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The map label for this gene is nadA [H]

Identifier: 197106068

GI number: 197106068

Start: 2997188

End: 2998273

Strand: Direct

Name: nadA [H]

Synonym: PHZ_c2607

Alternate gene names: 197106068

Gene position: 2997188-2998273 (Clockwise)

Preceding gene: 197106067

Following gene: 197106069

Centisome position: 75.0

GC content: 68.23

Gene sequence:

>1086_bases
ATGGCCGCCGACGGTTCGCAGTTCGCCTTCACGCCTGAGGTCGAGGCCGAGACCCTTCCCGCATGGGAGAAGGTGAAGCG
CCACGTCACGCCGATGGAATGGCGCGCGCACGCCCCGCTGATCGCCGAGATCAACCGGCTGAAGCGCGAGAAGAACGCCG
TCATCCTCGCCCACAACTACATGACGCCCGAGATCTTCCACGGCGTCGGCGACTACGTGGGCGACAGCCTGGGGCTGGCG
AAGGAAGCGGCCAAGTCCGACGCTGCGGTGATCGTTCAGGCGGGCGTCCACTTCATGGCCGAGACGTCCAAGATCCTCAG
CCCCGAGAAGCGCGTCCTGATCCCCGACCTGCGGGCCGGCTGCTCGCTGGCCAGCTCGATCACCGGCGCGGACGTGCGCC
TGATCAAGCAGCGCTATCCCGGCCTGCCGGTGGTCACCTACGTCAACACCACCGCCGACGTGAAGGCGGAGACCGACATC
TGCTGCACCAGCGCCAACGCCGTGCAGGTGGTGGAGGAAGCCGCCAGGCTGTGGGGCGTCGACAAGGTGGTCCTGATCCC
CGACGAGTTCCTCGCCCGCAACGTCGCCCGCCAGACCGACATCGGCATCATCGCCTGGAAGGGCCGTTGCGAGGTGCACG
AGCGCTTCACCGCCGAGGACATCCTCGAGATCAAGGCCGCCTATCCGGGCGCCGAGGTCCTGGCCCACCCCGAGTGCCCG
GCCGAGGTGCTGGAGGTCTCGGACTTCGCCGGCTCGACGGCGGCGATGAACGACTACGTGCTGCAGAGGAAGCCCAAGCG
CGTGGTTCTGATCACCGAGTGCTCGATGGCCGACAACGTGGCCGCCGACGCGCATGGCACCGAGTTCGTGCGCCCCTGCA
ATCTGTGCCCCCACATGAAGCGGATCAGCCTGGAGAACATCTACGAGGCCCTGCTCCACGACCGGCACGAAGTGACCGTC
GACCCGGCGATCGCCGAGCGCGCCCGCCTGGCGGTCCAGCGGATGATCGACCTGCCGCCGCCGGCCAGGCCCGCCCGCTA
CGACCTCGTGAAGGCCCGCCACCACGTCGACGTGGAGCTGATCTGA

Upstream 100 bases:

>100_bases
GGTTTTGCTCCGATTGAGCAAAAGTGATCGCGCCACGGGCATCCGGGCGCCTTTTTAAAAGCCCCAGTAATGCTCACTAT
GAGCATAAGGGAGGGACGAC

Downstream 100 bases:

>100_bases
TGGCCCTGCTCCGCCAAGGCTGCGCAGGGCATGGCCCCGATCCTTCGAAGCGCCCGAAGGGAGCGAACTAGGATGGCCGA
CCGCATCCGCCACGACGGGA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAADGSQFAFTPEVEAETLPAWEKVKRHVTPMEWRAHAPLIAEINRLKREKNAVILAHNYMTPEIFHGVGDYVGDSLGLA
KEAAKSDAAVIVQAGVHFMAETSKILSPEKRVLIPDLRAGCSLASSITGADVRLIKQRYPGLPVVTYVNTTADVKAETDI
CCTSANAVQVVEEAARLWGVDKVVLIPDEFLARNVARQTDIGIIAWKGRCEVHERFTAEDILEIKAAYPGAEVLAHPECP
AEVLEVSDFAGSTAAMNDYVLQRKPKRVVLITECSMADNVAADAHGTEFVRPCNLCPHMKRISLENIYEALLHDRHEVTV
DPAIAERARLAVQRMIDLPPPARPARYDLVKARHHVDVELI

Sequences:

>Translated_361_residues
MAADGSQFAFTPEVEAETLPAWEKVKRHVTPMEWRAHAPLIAEINRLKREKNAVILAHNYMTPEIFHGVGDYVGDSLGLA
KEAAKSDAAVIVQAGVHFMAETSKILSPEKRVLIPDLRAGCSLASSITGADVRLIKQRYPGLPVVTYVNTTADVKAETDI
CCTSANAVQVVEEAARLWGVDKVVLIPDEFLARNVARQTDIGIIAWKGRCEVHERFTAEDILEIKAAYPGAEVLAHPECP
AEVLEVSDFAGSTAAMNDYVLQRKPKRVVLITECSMADNVAADAHGTEFVRPCNLCPHMKRISLENIYEALLHDRHEVTV
DPAIAERARLAVQRMIDLPPPARPARYDLVKARHHVDVELI
>Mature_360_residues
AADGSQFAFTPEVEAETLPAWEKVKRHVTPMEWRAHAPLIAEINRLKREKNAVILAHNYMTPEIFHGVGDYVGDSLGLAK
EAAKSDAAVIVQAGVHFMAETSKILSPEKRVLIPDLRAGCSLASSITGADVRLIKQRYPGLPVVTYVNTTADVKAETDIC
CTSANAVQVVEEAARLWGVDKVVLIPDEFLARNVARQTDIGIIAWKGRCEVHERFTAEDILEIKAAYPGAEVLAHPECPA
EVLEVSDFAGSTAAMNDYVLQRKPKRVVLITECSMADNVAADAHGTEFVRPCNLCPHMKRISLENIYEALLHDRHEVTVD
PAIAERARLAVQRMIDLPPPARPARYDLVKARHHVDVELI

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=325, Percent_Identity=34.4615384615385, Blast_Score=177, Evalue=7e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 39785; Mature: 39654

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAADGSQFAFTPEVEAETLPAWEKVKRHVTPMEWRAHAPLIAEINRLKREKNAVILAHNY
CCCCCCCEEECCCCCCCCCCHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHCCEEEEEECC
MTPEIFHGVGDYVGDSLGLAKEAAKSDAAVIVQAGVHFMAETSKILSPEKRVLIPDLRAG
CCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEECCCHHHH
CSLASSITGADVRLIKQRYPGLPVVTYVNTTADVKAETDICCTSANAVQVVEEAARLWGV
HHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCC
DKVVLIPDEFLARNVARQTDIGIIAWKGRCEVHERFTAEDILEIKAAYPGAEVLAHPECP
CEEEECCHHHHHHHHHHHCCCEEEEECCCCHHHHHCCHHHHHHHHHCCCCHHEEECCCCC
AEVLEVSDFAGSTAAMNDYVLQRKPKRVVLITECSMADNVAADAHGTEFVRPCNLCPHMK
HHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHH
RISLENIYEALLHDRHEVTVDPAIAERARLAVQRMIDLPPPARPARYDLVKARHHVDVEL
HCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEE
I
C
>Mature Secondary Structure 
AADGSQFAFTPEVEAETLPAWEKVKRHVTPMEWRAHAPLIAEINRLKREKNAVILAHNY
CCCCCCEEECCCCCCCCCCHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHCCEEEEEECC
MTPEIFHGVGDYVGDSLGLAKEAAKSDAAVIVQAGVHFMAETSKILSPEKRVLIPDLRAG
CCHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEECCCHHHH
CSLASSITGADVRLIKQRYPGLPVVTYVNTTADVKAETDICCTSANAVQVVEEAARLWGV
HHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHCCC
DKVVLIPDEFLARNVARQTDIGIIAWKGRCEVHERFTAEDILEIKAAYPGAEVLAHPECP
CEEEECCHHHHHHHHHHHCCCEEEEECCCCHHHHHCCHHHHHHHHHCCCCHHEEECCCCC
AEVLEVSDFAGSTAAMNDYVLQRKPKRVVLITECSMADNVAADAHGTEFVRPCNLCPHMK
HHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHH
RISLENIYEALLHDRHEVTVDPAIAERARLAVQRMIDLPPPARPARYDLVKARHHVDVEL
HCCHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEE
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA