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The map label for this gene is bioD

Identifier: 197105841

GI number: 197105841

Start: 2698365

End: 2699069

Strand: Direct

Name: bioD

Synonym: PHZ_c2380

Alternate gene names: 197105841

Gene position: 2698365-2699069 (Clockwise)

Preceding gene: 197105840

Following gene: 197105843

Centisome position: 67.52

GC content: 69.22

Gene sequence:

>705_bases
ATGAGCCGTTACTTTGTGGCCGGGTCCCATACGGATGTCGGCAAGACCTTCGTCAGCTGTCAGCTGATCCGCGCCGAACG
GGCGGCGGGCCGAAGCGCGACCGCCTTCAAGCCGGTTCTGAGCGGCTTCGATCCTGACCGCGCGGAGGCCAGCGACGCCG
GCCAGCTTCTCGAGGCGCTCGGGGAGCCGGTGACGTCCACCCGTCTGGACCGGATCTCGCCCCTGCGCTTCATCGCCCCC
CTGGCGCCGCCCTCGGCGGCAAGGCTCGAGGGCGTTGTCCTCACCCGAGACAGGCTCCTCACGCTCTCGAACGCCTGGCT
GTCGAGAACGGACGCGGACCTGAACCTGCTGGAAGGCGCCGGCGGGGTGATGTCGCCGATCGCCGAAGACGCCACCAACC
TCGACCTGATGACGGGTCTGGGCCTGCCGGTGATCCTGGTCGGCGGCTCCTACCTTGGGGCGATCAGCCATACGCTCACC
GCACTGGAAGTACTGCGCACGCGCAGCCTGACCATCGCCGCGGTCGTCGTGTCCCAGTCAGCCGATCCGGAAGCGCCGGA
CTTCGCCGAGACGGTCGAACTCACCCGTCAGCATGCCGGAGGCGTTCCGATCTTCGCGGCGCCCCGCAACGGTCATGCTG
CGTGGGCTTCGGCATTGACCGAGGCCCTGGCCGCCCGGCGACGGCTGAGGACCAGCGCAGCCTGA

Upstream 100 bases:

>100_bases
TTCCGGCCAACACCGCGCGGCTGCGCATCGCCTGCAGCGCCCTGCACACCGAAAGCCAGATCGATGACCTGGCGGCCGCG
CTTCAGCCCTGGATGCAGGC

Downstream 100 bases:

>100_bases
CGCAAGCCAGCGACGCTGGAGCCTCCGGCCGATCAGCGCCGCGTTGAAGGCTCGAGCAGCGGGGCGTCGCGCGCAAGAAA
CGTGTTCAGTACGAAGCTCG

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MSRYFVAGSHTDVGKTFVSCQLIRAERAAGRSATAFKPVLSGFDPDRAEASDAGQLLEALGEPVTSTRLDRISPLRFIAP
LAPPSAARLEGVVLTRDRLLTLSNAWLSRTDADLNLLEGAGGVMSPIAEDATNLDLMTGLGLPVILVGGSYLGAISHTLT
ALEVLRTRSLTIAAVVVSQSADPEAPDFAETVELTRQHAGGVPIFAAPRNGHAAWASALTEALAARRRLRTSAA

Sequences:

>Translated_234_residues
MSRYFVAGSHTDVGKTFVSCQLIRAERAAGRSATAFKPVLSGFDPDRAEASDAGQLLEALGEPVTSTRLDRISPLRFIAP
LAPPSAARLEGVVLTRDRLLTLSNAWLSRTDADLNLLEGAGGVMSPIAEDATNLDLMTGLGLPVILVGGSYLGAISHTLT
ALEVLRTRSLTIAAVVVSQSADPEAPDFAETVELTRQHAGGVPIFAAPRNGHAAWASALTEALAARRRLRTSAA
>Mature_233_residues
SRYFVAGSHTDVGKTFVSCQLIRAERAAGRSATAFKPVLSGFDPDRAEASDAGQLLEALGEPVTSTRLDRISPLRFIAPL
APPSAARLEGVVLTRDRLLTLSNAWLSRTDADLNLLEGAGGVMSPIAEDATNLDLMTGLGLPVILVGGSYLGAISHTLTA
LEVLRTRSLTIAAVVVSQSADPEAPDFAETVELTRQHAGGVPIFAAPRNGHAAWASALTEALAARRRLRTSAA

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family

Homologues:

Organism=Escherichia coli, GI1786995, Length=218, Percent_Identity=33.4862385321101, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BIOD_PHEZH (B4RFX6)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131218.1
- ProteinModelPortal:   B4RFX6
- GeneID:   6791901
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2380
- HOGENOM:   HBG650065
- OMA:   PQMERIE
- ProtClustDB:   CLSK890484
- HAMAP:   MF_00336
- InterPro:   IPR004472
- InterPro:   IPR002586
- PIRSF:   PIRSF006755
- TIGRFAMs:   TIGR00347

Pfam domain/function: PF01656 CbiA

EC number: =6.3.3.3

Molecular weight: Translated: 24536; Mature: 24405

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYFVAGSHTDVGKTFVSCQLIRAERAAGRSATAFKPVLSGFDPDRAEASDAGQLLEAL
CCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
GEPVTSTRLDRISPLRFIAPLAPPSAARLEGVVLTRDRLLTLSNAWLSRTDADLNLLEGA
CCCHHHHHHHHCCCHHHHCCCCCCCHHHHCEEEEEHHHHHHHHHHHHHCCCCCCHHHHCC
GGVMSPIAEDATNLDLMTGLGLPVILVGGSYLGAISHTLTALEVLRTRSLTIAAVVVSQS
CCHHHHHHHHHCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
ADPEAPDFAETVELTRQHAGGVPIFAAPRNGHAAWASALTEALAARRRLRTSAA
CCCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRYFVAGSHTDVGKTFVSCQLIRAERAAGRSATAFKPVLSGFDPDRAEASDAGQLLEAL
CCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
GEPVTSTRLDRISPLRFIAPLAPPSAARLEGVVLTRDRLLTLSNAWLSRTDADLNLLEGA
CCCHHHHHHHHCCCHHHHCCCCCCCHHHHCEEEEEHHHHHHHHHHHHHCCCCCCHHHHCC
GGVMSPIAEDATNLDLMTGLGLPVILVGGSYLGAISHTLTALEVLRTRSLTIAAVVVSQS
CCHHHHHHHHHCCCHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECC
ADPEAPDFAETVELTRQHAGGVPIFAAPRNGHAAWASALTEALAARRRLRTSAA
CCCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA