| Definition | Geobacter bemidjiensis Bem chromosome, complete genome. |
|---|---|
| Accession | NC_011146 |
| Length | 4,615,150 |
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The map label for this gene is glmS [H]
Identifier: 197116490
GI number: 197116490
Start: 112025
End: 113854
Strand: Reverse
Name: glmS [H]
Synonym: Gbem_0090
Alternate gene names: 197116490
Gene position: 113854-112025 (Counterclockwise)
Preceding gene: 197116491
Following gene: 197116489
Centisome position: 2.47
GC content: 62.4
Gene sequence:
>1830_bases ATGTGCGGCATCGTAGGATTCACCGGGAGGCAGGAAGCCACCTCGATCATCATTGAAGGGCTGAGGAGACTGGAATACCG CGGTTACGATTCCGCCGGCATCTGCACCATCAGCGACGGCAAGGCAAGCATCAGGCGCAGCGAAGGGAAGCTCTCCAACC TGGAAAAGCTCCTGGCGGCGAGCCCGGTGACCGGGACCGTCGGCATAGGCCACACCCGCTGGGCCACCCACGGCCGCCCC TCCGAAATCAACGCACACCCGCACCAGGCGGGCCCCATCGTGGTGGTGCATAACGGCATCATCGAGAACTACCTGCAGCT GCGCGAGGAGCTGAAAGGGCAGGGGCACGTATTCAAGAGCGAGACCGACACCGAAGTAATCTCCCACCTGATCGACCAGC GCCTGAAGAGTTGCGACAGTTTCGAGCAGGCAGTGCGCGAGGCCCTGGCCGTATTGAAAGGGGCCTACGCCATCTGCATC GTGAGCGAGAACGACCCCGACGAGATGATCGCCGCCAAGCTCGGCTCCCCGATGGTAGTGGGGATCGGCGACGGCGAGTT CTACGTCGCCTCCGACATCCCGGCCATCCTTTCCCACACCCGCTCCATGATCTTCATGGAAGACGGCGAGATGGTCGTCT TCAAGGGGGGGAGTGCCACCTTCAGCAACGTCGCAGGGGGCGTGCTCAACAAGGTGCCGCGCCACATCGACTGGTCCGCG CACATGGCCGAGAAGGGCGGCTACAAACATTTCATGCTCAAGGAGATCTTCGAGCAGCCCCGCGCCGTGAGGGACACCAT CGCCGGGAGGCTTAGGGAAGAGCAAGGTGACGTCTATCTCGAAGACCTCTCCCTCAATGACGCAGCACTCAAAGGGATCA ACCGCATCTGCATCATCGCCTGCGGCACCTCGTGGCACGCCGCACTCGTCGGCAAGTTCCTGATCGAAGAGCACTGCCGG GTCCCGGTCGAAGTCGACATCGCCTCCGAGTTCCGCTACAGAAACCCCGTCGTCGACGAAAATACCCTGGTGATGCTGAT CTCCCAGTCCGGCGAGACCGCCGACACCCTGGCCGCCATGCGCGAGTCCAAACGCCGCGGCGGCAAGTGCGTCGCCATCT GCAACGTGGTCGACTCCTCCATCGCCCGCGAGGCCGACGGCGTCATCTACACCCACGCCGGTCCTGAGATCGGCGTCGCC TCCACCAAGGCCTTCGTAACCCAGCTGATCGCCCTCTACCTCTTCACCATCCGTCTCGGTCGCTCCCGCGAGGTCATGAG CCTGGAAGAGGGGAGGGATCTCATCGCCGCCGTGGTCCGGGTTCCGGCCCTGATGGAAGAGGCGCTGAAGCTGAACGAGC AGGTCGAGAAGGTTGCCAGGAACTACCTGCAGGCGCGCGACTTCCTCTATCTGGGGCGCGGCATGAACTACCCCATCGCC CTAGAAGGCGCGCTGAAATTGAAGGAGATCTCCTACATCCACGCCGAGGGGTACGCCGCCGGCGAGATGAAGCACGGTCC CATCGCGCTCATCGACGAGCACATGCCCGTAGTAGTGCTGGTCCCCAAGGGTCCCAACTACGACAAGGTCTTTTCCAATA TGGAAGAAGTCATCGCCCGCGGCGGTCGCGTCATCGCCGTCTGCAGCGAGGGTGACCAGGAAGTAAAAGACAAGGTCGAG GTGGCGCTGGAGATTCCCGAAGACGGCTGCAACGTAAGCCCGTTGATCCTCTCCATCCCCATGCAGCTTCTGGCTTACCA CGTAGCGGTCCTCAAGGGGACCGACGTCGACCAGCCGAGAAACCTGGCGAAAAGCGTCACCGTCGAATAA
Upstream 100 bases:
>100_bases CTGAGGAAAAAATAAAACTGTAACTACCCTGCCCAAGATGGTAATCTGTAACGTCTTTGGCGGCAGACCGCGAACTTAAT TAGCGAAACACGGAGTCAAA
Downstream 100 bases:
>100_bases ACAGCCAGAAAACCAGAAGGATAATAGACACGAAAGTGCCAGTTGCGATCCGCAGCTGGCACTTTTTTTTCTCCTCTACG ATTCTCCGTCTCCGCATCAG
Product: glucosamine--fructose-6-phosphate aminotransferase
Products: NA
Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]
Number of amino acids: Translated: 609; Mature: 609
Protein sequence:
>609_residues MCGIVGFTGRQEATSIIIEGLRRLEYRGYDSAGICTISDGKASIRRSEGKLSNLEKLLAASPVTGTVGIGHTRWATHGRP SEINAHPHQAGPIVVVHNGIIENYLQLREELKGQGHVFKSETDTEVISHLIDQRLKSCDSFEQAVREALAVLKGAYAICI VSENDPDEMIAAKLGSPMVVGIGDGEFYVASDIPAILSHTRSMIFMEDGEMVVFKGGSATFSNVAGGVLNKVPRHIDWSA HMAEKGGYKHFMLKEIFEQPRAVRDTIAGRLREEQGDVYLEDLSLNDAALKGINRICIIACGTSWHAALVGKFLIEEHCR VPVEVDIASEFRYRNPVVDENTLVMLISQSGETADTLAAMRESKRRGGKCVAICNVVDSSIAREADGVIYTHAGPEIGVA STKAFVTQLIALYLFTIRLGRSREVMSLEEGRDLIAAVVRVPALMEEALKLNEQVEKVARNYLQARDFLYLGRGMNYPIA LEGALKLKEISYIHAEGYAAGEMKHGPIALIDEHMPVVVLVPKGPNYDKVFSNMEEVIARGGRVIAVCSEGDQEVKDKVE VALEIPEDGCNVSPLILSIPMQLLAYHVAVLKGTDVDQPRNLAKSVTVE
Sequences:
>Translated_609_residues MCGIVGFTGRQEATSIIIEGLRRLEYRGYDSAGICTISDGKASIRRSEGKLSNLEKLLAASPVTGTVGIGHTRWATHGRP SEINAHPHQAGPIVVVHNGIIENYLQLREELKGQGHVFKSETDTEVISHLIDQRLKSCDSFEQAVREALAVLKGAYAICI VSENDPDEMIAAKLGSPMVVGIGDGEFYVASDIPAILSHTRSMIFMEDGEMVVFKGGSATFSNVAGGVLNKVPRHIDWSA HMAEKGGYKHFMLKEIFEQPRAVRDTIAGRLREEQGDVYLEDLSLNDAALKGINRICIIACGTSWHAALVGKFLIEEHCR VPVEVDIASEFRYRNPVVDENTLVMLISQSGETADTLAAMRESKRRGGKCVAICNVVDSSIAREADGVIYTHAGPEIGVA STKAFVTQLIALYLFTIRLGRSREVMSLEEGRDLIAAVVRVPALMEEALKLNEQVEKVARNYLQARDFLYLGRGMNYPIA LEGALKLKEISYIHAEGYAAGEMKHGPIALIDEHMPVVVLVPKGPNYDKVFSNMEEVIARGGRVIAVCSEGDQEVKDKVE VALEIPEDGCNVSPLILSIPMQLLAYHVAVLKGTDVDQPRNLAKSVTVE >Mature_609_residues MCGIVGFTGRQEATSIIIEGLRRLEYRGYDSAGICTISDGKASIRRSEGKLSNLEKLLAASPVTGTVGIGHTRWATHGRP SEINAHPHQAGPIVVVHNGIIENYLQLREELKGQGHVFKSETDTEVISHLIDQRLKSCDSFEQAVREALAVLKGAYAICI VSENDPDEMIAAKLGSPMVVGIGDGEFYVASDIPAILSHTRSMIFMEDGEMVVFKGGSATFSNVAGGVLNKVPRHIDWSA HMAEKGGYKHFMLKEIFEQPRAVRDTIAGRLREEQGDVYLEDLSLNDAALKGINRICIIACGTSWHAALVGKFLIEEHCR VPVEVDIASEFRYRNPVVDENTLVMLISQSGETADTLAAMRESKRRGGKCVAICNVVDSSIAREADGVIYTHAGPEIGVA STKAFVTQLIALYLFTIRLGRSREVMSLEEGRDLIAAVVRVPALMEEALKLNEQVEKVARNYLQARDFLYLGRGMNYPIA LEGALKLKEISYIHAEGYAAGEMKHGPIALIDEHMPVVVLVPKGPNYDKVFSNMEEVIARGGRVIAVCSEGDQEVKDKVE VALEIPEDGCNVSPLILSIPMQLLAYHVAVLKGTDVDQPRNLAKSVTVE
Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]
COG id: COG0449
COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 SIS domains [H]
Homologues:
Organism=Homo sapiens, GI4826742, Length=684, Percent_Identity=38.5964912280702, Blast_Score=449, Evalue=1e-126, Organism=Homo sapiens, GI205277386, Length=684, Percent_Identity=35.8187134502924, Blast_Score=432, Evalue=1e-121, Organism=Escherichia coli, GI1790167, Length=613, Percent_Identity=47.4714518760196, Blast_Score=553, Evalue=1e-158, Organism=Escherichia coli, GI1788651, Length=233, Percent_Identity=27.8969957081545, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17539970, Length=440, Percent_Identity=39.3181818181818, Blast_Score=315, Evalue=4e-86, Organism=Caenorhabditis elegans, GI17532899, Length=440, Percent_Identity=39.0909090909091, Blast_Score=308, Evalue=4e-84, Organism=Caenorhabditis elegans, GI17532897, Length=440, Percent_Identity=39.0909090909091, Blast_Score=308, Evalue=5e-84, Organism=Saccharomyces cerevisiae, GI6322745, Length=443, Percent_Identity=39.2776523702032, Blast_Score=302, Evalue=1e-82, Organism=Saccharomyces cerevisiae, GI6323731, Length=436, Percent_Identity=30.9633027522936, Blast_Score=215, Evalue=1e-56, Organism=Saccharomyces cerevisiae, GI6323730, Length=208, Percent_Identity=39.4230769230769, Blast_Score=130, Evalue=5e-31, Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=38.6861313868613, Blast_Score=465, Evalue=1e-131,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000583 - InterPro: IPR017932 - InterPro: IPR005855 - InterPro: IPR001347 [H]
Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]
EC number: =2.6.1.16 [H]
Molecular weight: Translated: 66514; Mature: 66514
Theoretical pI: Translated: 5.73; Mature: 5.73
Prosite motif: PS00443 GATASE_TYPE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MCGIVGFTGRQEATSIIIEGLRRLEYRGYDSAGICTISDGKASIRRSEGKLSNLEKLLAA CCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHC SPVTGTVGIGHTRWATHGRPSEINAHPHQAGPIVVVHNGIIENYLQLREELKGQGHVFKS CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCEECC ETDTEVISHLIDQRLKSCDSFEQAVREALAVLKGAYAICIVSENDPDEMIAAKLGSPMVV CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEEE GIGDGEFYVASDIPAILSHTRSMIFMEDGEMVVFKGGSATFSNVAGGVLNKVPRHIDWSA EECCCCEEEECCCHHHHHCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCHH HMAEKGGYKHFMLKEIFEQPRAVRDTIAGRLREEQGDVYLEDLSLNDAALKGINRICIIA HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCEEEEEE CGTSWHAALVGKFLIEEHCRVPVEVDIASEFRYRNPVVDENTLVMLISQSGETADTLAAM ECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHH RESKRRGGKCVAICNVVDSSIAREADGVIYTHAGPEIGVASTKAFVTQLIALYLFTIRLG HHHHHCCCCEEEEEEHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC RSREVMSLEEGRDLIAAVVRVPALMEEALKLNEQVEKVARNYLQARDFLYLGRGMNYPIA CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEE LEGALKLKEISYIHAEGYAAGEMKHGPIALIDEHMPVVVLVPKGPNYDKVFSNMEEVIAR ECCCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHC GGRVIAVCSEGDQEVKDKVEVALEIPEDGCNVSPLILSIPMQLLAYHVAVLKGTDVDQPR CCCEEEEECCCCHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH NLAKSVTVE HHHHHCCCC >Mature Secondary Structure MCGIVGFTGRQEATSIIIEGLRRLEYRGYDSAGICTISDGKASIRRSEGKLSNLEKLLAA CCCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHC SPVTGTVGIGHTRWATHGRPSEINAHPHQAGPIVVVHNGIIENYLQLREELKGQGHVFKS CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHCCCCCEECC ETDTEVISHLIDQRLKSCDSFEQAVREALAVLKGAYAICIVSENDPDEMIAAKLGSPMVV CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEEE GIGDGEFYVASDIPAILSHTRSMIFMEDGEMVVFKGGSATFSNVAGGVLNKVPRHIDWSA EECCCCEEEECCCHHHHHCCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCCHH HMAEKGGYKHFMLKEIFEQPRAVRDTIAGRLREEQGDVYLEDLSLNDAALKGINRICIIA HHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCEEEEEE CGTSWHAALVGKFLIEEHCRVPVEVDIASEFRYRNPVVDENTLVMLISQSGETADTLAAM ECCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHH RESKRRGGKCVAICNVVDSSIAREADGVIYTHAGPEIGVASTKAFVTQLIALYLFTIRLG HHHHHCCCCEEEEEEHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCC RSREVMSLEEGRDLIAAVVRVPALMEEALKLNEQVEKVARNYLQARDFLYLGRGMNYPIA CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCEE LEGALKLKEISYIHAEGYAAGEMKHGPIALIDEHMPVVVLVPKGPNYDKVFSNMEEVIAR ECCCEEEEHEEEEEECCCCCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHC GGRVIAVCSEGDQEVKDKVEVALEIPEDGCNVSPLILSIPMQLLAYHVAVLKGTDVDQPR CCCEEEEECCCCHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH NLAKSVTVE HHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA