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The map label for this gene is fabG [H]

Identifier: 197105964

GI number: 197105964

Start: 2869912

End: 2870592

Strand: Reverse

Name: fabG [H]

Synonym: PHZ_c2503

Alternate gene names: 197105964

Gene position: 2870592-2869912 (Counterclockwise)

Preceding gene: 197105965

Following gene: 197105963

Centisome position: 71.83

GC content: 74.89

Gene sequence:

>681_bases
ATGGCGGGACGCATCATCGCAATCACCGGCGCGGCCGGCGTGCTGGGCCAGGCCGTGGTGAAGGCCGCCGCCGCCCAGGG
CGCGCGGCTGGCGCTCATCGACCATGCCAAGGCGTGTCCGGGCCCCGAGGGCGCGTTCGTGCAGACGGGCGTGGACCTGA
CCGACGCCGTGCAGGCCTCGGCCGCCATGGCCGCCGCCGGCGAGCGCCTCGGCGGGCTGGACGCGCTCCTGAACATCGCC
GGGGGGTTCACCTGGGAGAAGCTGGAGGGCGGCGATCCCGCGAGCTGGGCCGCCATGCACCGGCTCAACGTCGTCACGGC
CGCCAACGCCTGCCGCGCAGCGATCCCGCACCTGAAGGCCAGCGCCGCGGGCCGGATCGTCAATGTGGGCTCGGCCGCCG
CGCTCAAGGCCGGCGCCGGCATGGGCCCCTATGCGGCCGCCAAGTCGGGGGTCCACAGCCTGACCCAGGCGCTGGCCGAG
GAGCTGAAGGCCGACGGGGTGACGGTCAACGCCGTGCTGCCCTCGATCATCGACACCCCCACGAACCGCGCCGACATGCC
GGACGCGGACTTCTCGGCCTGGGTGGCGCCGGACGACCTGGCCGCCGTGATCCTGTTCCTGGCGAGCGAGGCGGCCAGCG
CGGTGACGGGCGCCCTGATGCCGGTGACCGGCCGCGTCTGA

Upstream 100 bases:

>100_bases
CGGGGGTCCAGTCACGCAGGCGCTTGCGGGCTCGCCCCGAAGTGCGGTGCTTATGGATGGCCGGGACCAAGCCCGGCCAT
GACGATTCTGGGAGTCTGGG

Downstream 100 bases:

>100_bases
GGCGCGGCGGCTGTCACGAGTTCTTAGCAGTCGCAGCTTACGGCCGATCCTACGCGTCCAAGCGTAGGGGATAGTTCAAT
GATCAAGTCACGTTCGCGGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAGRIIAITGAAGVLGQAVVKAAAAQGARLALIDHAKACPGPEGAFVQTGVDLTDAVQASAAMAAAGERLGGLDALLNIA
GGFTWEKLEGGDPASWAAMHRLNVVTAANACRAAIPHLKASAAGRIVNVGSAAALKAGAGMGPYAAAKSGVHSLTQALAE
ELKADGVTVNAVLPSIIDTPTNRADMPDADFSAWVAPDDLAAVILFLASEAASAVTGALMPVTGRV

Sequences:

>Translated_226_residues
MAGRIIAITGAAGVLGQAVVKAAAAQGARLALIDHAKACPGPEGAFVQTGVDLTDAVQASAAMAAAGERLGGLDALLNIA
GGFTWEKLEGGDPASWAAMHRLNVVTAANACRAAIPHLKASAAGRIVNVGSAAALKAGAGMGPYAAAKSGVHSLTQALAE
ELKADGVTVNAVLPSIIDTPTNRADMPDADFSAWVAPDDLAAVILFLASEAASAVTGALMPVTGRV
>Mature_225_residues
AGRIIAITGAAGVLGQAVVKAAAAQGARLALIDHAKACPGPEGAFVQTGVDLTDAVQASAAMAAAGERLGGLDALLNIAG
GFTWEKLEGGDPASWAAMHRLNVVTAANACRAAIPHLKASAAGRIVNVGSAAALKAGAGMGPYAAAKSGVHSLTQALAEE
LKADGVTVNAVLPSIIDTPTNRADMPDADFSAWVAPDDLAAVILFLASEAASAVTGALMPVTGRV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI208973246, Length=235, Percent_Identity=31.9148936170213, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=26.3374485596708, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=23.2, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI40254992, Length=234, Percent_Identity=25.6410256410256, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=27.8481012658228, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=25.2066115702479, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082160, Length=243, Percent_Identity=27.5720164609054, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=237, Percent_Identity=28.2700421940928, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788459, Length=184, Percent_Identity=30.9782608695652, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=25.8064516129032, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=243, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=30.4526748971193, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=28.2786885245902, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=242, Percent_Identity=27.6859504132231, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=168, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554872, Length=226, Percent_Identity=28.3185840707965, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=224, Percent_Identity=25.4464285714286, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI62472128, Length=233, Percent_Identity=33.4763948497854, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17647337, Length=233, Percent_Identity=33.4763948497854, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI62472140, Length=233, Percent_Identity=33.4763948497854, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=27.2357723577236, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644337, Length=247, Percent_Identity=29.9595141700405, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=27.7551020408163, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 22281; Mature: 22149

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRIIAITGAAGVLGQAVVKAAAAQGARLALIDHAKACPGPEGAFVQTGVDLTDAVQAS
CCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCHHHHHHHH
AAMAAAGERLGGLDALLNIAGGFTWEKLEGGDPASWAAMHRLNVVTAANACRAAIPHLKA
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAGRIVNVGSAAALKAGAGMGPYAAAKSGVHSLTQALAEELKADGVTVNAVLPSIIDTP
HHCCCEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCC
TNRADMPDADFSAWVAPDDLAAVILFLASEAASAVTGALMPVTGRV
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AGRIIAITGAAGVLGQAVVKAAAAQGARLALIDHAKACPGPEGAFVQTGVDLTDAVQAS
CCCEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEECCCCHHHHHHHH
AAMAAAGERLGGLDALLNIAGGFTWEKLEGGDPASWAAMHRLNVVTAANACRAAIPHLKA
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAAGRIVNVGSAAALKAGAGMGPYAAAKSGVHSLTQALAEELKADGVTVNAVLPSIIDTP
HHCCCEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCC
TNRADMPDADFSAWVAPDDLAAVILFLASEAASAVTGALMPVTGRV
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]