length=391, Percent_Identity=42.4552429667519, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI17137578, Length=423, Percent_Identity=30.7328605200946, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40960; Mature: 40828

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVYVIESLRTPLGSFGGALSDVEAPRLAATVITGIMERTGLPAEAIDEVIVGQVLSGG
CCCEEEHHHHHCCHHHHCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
SGQAPARQAMRYAGLPDTVPALTINKVCGSGLKAIMLGAGSIKLGDAQLVLAGGMENMSL
CCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEECCCEEECCCEEEEECCCCCCCC
APYALSKGRYGYRMGNGEMLDLLVHDGLTDPYSGKHMGVIAEQSAGDNKLDRTLQDSFAL
CCCHHCCCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ASYQKAQAALKDGIFNDEIVPVVKKTRQGEVVVREDEEPHKVDFKKLPELRAAFQKDGTI
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCE
TAGNASTINDGAAMALLASGEAVAKYGLKPKARLVAYATNSVHPDQFAEAPVGAIAKVCA
ECCCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHH
KAGLTTDDIDLFEINEAFAAVPLIACQRLRLDPERVNVNGGAVALGHPLGASGARITATL
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHEECCCCEEEECCCCCCCCCHHHHHH
VRELHKRKQRYGLATLCIGGGEAVAVILERV
HHHHHHHHHHCCEEEEEECCCCEEHHHHHCC
>Mature Secondary Structure 
SDVYVIESLRTPLGSFGGALSDVEAPRLAATVITGIMERTGLPAEAIDEVIVGQVLSGG
CCEEEHHHHHCCHHHHCCCHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
SGQAPARQAMRYAGLPDTVPALTINKVCGSGLKAIMLGAGSIKLGDAQLVLAGGMENMSL
CCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEECCCEEECCCEEEEECCCCCCCC
APYALSKGRYGYRMGNGEMLDLLVHDGLTDPYSGKHMGVIAEQSAGDNKLDRTLQDSFAL
CCCHHCCCCCEEEECCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
ASYQKAQAALKDGIFNDEIVPVVKKTRQGEVVVREDEEPHKVDFKKLPELRAAFQKDGTI
HHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCE
TAGNASTINDGAAMALLASGEAVAKYGLKPKARLVAYATNSVHPDQFAEAPVGAIAKVCA
ECCCCCCCCCCCEEEEEECCHHHHHCCCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHH
KAGLTTDDIDLFEINEAFAAVPLIACQRLRLDPERVNVNGGAVALGHPLGASGARITATL
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCHHHEECCCCEEEECCCCCCCCCHHHHHH
VRELHKRKQRYGLATLCIGGGEAVAVILERV
HHHHHHHHHHCCEEEEEECCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7867955; 11075929; 11466286; 1685080 [H]