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The map label for this gene is groES

Identifier: 197116648

GI number: 197116648

Start: 291147

End: 291437

Strand: Direct

Name: groES

Synonym: Gbem_0248

Alternate gene names: 197116648

Gene position: 291147-291437 (Clockwise)

Preceding gene: 197116647

Following gene: 197116649

Centisome position: 6.31

GC content: 57.04

Gene sequence:

>291_bases
ATGAATCTTAGACCGCTGCAGGACCGTATCATAGTGAAGAGGGTTGAGGAAGCTACCATGACCGCCGGTGGGCTTTATAT
CCCGGAAACCGCCAAAGAAAAGCCGCAGCAGGGCGAAGTGGTGGCAGTTGGCAACGGGAAGAGGGGCGAGGACGGCAAGG
TGTACCCGATCGACCTGAAGGTGGGTGACAAGGTGCTGTTCGGCAAGTACGCAGGAAGCGAAGTGAAGCTCGAAGGGGAG
GATTTCCTCATCATGCGCGAGGACGACATCCTCGGCGTCGTCGAGAAGTAA

Upstream 100 bases:

>100_bases
TGCTGTTTATATTTAGCAGGCCTTAGCACTCAGCTGTTTTGAGTGCTAATATTTTTTTCAATTACCGGAGATCGATGATC
TCGAAGAAAGGAGAGCAAGC

Downstream 100 bases:

>100_bases
TCACCGCCTCCCGGTCCGCCGGGGGAAGCAGTTTCGCCACCATTCATTAATTCCAAGGAGGATATACGTTATGGCAGCAA
AGATCATCAAGTTCGACCAG

Product: chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MNLRPLQDRIIVKRVEEATMTAGGLYIPETAKEKPQQGEVVAVGNGKRGEDGKVYPIDLKVGDKVLFGKYAGSEVKLEGE
DFLIMREDDILGVVEK

Sequences:

>Translated_96_residues
MNLRPLQDRIIVKRVEEATMTAGGLYIPETAKEKPQQGEVVAVGNGKRGEDGKVYPIDLKVGDKVLFGKYAGSEVKLEGE
DFLIMREDDILGVVEK
>Mature_96_residues
MNLRPLQDRIIVKRVEEATMTAGGLYIPETAKEKPQQGEVVAVGNGKRGEDGKVYPIDLKVGDKVLFGKYAGSEVKLEGE
DFLIMREDDILGVVEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=88, Percent_Identity=45.4545454545455, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI169210012, Length=88, Percent_Identity=43.1818181818182, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=51.0416666666667, Blast_Score=94, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=39.3617021276596, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324594, Length=97, Percent_Identity=44.3298969072165, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=42.5531914893617, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=41.9354838709677, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_GEOBB (B5E9Y1)

Other databases:

- EMBL:   CP001124
- RefSeq:   YP_002137075.1
- GeneID:   6783074
- GenomeReviews:   CP001124_GR
- KEGG:   gbm:Gbem_0248
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   CLSK2544507
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10590; Mature: 10590

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRPLQDRIIVKRVEEATMTAGGLYIPETAKEKPQQGEVVAVGNGKRGEDGKVYPIDLK
CCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
VGDKVLFGKYAGSEVKLEGEDFLIMREDDILGVVEK
ECCEEEEEECCCCEEEECCCCEEEEECCCEEEEECC
>Mature Secondary Structure
MNLRPLQDRIIVKRVEEATMTAGGLYIPETAKEKPQQGEVVAVGNGKRGEDGKVYPIDLK
CCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
VGDKVLFGKYAGSEVKLEGEDFLIMREDDILGVVEK
ECCEEEEEECCCCEEEECCCCEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA