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The map label for this gene is zraS [C]

Identifier: 197117429

GI number: 197117429

Start: 1209265

End: 1211661

Strand: Reverse

Name: zraS [C]

Synonym: Gbem_1039

Alternate gene names: 197117429

Gene position: 1211661-1209265 (Counterclockwise)

Preceding gene: 197117430

Following gene: 197117428

Centisome position: 26.25

GC content: 65.5

Gene sequence:

>2397_bases
ATGAGCCGCCTTTCCATCGGACAACTCAAGGCGCGCATTGGCATCACCGTCGGGATCATCGTCGTCGCGGTATTGTGCAT
CTCCGGCCTGGGGGACACCGCGAAGATGTCGGTAGCTGCGGATGGCGGCGCGCAACTGCTGCTCGGCCACCCGTTGCAGC
ATTCGCTGCTGACGCTGGTTTTGTGCCTGCTGATCCTGGCCCTCACCACCCTTTTGTTCCGGCACCTGGACCGCTTGAAG
CAGGCGCAGCTCATGGTGGAGGGGCAGAAGGCGGAACTGGCGATAAAGGCCGCCCAGATCGACGCCGCCAACGACAGCAT
CCTGCAGGTCGACGAGGAGGGGCGGCTGCTCCATTTCAACCAGGCGCTCTGCCGGCTCACGGAGTACGATTGCGAAGAAC
TGGCGGGGATGCGGCTGCAGGAGATCGAACCGCCGGAATACGGCGGCCGGTTCGAGGCTATCGTCAACGGGCTGAGGGAA
TCGAAAGAGGCGACCTTCGAAAGCGTCTACCTCACCAAAGGTGGGGCTGCCGTTCCGGTCGAGGTTCATTCCCGCCTGCT
GGAGGGCGAGATGAAGACCCAGATACTCGCCATCGCCCGGGACATAACCGAGAGAAAGCGCAGCGAGCAAAGGGAGCGCT
GCCGGCTGAACACCCTGGAGCGGATAGCGACGGACGCCTCGCTCGACGAGCTTTTGGGGTGCGTGGTGAGGTACGTAGAG
CAGGAGATCCCGGGTGCGCTCTGCTCGGTCCTTTTGGTGGACGAATCCGGCACCAGGCTGCGCCACGGCGCCGCCCCATC
GCTTCCCGAGGCCTACAACCAGGCGGTGCACGGCCTGCGGATCGGCCAGGGGAAAGGGTCCTGCGGGACCGCCGCGTTCC
TCAGGCAGCGGGTAGTGGTGGAGGATCTGGAGTCGCACCCGTACTGGAACGGGTTCCAGCCCGCCCGGGATGCGGGGCTT
TCCGCCTGCTGGTCCGAGCCGGTCTTCGCCTCCAACGGCATCCTGCTCGGAACCCTGGCGGTCTATCACCGCGAGCCCCG
CGCCCCCGGCAACGACGACCTGCGCCTCATGGAGTCGGCGGCCCACCTGGCCGGGATTGCCATAGGAAGGGTCAGGGCCG
ACGACGGCAGGCGGGTTTTGGAGGATCAACTGCGCCACAGCCAGAAGATCGAGGCCGTGGGGCAACTGGCGGCGGGGGTG
GCACACGACTTCAACAACCTGCTGACGCCGATCATAGTCTACGCCGACATGCTGCAGCAGTACTGCCCCGCGGGAAGCAC
CCAGGCGCGCATGGTGGACGCCATGAGCCAGGCGGCCCAGAAGGCGGGGGATCTGACCCAGAAGCTCCTCTCCTTCGGGC
GCAAACAGGCGCTCCACGTGGAGCTATTGGACCTGAACGAGGTGATTGCCTCCTTCAGGGACATCCTGCGTGCCACCGCG
CGGGACAACGTCACCATCGACCTGCGGCTTTCCCCGGGGGCCGCCAAGGTGCAGGCGGACCGGGGGCAACTGGAGCAGGT
GCTTTTGAACCTCCTTTTGAACGCCCAGGACGCCATCGACGGGACCGGCTCGATCTGCGTCGAAACCGGGCACCTGATAC
TGGACGATGAGTTCCACAGGCAGCACCCGGTAGCGAAGCCCGGGCACTACATACTGCTTGCCTTTTCCGACGACGGCTGC
GGCATGGCGGAGGAGACGCTCAGGCACATGTACGAGCCGTTCTTCACCACCAAGGAGACCGGGCGCGGCACCGGCCTCGG
GCTCGCCACTGTGTACGGCATCGTCAAGCGCCATGGCGGCTGCATCGACGTCAAGAGCCGCCCCGGAGAGGGGACCAGGT
TCGGGATCTATCTCCCCGCCAGTTCCAGCAGCGCCGACCCCGTCACGGCCTCCCCCTCGCGCGCCGCGATCCCGCCCGCC
GCGGGAAAGGGGAAGACCATCCTCCTGGTCGAGGACAACGTCATGATCCGCGAGGTGGCAGAGGAGCTTCTCTCCTCCTT
CGGCTACGCGGTCCTGGCGGCCGAAAGCCCGGCCCGGGCGCTGGAACTTGCCAAGGAGCAGCAGAGGATAGACCTTTTGG
CGACCGACGTGGTCATGCCCGAGATGACCGGACCGGAGCTCTACGAAAAACTGCTTGAAAATTACCCGGGGCTGCCGGTA
CTGTACATCTCCGGCTACAGCGCGGGGCTCCTGCCGCTTGACGAGAGCCAGCGGCAGGACGCCATCTTCCTGGCCAAGCC
CTTCACCCTGGAACAGTTCATGGGCAAGATCGGGGAGATGCTCGGCTCGGACCTCCTCCTGGCGGTGCAGGCGCCGCTGG
ACGAGGCGATGGCCAGGCTGGTAACGAGAAGCTCGCGGCGAGTCAAGGACCCAGCGGATATATCCGCCACAGCATAA

Upstream 100 bases:

>100_bases
GCCCCGGCAAGGGGCAAGGGACCACCATCTTCTTTACGCTTAACCCCGCCGGCGATGCGCCGGAGGAAGCCAAACCCGAT
CATCCGGAGAGTTACGACAT

Downstream 100 bases:

>100_bases
AGGAAGGTGAACATGAATAACCGGATAATGATCGTGGACGACAACGAGTACGTACGGGCATCGGTCGAGATAATCTGCAA
CTCGGCGCAACTCGACCTGG

Product: sensor histidine kinase response receiver, PAS/GAF domain-containing protein

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 798; Mature: 797

Protein sequence:

>798_residues
MSRLSIGQLKARIGITVGIIVVAVLCISGLGDTAKMSVAADGGAQLLLGHPLQHSLLTLVLCLLILALTTLLFRHLDRLK
QAQLMVEGQKAELAIKAAQIDAANDSILQVDEEGRLLHFNQALCRLTEYDCEELAGMRLQEIEPPEYGGRFEAIVNGLRE
SKEATFESVYLTKGGAAVPVEVHSRLLEGEMKTQILAIARDITERKRSEQRERCRLNTLERIATDASLDELLGCVVRYVE
QEIPGALCSVLLVDESGTRLRHGAAPSLPEAYNQAVHGLRIGQGKGSCGTAAFLRQRVVVEDLESHPYWNGFQPARDAGL
SACWSEPVFASNGILLGTLAVYHREPRAPGNDDLRLMESAAHLAGIAIGRVRADDGRRVLEDQLRHSQKIEAVGQLAAGV
AHDFNNLLTPIIVYADMLQQYCPAGSTQARMVDAMSQAAQKAGDLTQKLLSFGRKQALHVELLDLNEVIASFRDILRATA
RDNVTIDLRLSPGAAKVQADRGQLEQVLLNLLLNAQDAIDGTGSICVETGHLILDDEFHRQHPVAKPGHYILLAFSDDGC
GMAEETLRHMYEPFFTTKETGRGTGLGLATVYGIVKRHGGCIDVKSRPGEGTRFGIYLPASSSSADPVTASPSRAAIPPA
AGKGKTILLVEDNVMIREVAEELLSSFGYAVLAAESPARALELAKEQQRIDLLATDVVMPEMTGPELYEKLLENYPGLPV
LYISGYSAGLLPLDESQRQDAIFLAKPFTLEQFMGKIGEMLGSDLLLAVQAPLDEAMARLVTRSSRRVKDPADISATA

Sequences:

>Translated_798_residues
MSRLSIGQLKARIGITVGIIVVAVLCISGLGDTAKMSVAADGGAQLLLGHPLQHSLLTLVLCLLILALTTLLFRHLDRLK
QAQLMVEGQKAELAIKAAQIDAANDSILQVDEEGRLLHFNQALCRLTEYDCEELAGMRLQEIEPPEYGGRFEAIVNGLRE
SKEATFESVYLTKGGAAVPVEVHSRLLEGEMKTQILAIARDITERKRSEQRERCRLNTLERIATDASLDELLGCVVRYVE
QEIPGALCSVLLVDESGTRLRHGAAPSLPEAYNQAVHGLRIGQGKGSCGTAAFLRQRVVVEDLESHPYWNGFQPARDAGL
SACWSEPVFASNGILLGTLAVYHREPRAPGNDDLRLMESAAHLAGIAIGRVRADDGRRVLEDQLRHSQKIEAVGQLAAGV
AHDFNNLLTPIIVYADMLQQYCPAGSTQARMVDAMSQAAQKAGDLTQKLLSFGRKQALHVELLDLNEVIASFRDILRATA
RDNVTIDLRLSPGAAKVQADRGQLEQVLLNLLLNAQDAIDGTGSICVETGHLILDDEFHRQHPVAKPGHYILLAFSDDGC
GMAEETLRHMYEPFFTTKETGRGTGLGLATVYGIVKRHGGCIDVKSRPGEGTRFGIYLPASSSSADPVTASPSRAAIPPA
AGKGKTILLVEDNVMIREVAEELLSSFGYAVLAAESPARALELAKEQQRIDLLATDVVMPEMTGPELYEKLLENYPGLPV
LYISGYSAGLLPLDESQRQDAIFLAKPFTLEQFMGKIGEMLGSDLLLAVQAPLDEAMARLVTRSSRRVKDPADISATA
>Mature_797_residues
SRLSIGQLKARIGITVGIIVVAVLCISGLGDTAKMSVAADGGAQLLLGHPLQHSLLTLVLCLLILALTTLLFRHLDRLKQ
AQLMVEGQKAELAIKAAQIDAANDSILQVDEEGRLLHFNQALCRLTEYDCEELAGMRLQEIEPPEYGGRFEAIVNGLRES
KEATFESVYLTKGGAAVPVEVHSRLLEGEMKTQILAIARDITERKRSEQRERCRLNTLERIATDASLDELLGCVVRYVEQ
EIPGALCSVLLVDESGTRLRHGAAPSLPEAYNQAVHGLRIGQGKGSCGTAAFLRQRVVVEDLESHPYWNGFQPARDAGLS
ACWSEPVFASNGILLGTLAVYHREPRAPGNDDLRLMESAAHLAGIAIGRVRADDGRRVLEDQLRHSQKIEAVGQLAAGVA
HDFNNLLTPIIVYADMLQQYCPAGSTQARMVDAMSQAAQKAGDLTQKLLSFGRKQALHVELLDLNEVIASFRDILRATAR
DNVTIDLRLSPGAAKVQADRGQLEQVLLNLLLNAQDAIDGTGSICVETGHLILDDEFHRQHPVAKPGHYILLAFSDDGCG
MAEETLRHMYEPFFTTKETGRGTGLGLATVYGIVKRHGGCIDVKSRPGEGTRFGIYLPASSSSADPVTASPSRAAIPPAA
GKGKTILLVEDNVMIREVAEELLSSFGYAVLAAESPARALELAKEQQRIDLLATDVVMPEMTGPELYEKLLENYPGLPVL
YISGYSAGLLPLDESQRQDAIFLAKPFTLEQFMGKIGEMLGSDLLLAVQAPLDEAMARLVTRSSRRVKDPADISATA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=262, Percent_Identity=33.969465648855, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=29.8387096774194, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI87081816, Length=273, Percent_Identity=27.4725274725275, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=233, Percent_Identity=32.1888412017167, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=25.3164556962025, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=29.004329004329, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1790300, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=25.3218884120172, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=25.609756097561, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86512; Mature: 86381

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSIGQLKARIGITVGIIVVAVLCISGLGDTAKMSVAADGGAQLLLGHPLQHSLLTLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHH
LCLLILALTTLLFRHLDRLKQAQLMVEGQKAELAIKAAQIDAANDSILQVDEEGRLLHFN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCCCEEEHH
QALCRLTEYDCEELAGMRLQEIEPPEYGGRFEAIVNGLRESKEATFESVYLTKGGAAVPV
HHHHHHHHCCHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCH
EVHSRLLEGEMKTQILAIARDITERKRSEQRERCRLNTLERIATDASLDELLGCVVRYVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QEIPGALCSVLLVDESGTRLRHGAAPSLPEAYNQAVHGLRIGQGKGSCGTAAFLRQRVVV
HHCCHHHEEEEEECCCCCEEECCCCCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHH
EDLESHPYWNGFQPARDAGLSACWSEPVFASNGILLGTLAVYHREPRAPGNDDLRLMESA
HHHHCCCCCCCCCHHHHHCCHHHCCCCCCCCCCEEEEHHHHHHCCCCCCCCCHHHHHHHH
AHLAGIAIGRVRADDGRRVLEDQLRHSQKIEAVGQLAAGVAHDFNNLLTPIIVYADMLQQ
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YCPAGSTQARMVDAMSQAAQKAGDLTQKLLSFGRKQALHVELLDLNEVIASFRDILRATA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHC
RDNVTIDLRLSPGAAKVQADRGQLEQVLLNLLLNAQDAIDGTGSICVETGHLILDDEFHR
CCCEEEEEEECCCCCEEECHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCEEECCHHHH
QHPVAKPGHYILLAFSDDGCGMAEETLRHMYEPFFTTKETGRGTGLGLATVYGIVKRHGG
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
CIDVKSRPGEGTRFGIYLPASSSSADPVTASPSRAAIPPAAGKGKTILLVEDNVMIREVA
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHH
EELLSSFGYAVLAAESPARALELAKEQQRIDLLATDVVMPEMTGPELYEKLLENYPGLPV
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEE
LYISGYSAGLLPLDESQRQDAIFLAKPFTLEQFMGKIGEMLGSDLLLAVQAPLDEAMARL
EEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
VTRSSRRVKDPADISATA
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLSIGQLKARIGITVGIIVVAVLCISGLGDTAKMSVAADGGAQLLLGHPLQHSLLTLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHHHHHHHH
LCLLILALTTLLFRHLDRLKQAQLMVEGQKAELAIKAAQIDAANDSILQVDEEGRLLHFN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEEECCCCCEEEHH
QALCRLTEYDCEELAGMRLQEIEPPEYGGRFEAIVNGLRESKEATFESVYLTKGGAAVPV
HHHHHHHHCCHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCH
EVHSRLLEGEMKTQILAIARDITERKRSEQRERCRLNTLERIATDASLDELLGCVVRYVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QEIPGALCSVLLVDESGTRLRHGAAPSLPEAYNQAVHGLRIGQGKGSCGTAAFLRQRVVV
HHCCHHHEEEEEECCCCCEEECCCCCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHH
EDLESHPYWNGFQPARDAGLSACWSEPVFASNGILLGTLAVYHREPRAPGNDDLRLMESA
HHHHCCCCCCCCCHHHHHCCHHHCCCCCCCCCCEEEEHHHHHHCCCCCCCCCHHHHHHHH
AHLAGIAIGRVRADDGRRVLEDQLRHSQKIEAVGQLAAGVAHDFNNLLTPIIVYADMLQQ
HHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YCPAGSTQARMVDAMSQAAQKAGDLTQKLLSFGRKQALHVELLDLNEVIASFRDILRATA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHC
RDNVTIDLRLSPGAAKVQADRGQLEQVLLNLLLNAQDAIDGTGSICVETGHLILDDEFHR
CCCEEEEEEECCCCCEEECHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCEEECCHHHH
QHPVAKPGHYILLAFSDDGCGMAEETLRHMYEPFFTTKETGRGTGLGLATVYGIVKRHGG
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCC
CIDVKSRPGEGTRFGIYLPASSSSADPVTASPSRAAIPPAAGKGKTILLVEDNVMIREVA
EEEECCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHH
EELLSSFGYAVLAAESPARALELAKEQQRIDLLATDVVMPEMTGPELYEKLLENYPGLPV
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEE
LYISGYSAGLLPLDESQRQDAIFLAKPFTLEQFMGKIGEMLGSDLLLAVQAPLDEAMARL
EEECCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
VTRSSRRVKDPADISATA
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA