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The map label for this gene is fnr-2 [H]

Identifier: 197117452

GI number: 197117452

Start: 1235171

End: 1235887

Strand: Direct

Name: fnr-2 [H]

Synonym: Gbem_1063

Alternate gene names: 197117452

Gene position: 1235171-1235887 (Clockwise)

Preceding gene: 197117451

Following gene: 197117453

Centisome position: 26.76

GC content: 56.9

Gene sequence:

>717_bases
GTGCAAGCAGAGGGCGAAAAGGGCATAGAGGAATCCGGCCGAACAAGGCTTTTGCGGGCGATCCCGCTCTTTTCTTGCCT
GGACCCACTGGAGTTCTCGGAGGTCCAGCGCAGGATAATGGAGAAGCGCTTTCACAAGAACCAGGTTGTGCTTCTCGAGG
AGGACACTGCAAACTACATGTACATAGTTTATGGAGGCAAGGTCCGTGTAGTTCACCTGGGAAGCGAGGGGAGCGAGAGG
ATCCTTGCCGTCCATAAACGCGGGGACGTCTTTGGCGAGATGGCGCTGCTCGATGCCAAGACGGCCCCGGCAACGGTCAT
CGCCATGGAGGACGCCGAAATCGGGCTCCTTTCCAAGGAAACCTTCGATACCTTCTTCCTCGGCAATCATAGGGTGCTGT
TGCAACTGGTCGCGATCCTTTGCCGCAGGCTAAGAGAGGCCCAACTAGTGCTCAAAGCGATCACCCTACCCGATGCGGAA
CAAAGGCTGCGCTCGATTCTGAACCATTTGAGCCAGTTGCACGGGGTGCGTGATGCCCGAGGGATTGTGATCGCCTTGAG
GCTCACTCACAAGGAACTCGCGGGATACACCTCGGTTTCGCGGGAGACAGTGACCAGGCTGTTGCACCGGATGGTCCTGG
AAGGCGATCTGGAGATGCTGCAGAACCGAACCATTCTACTCAAACCGGGATTCAGGCAGAAAGCGCAGCTGCTTTAG

Upstream 100 bases:

>100_bases
GCTGTGCCTGGAAAAGATCGCCAACGGCATGACCGTGAGCATCGAGCAGTAAGCTGGCGAGGAAGCAAGGTGCGGCGAGG
CTGCACCGGCGGGGGGGCGT

Downstream 100 bases:

>100_bases
TTGGGCGGAATACTGCCAGTTCGGTGATTGAAGTCACAACTGCTGTGCCTTGACATGGCCAGGGGGGTAATTATACTTTC
GATTGTTAAAAAAAACTAAG

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MQAEGEKGIEESGRTRLLRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYMYIVYGGKVRVVHLGSEGSER
ILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKETFDTFFLGNHRVLLQLVAILCRRLREAQLVLKAITLPDAE
QRLRSILNHLSQLHGVRDARGIVIALRLTHKELAGYTSVSRETVTRLLHRMVLEGDLEMLQNRTILLKPGFRQKAQLL

Sequences:

>Translated_238_residues
MQAEGEKGIEESGRTRLLRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYMYIVYGGKVRVVHLGSEGSER
ILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKETFDTFFLGNHRVLLQLVAILCRRLREAQLVLKAITLPDAE
QRLRSILNHLSQLHGVRDARGIVIALRLTHKELAGYTSVSRETVTRLLHRMVLEGDLEMLQNRTILLKPGFRQKAQLL
>Mature_238_residues
MQAEGEKGIEESGRTRLLRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYMYIVYGGKVRVVHLGSEGSER
ILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKETFDTFFLGNHRVLLQLVAILCRRLREAQLVLKAITLPDAE
QRLRSILNHLSQLHGVRDARGIVIALRLTHKELAGYTSVSRETVTRLLHRMVLEGDLEMLQNRTILLKPGFRQKAQLL

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26989; Mature: 26989

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAEGEKGIEESGRTRLLRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYM
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEE
YIVYGGKVRVVHLGSEGSERILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKE
EEEECCEEEEEEECCCCCCEEEEEECCCCHHHHHHEEECCCCCEEEEEECCCCCCEECHH
TFDTFFLGNHRVLLQLVAILCRRLREAQLVLKAITLPDAEQRLRSILNHLSQLHGVRDAR
HHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
GIVIALRLTHKELAGYTSVSRETVTRLLHRMVLEGDLEMLQNRTILLKPGFRQKAQLL
CEEEEEEECHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCHHCCCC
>Mature Secondary Structure
MQAEGEKGIEESGRTRLLRAIPLFSCLDPLEFSEVQRRIMEKRFHKNQVVLLEEDTANYM
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCEE
YIVYGGKVRVVHLGSEGSERILAVHKRGDVFGEMALLDAKTAPATVIAMEDAEIGLLSKE
EEEECCEEEEEEECCCCCCEEEEEECCCCHHHHHHEEECCCCCEEEEEECCCCCCEECHH
TFDTFFLGNHRVLLQLVAILCRRLREAQLVLKAITLPDAEQRLRSILNHLSQLHGVRDAR
HHCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
GIVIALRLTHKELAGYTSVSRETVTRLLHRMVLEGDLEMLQNRTILLKPGFRQKAQLL
CEEEEEEECHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHCCEEEECCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8846791; 9384377 [H]