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The map label for this gene is phoP [H]

Identifier: 197117730

GI number: 197117730

Start: 1547397

End: 1548101

Strand: Reverse

Name: phoP [H]

Synonym: Gbem_1342

Alternate gene names: 197117730

Gene position: 1548101-1547397 (Counterclockwise)

Preceding gene: 308535231

Following gene: 197117728

Centisome position: 33.54

GC content: 62.41

Gene sequence:

>705_bases
ATGGCGGGAGAAAAGCCACAGATACTCCTGGTCGAGGACGAGATGCACCTGGCGCGGGGCATCACCTTCAACCTGGAGCA
GGAAGGTTACTTGGTAAGCCACGTAGAAAGCGGCGAGGAGGCGCTGGAGAAGGTGAAGGTCGAGAAATTCGATCTCATCA
TCCTTGACGTCATGCTCCCCGGAATCGGCGGGTTCGAGGTATGCGAGAGGATACGGACGCTGGACTCCAGGGTGCCGGTG
CTGATGCTGACGGCGCGCTCCGCCGAGAGCGACCGCATCCATGGCCTGGCCGCCGGCGCCGACGACTACCTGATCAAGCC
CTTCAACCTGAAGGAGTTCCTGCTGAGGGTGTCGGGGATGTTGAGGCGTTCTGCCTGGTACCGTCCGGAGCCGGTCGAGG
AAGGATATCGTTTCGGCGACAACGAGGTGTTCCTCCTCTCTTACCGGGCGCGGACCCGGCAAGGGGAGATCGACCTGACC
GACCTGGAAGTGCGCATGCTCTCCCTGTTCTTTCACCGGGAGGGGGAGGCGATCCCGCGCGGGGTGATCCTGGAGAGCGT
CTGGGGGTACTCGACAGACGCCGAGACGAGGACCCTCGACAACTTCATCGTGCGGCTGCGGAAGTACTTCGAGCCGGAGC
CCTCCCGCCCCATCTTCTTCCAGACCGTGCGCGGGGTAGGCTACAGGTTCAGCAGGAATCCATAA

Upstream 100 bases:

>100_bases
GGCGGCAGGATCACCGTCAGCAGCGAGGGGCTCGGCAAGGGGTGCACCTTCCACATCGCGCTGCCGCTACCCGGCGGCCA
GCAGCAACGAGGTTAGCGGC

Downstream 100 bases:

>100_bases
CGGCCGTTCAATGTTCAATGTTCAACGTTCGCTGCCCCCACCGCGGAGTCGGCAACGTCCTCCACACATCCAACAGATTG
ATTCACAAGAAAAGGCCCCC

Product: winged-helix transcriptional response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAGEKPQILLVEDEMHLARGITFNLEQEGYLVSHVESGEEALEKVKVEKFDLIILDVMLPGIGGFEVCERIRTLDSRVPV
LMLTARSAESDRIHGLAAGADDYLIKPFNLKEFLLRVSGMLRRSAWYRPEPVEEGYRFGDNEVFLLSYRARTRQGEIDLT
DLEVRMLSLFFHREGEAIPRGVILESVWGYSTDAETRTLDNFIVRLRKYFEPEPSRPIFFQTVRGVGYRFSRNP

Sequences:

>Translated_234_residues
MAGEKPQILLVEDEMHLARGITFNLEQEGYLVSHVESGEEALEKVKVEKFDLIILDVMLPGIGGFEVCERIRTLDSRVPV
LMLTARSAESDRIHGLAAGADDYLIKPFNLKEFLLRVSGMLRRSAWYRPEPVEEGYRFGDNEVFLLSYRARTRQGEIDLT
DLEVRMLSLFFHREGEAIPRGVILESVWGYSTDAETRTLDNFIVRLRKYFEPEPSRPIFFQTVRGVGYRFSRNP
>Mature_233_residues
AGEKPQILLVEDEMHLARGITFNLEQEGYLVSHVESGEEALEKVKVEKFDLIILDVMLPGIGGFEVCERIRTLDSRVPVL
MLTARSAESDRIHGLAAGADDYLIKPFNLKEFLLRVSGMLRRSAWYRPEPVEEGYRFGDNEVFLLSYRARTRQGEIDLTD
LEVRMLSLFFHREGEAIPRGVILESVWGYSTDAETRTLDNFIVRLRKYFEPEPSRPIFFQTVRGVGYRFSRNP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=37.7777777777778, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=37.219730941704, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=36.5638766519824, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=37.7777777777778, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=36.0869565217391, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=37.5545851528384, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=34.8017621145374, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=33.0472103004292, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=31.390134529148, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=31.6239316239316, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=33.1896551724138, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=28.4444444444444, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=33.920704845815, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=140, Percent_Identity=30.7142857142857, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=107, Percent_Identity=34.5794392523364, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=29.3103448275862, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=94, Percent_Identity=38.2978723404255, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26963; Mature: 26832

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGEKPQILLVEDEMHLARGITFNLEQEGYLVSHVESGEEALEKVKVEKFDLIILDVMLP
CCCCCCCEEEEECCHHHHCCCEEEECCCCEEEEEHHCHHHHHHHHHHHHHHEEEEEECCC
GIGGFEVCERIRTLDSRVPVLMLTARSAESDRIHGLAAGADDYLIKPFNLKEFLLRVSGM
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHH
LRRSAWYRPEPVEEGYRFGDNEVFLLSYRARTRQGEIDLTDLEVRMLSLFFHREGEAIPR
HHHHCCCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GVILESVWGYSTDAETRTLDNFIVRLRKYFEPEPSRPIFFQTVRGVGYRFSRNP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHCCCEEECCCC
>Mature Secondary Structure 
AGEKPQILLVEDEMHLARGITFNLEQEGYLVSHVESGEEALEKVKVEKFDLIILDVMLP
CCCCCCEEEEECCHHHHCCCEEEECCCCEEEEEHHCHHHHHHHHHHHHHHEEEEEECCC
GIGGFEVCERIRTLDSRVPVLMLTARSAESDRIHGLAAGADDYLIKPFNLKEFLLRVSGM
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHHH
LRRSAWYRPEPVEEGYRFGDNEVFLLSYRARTRQGEIDLTDLEVRMLSLFFHREGEAIPR
HHHHCCCCCCCHHHCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GVILESVWGYSTDAETRTLDNFIVRLRKYFEPEPSRPIFFQTVRGVGYRFSRNP
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]