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The map label for this gene is arsR [C]

Identifier: 197117733

GI number: 197117733

Start: 1550501

End: 1551418

Strand: Direct

Name: arsR [C]

Synonym: Gbem_1345

Alternate gene names: 197117733

Gene position: 1550501-1551418 (Clockwise)

Preceding gene: 197117732

Following gene: 197117734

Centisome position: 33.6

GC content: 64.38

Gene sequence:

>918_bases
ATGATCGATTTACTAAAAGCTCTGGCTGATCCTTGCCGCCTCCGTCTGGTGGGGGCGCTTCTGCGCGCCGAACTCACGGT
GCAGGAGCTGACCCAGATCCTCGGCATGGGGCAGTCGCGCATCTCGCGGCACCTGAAGATCCTCACCGAGGCGGGGGTCC
TGTCGGTCAAGCGCCAGGGAACCTGGAGCTACTACCGGGCGGGAGAGGGAAACGCCTTTTTCTGCGCCATCCGTCCCCAG
TTCGAGCTGGAGTTGGAGCGGCTTCCTGAGCGAAACGACGATCTCGCGGCGGTGGCGCTGGCCCTGGAGGCAAGGCGCAG
GCGCAGCCTTGAGTTTTTCGACCAGCACGCGGCGCAGTGGGATGTCCTGTCGCGCACGCTGCTGCCGGTTCCGCCCTACC
TCGACCGTCTGCTGGGCCGGATTCCTGCCGTGGAAACCGTGCTTGAGATCGGCGTCGGCACCGGCGCGCTCTTGCCCGAA
TTATGCTTGCATGCAGCAAAGGTTATCGGCGTGGATCATTCGCCGGCCATGCTCGAAGAGGCGCGCCAGCGCATCACCAG
CGGCGGAAACCAGGGAGCCGAGCTGCGGCTGGGCGAGATGACGCATCTCCCCATAGCCGACGGCGGGGCGGGGTGTGTCA
TAGCAAACATGGTGCTGCACCATGCCGCCGATCCTATGACAGTACTGGGTGAGATTCAGCGGGTGCTCCAGCCCGGCGGG
GCGCTGGTCATGGCTGACCTGGCACGCCATGAGCGGGAATGGGCTCGCGAGCAGTTGGCGGATCAGTGGCTGGGTTTCGA
GGAAGAAGAACTGAAGGGTTGGATCGCCGCAGCCGGTTTCGGCGCGGTAGAGATAGAGCGGATAGCCGCCGGGGCCGGGC
AAGAACCCGTCCTGCTGGTAAAGGCGGTAAAGGAATAA

Upstream 100 bases:

>100_bases
AAAATTGGAGCTAAATAATTCATCTTTGCGCTTGATGCCGGTCCTTGCATATGCTATATCAAGAAAACTTGATTTAATAG
AACCGTCAGGGTTGATGGAC

Downstream 100 bases:

>100_bases
AAGGGGACAGGCTACTTTTTCAAACGAAAAAGTAGCCTGTCCCCCTTAAATGACGAATTGTTGCAGATAACCCACCAAAA
GGAGAAGCATCGATGAAAGA

Product: bifunctional helix-turn-helix metal-dependent transcriptional regulator/SAM-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MIDLLKALADPCRLRLVGALLRAELTVQELTQILGMGQSRISRHLKILTEAGVLSVKRQGTWSYYRAGEGNAFFCAIRPQ
FELELERLPERNDDLAAVALALEARRRRSLEFFDQHAAQWDVLSRTLLPVPPYLDRLLGRIPAVETVLEIGVGTGALLPE
LCLHAAKVIGVDHSPAMLEEARQRITSGGNQGAELRLGEMTHLPIADGGAGCVIANMVLHHAADPMTVLGEIQRVLQPGG
ALVMADLARHEREWAREQLADQWLGFEEEELKGWIAAAGFGAVEIERIAAGAGQEPVLLVKAVKE

Sequences:

>Translated_305_residues
MIDLLKALADPCRLRLVGALLRAELTVQELTQILGMGQSRISRHLKILTEAGVLSVKRQGTWSYYRAGEGNAFFCAIRPQ
FELELERLPERNDDLAAVALALEARRRRSLEFFDQHAAQWDVLSRTLLPVPPYLDRLLGRIPAVETVLEIGVGTGALLPE
LCLHAAKVIGVDHSPAMLEEARQRITSGGNQGAELRLGEMTHLPIADGGAGCVIANMVLHHAADPMTVLGEIQRVLQPGG
ALVMADLARHEREWAREQLADQWLGFEEEELKGWIAAAGFGAVEIERIAAGAGQEPVLLVKAVKE
>Mature_305_residues
MIDLLKALADPCRLRLVGALLRAELTVQELTQILGMGQSRISRHLKILTEAGVLSVKRQGTWSYYRAGEGNAFFCAIRPQ
FELELERLPERNDDLAAVALALEARRRRSLEFFDQHAAQWDVLSRTLLPVPPYLDRLLGRIPAVETVLEIGVGTGALLPE
LCLHAAKVIGVDHSPAMLEEARQRITSGGNQGAELRLGEMTHLPIADGGAGCVIANMVLHHAADPMTVLGEIQRVLQPGG
ALVMADLARHEREWAREQLADQWLGFEEEELKGWIAAAGFGAVEIERIAAGAGQEPVLLVKAVKE

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: NA

Molecular weight: Translated: 33357; Mature: 33357

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLLKALADPCRLRLVGALLRAELTVQELTQILGMGQSRISRHLKILTEAGVLSVKRQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHEEECCC
TWSYYRAGEGNAFFCAIRPQFELELERLPERNDDLAAVALALEARRRRSLEFFDQHAAQW
CCCEEECCCCCEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLSRTLLPVPPYLDRLLGRIPAVETVLEIGVGTGALLPELCLHAAKVIGVDHSPAMLEE
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
ARQRITSGGNQGAELRLGEMTHLPIADGGAGCVIANMVLHHAADPMTVLGEIQRVLQPGG
HHHHHHCCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ALVMADLARHEREWAREQLADQWLGFEEEELKGWIAAAGFGAVEIERIAAGAGQEPVLLV
CEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEE
KAVKE
EECCC
>Mature Secondary Structure
MIDLLKALADPCRLRLVGALLRAELTVQELTQILGMGQSRISRHLKILTEAGVLSVKRQG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHEEECCC
TWSYYRAGEGNAFFCAIRPQFELELERLPERNDDLAAVALALEARRRRSLEFFDQHAAQW
CCCEEECCCCCEEEEEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
DVLSRTLLPVPPYLDRLLGRIPAVETVLEIGVGTGALLPELCLHAAKVIGVDHSPAMLEE
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHH
ARQRITSGGNQGAELRLGEMTHLPIADGGAGCVIANMVLHHAADPMTVLGEIQRVLQPGG
HHHHHHCCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ALVMADLARHEREWAREQLADQWLGFEEEELKGWIAAAGFGAVEIERIAAGAGQEPVLLV
CEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEE
KAVKE
EECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]