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The map label for this gene is coxC [H]

Identifier: 197116444

GI number: 197116444

Start: 54495

End: 55094

Strand: Direct

Name: coxC [H]

Synonym: Gbem_0044

Alternate gene names: 197116444

Gene position: 54495-55094 (Clockwise)

Preceding gene: 197116443

Following gene: 197116445

Centisome position: 1.18

GC content: 57.0

Gene sequence:

>600_bases
ATGAGTCATGCGGAAAAGGACAGTTTTGGTGCAAAGCTCGGCATGTGGTTGTTCCTGTTCACAGAGATGCTTCTCTTTGG
CGGGGTCTTCATCCTCTACTCGGTCTACCTGACCCGGTACCCGAAGGAGTTCGGCCTGGGGGGGCACCAGCTGGACCTGG
TCTTTGGCGCGACCAACACGGTGGTGCTTCTGACCAGCTCACTCTTCGCCGCCATGTCGGTCACCGCCATCAAGCGGGGG
GCGAAGCAGCTCACCTTGGGGCTTCTCTCCGGCACCATCGGCTGCGCGCTCATCTTCTTGTTCATCAAGTACCTGGAGTG
GAGCGCCAAATTCCATCACGGCATCTATCCGAACTCCCCCAAGCTGATCGCGGGGCCGCCGGGAGAATCGATCTTCTTCA
GCCTGTACTACCTCACCACCGGGCTGCACGGGATCCATGTCATCATCGGCGGGATCCTGATGACCTGGACAGCAGTCATG
GTGCAAAAGGGAATGCTCAACAGCGCTGACAACGTCACCCTGGAAAACGTGACACTGTACTGGCATCTGGTTGACTTGGT
CTGGATCTTCATCTTCCCGCTCTACTACTTGATTCTTTAG

Upstream 100 bases:

>100_bases
CGCTTGAGTGGAGCATCGCGACGCCTCCTCCCACCGAAAATTTTGATGAGGACCCGGTGGTGACCCACGGGCCGTACGAG
TTCAAGGGGGCAGGCATTCC

Downstream 100 bases:

>100_bases
AAACAGATAAAGATTGAGATTGAGACAAACCTAAAAGCAACAGCGTAAAACGGAAGCAGTAATACTGGGTTTACTTAATC
TTAATCTCAATCTTAATCTA

Product: cytochrome c oxidase subunit III

Products: ferricytochrome c; H2O

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSHAEKDSFGAKLGMWLFLFTEMLLFGGVFILYSVYLTRYPKEFGLGGHQLDLVFGATNTVVLLTSSLFAAMSVTAIKRG
AKQLTLGLLSGTIGCALIFLFIKYLEWSAKFHHGIYPNSPKLIAGPPGESIFFSLYYLTTGLHGIHVIIGGILMTWTAVM
VQKGMLNSADNVTLENVTLYWHLVDLVWIFIFPLYYLIL

Sequences:

>Translated_199_residues
MSHAEKDSFGAKLGMWLFLFTEMLLFGGVFILYSVYLTRYPKEFGLGGHQLDLVFGATNTVVLLTSSLFAAMSVTAIKRG
AKQLTLGLLSGTIGCALIFLFIKYLEWSAKFHHGIYPNSPKLIAGPPGESIFFSLYYLTTGLHGIHVIIGGILMTWTAVM
VQKGMLNSADNVTLENVTLYWHLVDLVWIFIFPLYYLIL
>Mature_198_residues
SHAEKDSFGAKLGMWLFLFTEMLLFGGVFILYSVYLTRYPKEFGLGGHQLDLVFGATNTVVLLTSSLFAAMSVTAIKRGA
KQLTLGLLSGTIGCALIFLFIKYLEWSAKFHHGIYPNSPKLIAGPPGESIFFSLYYLTTGLHGIHVIIGGILMTWTAVMV
QKGMLNSADNVTLENVTLYWHLVDLVWIFIFPLYYLIL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1786633, Length=198, Percent_Identity=28.7878787878788, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00115 COX1; PF00510 COX3 [H]

EC number: 1.9.3.1

Molecular weight: Translated: 22184; Mature: 22052

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAEKDSFGAKLGMWLFLFTEMLLFGGVFILYSVYLTRYPKEFGLGGHQLDLVFGATNT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCH
VVLLTSSLFAAMSVTAIKRGAKQLTLGLLSGTIGCALIFLFIKYLEWSAKFHHGIYPNSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KLIAGPPGESIFFSLYYLTTGLHGIHVIIGGILMTWTAVMVQKGMLNSADNVTLENVTLY
EEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHH
WHLVDLVWIFIFPLYYLIL
HHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SHAEKDSFGAKLGMWLFLFTEMLLFGGVFILYSVYLTRYPKEFGLGGHQLDLVFGATNT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCCH
VVLLTSSLFAAMSVTAIKRGAKQLTLGLLSGTIGCALIFLFIKYLEWSAKFHHGIYPNSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
KLIAGPPGESIFFSLYYLTTGLHGIHVIIGGILMTWTAVMVQKGMLNSADNVTLENVTLY
EEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHH
WHLVDLVWIFIFPLYYLIL
HHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrocytochrome c; O2

Specific reaction: 4 ferrocytochrome c + O2 = 4 ferricytochrome c + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]