Definition Geobacter bemidjiensis Bem chromosome, complete genome.
Accession NC_011146
Length 4,615,150

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The map label for this gene is argC

Identifier: 197117304

GI number: 197117304

Start: 1075395

End: 1076435

Strand: Direct

Name: argC

Synonym: Gbem_0914

Alternate gene names: 197117304

Gene position: 1075395-1076435 (Clockwise)

Preceding gene: 197117303

Following gene: 197117305

Centisome position: 23.3

GC content: 63.3

Gene sequence:

>1041_bases
ATGATCAAGGTTGCCATCGTCGGGGCCAGCGGCTATACCGGCGTCGAACTTATCCGTATCCTGCATTCCCACCCCGAGGT
CGCCGTCACCTGCGTCACCTCCGAACAAAGCGCCGGGCGCCCGGTCAGCTCCGTCTTCCCGAGCCTGCGCGGCAGGTGCG
ACATCGTCCTGGAGAACCTGGAGCCGGTAGGGATCGCGGAGAAGGTCGACATCGTCTTCACGGCGCTGCCGCACAAGGCC
GCCATGGAAGTGGTGCCCACCTTCATGAAGATGGGCAAGGACGTCATCGATCTTTCCGCCGACTACCGCATTCACGATGC
GGATACCTACGGCAAATGGTACGAGCCGCACCTGAACCCCGAGCTTTTGCCGGAGGCTGTGTACGGCATCCCGGAACTGC
GCCGCGCCGAGATCGCCGAGGCCTCGCTGATCGCCAACCCCGGCTGCTACCCGACCAGTGTCATCCTGGGGCTTGCGCCG
CTTTTGAAGGGGAAGGTGATCGATCCCAGATCCATCATCGTGGACGCCGCGTCCGGCACCTCGGGTGCGGGGCGCGGAGC
CAAGGTGGATAACCTCTACTGCGAGGTGAACGAAGGGTTCCGCGCCTACGGCGTGGGGGGGGTGCACAGGCACATCCCGG
AGATAGAGCAGGAGCTGTCGCTTCTGGCAGGAAACCCGCTCAACATCACCTTCACCCCGCACCTGGTTCCCATGGACCGC
GGCATCCTCTCGACCATCTACTCCCAGCCGACCGGGAGCGTCAAGGCCGCCGACCTGATCGCTTTGTATCAGGCGTTCTA
TGACGGCGAGCCGTTCGTCAGGGTGTTGCCGGAAGGGGTTCTTCCCTCTACGGCACACGTCAGGGGCTCCAACTTCTGCG
ACATCGGCATCACAGTCGACCAGAGGACCGGGCGGGTCATCGTGATCTCCGCCATCGACAACTTGGTGAAAGGTGCTTCC
GGGCAGGCGGTGCAGAACATGAACCTGATGTGCGGCCTACCCGAGACCCTCGGGCTGGATCTCCTGCCGGTCTTTCCTTA
A

Upstream 100 bases:

>100_bases
CTGTCTTTTTCTCAGACATCCTCAGATTTCCTCCTTGTTAATGGTTTTGGTGTGCTAACATCGGGCTTATTTTTTTCCGT
TGTGAGAAGGGAGGCTTTTC

Downstream 100 bases:

>100_bases
AGTCAAAACCCTTGGCAAGGAGAACATCTGAGAGGATCTGAGAAAAGCAAAGACGGAGAGAAACAAAGCTCCAGCTTCGG
TTATTCTCAGACGTCCTCAG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIKVAIVGASGYTGVELIRILHSHPEVAVTCVTSEQSAGRPVSSVFPSLRGRCDIVLENLEPVGIAEKVDIVFTALPHKA
AMEVVPTFMKMGKDVIDLSADYRIHDADTYGKWYEPHLNPELLPEAVYGIPELRRAEIAEASLIANPGCYPTSVILGLAP
LLKGKVIDPRSIIVDAASGTSGAGRGAKVDNLYCEVNEGFRAYGVGGVHRHIPEIEQELSLLAGNPLNITFTPHLVPMDR
GILSTIYSQPTGSVKAADLIALYQAFYDGEPFVRVLPEGVLPSTAHVRGSNFCDIGITVDQRTGRVIVISAIDNLVKGAS
GQAVQNMNLMCGLPETLGLDLLPVFP

Sequences:

>Translated_346_residues
MIKVAIVGASGYTGVELIRILHSHPEVAVTCVTSEQSAGRPVSSVFPSLRGRCDIVLENLEPVGIAEKVDIVFTALPHKA
AMEVVPTFMKMGKDVIDLSADYRIHDADTYGKWYEPHLNPELLPEAVYGIPELRRAEIAEASLIANPGCYPTSVILGLAP
LLKGKVIDPRSIIVDAASGTSGAGRGAKVDNLYCEVNEGFRAYGVGGVHRHIPEIEQELSLLAGNPLNITFTPHLVPMDR
GILSTIYSQPTGSVKAADLIALYQAFYDGEPFVRVLPEGVLPSTAHVRGSNFCDIGITVDQRTGRVIVISAIDNLVKGAS
GQAVQNMNLMCGLPETLGLDLLPVFP
>Mature_346_residues
MIKVAIVGASGYTGVELIRILHSHPEVAVTCVTSEQSAGRPVSSVFPSLRGRCDIVLENLEPVGIAEKVDIVFTALPHKA
AMEVVPTFMKMGKDVIDLSADYRIHDADTYGKWYEPHLNPELLPEAVYGIPELRRAEIAEASLIANPGCYPTSVILGLAP
LLKGKVIDPRSIIVDAASGTSGAGRGAKVDNLYCEVNEGFRAYGVGGVHRHIPEIEQELSLLAGNPLNITFTPHLVPMDR
GILSTIYSQPTGSVKAADLIALYQAFYDGEPFVRVLPEGVLPSTAHVRGSNFCDIGITVDQRTGRVIVISAIDNLVKGAS
GQAVQNMNLMCGLPETLGLDLLPVFP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=345, Percent_Identity=40, Blast_Score=219, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6320913, Length=349, Percent_Identity=33.810888252149, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_GEOBB (B5EFN1)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137731.1
- ProteinModelPortal:   B5EFN1
- GeneID:   6783751
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0914
- HOGENOM:   HBG294213
- OMA:   GCFPTAS
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37029; Mature: 37029

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MIKVAIVGASGYTGVELIRILHSHPEVAVTCVTSEQSAGRPVSSVFPSLRGRCDIVLENL
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECC
EPVGIAEKVDIVFTALPHKAAMEVVPTFMKMGKDVIDLSADYRIHDADTYGKWYEPHLNP
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCCCCCCCCCH
ELLPEAVYGIPELRRAEIAEASLIANPGCYPTSVILGLAPLLKGKVIDPRSIIVDAASGT
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEEEECCCCC
SGAGRGAKVDNLYCEVNEGFRAYGVGGVHRHIPEIEQELSLLAGNPLNITFTPHLVPMDR
CCCCCCCEECEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
GILSTIYSQPTGSVKAADLIALYQAFYDGEPFVRVLPEGVLPSTAHVRGSNFCDIGITVD
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCEEEEEEEEE
QRTGRVIVISAIDNLVKGASGQAVQNMNLMCGLPETLGLDLLPVFP
CCCCCEEEEEEHHHHHCCCCCCCCCCCCEEECCCHHHCCCEEECCC
>Mature Secondary Structure
MIKVAIVGASGYTGVELIRILHSHPEVAVTCVTSEQSAGRPVSSVFPSLRGRCDIVLENL
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECC
EPVGIAEKVDIVFTALPHKAAMEVVPTFMKMGKDVIDLSADYRIHDADTYGKWYEPHLNP
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCCCCCCCCCCCCH
ELLPEAVYGIPELRRAEIAEASLIANPGCYPTSVILGLAPLLKGKVIDPRSIIVDAASGT
HHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHEEEECCCCC
SGAGRGAKVDNLYCEVNEGFRAYGVGGVHRHIPEIEQELSLLAGNPLNITFTPHLVPMDR
CCCCCCCEECEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCH
GILSTIYSQPTGSVKAADLIALYQAFYDGEPFVRVLPEGVLPSTAHVRGSNFCDIGITVD
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEECCCCEEEEEEEEE
QRTGRVIVISAIDNLVKGASGQAVQNMNLMCGLPETLGLDLLPVFP
CCCCCEEEEEEHHHHHCCCCCCCCCCCCEEECCCHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA