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The map label for this gene is iscR [H]

Identifier: 197117656

GI number: 197117656

Start: 1464794

End: 1465207

Strand: Direct

Name: iscR [H]

Synonym: Gbem_1268

Alternate gene names: 197117656

Gene position: 1464794-1465207 (Clockwise)

Preceding gene: 197117655

Following gene: 197117657

Centisome position: 31.74

GC content: 64.98

Gene sequence:

>414_bases
ATGATGGAACTGACCCGAAAGGGTGAATACGCCATACGTGGCATCATCTACCTGGCACAGCAGCCGCCTGGCCGTGTTTC
GCTGATCAGCGAGATCGCCGCAGCGGCCGAGGTCCCGCAGACCTTCCTGGCCAAGATCTTCCAGAGCTTTGCGAAGCTGG
GGCTGGTTACTTCCTCTCGCGGCACCGGCGGTGGCTTCGTTCTCGCCCGCCCCGCCTCGCAGATCACGCTGCGGGAAGTG
GTAGAGGCGGTGGAGGGACCGATCCTTCCCAACCGTTGCCTTCTGGGAAGCGCCTGTGACAGGGGTGGCCCCTGCCGCGT
TCACGGGGTCTGGAAGCAGGTGCAGACCGAGGTGGTGCGCATCCTGGACGGGGTGACCATCGACTCTCTGGCGCGCAGCC
CGGAGCAGCAGTAG

Upstream 100 bases:

>100_bases
GCTCCCCCGATAGCCGCCGAGAATTTTCCTGGAGTTTCCGCTTGACAGGTTCCGGATGCTCCGCTATAAAAGGGATAAAT
TTGGTCCTAAAGGTGTTCTT

Downstream 100 bases:

>100_bases
GCGCGCGGCCTGAAAAAAATTTGCCGACAAATGAGATAAAGAAGGTCCTGTTTATCCCGTATACACTATTGGCTTGAACC
GGTTTTAATGATAGAAGTAC

Product: Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MMELTRKGEYAIRGIIYLAQQPPGRVSLISEIAAAAEVPQTFLAKIFQSFAKLGLVTSSRGTGGGFVLARPASQITLREV
VEAVEGPILPNRCLLGSACDRGGPCRVHGVWKQVQTEVVRILDGVTIDSLARSPEQQ

Sequences:

>Translated_137_residues
MMELTRKGEYAIRGIIYLAQQPPGRVSLISEIAAAAEVPQTFLAKIFQSFAKLGLVTSSRGTGGGFVLARPASQITLREV
VEAVEGPILPNRCLLGSACDRGGPCRVHGVWKQVQTEVVRILDGVTIDSLARSPEQQ
>Mature_137_residues
MMELTRKGEYAIRGIIYLAQQPPGRVSLISEIAAAAEVPQTFLAKIFQSFAKLGLVTSSRGTGGGFVLARPASQITLREV
VEAVEGPILPNRCLLGSACDRGGPCRVHGVWKQVQTEVVRILDGVTIDSLARSPEQQ

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=29.8507462686567, Blast_Score=70, Evalue=4e-14,
Organism=Escherichia coli, GI1790621, Length=129, Percent_Identity=32.5581395348837, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 14716; Mature: 14716

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMELTRKGEYAIRGIIYLAQQPPGRVSLISEIAAAAEVPQTFLAKIFQSFAKLGLVTSSR
CCCCCCCCCHHHHHEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
GTGGGFVLARPASQITLREVVEAVEGPILPNRCLLGSACDRGGPCRVHGVWKQVQTEVVR
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHH
ILDGVTIDSLARSPEQQ
HHCCCCHHHHHCCCCCC
>Mature Secondary Structure
MMELTRKGEYAIRGIIYLAQQPPGRVSLISEIAAAAEVPQTFLAKIFQSFAKLGLVTSSR
CCCCCCCCCHHHHHEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
GTGGGFVLARPASQITLREVVEAVEGPILPNRCLLGSACDRGGPCRVHGVWKQVQTEVVR
CCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHH
ILDGVTIDSLARSPEQQ
HHCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA