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The map label for this gene is oadA [H]

Identifier: 197117841

GI number: 197117841

Start: 1682090

End: 1684162

Strand: Direct

Name: oadA [H]

Synonym: Gbem_1454

Alternate gene names: 197117841

Gene position: 1682090-1684162 (Clockwise)

Preceding gene: 197117840

Following gene: 197117842

Centisome position: 36.45

GC content: 64.59

Gene sequence:

>2073_bases
ATGGCCAAGACAACGAAACCGTTAGGGATAACCGAAGTCGTCCTCAGGGACGCCCACCAGTCCTTGTTCGCGACCCGCCT
GCGCCTGGACGACATGCTTCCCATCGCCGCCAAGTTGGACCAGGTCGGCTACTGGTCCATCGAGATGTGGGGGGGGGCGA
CCTTCGACTCCTGCATCCGCTTCCTCGGCGAGGACCCGTGGGAGCGCCTGCGCGAGCTGAAAAAAGCGATGCCCAACACG
CCGCAGCAGATGCTGTTCCGTGGGCAGAACATCCTCGGTTACCGCCACTACGCGGACGACGTGGTCGAGAAGTTCGTGGA
ACGCTCCGCGGTGAACGGCATCGACGTCTTCCGCGTCTTCGACGCCATGAACGACCCGCGCAACCTCGACACCGCCATCA
AGGCGGTGATTAAACAGGGCAAACACGCCCAGGGGACGCTCTCCTACACGGTGAGCCCGGTCGACACCATACCCAAATGG
GTGGCGCTGGCCAAGCGCATCGAGGACATGGGGGCGCACTCGCTCTGCATCAAGGACATGGCTGGGCTCATGGCCCCCTA
CGCCGCCTACGACCTGGTCAAGGCGCTGAAAAAAGGGATCTCCATCCCGATCCACATGCAGTGCCACGCCACCACCGGCA
TGTCCACCGCGGCCTACGTGAAGGCGATCGAGGCGGGGGTCGAGAACGTCGACACCTCCATCTCCTCCATGAGCATGACC
TACGGCCATTCGCCCACCGAGACGCTCGCCGCCATCTTCGCGGACACGGACAAGGCGACCGGCCTCGACACGGTCCTTTT
GCAGGAGATCGCCGACTACTTCACCGTTGTGCGCAAGAAATACGCGAAGTTCGAAGGCTCCCTCAAGGGTGTAGATGCCC
GCATCATCACGGCGCAGGTCCCCGGCGGCATGCTCACCAACATGGAGAGCCAGCTCAAGGAGCAAAACGCGGGGCACAAG
ATGGACCTGGTCTTGGCCGAGATCCCGAAAGTCCGCGAGGACCTGGGGATGATCCCGCTGGTCACCCCGACCTCGCAGAT
CGTCGGCACCCAGGCGGTCATCAACGTCCTGACCGGCGAGCGCTACAAGTCGATGACCAAGGAAACCGCCGCCGTCCTCA
AAGGGGAATACGGCGCGACCTCGGCCCCGGTCAACAAGGAGCTGCAGCTGAAGGTTCTGGCCGGCGCCGACCCGATCACC
TGCCGCCCGGCGGACCTCCTCAACGCGGAGATGGACAAGCTCACCGAGGAGCTGCGCGGCCTCTCCAAGGAGAAGAACCT
GAAGTTCGGCGACCACGAGGTGGAGGACGTACTCACCTACGCGCTGTTCCAGCAGGTTGGCCTCAAGTTCCTGGAGCACC
GCGACAACCCCGGCATGTTCGAGCCGGTACCCACCGCCGAGGACGCGGCGCCCAAGAAGGCGGCAGCGCCCGAAATCACC
GGCGGCGACACCTATACCGTAACCGGCGGCGGCCAGACCTTCGTGGTGCAGGTCGCCAAGGCGACCGGGGCCGCAGCAGC
CGCGGCTGCCGCAGCCTCCGCAGTTGGCGGCAACGCACCGGCGCAGGCTCCCGCAGCGGCAGCCGGCAAGACCATCGTCT
CTCCCTTGGCCGGCAACGTCTGGAAGATCGAGTGCGAGCCGGGTCAGCAGGTGCAGGAAGGCGATCTGCTCCTCATCCTC
GAAGCCATGAAGATGGAGAACGAGATCTTCGCCGACCGTGACGGCGTGGTGAGCACCATCCACATCGAGGAAGGTACTGC
CGTCGACATTGGCGCCGCGCTCGTCACCATCGCCGGCGAGGGCGATGCCGCAGCCTGCGCTTGCGCTCCGGCCGCCACGG
CCGCTGCCGCCGGCCCCGCCGAGGGAGGTGTCATGGCGCCTTTGGCCGGCAACGTCTGGAAGATCGAGGTAGAGCAGGGG
CAGGCGGTACAGGCAGGCGATCTGCTTCTCATCCTCGAAGCGATGAAGATGGAGAACGAGATCTTCGCCGAAAAGGACGG
AGTCGTCAGCCGGATCATGATCCAGGAAGGAAACGCCGTAGACATCGGCCAGCTTCTGCTGACCGTGGAGTAA

Upstream 100 bases:

>100_bases
GATTTAGGGGGATTTGCCTTTTAACCCCAAGGGGATTTGCAGTTCACCAAAAACAGACACTTCATGCAGCTTAACTTCAC
GCATATATACGGAGACGAAG

Downstream 100 bases:

>100_bases
TCCTTACCGCTCCCTCCCCTGGAGGGGGAGGGTCGGGGTGGGGCGGCTGTTACTCATGGCAGCTTCCGGCCCCCCTCCCA
GCCTCCCCCCCCCGGGGGGA

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 689

Protein sequence:

>690_residues
MAKTTKPLGITEVVLRDAHQSLFATRLRLDDMLPIAAKLDQVGYWSIEMWGGATFDSCIRFLGEDPWERLRELKKAMPNT
PQQMLFRGQNILGYRHYADDVVEKFVERSAVNGIDVFRVFDAMNDPRNLDTAIKAVIKQGKHAQGTLSYTVSPVDTIPKW
VALAKRIEDMGAHSLCIKDMAGLMAPYAAYDLVKALKKGISIPIHMQCHATTGMSTAAYVKAIEAGVENVDTSISSMSMT
YGHSPTETLAAIFADTDKATGLDTVLLQEIADYFTVVRKKYAKFEGSLKGVDARIITAQVPGGMLTNMESQLKEQNAGHK
MDLVLAEIPKVREDLGMIPLVTPTSQIVGTQAVINVLTGERYKSMTKETAAVLKGEYGATSAPVNKELQLKVLAGADPIT
CRPADLLNAEMDKLTEELRGLSKEKNLKFGDHEVEDVLTYALFQQVGLKFLEHRDNPGMFEPVPTAEDAAPKKAAAPEIT
GGDTYTVTGGGQTFVVQVAKATGAAAAAAAAASAVGGNAPAQAPAAAAGKTIVSPLAGNVWKIECEPGQQVQEGDLLLIL
EAMKMENEIFADRDGVVSTIHIEEGTAVDIGAALVTIAGEGDAAACACAPAATAAAAGPAEGGVMAPLAGNVWKIEVEQG
QAVQAGDLLLILEAMKMENEIFAEKDGVVSRIMIQEGNAVDIGQLLLTVE

Sequences:

>Translated_690_residues
MAKTTKPLGITEVVLRDAHQSLFATRLRLDDMLPIAAKLDQVGYWSIEMWGGATFDSCIRFLGEDPWERLRELKKAMPNT
PQQMLFRGQNILGYRHYADDVVEKFVERSAVNGIDVFRVFDAMNDPRNLDTAIKAVIKQGKHAQGTLSYTVSPVDTIPKW
VALAKRIEDMGAHSLCIKDMAGLMAPYAAYDLVKALKKGISIPIHMQCHATTGMSTAAYVKAIEAGVENVDTSISSMSMT
YGHSPTETLAAIFADTDKATGLDTVLLQEIADYFTVVRKKYAKFEGSLKGVDARIITAQVPGGMLTNMESQLKEQNAGHK
MDLVLAEIPKVREDLGMIPLVTPTSQIVGTQAVINVLTGERYKSMTKETAAVLKGEYGATSAPVNKELQLKVLAGADPIT
CRPADLLNAEMDKLTEELRGLSKEKNLKFGDHEVEDVLTYALFQQVGLKFLEHRDNPGMFEPVPTAEDAAPKKAAAPEIT
GGDTYTVTGGGQTFVVQVAKATGAAAAAAAAASAVGGNAPAQAPAAAAGKTIVSPLAGNVWKIECEPGQQVQEGDLLLIL
EAMKMENEIFADRDGVVSTIHIEEGTAVDIGAALVTIAGEGDAAACACAPAATAAAAGPAEGGVMAPLAGNVWKIEVEQG
QAVQAGDLLLILEAMKMENEIFAEKDGVVSRIMIQEGNAVDIGQLLLTVE
>Mature_689_residues
AKTTKPLGITEVVLRDAHQSLFATRLRLDDMLPIAAKLDQVGYWSIEMWGGATFDSCIRFLGEDPWERLRELKKAMPNTP
QQMLFRGQNILGYRHYADDVVEKFVERSAVNGIDVFRVFDAMNDPRNLDTAIKAVIKQGKHAQGTLSYTVSPVDTIPKWV
ALAKRIEDMGAHSLCIKDMAGLMAPYAAYDLVKALKKGISIPIHMQCHATTGMSTAAYVKAIEAGVENVDTSISSMSMTY
GHSPTETLAAIFADTDKATGLDTVLLQEIADYFTVVRKKYAKFEGSLKGVDARIITAQVPGGMLTNMESQLKEQNAGHKM
DLVLAEIPKVREDLGMIPLVTPTSQIVGTQAVINVLTGERYKSMTKETAAVLKGEYGATSAPVNKELQLKVLAGADPITC
RPADLLNAEMDKLTEELRGLSKEKNLKFGDHEVEDVLTYALFQQVGLKFLEHRDNPGMFEPVPTAEDAAPKKAAAPEITG
GDTYTVTGGGQTFVVQVAKATGAAAAAAAAASAVGGNAPAQAPAAAAGKTIVSPLAGNVWKIECEPGQQVQEGDLLLILE
AMKMENEIFADRDGVVSTIHIEEGTAVDIGAALVTIAGEGDAAACACAPAATAAAAGPAEGGVMAPLAGNVWKIEVEQGQ
AVQAGDLLLILEAMKMENEIFAEKDGVVSRIMIQEGNAVDIGQLLLTVE

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=627, Percent_Identity=31.2599681020734, Blast_Score=239, Evalue=7e-63,
Organism=Homo sapiens, GI106049295, Length=627, Percent_Identity=31.2599681020734, Blast_Score=239, Evalue=7e-63,
Organism=Homo sapiens, GI106049292, Length=627, Percent_Identity=31.2599681020734, Blast_Score=239, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17562816, Length=639, Percent_Identity=32.5508607198748, Blast_Score=263, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6319695, Length=631, Percent_Identity=31.0618066561014, Blast_Score=270, Evalue=8e-73,
Organism=Saccharomyces cerevisiae, GI6321376, Length=633, Percent_Identity=30.4897314375987, Blast_Score=266, Evalue=8e-72,
Organism=Drosophila melanogaster, GI281363050, Length=646, Percent_Identity=31.733746130031, Blast_Score=259, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24652224, Length=646, Percent_Identity=31.733746130031, Blast_Score=259, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24652222, Length=646, Percent_Identity=31.733746130031, Blast_Score=259, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24652220, Length=646, Percent_Identity=31.733746130031, Blast_Score=259, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24652218, Length=646, Percent_Identity=31.733746130031, Blast_Score=259, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24652212, Length=646, Percent_Identity=31.733746130031, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI24652210, Length=646, Percent_Identity=31.733746130031, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI24652214, Length=646, Percent_Identity=31.733746130031, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI19921944, Length=646, Percent_Identity=31.733746130031, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI24652216, Length=646, Percent_Identity=31.733746130031, Blast_Score=258, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 73554; Mature: 73423

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTKPLGITEVVLRDAHQSLFATRLRLDDMLPIAAKLDQVGYWSIEMWGGATFDSCIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCHHHHHH
FLGEDPWERLRELKKAMPNTPQQMLFRGQNILGYRHYADDVVEKFVERSAVNGIDVFRVF
HHCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
DAMNDPRNLDTAIKAVIKQGKHAQGTLSYTVSPVDTIPKWVALAKRIEDMGAHSLCIKDM
HHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGLMAPYAAYDLVKALKKGISIPIHMQCHATTGMSTAAYVKAIEAGVENVDTSISSMSMT
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEE
YGHSPTETLAAIFADTDKATGLDTVLLQEIADYFTVVRKKYAKFEGSLKGVDARIITAQV
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
PGGMLTNMESQLKEQNAGHKMDLVLAEIPKVREDLGMIPLVTPTSQIVGTQAVINVLTGE
CCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCH
RYKSMTKETAAVLKGEYGATSAPVNKELQLKVLAGADPITCRPADLLNAEMDKLTEELRG
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
LSKEKNLKFGDHEVEDVLTYALFQQVGLKFLEHRDNPGMFEPVPTAEDAAPKKAAAPEIT
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGDTYTVTGGGQTFVVQVAKATGAAAAAAAAASAVGGNAPAQAPAAAAGKTIVSPLAGNV
CCCEEEEECCCCEEEEEEEHHCCHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHCCCCE
WKIECEPGQQVQEGDLLLILEAMKMENEIFADRDGVVSTIHIEEGTAVDIGAALVTIAGE
EEEECCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEEEECCCCEEEECEEEEEEECC
GDAAACACAPAATAAAAGPAEGGVMAPLAGNVWKIEVEQGQAVQAGDLLLILEAMKMENE
CCCCCEECCCHHHHHCCCCCCCCEECCCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHH
IFAEKDGVVSRIMIQEGNAVDIGQLLLTVE
HHHCCCCCEEEEEEECCCCEEEEEEEEECC
>Mature Secondary Structure 
AKTTKPLGITEVVLRDAHQSLFATRLRLDDMLPIAAKLDQVGYWSIEMWGGATFDSCIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCHHHHHH
FLGEDPWERLRELKKAMPNTPQQMLFRGQNILGYRHYADDVVEKFVERSAVNGIDVFRVF
HHCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCHHHHHHH
DAMNDPRNLDTAIKAVIKQGKHAQGTLSYTVSPVDTIPKWVALAKRIEDMGAHSLCIKDM
HHCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGLMAPYAAYDLVKALKKGISIPIHMQCHATTGMSTAAYVKAIEAGVENVDTSISSMSMT
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEE
YGHSPTETLAAIFADTDKATGLDTVLLQEIADYFTVVRKKYAKFEGSLKGVDARIITAQV
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEC
PGGMLTNMESQLKEQNAGHKMDLVLAEIPKVREDLGMIPLVTPTSQIVGTQAVINVLTGE
CCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHCH
RYKSMTKETAAVLKGEYGATSAPVNKELQLKVLAGADPITCRPADLLNAEMDKLTEELRG
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
LSKEKNLKFGDHEVEDVLTYALFQQVGLKFLEHRDNPGMFEPVPTAEDAAPKKAAAPEIT
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGDTYTVTGGGQTFVVQVAKATGAAAAAAAAASAVGGNAPAQAPAAAAGKTIVSPLAGNV
CCCEEEEECCCCEEEEEEEHHCCHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHCCCCE
WKIECEPGQQVQEGDLLLILEAMKMENEIFADRDGVVSTIHIEEGTAVDIGAALVTIAGE
EEEECCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCEEEEEECCCCEEEECEEEEEEECC
GDAAACACAPAATAAAAGPAEGGVMAPLAGNVWKIEVEQGQAVQAGDLLLILEAMKMENE
CCCCCEECCCHHHHHCCCCCCCCEECCCCCCEEEEEECCCCEECCCCCHHHHHHHHHHHH
IFAEKDGVVSRIMIQEGNAVDIGQLLLTVE
HHHCCCCCEEEEEEECCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]