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The map label for this gene is fbp [H]

Identifier: 197117395

GI number: 197117395

Start: 1163375

End: 1163842

Strand: Direct

Name: fbp [H]

Synonym: Gbem_1005

Alternate gene names: 197117395

Gene position: 1163375-1163842 (Clockwise)

Preceding gene: 197117394

Following gene: 197117396

Centisome position: 25.21

GC content: 61.97

Gene sequence:

>468_bases
ATGCGCAACGTAGAGAAGTTCATCGTCGTTTTGCTGCTCCTGGCTGCAGTAGCCATTCCCGCATGTTCCCAGAAAGAGGC
GAAGCCGGTGACGGAAAAGGCCGCCGAGAGCAAGGCCCCCGCCGGCGCGACGGTGACTGCTTCCGGGCTCTCCTATACCG
ATATCGTTAAAGGTACCGGCGCCGCTCCCACCTCCGGGAAGATGGTGACCGTGCATTACACGGGCGTCTTGGAAAACGGC
ACCAAGTTCGACAGCTCCGTCGATCGCGGCCAGCCCTTCAGCTTCCGCATCGGTGCGGGCGAGGTGATCCCCGGGTGGGA
CGAAGGTGTCATCTCCATGAAGGTCGGCGGCAAAAGAAAGCTGGTCATCCCGCCGCAGCTTGGTTACGGCGCGTCAGGGG
CCGGCGGGGTGATTCCCCCGAACGCCACGTTGATCTTCGATGTGGAACTGCTGGACGTAGGGAAGTAG

Upstream 100 bases:

>100_bases
TCGAACCCAAACTCAGAAGCGGTCTGTTCATCCACATGCTCGACTAGAAAAACTGCTGTTCTCACCGACAAGAAGAACAA
GACACAGACGGAGGAAGTAG

Downstream 100 bases:

>100_bases
AGCTTTTACGGCTCTTGCAATGACCTTTCGGTCCTGTAGATTTGTCATCTGTGTTTTTTGCCGGTGATCCTACAGGGTTT
CATTGCGAGGTGCCGCATGC

Product: peptidylprolyl cis-trans isomerase FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRNVEKFIVVLLLLAAVAIPACSQKEAKPVTEKAAESKAPAGATVTASGLSYTDIVKGTGAAPTSGKMVTVHYTGVLENG
TKFDSSVDRGQPFSFRIGAGEVIPGWDEGVISMKVGGKRKLVIPPQLGYGASGAGGVIPPNATLIFDVELLDVGK

Sequences:

>Translated_155_residues
MRNVEKFIVVLLLLAAVAIPACSQKEAKPVTEKAAESKAPAGATVTASGLSYTDIVKGTGAAPTSGKMVTVHYTGVLENG
TKFDSSVDRGQPFSFRIGAGEVIPGWDEGVISMKVGGKRKLVIPPQLGYGASGAGGVIPPNATLIFDVELLDVGK
>Mature_155_residues
MRNVEKFIVVLLLLAAVAIPACSQKEAKPVTEKAAESKAPAGATVTASGLSYTDIVKGTGAAPTSGKMVTVHYTGVLENG
TKFDSSVDRGQPFSFRIGAGEVIPGWDEGVISMKVGGKRKLVIPPQLGYGASGAGGVIPPNATLIFDVELLDVGK

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI4758380, Length=91, Percent_Identity=59.3406593406593, Blast_Score=117, Evalue=3e-27,
Organism=Homo sapiens, GI17149836, Length=91, Percent_Identity=58.2417582417582, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI4503725, Length=91, Percent_Identity=58.2417582417582, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI206725530, Length=90, Percent_Identity=55.5555555555556, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI17149844, Length=90, Percent_Identity=55.5555555555556, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI17149842, Length=90, Percent_Identity=55.5555555555556, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI4503729, Length=98, Percent_Identity=51.0204081632653, Blast_Score=102, Evalue=9e-23,
Organism=Homo sapiens, GI224809329, Length=102, Percent_Identity=50, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI224809327, Length=102, Percent_Identity=50, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI4758384, Length=102, Percent_Identity=50, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI224809331, Length=132, Percent_Identity=43.9393939393939, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI192448443, Length=115, Percent_Identity=42.6086956521739, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI33469985, Length=89, Percent_Identity=47.1910112359551, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI8923659, Length=91, Percent_Identity=49.4505494505495, Blast_Score=89, Evalue=1e-18,
Organism=Homo sapiens, GI4503727, Length=136, Percent_Identity=37.5, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI206725547, Length=93, Percent_Identity=46.2365591397849, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI31317231, Length=94, Percent_Identity=46.8085106382979, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI7706131, Length=86, Percent_Identity=38.3720930232558, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI17149839, Length=66, Percent_Identity=50, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI150010552, Length=120, Percent_Identity=32.5, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI87082390, Length=118, Percent_Identity=49.1525423728814, Blast_Score=108, Evalue=1e-25,
Organism=Escherichia coli, GI1789745, Length=133, Percent_Identity=48.8721804511278, Blast_Score=108, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71993519, Length=91, Percent_Identity=60.4395604395604, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17540882, Length=91, Percent_Identity=50.5494505494505, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17561782, Length=90, Percent_Identity=55.5555555555556, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561778, Length=113, Percent_Identity=39.8230088495575, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993555, Length=82, Percent_Identity=47.5609756097561, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17506167, Length=86, Percent_Identity=41.8604651162791, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17506169, Length=86, Percent_Identity=41.8604651162791, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324194, Length=100, Percent_Identity=59, Blast_Score=117, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6320727, Length=89, Percent_Identity=61.7977528089888, Blast_Score=108, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6323482, Length=118, Percent_Identity=42.3728813559322, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323566, Length=125, Percent_Identity=40, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281363946, Length=91, Percent_Identity=64.8351648351648, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI17352457, Length=91, Percent_Identity=64.8351648351648, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24655568, Length=106, Percent_Identity=57.5471698113208, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24647110, Length=127, Percent_Identity=46.4566929133858, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356629, Length=149, Percent_Identity=46.3087248322148, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24583150, Length=116, Percent_Identity=46.551724137931, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15927; Mature: 15927

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVEKFIVVLLLLAAVAIPACSQKEAKPVTEKAAESKAPAGATVTASGLSYTDIVKGTG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEHHCCCCC
AAPTSGKMVTVHYTGVLENGTKFDSSVDRGQPFSFRIGAGEVIPGWDEGVISMKVGGKRK
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEE
LVIPPQLGYGASGAGGVIPPNATLIFDVELLDVGK
EEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCC
>Mature Secondary Structure
MRNVEKFIVVLLLLAAVAIPACSQKEAKPVTEKAAESKAPAGATVTASGLSYTDIVKGTG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEHHCCCCC
AAPTSGKMVTVHYTGVLENGTKFDSSVDRGQPFSFRIGAGEVIPGWDEGVISMKVGGKRK
CCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEE
LVIPPQLGYGASGAGGVIPPNATLIFDVELLDVGK
EEECCCCCCCCCCCCCCCCCCCEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]