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The map label for this gene is hprK [H]

Identifier: 197117263

GI number: 197117263

Start: 1026568

End: 1027518

Strand: Direct

Name: hprK [H]

Synonym: Gbem_0871

Alternate gene names: 197117263

Gene position: 1026568-1027518 (Clockwise)

Preceding gene: 197117262

Following gene: 197117264

Centisome position: 22.24

GC content: 62.57

Gene sequence:

>951_bases
ATGAGCCTCAGCATCAAGGATCTTCTGGAAGACAAGGCCTACGGCCTGGACCTGCAGCTGCTCGGCGGCGAAGCGGGACT
GGCCAACCGTCTCTACAGTTCCCGCATCCAGAAACCGGGGCTCGCGCTCACCGGGTACACGGAGCACCTGCACCCGGATC
GGGTCCAGGTACTGGGCAACACCGAGATCTCCTACCTGAGCCAGATCCCCGAGGAAGTGGGGAGCCGGCACATCGAGAAG
CTCTGCAGCTACCCCATCGCCTGCTTCATCGTCACCAAGGGGCTCGATCCCCCCGAATTCCTTAAGAAGAGTGCCCAGGA
TGCCGGAATCCCGCTTCTGGGCACGCACCACCAGTCCTCCACCTTCATCTCCCTCATCACCAAGTTCCTGGAGGAGAGCC
TGCTCCCCTCGACCCACATCCACGGCGTGCTGGTAGACGTCCTGGGGGTGGGGGTGCTGCTCTTAGGCAAGAGCGGCATA
GGCAAGAGCGAGTGCGCCCTCGACCTGGTGATCCGCGGACACCGGCTGGTCGCCGACGACGTGATCCACATCAAGAAGAA
GATGCCGGCGGCGCTGGTCGGGCAGGCGGGAGAGTCGATCCAGTACCACATGGAGATCCGGGGCTTAGGGATCATCAACG
TCAAGGACCTCTACGGGGTCTCCTCCATCCGGGAAAAGAAGATCATCGACATGGTCCTGGAGCTCATGGAGTGGGACGCA
AGCCAGGAGTACGAGCGCCTGGGGATCGACGAGCCGATGAAGACCATCCTGGGCGTGGACCTGCCGCACCTGAAGATCCC
GGTACGTCCGGGCAGGAACCTCACCTCCATCATCGAGGTGGCCGCCAGGAACTTCCTGCTGAAGGGGATGGGGTACCACT
CCGCCCGGGAATTCCACGAAAAGCTCCTGGCCCGCCTGGAATTCCGGCCGTTGGGCAACGAGGTGGAATAG

Upstream 100 bases:

>100_bases
TAAAGGATAGGGAGGCGCCCCCCGTGGCGCCTCCCATCATCTACGGCCCCTTCTGGGGCTTTTCGCTTGCACGGGGGAAA
GGTCGACGCAATTGACAAGC

Downstream 100 bases:

>100_bases
CATGCGCATCGTCATCATAACCGGGCTCTCGGGCTCGGGAAAATCCACCGCCGTGCGCGCCCTGGAGGACGAGGGGTTCT
TCTGCCTGGACAACCTCCCG

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSLSIKDLLEDKAYGLDLQLLGGEAGLANRLYSSRIQKPGLALTGYTEHLHPDRVQVLGNTEISYLSQIPEEVGSRHIEK
LCSYPIACFIVTKGLDPPEFLKKSAQDAGIPLLGTHHQSSTFISLITKFLEESLLPSTHIHGVLVDVLGVGVLLLGKSGI
GKSECALDLVIRGHRLVADDVIHIKKKMPAALVGQAGESIQYHMEIRGLGIINVKDLYGVSSIREKKIIDMVLELMEWDA
SQEYERLGIDEPMKTILGVDLPHLKIPVRPGRNLTSIIEVAARNFLLKGMGYHSAREFHEKLLARLEFRPLGNEVE

Sequences:

>Translated_316_residues
MSLSIKDLLEDKAYGLDLQLLGGEAGLANRLYSSRIQKPGLALTGYTEHLHPDRVQVLGNTEISYLSQIPEEVGSRHIEK
LCSYPIACFIVTKGLDPPEFLKKSAQDAGIPLLGTHHQSSTFISLITKFLEESLLPSTHIHGVLVDVLGVGVLLLGKSGI
GKSECALDLVIRGHRLVADDVIHIKKKMPAALVGQAGESIQYHMEIRGLGIINVKDLYGVSSIREKKIIDMVLELMEWDA
SQEYERLGIDEPMKTILGVDLPHLKIPVRPGRNLTSIIEVAARNFLLKGMGYHSAREFHEKLLARLEFRPLGNEVE
>Mature_315_residues
SLSIKDLLEDKAYGLDLQLLGGEAGLANRLYSSRIQKPGLALTGYTEHLHPDRVQVLGNTEISYLSQIPEEVGSRHIEKL
CSYPIACFIVTKGLDPPEFLKKSAQDAGIPLLGTHHQSSTFISLITKFLEESLLPSTHIHGVLVDVLGVGVLLLGKSGIG
KSECALDLVIRGHRLVADDVIHIKKKMPAALVGQAGESIQYHMEIRGLGIINVKDLYGVSSIREKKIIDMVLELMEWDAS
QEYERLGIDEPMKTILGVDLPHLKIPVRPGRNLTSIIEVAARNFLLKGMGYHSAREFHEKLLARLEFRPLGNEVE

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 34918; Mature: 34787

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSIKDLLEDKAYGLDLQLLGGEAGLANRLYSSRIQKPGLALTGYTEHLHPDRVQVLGN
CCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCEEECCHHHCCCCCEEEECC
TEISYLSQIPEEVGSRHIEKLCSYPIACFIVTKGLDPPEFLKKSAQDAGIPLLGTHHQSS
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCHH
TFISLITKFLEESLLPSTHIHGVLVDVLGVGVLLLGKSGIGKSECALDLVIRGHRLVADD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCHHHHH
VIHIKKKMPAALVGQAGESIQYHMEIRGLGIINVKDLYGVSSIREKKIIDMVLELMEWDA
HHHHHHHCCHHHHCCCCCCEEEEEEEECCEEEEHHHHHCHHHHHHHHHHHHHHHHHHCCC
SQEYERLGIDEPMKTILGVDLPHLKIPVRPGRNLTSIIEVAARNFLLKGMGYHSAREFHE
CHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
KLLARLEFRPLGNEVE
HHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLSIKDLLEDKAYGLDLQLLGGEAGLANRLYSSRIQKPGLALTGYTEHLHPDRVQVLGN
CCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCCEEECCHHHCCCCCEEEECC
TEISYLSQIPEEVGSRHIEKLCSYPIACFIVTKGLDPPEFLKKSAQDAGIPLLGTHHQSS
CHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCHH
TFISLITKFLEESLLPSTHIHGVLVDVLGVGVLLLGKSGIGKSECALDLVIRGHRLVADD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCHHHHH
VIHIKKKMPAALVGQAGESIQYHMEIRGLGIINVKDLYGVSSIREKKIIDMVLELMEWDA
HHHHHHHCCHHHHCCCCCCEEEEEEEECCEEEEHHHHHCHHHHHHHHHHHHHHHHHHCCC
SQEYERLGIDEPMKTILGVDLPHLKIPVRPGRNLTSIIEVAARNFLLKGMGYHSAREFHE
CHHHHHCCCCHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
KLLARLEFRPLGNEVE
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA