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The map label for this gene is cat2 [H]

Identifier: 197117806

GI number: 197117806

Start: 1634946

End: 1636283

Strand: Direct

Name: cat2 [H]

Synonym: Gbem_1418

Alternate gene names: 197117806

Gene position: 1634946-1636283 (Clockwise)

Preceding gene: 197117805

Following gene: 197117807

Centisome position: 35.43

GC content: 63.3

Gene sequence:

>1338_bases
ATGGCTGCAACGATCTGGAAGGAAATCAAGAACTGGCGCGAGATCTACAACTCGCGCGTCACCACCGCCGACGAGGCGCT
CAAATCGGTCAACTCCGGGGACCGTCTCTACCTGACCGGCAACGCCTCCGTTCCCCTGCAACTTTTGGATGCGCTGGTGA
GGCGTGCGCCGGAGCTGCGCGATGTCGAGGTCTCCCAGGTGCTCACCATCTGCCCTCAGGACTACGTCTCGCCCGAGATG
CAGGGGCACGTGCGGGTCAACACCATGTTCATCAGTCCCAACGTCCGCCAGGCGGTAAACGAAGGGCGCGCCGACTTCAC
CCCGGTGCTCCTCTCCGAGTTCCCCCTGCTCTTCAAAAACGGCCATCTCCCGCTGGATGTGGCGCTTTTGAACGTCTCCT
TGCCCGATGAAAACGGTTTCTGTTCGCTGGGGGGAGAGGCCGGCCTCACCATGACGGCGGCCGAGTCGGCGCGGATCGTC
ATCGCCCAGGTGAACAAGAAGATGCCGCGCACGCTCGGGGACACCTTCTTCCACGTCTCGCGCATGACCCATATCGTCGA
GGTGGATGCGCCGCTGACAGAAAGGCACATGGCGGAGGAGGGAGACCCCGAGATCGTCGAGCAGATAGCGGGGCACATCT
CCAGCCTCATCCCCGATGGCGCCACCATGCAGCTTGGCATCGGCGCCATTCCCGACGCGGTCTTGAAGCACCTGTTCAGC
AAGAAGGACCTGGGGATCCATTCCGAACTGATCTCCGACGGCGTCATCGACCTGGTGGAGGCCGGCGTCGTCAACTGCTC
CAGGAAGACCCTGCACCCGGGCAAGATCGTCTGCGGCTTCCTCCTTGGGACCAAGCGTCTCTACGACTGGGCGCACAACA
ACCCGATGATTGAGCTGCGCCGCACCGAGTACGTGAACGACCCATTCGTGGTGGCGCAAAACGACCGCATGGTCTCGGTG
AACGCCGCCATCGAGGTCGACTTCACCGGGCAGATCTGCGCGGACAGCATCGGCCCCAGGATGTACTCGGCGGTCGGCGG
TCAGATGGATTTCGTCTACGGCGCGTCCCGCTCCAAGGGAGGCGTCGCGGTGATCACCATGCCGAGCACCTCGACCCTCA
GGGACGGATCCGTGGTCAGCAAGATCACGCCGCTTTTGAAGCACGGGGCCGGCGTGGTGACCAGCCGCAACCACGTGCGC
TACCTGGTGACCGAATACGGCGCGGCTGACCTCTACGCGAAAAGCGTCCGCCAGCGCACCCAGGCCCTGATAGGCGTCGC
CCACCCCATGTTCCGGGAGGAGCTGACCGAGAAGGCGAAGGAACTCAGGTACATCTAA

Upstream 100 bases:

>100_bases
GCGGGCTACCTGGGACGCAAGGCGGGACGAGGGTTCTACGAGTACCCGGCCAGCTGAAAAAACGTCGATAAATCGATCCA
ACCGAAATAGGAGGCCTACC

Downstream 100 bases:

>100_bases
AAACCGGACGGGCAGGTGCAGCGCCGCCTGCCCGTCCACCGCACAGCCAGCCGATACGGCCAACGCGATAAAGGAACCTC
AACCATGAAAAAGATAATCT

Product: butyryl:4-hydroxybutyrate CoA transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MAATIWKEIKNWREIYNSRVTTADEALKSVNSGDRLYLTGNASVPLQLLDALVRRAPELRDVEVSQVLTICPQDYVSPEM
QGHVRVNTMFISPNVRQAVNEGRADFTPVLLSEFPLLFKNGHLPLDVALLNVSLPDENGFCSLGGEAGLTMTAAESARIV
IAQVNKKMPRTLGDTFFHVSRMTHIVEVDAPLTERHMAEEGDPEIVEQIAGHISSLIPDGATMQLGIGAIPDAVLKHLFS
KKDLGIHSELISDGVIDLVEAGVVNCSRKTLHPGKIVCGFLLGTKRLYDWAHNNPMIELRRTEYVNDPFVVAQNDRMVSV
NAAIEVDFTGQICADSIGPRMYSAVGGQMDFVYGASRSKGGVAVITMPSTSTLRDGSVVSKITPLLKHGAGVVTSRNHVR
YLVTEYGAADLYAKSVRQRTQALIGVAHPMFREELTEKAKELRYI

Sequences:

>Translated_445_residues
MAATIWKEIKNWREIYNSRVTTADEALKSVNSGDRLYLTGNASVPLQLLDALVRRAPELRDVEVSQVLTICPQDYVSPEM
QGHVRVNTMFISPNVRQAVNEGRADFTPVLLSEFPLLFKNGHLPLDVALLNVSLPDENGFCSLGGEAGLTMTAAESARIV
IAQVNKKMPRTLGDTFFHVSRMTHIVEVDAPLTERHMAEEGDPEIVEQIAGHISSLIPDGATMQLGIGAIPDAVLKHLFS
KKDLGIHSELISDGVIDLVEAGVVNCSRKTLHPGKIVCGFLLGTKRLYDWAHNNPMIELRRTEYVNDPFVVAQNDRMVSV
NAAIEVDFTGQICADSIGPRMYSAVGGQMDFVYGASRSKGGVAVITMPSTSTLRDGSVVSKITPLLKHGAGVVTSRNHVR
YLVTEYGAADLYAKSVRQRTQALIGVAHPMFREELTEKAKELRYI
>Mature_444_residues
AATIWKEIKNWREIYNSRVTTADEALKSVNSGDRLYLTGNASVPLQLLDALVRRAPELRDVEVSQVLTICPQDYVSPEMQ
GHVRVNTMFISPNVRQAVNEGRADFTPVLLSEFPLLFKNGHLPLDVALLNVSLPDENGFCSLGGEAGLTMTAAESARIVI
AQVNKKMPRTLGDTFFHVSRMTHIVEVDAPLTERHMAEEGDPEIVEQIAGHISSLIPDGATMQLGIGAIPDAVLKHLFSK
KDLGIHSELISDGVIDLVEAGVVNCSRKTLHPGKIVCGFLLGTKRLYDWAHNNPMIELRRTEYVNDPFVVAQNDRMVSVN
AAIEVDFTGQICADSIGPRMYSAVGGQMDFVYGASRSKGGVAVITMPSTSTLRDGSVVSKITPLLKHGAGVVTSRNHVRY
LVTEYGAADLYAKSVRQRTQALIGVAHPMFREELTEKAKELRYI

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=473, Percent_Identity=23.0443974630021, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17538151, Length=433, Percent_Identity=43.64896073903, Blast_Score=348, Evalue=3e-96,
Organism=Caenorhabditis elegans, GI32563853, Length=428, Percent_Identity=41.3551401869159, Blast_Score=337, Evalue=6e-93,
Organism=Saccharomyces cerevisiae, GI6319456, Length=393, Percent_Identity=23.6641221374046, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358615, Length=428, Percent_Identity=45.0934579439252, Blast_Score=366, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48775; Mature: 48643

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIWKEIKNWREIYNSRVTTADEALKSVNSGDRLYLTGNASVPLQLLDALVRRAPELR
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCC
DVEVSQVLTICPQDYVSPEMQGHVRVNTMFISPNVRQAVNEGRADFTPVLLSEFPLLFKN
CCCHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCHHHHHCCCCEEEC
GHLPLDVALLNVSLPDENGFCSLGGEAGLTMTAAESARIVIAQVNKKMPRTLGDTFFHVS
CCCCEEEEEEEEECCCCCCCEECCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHH
RMTHIVEVDAPLTERHMAEEGDPEIVEQIAGHISSLIPDGATMQLGIGAIPDAVLKHLFS
HHHEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHC
KKDLGIHSELISDGVIDLVEAGVVNCSRKTLHPGKIVCGFLLGTKRLYDWAHNNPMIELR
CCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
RTEYVNDPFVVAQNDRMVSVNAAIEVDFTGQICADSIGPRMYSAVGGQMDFVYGASRSKG
CCCCCCCCEEEECCCEEEEEEEEEEEECCCHHHHHHCCHHHHHHHCCCEEEEEECCCCCC
GVAVITMPSTSTLRDGSVVSKITPLLKHGAGVVTSRNHVRYLVTEYGAADLYAKSVRQRT
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHH
QALIGVAHPMFREELTEKAKELRYI
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AATIWKEIKNWREIYNSRVTTADEALKSVNSGDRLYLTGNASVPLQLLDALVRRAPELR
CHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCC
DVEVSQVLTICPQDYVSPEMQGHVRVNTMFISPNVRQAVNEGRADFTPVLLSEFPLLFKN
CCCHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCHHHHHHCCCCCCCHHHHHCCCCEEEC
GHLPLDVALLNVSLPDENGFCSLGGEAGLTMTAAESARIVIAQVNKKMPRTLGDTFFHVS
CCCCEEEEEEEEECCCCCCCEECCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHH
RMTHIVEVDAPLTERHMAEEGDPEIVEQIAGHISSLIPDGATMQLGIGAIPDAVLKHLFS
HHHEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHC
KKDLGIHSELISDGVIDLVEAGVVNCSRKTLHPGKIVCGFLLGTKRLYDWAHNNPMIELR
CCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEE
RTEYVNDPFVVAQNDRMVSVNAAIEVDFTGQICADSIGPRMYSAVGGQMDFVYGASRSKG
CCCCCCCCEEEECCCEEEEEEEEEEEECCCHHHHHHCCHHHHHHHCCCEEEEEECCCCCC
GVAVITMPSTSTLRDGSVVSKITPLLKHGAGVVTSRNHVRYLVTEYGAADLYAKSVRQRT
CEEEEEECCCCCCCCCHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCHHHHHHHHHHHH
QALIGVAHPMFREELTEKAKELRYI
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]