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The map label for this gene is btuB [H]

Identifier: 197105833

GI number: 197105833

Start: 2688413

End: 2690914

Strand: Reverse

Name: btuB [H]

Synonym: PHZ_c2372

Alternate gene names: 197105833

Gene position: 2690914-2688413 (Counterclockwise)

Preceding gene: 197105834

Following gene: 197105832

Centisome position: 67.34

GC content: 63.11

Gene sequence:

>2502_bases
ATGGCGCAGGAATGCAATCGGGGCGGGCGGGTTCGGCTCTTCCGGAACACCTCAGCCGCAGCGATTTTCGCGGGGGCGGT
GTTCGCCTCATCGGCTCATGCCCAGGCGGCTGACCCCAGCGGGCAAGGCGGGGCGGATACCTTGACTGAAGTGGTTGTCA
CGGGTGTCCGCGGGCAGCCTCGCTCCAAGCTGGATAGCCCGACTCCGATCGACGTCCTCTCGGGGGAGGAGATTGCGAAG
GGCGGTCACGCCAACCTCTACCAGGACATGCAACTGCAGGTCCCGTCGTTCAACTACACCACGAAGGCGGGTTCGGGCAC
TTCAAGCGCTATTCTGACCGGCGGCCTGCGAGGCCTGAATCCTGATCACACCCTTGTGCTGGTGAATGGTCTGCGCCGTC
ACCACACGTCACTGATCAACGTCGGCCAGGGCCTCTACAACGGTTCTGCCCCAGTCGATCTGGGCATGATCCCGACATCC
GCCATCAGCAGAATTGAAGTCCTTCGGGAAGGGGCGGCGGCGCAGTACGGTTCGGACGCGATCTCCGGTGTCATCAACGT
CCTGCTCAAGGACACCGAGGGCGGCTCACTCAGCGCTCAGTACGGCCAGAACATGGACCGTAGCGACGGCGAGCAACTGC
TCATCCGGGGTGATTACGGCTTCGGCATATCAGACGCCGGCTCCCTGAACCTGTTCTTTTCCGTCACCCGGCAGAACCGA
TCCGACCGCTCATTCCCCGTCGCCTCCACCGTTCAGCTTTATCCGAGGCTGGCGAATGGCCAGCCCGATCCGCGGGAGGC
CACGGTCAATCGCCTCATCAGTCGCGGCTTTGGCATCTTCCCGGCCAAGCAGTGGCAGATCGGGTTCAACGGAAAACAAC
AGATCGGAGAGCTCGAGGCGTACGCCTTTGGTACGTACGGCCGCCGCATCACGGACATCATCTACCCGCCGATCATTCCC
AACCAGTCGGTCGCACTTCCGGAGATCTACCCGAACTTCGCCTATCCGGTTCAGCGGATCCGGGAAACGGACGGCGCGCT
CGCCATCGGTCTCCGCGGGGACCTCAACGACTGGAACTGGAACCTTTCGTCCAGCCTCGGCGAGAACCGCGCCCCGCAGG
ATATGCTGGAAAGCCTGAATGCGAGCCTCGGGCCGACGACCCAGACCGACTTCTACATCGGCGCCCTCTCCGCGCGCGAG
TGGGTAAACTCGCTGGACGTCACGCGTCGTTTCGATCTTGCCGGGGGCGGCGCGCTGCAGGTGTCGTTCGGGGCTCAGCA
CCGACTGGAGCGTTTCAAGATCTCCCCCGGCGAGCCGGCGAGCTACGTCCTGGGGACCTACGTGAGGCCCGCCGGCCAGG
CGTTCGCGGGCGTGCCGCTGCCGGGCGGAGCGTTCTTCGCTCCGGGCCTGCGGCCCGCCGACTCCGGCTCGTGGAGCCGG
AACGTCGTCGCCGGCTATGTCGAGCTTGGTTATGAGCCGACGGATCGTCTGTTCGTGGGGACGGCGGGGCGGATCGAAAA
CTACGACGACTCGTCGGGCACGAGCCTCGTGGGAAAGATCGATGGTCGATACAAGCTCAATGAATGGCTGTCGCTGCGGG
GCTCCTTCGGCAACGGCTTCCGTGCGCCGAGCCTGGCGCAGCAGCACTATTCCAAGGCGAGCGTGACCCCGAGCACCGCC
GCAGCGAACCTGGGCACGGTCATCACCAACCAGATTCTGCCGGTTGGACACCCGGCGGCGGTCGCGCTTGGTTCATCGCC
GTTGAAGCCGGAGAAGTCGGTTGACGCGAGCGTGGGCCTCACGATCAGCCCAGCTCCCAACTTCAACGTCACCATCGACG
GGTACACCGTCAAACTCGACGACCGGATTGTCCTTGGGAGCATCCTGCAAGGCGCTGCAGTCGCCAATATTCTTGCGGCG
AACGGTATCGATCGAAACCTGACGGGACAGTATTTCACCAATGCGGTGAGCACACGGACGTCGGGCGTCGACATCATCGC
CACATATCGCAAGGATCTTGAGAACTTCGGCAATCTGAAGCTGACGGCGGCCGTCAACATCAACAAGACGAAGATCACTC
ACATCGATCCCAATCCAGCGGCGCTCAGCGCGCTGGGCGCCGCATACGTCCAGGTGGATCGCGTGGCTCGCGGTTACCTG
ACCGAAGCTGTTCCGGAGAGCAAAGTCGCCCTGGGGGTCAATTGGACCCGGGACAAGTTCGAGCTCAATCTCCAGGGTGT
TCGCTACGATGAGTTCACAGCGCCCGGCTCAACCGCCGCGCTGGATCGCTTCTTCCCGTCCCAGTGGATCGCGAACGCTC
AGGTCAGGTACAGCCTCACCGATCAGGTGACCGTGGCCGCCGGCGCGGACAACATTTTCAATGAGTATCCGCCAGCGAAC
AACATTCCGCTCGCGCAGTACGGCTACAACCAATATCCGCGCTTCGGTCCGTTCGGGTTTACCGGCGGCTTCTACTATGG
CCGTGTCGAGGTGAAGTTCTAG

Upstream 100 bases:

>100_bases
AGCGTTATCGGTCTTTGAGTGCATCGATTGGCTTCAGCATAGTGCACGTCCATGGCGCATGCCCAATGCGGCCAAACGAC
AGCAATTCAAGGGGGTTGGT

Downstream 100 bases:

>100_bases
TTCGTTCTCATGGCCTCAGCGGGCGGATGATTGCAGTAGTCCGCGCATCCGTCCGCTGTGGACCTCAATGTCGCGCGCGT
TACGGCGCGCGTAGCTCCCA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 833; Mature: 832

Protein sequence:

>833_residues
MAQECNRGGRVRLFRNTSAAAIFAGAVFASSAHAQAADPSGQGGADTLTEVVVTGVRGQPRSKLDSPTPIDVLSGEEIAK
GGHANLYQDMQLQVPSFNYTTKAGSGTSSAILTGGLRGLNPDHTLVLVNGLRRHHTSLINVGQGLYNGSAPVDLGMIPTS
AISRIEVLREGAAAQYGSDAISGVINVLLKDTEGGSLSAQYGQNMDRSDGEQLLIRGDYGFGISDAGSLNLFFSVTRQNR
SDRSFPVASTVQLYPRLANGQPDPREATVNRLISRGFGIFPAKQWQIGFNGKQQIGELEAYAFGTYGRRITDIIYPPIIP
NQSVALPEIYPNFAYPVQRIRETDGALAIGLRGDLNDWNWNLSSSLGENRAPQDMLESLNASLGPTTQTDFYIGALSARE
WVNSLDVTRRFDLAGGGALQVSFGAQHRLERFKISPGEPASYVLGTYVRPAGQAFAGVPLPGGAFFAPGLRPADSGSWSR
NVVAGYVELGYEPTDRLFVGTAGRIENYDDSSGTSLVGKIDGRYKLNEWLSLRGSFGNGFRAPSLAQQHYSKASVTPSTA
AANLGTVITNQILPVGHPAAVALGSSPLKPEKSVDASVGLTISPAPNFNVTIDGYTVKLDDRIVLGSILQGAAVANILAA
NGIDRNLTGQYFTNAVSTRTSGVDIIATYRKDLENFGNLKLTAAVNINKTKITHIDPNPAALSALGAAYVQVDRVARGYL
TEAVPESKVALGVNWTRDKFELNLQGVRYDEFTAPGSTAALDRFFPSQWIANAQVRYSLTDQVTVAAGADNIFNEYPPAN
NIPLAQYGYNQYPRFGPFGFTGGFYYGRVEVKF

Sequences:

>Translated_833_residues
MAQECNRGGRVRLFRNTSAAAIFAGAVFASSAHAQAADPSGQGGADTLTEVVVTGVRGQPRSKLDSPTPIDVLSGEEIAK
GGHANLYQDMQLQVPSFNYTTKAGSGTSSAILTGGLRGLNPDHTLVLVNGLRRHHTSLINVGQGLYNGSAPVDLGMIPTS
AISRIEVLREGAAAQYGSDAISGVINVLLKDTEGGSLSAQYGQNMDRSDGEQLLIRGDYGFGISDAGSLNLFFSVTRQNR
SDRSFPVASTVQLYPRLANGQPDPREATVNRLISRGFGIFPAKQWQIGFNGKQQIGELEAYAFGTYGRRITDIIYPPIIP
NQSVALPEIYPNFAYPVQRIRETDGALAIGLRGDLNDWNWNLSSSLGENRAPQDMLESLNASLGPTTQTDFYIGALSARE
WVNSLDVTRRFDLAGGGALQVSFGAQHRLERFKISPGEPASYVLGTYVRPAGQAFAGVPLPGGAFFAPGLRPADSGSWSR
NVVAGYVELGYEPTDRLFVGTAGRIENYDDSSGTSLVGKIDGRYKLNEWLSLRGSFGNGFRAPSLAQQHYSKASVTPSTA
AANLGTVITNQILPVGHPAAVALGSSPLKPEKSVDASVGLTISPAPNFNVTIDGYTVKLDDRIVLGSILQGAAVANILAA
NGIDRNLTGQYFTNAVSTRTSGVDIIATYRKDLENFGNLKLTAAVNINKTKITHIDPNPAALSALGAAYVQVDRVARGYL
TEAVPESKVALGVNWTRDKFELNLQGVRYDEFTAPGSTAALDRFFPSQWIANAQVRYSLTDQVTVAAGADNIFNEYPPAN
NIPLAQYGYNQYPRFGPFGFTGGFYYGRVEVKF
>Mature_832_residues
AQECNRGGRVRLFRNTSAAAIFAGAVFASSAHAQAADPSGQGGADTLTEVVVTGVRGQPRSKLDSPTPIDVLSGEEIAKG
GHANLYQDMQLQVPSFNYTTKAGSGTSSAILTGGLRGLNPDHTLVLVNGLRRHHTSLINVGQGLYNGSAPVDLGMIPTSA
ISRIEVLREGAAAQYGSDAISGVINVLLKDTEGGSLSAQYGQNMDRSDGEQLLIRGDYGFGISDAGSLNLFFSVTRQNRS
DRSFPVASTVQLYPRLANGQPDPREATVNRLISRGFGIFPAKQWQIGFNGKQQIGELEAYAFGTYGRRITDIIYPPIIPN
QSVALPEIYPNFAYPVQRIRETDGALAIGLRGDLNDWNWNLSSSLGENRAPQDMLESLNASLGPTTQTDFYIGALSAREW
VNSLDVTRRFDLAGGGALQVSFGAQHRLERFKISPGEPASYVLGTYVRPAGQAFAGVPLPGGAFFAPGLRPADSGSWSRN
VVAGYVELGYEPTDRLFVGTAGRIENYDDSSGTSLVGKIDGRYKLNEWLSLRGSFGNGFRAPSLAQQHYSKASVTPSTAA
ANLGTVITNQILPVGHPAAVALGSSPLKPEKSVDASVGLTISPAPNFNVTIDGYTVKLDDRIVLGSILQGAAVANILAAN
GIDRNLTGQYFTNAVSTRTSGVDIIATYRKDLENFGNLKLTAAVNINKTKITHIDPNPAALSALGAAYVQVDRVARGYLT
EAVPESKVALGVNWTRDKFELNLQGVRYDEFTAPGSTAALDRFFPSQWIANAQVRYSLTDQVTVAAGADNIFNEYPPANN
IPLAQYGYNQYPRFGPFGFTGGFYYGRVEVKF

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=201, Percent_Identity=34.8258706467662, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1788478, Length=141, Percent_Identity=30.4964539007092, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010101
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 89109; Mature: 88978

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQECNRGGRVRLFRNTSAAAIFAGAVFASSAHAQAADPSGQGGADTLTEVVVTGVRGQP
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
RSKLDSPTPIDVLSGEEIAKGGHANLYQDMQLQVPSFNYTTKAGSGTSSAILTGGLRGLN
HHCCCCCCCEEEECCHHHHCCCCCCCEECEEEECCCCCCEECCCCCCCCCEEECCCCCCC
PDHTLVLVNGLRRHHTSLINVGQGLYNGSAPVDLGMIPTSAISRIEVLREGAAAQYGSDA
CCCEEEEEECHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCHHHCCHHH
ISGVINVLLKDTEGGSLSAQYGQNMDRSDGEQLLIRGDYGFGISDAGSLNLFFSVTRQNR
HHHHHHHHEECCCCCEEEHHHCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCC
SDRSFPVASTVQLYPRLANGQPDPREATVNRLISRGFGIFPAKQWQIGFNGKQQIGELEA
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCCE
YAFGTYGRRITDIIYPPIIPNQSVALPEIYPNFAYPVQRIRETDGALAIGLRGDLNDWNW
EEECCCCCEEHHHCCCCCCCCCCEECCHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
NLSSSLGENRAPQDMLESLNASLGPTTQTDFYIGALSAREWVNSLDVTRRFDLAGGGALQ
CCHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEECCCCCEEE
VSFGAQHRLERFKISPGEPASYVLGTYVRPAGQAFAGVPLPGGAFFAPGLRPADSGSWSR
EECCCHHHHHHEECCCCCCHHHHHHHHCCCCCCCEECCCCCCCCEECCCCCCCCCCCCCC
NVVAGYVELGYEPTDRLFVGTAGRIENYDDSSGTSLVGKIDGRYKLNEWLSLRGSFGNGF
CEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCEEECHHHEECCCCCCCC
RAPSLAQQHYSKASVTPSTAAANLGTVITNQILPVGHPAAVALGSSPLKPEKSVDASVGL
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCE
TISPAPNFNVTIDGYTVKLDDRIVLGSILQGAAVANILAANGIDRNLTGQYFTNAVSTRT
EECCCCCCEEEECCEEEEECCEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
SGVDIIATYRKDLENFGNLKLTAAVNINKTKITHIDPNPAALSALGAAYVQVDRVARGYL
CCEEEEEHHHHHHHHCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
TEAVPESKVALGVNWTRDKFELNLQGVRYDEFTAPGSTAALDRFFPSQWIANAQVRYSLT
HHCCCCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHHCCHHHHCCCEEEEEEC
DQVTVAAGADNIFNEYPPANNIPLAQYGYNQYPRFGPFGFTGGFYYGRVEVKF
CCEEEEECCCHHHHCCCCCCCCEEHHCCCCCCCCCCCCCCCCCEEEEEEEEEC
>Mature Secondary Structure 
AQECNRGGRVRLFRNTSAAAIFAGAVFASSAHAQAADPSGQGGADTLTEVVVTGVRGQP
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
RSKLDSPTPIDVLSGEEIAKGGHANLYQDMQLQVPSFNYTTKAGSGTSSAILTGGLRGLN
HHCCCCCCCEEEECCHHHHCCCCCCCEECEEEECCCCCCEECCCCCCCCCEEECCCCCCC
PDHTLVLVNGLRRHHTSLINVGQGLYNGSAPVDLGMIPTSAISRIEVLREGAAAQYGSDA
CCCEEEEEECHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCHHHCCHHH
ISGVINVLLKDTEGGSLSAQYGQNMDRSDGEQLLIRGDYGFGISDAGSLNLFFSVTRQNR
HHHHHHHHEECCCCCEEEHHHCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCC
SDRSFPVASTVQLYPRLANGQPDPREATVNRLISRGFGIFPAKQWQIGFNGKQQIGELEA
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCCE
YAFGTYGRRITDIIYPPIIPNQSVALPEIYPNFAYPVQRIRETDGALAIGLRGDLNDWNW
EEECCCCCEEHHHCCCCCCCCCCEECCHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
NLSSSLGENRAPQDMLESLNASLGPTTQTDFYIGALSAREWVNSLDVTRRFDLAGGGALQ
CCHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHCCEEEEECCCCCEEE
VSFGAQHRLERFKISPGEPASYVLGTYVRPAGQAFAGVPLPGGAFFAPGLRPADSGSWSR
EECCCHHHHHHEECCCCCCHHHHHHHHCCCCCCCEECCCCCCCCEECCCCCCCCCCCCCC
NVVAGYVELGYEPTDRLFVGTAGRIENYDDSSGTSLVGKIDGRYKLNEWLSLRGSFGNGF
CEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCEEECHHHEECCCCCCCC
RAPSLAQQHYSKASVTPSTAAANLGTVITNQILPVGHPAAVALGSSPLKPEKSVDASVGL
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCCCE
TISPAPNFNVTIDGYTVKLDDRIVLGSILQGAAVANILAANGIDRNLTGQYFTNAVSTRT
EECCCCCCEEEECCEEEEECCEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCC
SGVDIIATYRKDLENFGNLKLTAAVNINKTKITHIDPNPAALSALGAAYVQVDRVARGYL
CCEEEEEHHHHHHHHCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
TEAVPESKVALGVNWTRDKFELNLQGVRYDEFTAPGSTAALDRFFPSQWIANAQVRYSLT
HHCCCCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCHHHHHHHCCHHHHCCCEEEEEEC
DQVTVAAGADNIFNEYPPANNIPLAQYGYNQYPRFGPFGFTGGFYYGRVEVKF
CCEEEEECCCHHHHCCCCCCCCEEHHCCCCCCCCCCCCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA