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The map label for this gene is bvgS [H]

Identifier: 197117430

GI number: 197117430

Start: 1211658

End: 1213430

Strand: Reverse

Name: bvgS [H]

Synonym: Gbem_1040

Alternate gene names: 197117430

Gene position: 1213430-1211658 (Counterclockwise)

Preceding gene: 197117431

Following gene: 197117429

Centisome position: 26.29

GC content: 63.4

Gene sequence:

>1773_bases
TTGAGGATACCAACAAGCAAAATACCGGTCGTCGTCCTTCTCAGCGCGGTGAGCATCGCGCTGGTGATGATGGCGTCAAG
CCACCTCATGCTCGGGCAGATCCGGGAGGAGGCCGTGCGCCAGGCCACCAGGCAGCAGGAAAGCAGCATGTCGGCCCTGT
GGGAGCAGATGGCGCGCCGCGGCAGGAACTTCCGCATCGAGGACGGCAAGCTCTACGTCGGGGACTACTACGTCCTGAAC
GACAACAACGAGATTCCGGACCGCATCTTCGCCATCACCGGGAGCAGGGCCACCATCTTCATGGGAGACATCCGGGTCGC
CACCAACATCATGCGGTCCGACGGCACCCGCGCGATAGGGACAAAGATGATCGGCCCCGCCTATCAGGCCATCTTCGGCG
AGGGAACCAGCTACCGCGGCGAGGCCGATATCCTCGGCATCCCCTACTTCACCGCCTACGACCCGGTGCGGGACATGCAC
GGCAAGACCATCGGCGCCCTCTTCGTGGGGGTGAAGCAGAGCGAGTACCTGGCCCGCTACGACAGCATCAACCTGAAAAT
CCGCGCCATCAGCGTGATGCTGGCAGCGATCTTCGTCCTTATGGCTGTGCTTTTGATCCAGGTCCGCAAGAAAAGCGAGA
TCGCGGCACAGCAGCAGCTCGCCTTCCAGCAGCTGCTTTTGGACACCATACCCAGCCCGATCTTTTCCAAGGACGCCCAA
GGGCGCTACAACCTCTGCAACAAGGCCTTCCAGGAGTACGTGGGGGTGCCGAGCGAGGAGCTTTTGGGGAAGACGGTTTT
TGACCTTTGGCCCAGGGAGCTGGCGGAGCAGTACCAGCGCATGGACCAGGTCATCATGGAAAGCTCCGGAACGCAGATCT
ACGAGTCGCAGGTCAAGTATGCGGACGGCACCCTGCACGACGTGCTCTTCCACAAGGCGGCTTTCCGGGACGAGAAGGGG
ACCCCCGCCGGGCTGGTCGGCGTCATCCTGGACATCACGGAGCGCAAGGAGGCCGAGATGGAGAACAGCAGACTCGCGGC
GCAGATGCACCAATCCCGGATGGTAGAGTCGCTGATGATCCAGCTGAACCACGACCTGAACACCCCGCTTACCCCCCTGT
TCGCCCTGCTCCCCATGATTGAGAAACAGGTGGACGACCCGGGGCTTAGGAGAATGCTGGAGATCTGCCAGCAGTGCGCA
AACCAGATCAAGGGGCTGGCCGAGAAGTCCCTGGACCTGGTCCGGATCTCGTCCGGCCGCCCGCAGCTGATCCCGGTCAG
GCTCGCCGGCACGGCGGAGTTCGCGTGCGGCGAAGTCGCGGACTCCCTGGCGCTGCGCGGCGTGACCTGCCACAACGACA
TCCCCGCCGACCTGTGGGTCTTGGGAAGCGCGGAACAGCTCTCACTGCTCTTCAGGAACCTGCTCACCAATGCCGCGCGC
TACGCCCGTGCCAACGGGCACATCGTGCTGGGGGCCGCGCCCATGGACGGCATGGTGCAGGTCTGCGTCCAGGACGACGG
CGAGGGGCTGGACCAGGAGCACTTGGCCCTGGTCTTCAACGAGTTCTTCAAGGCCGATCCGGCCCGCCAGGACGTGAACA
CGCAAGGGCTGGGGCTGGCCATCTGCAAGCGGATCATCGCCAACCACGACGGCAGGATCTGGGCCGAGAGCCCCGGCAAG
GGGCAAGGGACCACCATCTTCTTTACGCTTAACCCCGCCGGCGATGCGCCGGAGGAAGCCAAACCCGATCATCCGGAGAG
TTACGACATATGA

Upstream 100 bases:

>100_bases
AGAAAAAGGCGCCCTCACCCCGCCCCTCTCCCAGAGGGAGAGGGGGAATGGACAGAGGCATCGGTATGAAGCGGCATGGC
CGGTTGAGCTGAGGAAAGAC

Downstream 100 bases:

>100_bases
GCCGCCTTTCCATCGGACAACTCAAGGCGCGCATTGGCATCACCGTCGGGATCATCGTCGTCGCGGTATTGTGCATCTCC
GGCCTGGGGGACACCGCGAA

Product: PAS domain-containing sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MRIPTSKIPVVVLLSAVSIALVMMASSHLMLGQIREEAVRQATRQQESSMSALWEQMARRGRNFRIEDGKLYVGDYYVLN
DNNEIPDRIFAITGSRATIFMGDIRVATNIMRSDGTRAIGTKMIGPAYQAIFGEGTSYRGEADILGIPYFTAYDPVRDMH
GKTIGALFVGVKQSEYLARYDSINLKIRAISVMLAAIFVLMAVLLIQVRKKSEIAAQQQLAFQQLLLDTIPSPIFSKDAQ
GRYNLCNKAFQEYVGVPSEELLGKTVFDLWPRELAEQYQRMDQVIMESSGTQIYESQVKYADGTLHDVLFHKAAFRDEKG
TPAGLVGVILDITERKEAEMENSRLAAQMHQSRMVESLMIQLNHDLNTPLTPLFALLPMIEKQVDDPGLRRMLEICQQCA
NQIKGLAEKSLDLVRISSGRPQLIPVRLAGTAEFACGEVADSLALRGVTCHNDIPADLWVLGSAEQLSLLFRNLLTNAAR
YARANGHIVLGAAPMDGMVQVCVQDDGEGLDQEHLALVFNEFFKADPARQDVNTQGLGLAICKRIIANHDGRIWAESPGK
GQGTTIFFTLNPAGDAPEEAKPDHPESYDI

Sequences:

>Translated_590_residues
MRIPTSKIPVVVLLSAVSIALVMMASSHLMLGQIREEAVRQATRQQESSMSALWEQMARRGRNFRIEDGKLYVGDYYVLN
DNNEIPDRIFAITGSRATIFMGDIRVATNIMRSDGTRAIGTKMIGPAYQAIFGEGTSYRGEADILGIPYFTAYDPVRDMH
GKTIGALFVGVKQSEYLARYDSINLKIRAISVMLAAIFVLMAVLLIQVRKKSEIAAQQQLAFQQLLLDTIPSPIFSKDAQ
GRYNLCNKAFQEYVGVPSEELLGKTVFDLWPRELAEQYQRMDQVIMESSGTQIYESQVKYADGTLHDVLFHKAAFRDEKG
TPAGLVGVILDITERKEAEMENSRLAAQMHQSRMVESLMIQLNHDLNTPLTPLFALLPMIEKQVDDPGLRRMLEICQQCA
NQIKGLAEKSLDLVRISSGRPQLIPVRLAGTAEFACGEVADSLALRGVTCHNDIPADLWVLGSAEQLSLLFRNLLTNAAR
YARANGHIVLGAAPMDGMVQVCVQDDGEGLDQEHLALVFNEFFKADPARQDVNTQGLGLAICKRIIANHDGRIWAESPGK
GQGTTIFFTLNPAGDAPEEAKPDHPESYDI
>Mature_590_residues
MRIPTSKIPVVVLLSAVSIALVMMASSHLMLGQIREEAVRQATRQQESSMSALWEQMARRGRNFRIEDGKLYVGDYYVLN
DNNEIPDRIFAITGSRATIFMGDIRVATNIMRSDGTRAIGTKMIGPAYQAIFGEGTSYRGEADILGIPYFTAYDPVRDMH
GKTIGALFVGVKQSEYLARYDSINLKIRAISVMLAAIFVLMAVLLIQVRKKSEIAAQQQLAFQQLLLDTIPSPIFSKDAQ
GRYNLCNKAFQEYVGVPSEELLGKTVFDLWPRELAEQYQRMDQVIMESSGTQIYESQVKYADGTLHDVLFHKAAFRDEKG
TPAGLVGVILDITERKEAEMENSRLAAQMHQSRMVESLMIQLNHDLNTPLTPLFALLPMIEKQVDDPGLRRMLEICQQCA
NQIKGLAEKSLDLVRISSGRPQLIPVRLAGTAEFACGEVADSLALRGVTCHNDIPADLWVLGSAEQLSLLFRNLLTNAAR
YARANGHIVLGAAPMDGMVQVCVQDDGEGLDQEHLALVFNEFFKADPARQDVNTQGLGLAICKRIIANHDGRIWAESPGK
GQGTTIFFTLNPAGDAPEEAKPDHPESYDI

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=381, Percent_Identity=23.0971128608924, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=29.1845493562232, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788713, Length=429, Percent_Identity=23.3100233100233, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI145693157, Length=306, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788549, Length=372, Percent_Identity=21.7741935483871, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=31.496062992126, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=103, Percent_Identity=36.8932038834951, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789808, Length=223, Percent_Identity=26.457399103139, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=28.5087719298246, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 65336; Mature: 65336

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIPTSKIPVVVLLSAVSIALVMMASSHLMLGQIREEAVRQATRQQESSMSALWEQMARR
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRNFRIEDGKLYVGDYYVLNDNNEIPDRIFAITGSRATIFMGDIRVATNIMRSDGTRAIG
CCCEEEECCEEEEEEEEEECCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCHHHH
TKMIGPAYQAIFGEGTSYRGEADILGIPYFTAYDPVRDMHGKTIGALFVGVKQSEYLARY
HHHCCHHHHHHHCCCCCCCCCCCEEECCCHHCCCCHHHHCCCEEEHHEEECCHHHHHHHH
DSINLKIRAISVMLAAIFVLMAVLLIQVRKKSEIAAQQQLAFQQLLLDTIPSPIFSKDAQ
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
GRYNLCNKAFQEYVGVPSEELLGKTVFDLWPRELAEQYQRMDQVIMESSGTQIYESQVKY
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ADGTLHDVLFHKAAFRDEKGTPAGLVGVILDITERKEAEMENSRLAAQMHQSRMVESLMI
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNHDLNTPLTPLFALLPMIEKQVDDPGLRRMLEICQQCANQIKGLAEKSLDLVRISSGR
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
PQLIPVRLAGTAEFACGEVADSLALRGVTCHNDIPADLWVLGSAEQLSLLFRNLLTNAAR
CCEEEEEECCCCHHHHHHHHHHHHHCCEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHH
YARANGHIVLGAAPMDGMVQVCVQDDGEGLDQEHLALVFNEFFKADPARQDVNTQGLGLA
HHCCCCCEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
ICKRIIANHDGRIWAESPGKGQGTTIFFTLNPAGDAPEEAKPDHPESYDI
HHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIPTSKIPVVVLLSAVSIALVMMASSHLMLGQIREEAVRQATRQQESSMSALWEQMARR
CCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRNFRIEDGKLYVGDYYVLNDNNEIPDRIFAITGSRATIFMGDIRVATNIMRSDGTRAIG
CCCEEEECCEEEEEEEEEECCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHCCCCHHHH
TKMIGPAYQAIFGEGTSYRGEADILGIPYFTAYDPVRDMHGKTIGALFVGVKQSEYLARY
HHHCCHHHHHHHCCCCCCCCCCCEEECCCHHCCCCHHHHCCCEEEHHEEECCHHHHHHHH
DSINLKIRAISVMLAAIFVLMAVLLIQVRKKSEIAAQQQLAFQQLLLDTIPSPIFSKDAQ
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCC
GRYNLCNKAFQEYVGVPSEELLGKTVFDLWPRELAEQYQRMDQVIMESSGTQIYESQVKY
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ADGTLHDVLFHKAAFRDEKGTPAGLVGVILDITERKEAEMENSRLAAQMHQSRMVESLMI
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNHDLNTPLTPLFALLPMIEKQVDDPGLRRMLEICQQCANQIKGLAEKSLDLVRISSGR
HHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
PQLIPVRLAGTAEFACGEVADSLALRGVTCHNDIPADLWVLGSAEQLSLLFRNLLTNAAR
CCEEEEEECCCCHHHHHHHHHHHHHCCEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHH
YARANGHIVLGAAPMDGMVQVCVQDDGEGLDQEHLALVFNEFFKADPARQDVNTQGLGLA
HHCCCCCEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
ICKRIIANHDGRIWAESPGKGQGTTIFFTLNPAGDAPEEAKPDHPESYDI
HHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]