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The map label for this gene is yybO [H]

Identifier: 197106024

GI number: 197106024

Start: 2944141

End: 2945529

Strand: Reverse

Name: yybO [H]

Synonym: PHZ_c2563

Alternate gene names: 197106024

Gene position: 2945529-2944141 (Counterclockwise)

Preceding gene: 197106025

Following gene: 197106022

Centisome position: 73.71

GC content: 66.09

Gene sequence:

>1389_bases
ATGACGGCAGGTACGGCGGCGCAGGGGAAGAGCGGCGAGACAAAGGCGTCCCCAGAGGCCTGGTGGATGCTGGCGGTTCT
GTTCGGCCTCTACACGTTCTCGTTCATCGACCGGTACGTGATCACGATCATGGTGCCGGAGATCAAGCAGAGCCTCGGCC
TTAGCGACTTCGAGATGGGGATCATCCTCGGCCCGGCGTTCGCTATCGTCTATTCGATCTGCGGCCTGCCCCTCGGCTGG
GTCGCCGACCGGTTTCCGCGCCGATGGGTCGTCTTCATCGGTGTCGCGGTCTTCGGTCTCGCCACCGCGGCCTCGGGCCT
GGCGGGCTCCTTCGTGGGCCTGTTCCTCGCCCGCATGTTCATCGGCATCGGCGAGGCTTCCCTCTCGCCCGCCGCCTACT
CGCTCATGGCGGACAAGTTCCCGAGAAACCTCTTCGGCACCGCCAGCGCGGTCTACAACACCGCCGCCAAGGTCGGCACC
GCCAGCGCGCTGACGCTCGGCGGTCTTGCCATGGGGCTGGCGGCCGGAATGGAGCTGCAGGTCCCAGGCCTGGGGGCGAT
GGAGCCCTGGCGCATGGTGTTCCTGATGGTCGGCGTGCCGGTGATGCTGCTGAGTCTGCTGGTGTTCACCTTCAGCGAAC
CGCCGAGGACCGCTATCCCAAAGCTCGCCGACGGCGAGAAGGCGCACAACATCCTGAGCTTCCTCAATGCGGAGAAAAGG
GTGCTGGCGCCGATGCTCCTCGGCTTCTCGCTCATGGCGGTCTGTTCGTTCGCCCTGGCCTCATGGGCGCCAACCTACAT
CGCGCGACGGTTCGAATGGGGGCCCGCCCAGTACGGACCAATCCTCGGAGCCGTCAGCCTCGCCGCCGCGCTTACGCTCG
TCTTCAAGGGGGCCATCGTCGACTGGCTCTATACGCGGGGCGGCAAGGACGCCTACGTGCGCTTCTACACCTGGCTTCTG
ATGGGCACGGCGCCCATCGCGGTCGTGACCTTCTTCATTCCCGATCCGCTGCTGTTCATGGCCTGCTACGGCGTCATCCA
AGTGGTGGCGCTGCCGACCATCGTCTTTCTTTCCGCCGCAGTTCAGCTGATCGTGCCGGGTCATCTGCGCGGTCAGATGA
CGGCCGTGTTCCTCTTCTGCCTGACGGTGGTGGGCGGATCCACTGGGCCCGTCCTCGTGGCGAGCCTGACCGACTTCGTG
TTCCGCGACGACGCCATGGTGGGCTACTCCATGGCGATCGTTCTTTGCTCGGCCATTCCGCTCGCTCTGGCGCTGCTGCG
CTATTCGCTCCGCCCCCTGCGGGAGGCGGTGCTCAAGGTGGAGGCGCGCCAGGAGGCGGAGATCGTCTGGAGCAGCGATG
CGGCGCCCGCAACGTCCGGGAGGCATTGA

Upstream 100 bases:

>100_bases
ACGACTCGCAGGCTGGGCTCGGGCTCCGGCCCGGCAAACTGAATTCAGAGCTCAAGAACATAAGCGCTCGCATCGCAGCG
AGCCGGTGAGGAAACGGCAG

Downstream 100 bases:

>100_bases
CCCAGAAGGGGGTGCGGGGGCGCCGCGGCGCCCGCCGGTCCTACTCGAGAACGTCTAGGACTGTGGCCTTTCCGACGGCG
CCGACCCAGAACGAGCCCGC

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTAGTAAQGKSGETKASPEAWWMLAVLFGLYTFSFIDRYVITIMVPEIKQSLGLSDFEMGIILGPAFAIVYSICGLPLGW
VADRFPRRWVVFIGVAVFGLATAASGLAGSFVGLFLARMFIGIGEASLSPAAYSLMADKFPRNLFGTASAVYNTAAKVGT
ASALTLGGLAMGLAAGMELQVPGLGAMEPWRMVFLMVGVPVMLLSLLVFTFSEPPRTAIPKLADGEKAHNILSFLNAEKR
VLAPMLLGFSLMAVCSFALASWAPTYIARRFEWGPAQYGPILGAVSLAAALTLVFKGAIVDWLYTRGGKDAYVRFYTWLL
MGTAPIAVVTFFIPDPLLFMACYGVIQVVALPTIVFLSAAVQLIVPGHLRGQMTAVFLFCLTVVGGSTGPVLVASLTDFV
FRDDAMVGYSMAIVLCSAIPLALALLRYSLRPLREAVLKVEARQEAEIVWSSDAAPATSGRH

Sequences:

>Translated_462_residues
MTAGTAAQGKSGETKASPEAWWMLAVLFGLYTFSFIDRYVITIMVPEIKQSLGLSDFEMGIILGPAFAIVYSICGLPLGW
VADRFPRRWVVFIGVAVFGLATAASGLAGSFVGLFLARMFIGIGEASLSPAAYSLMADKFPRNLFGTASAVYNTAAKVGT
ASALTLGGLAMGLAAGMELQVPGLGAMEPWRMVFLMVGVPVMLLSLLVFTFSEPPRTAIPKLADGEKAHNILSFLNAEKR
VLAPMLLGFSLMAVCSFALASWAPTYIARRFEWGPAQYGPILGAVSLAAALTLVFKGAIVDWLYTRGGKDAYVRFYTWLL
MGTAPIAVVTFFIPDPLLFMACYGVIQVVALPTIVFLSAAVQLIVPGHLRGQMTAVFLFCLTVVGGSTGPVLVASLTDFV
FRDDAMVGYSMAIVLCSAIPLALALLRYSLRPLREAVLKVEARQEAEIVWSSDAAPATSGRH
>Mature_461_residues
TAGTAAQGKSGETKASPEAWWMLAVLFGLYTFSFIDRYVITIMVPEIKQSLGLSDFEMGIILGPAFAIVYSICGLPLGWV
ADRFPRRWVVFIGVAVFGLATAASGLAGSFVGLFLARMFIGIGEASLSPAAYSLMADKFPRNLFGTASAVYNTAAKVGTA
SALTLGGLAMGLAAGMELQVPGLGAMEPWRMVFLMVGVPVMLLSLLVFTFSEPPRTAIPKLADGEKAHNILSFLNAEKRV
LAPMLLGFSLMAVCSFALASWAPTYIARRFEWGPAQYGPILGAVSLAAALTLVFKGAIVDWLYTRGGKDAYVRFYTWLLM
GTAPIAVVTFFIPDPLLFMACYGVIQVVALPTIVFLSAAVQLIVPGHLRGQMTAVFLFCLTVVGGSTGPVLVASLTDFVF
RDDAMVGYSMAIVLCSAIPLALALLRYSLRPLREAVLKVEARQEAEIVWSSDAAPATSGRH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=287, Percent_Identity=27.8745644599303, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI14042968, Length=287, Percent_Identity=27.8745644599303, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI215490102, Length=366, Percent_Identity=24.5901639344262, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI2367379, Length=381, Percent_Identity=24.9343832020997, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789152, Length=160, Percent_Identity=29.375, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=24.4131455399061, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789515, Length=329, Percent_Identity=23.4042553191489, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539092, Length=268, Percent_Identity=26.1194029850746, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17557872, Length=306, Percent_Identity=25.1633986928105, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193209775, Length=258, Percent_Identity=25.1937984496124, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24654041, Length=290, Percent_Identity=24.4827586206897, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654037, Length=290, Percent_Identity=24.1379310344828, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24654039, Length=258, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864456, Length=258, Percent_Identity=25.5813953488372, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654044, Length=258, Percent_Identity=25.1937984496124, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640209, Length=359, Percent_Identity=25.3481894150418, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49318; Mature: 49187

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAGTAAQGKSGETKASPEAWWMLAVLFGLYTFSFIDRYVITIMVPEIKQSLGLSDFEMG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCCCCCCCHH
IILGPAFAIVYSICGLPLGWVADRFPRRWVVFIGVAVFGLATAASGLAGSFVGLFLARMF
HHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIGEASLSPAAYSLMADKFPRNLFGTASAVYNTAAKVGTASALTLGGLAMGLAAGMELQ
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEE
VPGLGAMEPWRMVFLMVGVPVMLLSLLVFTFSEPPRTAIPKLADGEKAHNILSFLNAEKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
VLAPMLLGFSLMAVCSFALASWAPTYIARRFEWGPAQYGPILGAVSLAAALTLVFKGAIV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DWLYTRGGKDAYVRFYTWLLMGTAPIAVVTFFIPDPLLFMACYGVIQVVALPTIVFLSAA
HHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VQLIVPGHLRGQMTAVFLFCLTVVGGSTGPVLVASLTDFVFRDDAMVGYSMAIVLCSAIP
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LALALLRYSLRPLREAVLKVEARQEAEIVWSSDAAPATSGRH
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
TAGTAAQGKSGETKASPEAWWMLAVLFGLYTFSFIDRYVITIMVPEIKQSLGLSDFEMG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHCCCCCCCHH
IILGPAFAIVYSICGLPLGWVADRFPRRWVVFIGVAVFGLATAASGLAGSFVGLFLARMF
HHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGIGEASLSPAAYSLMADKFPRNLFGTASAVYNTAAKVGTASALTLGGLAMGLAAGMELQ
HHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEE
VPGLGAMEPWRMVFLMVGVPVMLLSLLVFTFSEPPRTAIPKLADGEKAHNILSFLNAEKR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHH
VLAPMLLGFSLMAVCSFALASWAPTYIARRFEWGPAQYGPILGAVSLAAALTLVFKGAIV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DWLYTRGGKDAYVRFYTWLLMGTAPIAVVTFFIPDPLLFMACYGVIQVVALPTIVFLSAA
HHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VQLIVPGHLRGQMTAVFLFCLTVVGGSTGPVLVASLTDFVFRDDAMVGYSMAIVLCSAIP
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LALALLRYSLRPLREAVLKVEARQEAEIVWSSDAAPATSGRH
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]