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The map label for this gene is rpfG [H]

Identifier: 197117600

GI number: 197117600

Start: 1404516

End: 1405772

Strand: Direct

Name: rpfG [H]

Synonym: Gbem_1212

Alternate gene names: 197117600

Gene position: 1404516-1405772 (Clockwise)

Preceding gene: 197117599

Following gene: 197117601

Centisome position: 30.43

GC content: 60.38

Gene sequence:

>1257_bases
ATGAATGGACCAGACAGCAAGCTGATCAAGGCACTGCATCTCGGTCTGGAGATATCGCAGATCAAAGATATCGACCTGCT
TCTGGAGAAGATACTGACAGAGGCGCGCCGCTTCACCAATTGCGACGCAGGTTCCATCTATGTGAAGGAAGGTGACCTGC
TCAAGTTCAGTTACGCCCAGAACGACACCATGCAGCGCCGGTTGCCGGTGGGGCGCAAACTCCCCTATGCGACCTTCACC
GTTCCCATCAGCAGCAGTTCGATAGCCGGCTATGTCTCCCTGAACGGCTCCATCCTCAATATCCCGGACGTCTCCTGCAT
CGATCCGGTCTACCCCTTTTCTTTCAACAGCCGCTACGACGAGATCGGCTACCGTACCCGCTCCATGCTCACCGTCCCTC
TCAAGAACCACCGGGGCGATGTGATAGGCGTGCTGCAGCTGATCAACGCCATGGACGCCTGCGGGAGCGTAGTTCCTTTC
ACCGACAATAACGACGATATCATCACCTACTTCTCCAATGCCGCGGCCAATGCGGTGGAGCGCGCCAAGATGACCCGGGA
GATCATCCTGAGGATGAACCGGATGGCCGAGATGCGCGACCCGAAGGAGACCGGCCCGCACGTGAACCGGGTGGCCTCCT
ACGCCGTTGCGCTCTATGAGGCGTGGGCTGCGAGAAACGGGCTGTCGCAGCAGGAGATCGACAAGAACCGCGACGTGCTG
CGCATGGCGGCCATGCTGCACGACGTGGGGAAGGTCGCCATCTCGGACACCATCCTGAAGAAACCCGGACGCTTCAAGCC
GGAAGAGTTCGCCATCATGAAGCAGCACACCGTCTACGGCGCCGATCTTTTCAGCGACATCTATTCCGACTTCGACGAGT
CGGCGGCGGTGGTGATCATAAACCACCATGAGAGATGGGACGGCAAGGGGTACCCCGGGCACATCGATCCGCGCACCCGC
CAACCCTTGCCCGGGTTCGAGACGGAACAGGGGGGAGCGCGCGGCAAGCGGGGGGAGGAGATCCCGCTCTTCGGCAGGAT
CGTCGCCATAGCCGACGTCTTCGACGCGCTCACCAGCAGCAGGTGCTACAAGGACGCCTGGGACTGCGACAAGGTCCTCG
ACACCATAAAGGAAGAGGCGGGCAAGCAGTTTGACCCGGAACTGGTCGAGGTGCTGTTGGAATGCTGCCTGGATTCCTTC
CTCCAGATCGCCAAGCTTTACCCGGACCAGCACGCATCTCCCTTGGCGGCGCCCTGA

Upstream 100 bases:

>100_bases
ACGCTGCATTTACTGCCTTAGATGTTGCAAAAACCCCTCTTTAGTGGAACAATACCGCGAGCTTTAAGCCGGTTTTACTC
TTTGAAGAGGGGCTGAGACT

Downstream 100 bases:

>100_bases
TCGCTCCCGGGTACGGGTGAGCCGACGCAGTTTCCGAGGGGGAGGAAGGGTAGGTTAGGAGGTTCCGTGAAGAGACTCTT
ATTGCTGGCGTTGCTGGTTC

Product: sensor cyclic diguanylate phosphodiesterase, GAF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNGPDSKLIKALHLGLEISQIKDIDLLLEKILTEARRFTNCDAGSIYVKEGDLLKFSYAQNDTMQRRLPVGRKLPYATFT
VPISSSSIAGYVSLNGSILNIPDVSCIDPVYPFSFNSRYDEIGYRTRSMLTVPLKNHRGDVIGVLQLINAMDACGSVVPF
TDNNDDIITYFSNAAANAVERAKMTREIILRMNRMAEMRDPKETGPHVNRVASYAVALYEAWAARNGLSQQEIDKNRDVL
RMAAMLHDVGKVAISDTILKKPGRFKPEEFAIMKQHTVYGADLFSDIYSDFDESAAVVIINHHERWDGKGYPGHIDPRTR
QPLPGFETEQGGARGKRGEEIPLFGRIVAIADVFDALTSSRCYKDAWDCDKVLDTIKEEAGKQFDPELVEVLLECCLDSF
LQIAKLYPDQHASPLAAP

Sequences:

>Translated_418_residues
MNGPDSKLIKALHLGLEISQIKDIDLLLEKILTEARRFTNCDAGSIYVKEGDLLKFSYAQNDTMQRRLPVGRKLPYATFT
VPISSSSIAGYVSLNGSILNIPDVSCIDPVYPFSFNSRYDEIGYRTRSMLTVPLKNHRGDVIGVLQLINAMDACGSVVPF
TDNNDDIITYFSNAAANAVERAKMTREIILRMNRMAEMRDPKETGPHVNRVASYAVALYEAWAARNGLSQQEIDKNRDVL
RMAAMLHDVGKVAISDTILKKPGRFKPEEFAIMKQHTVYGADLFSDIYSDFDESAAVVIINHHERWDGKGYPGHIDPRTR
QPLPGFETEQGGARGKRGEEIPLFGRIVAIADVFDALTSSRCYKDAWDCDKVLDTIKEEAGKQFDPELVEVLLECCLDSF
LQIAKLYPDQHASPLAAP
>Mature_418_residues
MNGPDSKLIKALHLGLEISQIKDIDLLLEKILTEARRFTNCDAGSIYVKEGDLLKFSYAQNDTMQRRLPVGRKLPYATFT
VPISSSSIAGYVSLNGSILNIPDVSCIDPVYPFSFNSRYDEIGYRTRSMLTVPLKNHRGDVIGVLQLINAMDACGSVVPF
TDNNDDIITYFSNAAANAVERAKMTREIILRMNRMAEMRDPKETGPHVNRVASYAVALYEAWAARNGLSQQEIDKNRDVL
RMAAMLHDVGKVAISDTILKKPGRFKPEEFAIMKQHTVYGADLFSDIYSDFDESAAVVIINHHERWDGKGYPGHIDPRTR
QPLPGFETEQGGARGKRGEEIPLFGRIVAIADVFDALTSSRCYKDAWDCDKVLDTIKEEAGKQFDPELVEVLLECCLDSF
LQIAKLYPDQHASPLAAP

Specific function: Positively regulates the synthesis of extracellular enzymes and extracellular polysaccharides. The cell-cell signaling system encoded by rpf genes is required for full virulence and is implicated in regulation of the formation and dispersal of biofilms [H

COG id: COG3437

COG function: function code KT; Response regulator containing a CheY-like receiver domain and an HD-GYP domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI4505657, Length=173, Percent_Identity=27.1676300578035, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI219802706, Length=173, Percent_Identity=27.1676300578035, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI226246591, Length=173, Percent_Identity=27.1676300578035, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR003607
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 46669; Mature: 46669

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGPDSKLIKALHLGLEISQIKDIDLLLEKILTEARRFTNCDAGSIYVKEGDLLKFSYAQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCC
NDTMQRRLPVGRKLPYATFTVPISSSSIAGYVSLNGSILNIPDVSCIDPVYPFSFNSRYD
CCHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCCCHH
EIGYRTRSMLTVPLKNHRGDVIGVLQLINAMDACGSVVPFTDNNDDIITYFSNAAANAVE
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEECHHHHHHHH
RAKMTREIILRMNRMAEMRDPKETGPHVNRVASYAVALYEAWAARNGLSQQEIDKNRDVL
HHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHH
RMAAMLHDVGKVAISDTILKKPGRFKPEEFAIMKQHTVYGADLFSDIYSDFDESAAVVII
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
NHHERWDGKGYPGHIDPRTRQPLPGFETEQGGARGKRGEEIPLFGRIVAIADVFDALTSS
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
RCYKDAWDCDKVLDTIKEEAGKQFDPELVEVLLECCLDSFLQIAKLYPDQHASPLAAP
HHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNGPDSKLIKALHLGLEISQIKDIDLLLEKILTEARRFTNCDAGSIYVKEGDLLKFSYAQ
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCC
NDTMQRRLPVGRKLPYATFTVPISSSSIAGYVSLNGSILNIPDVSCIDPVYPFSFNSRYD
CCHHHHHCCCCCCCCCEEEEEEECCCCEEEEEEECCCEEECCCCCCCCCCCCCCCCCCHH
EIGYRTRSMLTVPLKNHRGDVIGVLQLINAMDACGSVVPFTDNNDDIITYFSNAAANAVE
HHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEECHHHHHHHH
RAKMTREIILRMNRMAEMRDPKETGPHVNRVASYAVALYEAWAARNGLSQQEIDKNRDVL
HHHHHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHH
RMAAMLHDVGKVAISDTILKKPGRFKPEEFAIMKQHTVYGADLFSDIYSDFDESAAVVII
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
NHHERWDGKGYPGHIDPRTRQPLPGFETEQGGARGKRGEEIPLFGRIVAIADVFDALTSS
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
RCYKDAWDCDKVLDTIKEEAGKQFDPELVEVLLECCLDSFLQIAKLYPDQHASPLAAP
HHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11123673 [H]