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The map label for this gene is moaC-1 [H]

Identifier: 197117736

GI number: 197117736

Start: 1554628

End: 1555104

Strand: Reverse

Name: moaC-1 [H]

Synonym: Gbem_1348

Alternate gene names: 197117736

Gene position: 1555104-1554628 (Counterclockwise)

Preceding gene: 197117737

Following gene: 308535231

Centisome position: 33.7

GC content: 66.46

Gene sequence:

>477_bases
ATGTTCAACCACTTCGACGAGCAGGGACAGGCCATCATGGTCGACGTGAGCGGCAAAACCTGCACGCTCAGGACCGCGAC
CGCACAGGCCCGGGTGCTGCTGAAACCGGCAACCCTGGCCGCCATCCTGGAAGGCTCGGTCGCCAAGGGGGACGTTTTGG
GCGTCGCCCGCCTGGCCGGCATCGCCGCGGCCAAGAAGACCCCCGACCTGATCCCCCTCTCCCACCCGCTGGCGATCCAC
CACGCCGCCATAGAGTTCCGGCACGACCCGGCCACAGGCGAGTTGAGGATAGAGGCGACGGTTCGGGCCTTCGAGCGGAC
CGGCGTCGAGATGGAGGCGATGACAGCCGCCTCGGTCGCGGCGCTCACCGTGTACGACATGTGCAAGGGGAGCGACAAGT
CGATAGCGATAGCGGAAGTGGTGCTGATGTTCAAGGAAGGGGGCAAGAGCGGGACCTACCGTCGCGGCGAGTCGTAG

Upstream 100 bases:

>100_bases
CCTTCGTCCCGGCAGGAAGCGAGGTCGATCTGGTCCTCTTGAGGGACGTGGAGCTGGTGCCGGAAACCACCTCGTAGCCG
CAGGCGAAACAGGAGAAACC

Downstream 100 bases:

>100_bases
AGCCGGGGGAATCCATTCTCTTTTTGCTATATACCTTTTCCTGAATATGAGTTATAGTGCTCGCATCTCAGGAGGTGAAC
CCGAACATGAACGAACTATT

Product: pyranopterin monophosphate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MFNHFDEQGQAIMVDVSGKTCTLRTATAQARVLLKPATLAAILEGSVAKGDVLGVARLAGIAAAKKTPDLIPLSHPLAIH
HAAIEFRHDPATGELRIEATVRAFERTGVEMEAMTAASVAALTVYDMCKGSDKSIAIAEVVLMFKEGGKSGTYRRGES

Sequences:

>Translated_158_residues
MFNHFDEQGQAIMVDVSGKTCTLRTATAQARVLLKPATLAAILEGSVAKGDVLGVARLAGIAAAKKTPDLIPLSHPLAIH
HAAIEFRHDPATGELRIEATVRAFERTGVEMEAMTAASVAALTVYDMCKGSDKSIAIAEVVLMFKEGGKSGTYRRGES
>Mature_158_residues
MFNHFDEQGQAIMVDVSGKTCTLRTATAQARVLLKPATLAAILEGSVAKGDVLGVARLAGIAAAKKTPDLIPLSHPLAIH
HAAIEFRHDPATGELRIEATVRAFERTGVEMEAMTAASVAALTVYDMCKGSDKSIAIAEVVLMFKEGGKSGTYRRGES

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=153, Percent_Identity=50.3267973856209, Blast_Score=148, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32566331, Length=153, Percent_Identity=41.8300653594771, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28574490, Length=153, Percent_Identity=47.7124183006536, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=47.887323943662, Blast_Score=118, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16708; Mature: 16708

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNHFDEQGQAIMVDVSGKTCTLRTATAQARVLLKPATLAAILEGSVAKGDVLGVARLAG
CCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECHHHHHHHHCCCCCCCCHHHHHHHHH
IAAAKKTPDLIPLSHPLAIHHAAIEFRHDPATGELRIEATVRAFERTGVEMEAMTAASVA
HHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEHEEEHHHHCCCEEEHHHHHHHH
ALTVYDMCKGSDKSIAIAEVVLMFKEGGKSGTYRRGES
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFNHFDEQGQAIMVDVSGKTCTLRTATAQARVLLKPATLAAILEGSVAKGDVLGVARLAG
CCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECHHHHHHHHCCCCCCCCHHHHHHHHH
IAAAKKTPDLIPLSHPLAIHHAAIEFRHDPATGELRIEATVRAFERTGVEMEAMTAASVA
HHHCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEEEEHEEEHHHHCCCEEEHHHHHHHH
ALTVYDMCKGSDKSIAIAEVVLMFKEGGKSGTYRRGES
HHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA