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The map label for this gene is acpS-1

Identifier: 197117648

GI number: 197117648

Start: 1457578

End: 1457955

Strand: Direct

Name: acpS-1

Synonym: Gbem_1260

Alternate gene names: 197117648

Gene position: 1457578-1457955 (Clockwise)

Preceding gene: 197117647

Following gene: 197117649

Centisome position: 31.58

GC content: 62.43

Gene sequence:

>378_bases
GTGATTTACGGCACGGGCGTTGACATAGTTGAGATCGCGAGGTTCGAGAAGTTCCTGCAGCAGGGGAACGATGCCCTCTT
CGACAGGATCTTCACACCCTCCGAGATAGAGTACTGCTCCGCTAAGAAACATAGCGCGCAGCACTACGCGCTCCGCTTCG
CGGCCAAGGAGTCCTTCCTGAAGGCGCTGGGGACCGGCCTGCGCGACGGCATCTCCTGGAAGGACATGGAAGTGGTCAAC
GACCAGCTGGGCAAGCCGGAGCTCAGGCTTTACCGGCGCGCCGAGGAGCTGTTCCGGCAGGCGGGGCTTTGCTCCTGTTT
CCTGTCGCTGTCGCACGACGCGGGATGCGCCGTCGCCATGGTGGTACTGGAGCGCTAG

Upstream 100 bases:

>100_bases
AGTGAGCCGTTGTTGTGAGTATCAGCGTGAACGGTTATAGTGTTAGCAGGACCGCGAGATCGATTCGATCTGACAGATCT
CCCGGAAGACAGGAGCTTTT

Downstream 100 bases:

>100_bases
ATGAAGGTGGTCACGGGACAGGTGATGCAGTCGATCGACAAAAGGGCCATCGGGGAGTTCGGGATCCCGGGGCTTGCGCT
CATGGAGCGCGCCGGCACCG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 125; Mature: 125

Protein sequence:

>125_residues
MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSAKKHSAQHYALRFAAKESFLKALGTGLRDGISWKDMEVVN
DQLGKPELRLYRRAEELFRQAGLCSCFLSLSHDAGCAVAMVVLER

Sequences:

>Translated_125_residues
MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSAKKHSAQHYALRFAAKESFLKALGTGLRDGISWKDMEVVN
DQLGKPELRLYRRAEELFRQAGLCSCFLSLSHDAGCAVAMVVLER
>Mature_125_residues
MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSAKKHSAQHYALRFAAKESFLKALGTGLRDGISWKDMEVVN
DQLGKPELRLYRRAEELFRQAGLCSCFLSLSHDAGCAVAMVVLER

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=38.2113821138211, Blast_Score=90, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325025, Length=120, Percent_Identity=36.6666666666667, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_GEOBB (B5EI15)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002138075.1
- ProteinModelPortal:   B5EI15
- SMR:   B5EI15
- GeneID:   6781244
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_1260
- HOGENOM:   HBG734479
- OMA:   NSSAIAY
- ProtClustDB:   PRK14656
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14109; Mature: 14109

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSAKKHSAQHYALRFAAKESFL
CEECCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHH
KALGTGLRDGISWKDMEVVNDQLGKPELRLYRRAEELFRQAGLCSCFLSLSHDAGCAVAM
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VVLER
HHHCC
>Mature Secondary Structure
MIYGTGVDIVEIARFEKFLQQGNDALFDRIFTPSEIEYCSAKKHSAQHYALRFAAKESFL
CEECCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHH
KALGTGLRDGISWKDMEVVNDQLGKPELRLYRRAEELFRQAGLCSCFLSLSHDAGCAVAM
HHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VVLER
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA