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The map label for this gene is mhpD

Identifier: 197105914

GI number: 197105914

Start: 2805224

End: 2806093

Strand: Direct

Name: mhpD

Synonym: PHZ_c2453

Alternate gene names: NA

Gene position: 2805224-2806093 (Clockwise)

Preceding gene: 197105910

Following gene: 197105915

Centisome position: 70.2

GC content: 74.6

Gene sequence:

>870_bases
GTGACCGTGCCGGCGGCCGAGACCGCGTCCCGCTTCGACCCTGAGGCCATCGCCCGTGCGTTCGTCGCCGCCCGCCGGGC
GGCCCGCGCGCTGCCCGGCTTCCCGGGGCCGATCCCCGCCGACATGGCCGCCGGGTACCGCGTGCAGGAGGCCGCCATCG
GGCTGTGGCCGGACGAGATCGCCGGCTGGAAGGTCGGCCGGATTCCCGAGGACCTGCAGGCGCAGCTAGGCGCCGACCGG
GTGATGGGTCCCGTCTTCCGCGCCAACGTCTGGCAGGCCGATCCGGCCCGGGCCACGCCCCTTCCGGTGATCCCCGGCGG
CTTCGCGGCCGTCGAGGCCGAGTACGTCTTCCGCATCGGCCGGGACGCGCCCGCCGACAAGACCGACTGGACGCCGGCCG
AGGCGCTGGAGATCGTCGAGGAGATGCTGACCGGCGTCGAGCTGGCCGGCAGTCCCCTGGCCACCATCAACGTGCTGGGC
CCCCGGGTCGTGGCCTCGGATTTCGGCAACAACGCGGGCCTGATCCTCGGTCAGCCGATCCCCGGCTGGCGCGAGCGGCC
CGACGCTATCCCGGCCTGCGAGGCCTATGTGGACGGCGTCCTCGACGGCCGCGGGACTCCCCAATCCGTGCCGGGCGGCC
CCGCCGCCTCGCTGGCCTTCCTGCTGCGCGCCGCGGCGCTGCGCGGTCGGCCCCTCAAGGCCGGCCAGCTGGTGACGACC
GGCGCGGCCAGCGGCATCCATGACATCGAGGCCGGCCAATCGGCCCGAATCGTCTTCGGCGACCTGCAGGAGATCCGCTG
CCAGGCGGTCACCGCGGCGCCGGAGGACCAGGGAGGAAACAACGATGGCCACAGCCGCCGAACGGACTGA

Upstream 100 bases:

>100_bases
CACAATGTGCGCGCCGACCCGCCCCCGGCCCGCGCCGCGGGGCGTCCAAGAACGACCAGACGCCGACGTCACGGACGAAC
CGGCCGGAGGACGACAGGAA

Downstream 100 bases:

>100_bases
CGCCGCAGCCCCGCCCGCCGTCGTGGGCCGCTACCGCTGGGTGGTGGTGGGGCTCCTCTTTGCGGCGATGGTGATCAACT
ACGTCGATCGCCAGACCATC

Product: 2-keto-4-pentenoate hydratase

Products: 2-oxopent-4-enoate; H2O

Alternate protein names: 2-Keto-4-Pentenoate Hydratase-Like Protein; Fumarylacetoacetate Hydrolase; 2-Keto-4-Pentenoate Hydratase Family Protein

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MTVPAAETASRFDPEAIARAFVAARRAARALPGFPGPIPADMAAGYRVQEAAIGLWPDEIAGWKVGRIPEDLQAQLGADR
VMGPVFRANVWQADPARATPLPVIPGGFAAVEAEYVFRIGRDAPADKTDWTPAEALEIVEEMLTGVELAGSPLATINVLG
PRVVASDFGNNAGLILGQPIPGWRERPDAIPACEAYVDGVLDGRGTPQSVPGGPAASLAFLLRAAALRGRPLKAGQLVTT
GAASGIHDIEAGQSARIVFGDLQEIRCQAVTAAPEDQGGNNDGHSRRTD

Sequences:

>Translated_289_residues
MTVPAAETASRFDPEAIARAFVAARRAARALPGFPGPIPADMAAGYRVQEAAIGLWPDEIAGWKVGRIPEDLQAQLGADR
VMGPVFRANVWQADPARATPLPVIPGGFAAVEAEYVFRIGRDAPADKTDWTPAEALEIVEEMLTGVELAGSPLATINVLG
PRVVASDFGNNAGLILGQPIPGWRERPDAIPACEAYVDGVLDGRGTPQSVPGGPAASLAFLLRAAALRGRPLKAGQLVTT
GAASGIHDIEAGQSARIVFGDLQEIRCQAVTAAPEDQGGNNDGHSRRTD
>Mature_288_residues
TVPAAETASRFDPEAIARAFVAARRAARALPGFPGPIPADMAAGYRVQEAAIGLWPDEIAGWKVGRIPEDLQAQLGADRV
MGPVFRANVWQADPARATPLPVIPGGFAAVEAEYVFRIGRDAPADKTDWTPAEALEIVEEMLTGVELAGSPLATINVLGP
RVVASDFGNNAGLILGQPIPGWRERPDAIPACEAYVDGVLDGRGTPQSVPGGPAASLAFLLRAAALRGRPLKAGQLVTTG
AASGIHDIEAGQSARIVFGDLQEIRCQAVTAAPEDQGGNNDGHSRRTD

Specific function: Unknown

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.80

Molecular weight: Translated: 30147; Mature: 30016

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVPAAETASRFDPEAIARAFVAARRAARALPGFPGPIPADMAAGYRVQEAAIGLWPDEI
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEHHHHHCCCHHHH
AGWKVGRIPEDLQAQLGADRVMGPVFRANVWQADPARATPLPVIPGGFAAVEAEYVFRIG
CCCCCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEC
RDAPADKTDWTPAEALEIVEEMLTGVELAGSPLATINVLGPRVVASDFGNNAGLILGQPI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCEEECCCC
PGWRERPDAIPACEAYVDGVLDGRGTPQSVPGGPAASLAFLLRAAALRGRPLKAGQLVTT
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEC
GAASGIHDIEAGQSARIVFGDLQEIRCQAVTAAPEDQGGNNDGHSRRTD
CCCCCCCHHCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVPAAETASRFDPEAIARAFVAARRAARALPGFPGPIPADMAAGYRVQEAAIGLWPDEI
CCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEHHHHHCCCHHHH
AGWKVGRIPEDLQAQLGADRVMGPVFRANVWQADPARATPLPVIPGGFAAVEAEYVFRIG
CCCCCCCCCHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEC
RDAPADKTDWTPAEALEIVEEMLTGVELAGSPLATINVLGPRVVASDFGNNAGLILGQPI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHCCCCCCEEECCCC
PGWRERPDAIPACEAYVDGVLDGRGTPQSVPGGPAASLAFLLRAAALRGRPLKAGQLVTT
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEC
GAASGIHDIEAGQSARIVFGDLQEIRCQAVTAAPEDQGGNNDGHSRRTD
CCCCCCCHHCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxy-2-oxopentanoate

Specific reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA