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The map label for this gene is virB9 [H]

Identifier: 197105816

GI number: 197105816

Start: 2666159

End: 2667007

Strand: Direct

Name: virB9 [H]

Synonym: PHZ_c2354

Alternate gene names: 197105816

Gene position: 2666159-2667007 (Clockwise)

Preceding gene: 197105815

Following gene: 197105817

Centisome position: 66.72

GC content: 67.37

Gene sequence:

>849_bases
ATGACGCTAAGGAACCTCATCCTTGTGGCCAGCCTGCTCGGCGCAGCGCCGGCCGTCGCCGCATCACCCCCGAAGACCCC
GGCCAGCGACCCGCGCATCCGAACCGTCGACTACGATCCGCAGCAGGTGATGCGGATCGTGGGCGTTCACAGGACCGCCA
CCCAGGTGCTGTTCGGTTCGGACGAGACGATCCAGCACGTGGCGCTCGGCGACACCTCAAGTTGGGAGGTCGCGGCTGAG
GGATCGATCCTGTTCATCAAGCCGACCTCGTTGCGCGCGCCCACCAATCTGCTCGTGACCACGGCGACCAGCACAGGGGA
GACACGCAACTATGTCTTCGAGCTGTCGGCTCGCTCCGGCAGCAGCGCCCGCACGGCGCCAGGCACGACCTTCGTGCTGC
GCGTTCGCCATCCACAGCAGGACCAGGCTCGTCTGGTCGGCGCGCTTGCCGCGGAGACCCGAGCTCTTGAGCAGCGTCTG
CTCACCCTGAAGCTCGAGCGCGGCGCGATCGAGGGAACGCGGAATCTCTCCTATGCGCTGCAGGGATCCCGGGCGATCGC
CCCGTCCGAAGTTTCTGACAATGGACGTTTCACTGTCCTCAGGTTCCCGGGCGCCCAGGCCATTCCAGGCCTCTTCGTCG
TGACGCCCGACGGATCGGAAGCGCTCGCGCCCTTCGACGTCCGCGGCGAGTTCGTCGTCGTCCACCAGACCGCGCCGCAA
CTGCGACTTCGCCGCGGCCGCGAGGTGCTCTGCATCCATAATCTCGCCTGGAGCCCCCGTGGCCCGCGCCTGACCACCGG
CACGGCCGCCCCTCAGGTCGATCGGATCCTGAAGGAACAACGCCGATGA

Upstream 100 bases:

>100_bases
CCTTCGGCTACGCCCGGGCGCCGATGTCGGAGTCCGACAGGTTGCGCAATCCGCTGGGCTTCCAGGTTTCGAGCTACCGC
GCGGACCCGGAGGTCATCCA

Downstream 100 bases:

>100_bases
TCGACCGTCCCTACGCACAGGCGCCAGGGGCGGAGCCGCCCCTGAACCGCGGCATCTCCCCCATTGCGGGAGCCCAGCGC
CGCCGGGTTGGCGCGGTCGT

Product: type IV secretory pathway, VirB9 component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTLRNLILVASLLGAAPAVAASPPKTPASDPRIRTVDYDPQQVMRIVGVHRTATQVLFGSDETIQHVALGDTSSWEVAAE
GSILFIKPTSLRAPTNLLVTTATSTGETRNYVFELSARSGSSARTAPGTTFVLRVRHPQQDQARLVGALAAETRALEQRL
LTLKLERGAIEGTRNLSYALQGSRAIAPSEVSDNGRFTVLRFPGAQAIPGLFVVTPDGSEALAPFDVRGEFVVVHQTAPQ
LRLRRGREVLCIHNLAWSPRGPRLTTGTAAPQVDRILKEQRR

Sequences:

>Translated_282_residues
MTLRNLILVASLLGAAPAVAASPPKTPASDPRIRTVDYDPQQVMRIVGVHRTATQVLFGSDETIQHVALGDTSSWEVAAE
GSILFIKPTSLRAPTNLLVTTATSTGETRNYVFELSARSGSSARTAPGTTFVLRVRHPQQDQARLVGALAAETRALEQRL
LTLKLERGAIEGTRNLSYALQGSRAIAPSEVSDNGRFTVLRFPGAQAIPGLFVVTPDGSEALAPFDVRGEFVVVHQTAPQ
LRLRRGREVLCIHNLAWSPRGPRLTTGTAAPQVDRILKEQRR
>Mature_281_residues
TLRNLILVASLLGAAPAVAASPPKTPASDPRIRTVDYDPQQVMRIVGVHRTATQVLFGSDETIQHVALGDTSSWEVAAEG
SILFIKPTSLRAPTNLLVTTATSTGETRNYVFELSARSGSSARTAPGTTFVLRVRHPQQDQARLVGALAAETRALEQRLL
TLKLERGAIEGTRNLSYALQGSRAIAPSEVSDNGRFTVLRFPGAQAIPGLFVVTPDGSEALAPFDVRGEFVVVHQTAPQL
RLRRGREVLCIHNLAWSPRGPRLTTGTAAPQVDRILKEQRR

Specific function: Component of the type IV secretion system virB/virD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function [H]

COG id: COG3504

COG function: function code U; Type IV secretory pathway, VirB9 components

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trbG/virB9 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010258
- InterPro:   IPR014148 [H]

Pfam domain/function: PF03524 CagX [H]

EC number: NA

Molecular weight: Translated: 30482; Mature: 30351

Theoretical pI: Translated: 11.20; Mature: 11.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRNLILVASLLGAAPAVAASPPKTPASDPRIRTVDYDPQQVMRIVGVHRTATQVLFGS
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCHHHEEEEECC
DETIQHVALGDTSSWEVAAEGSILFIKPTSLRAPTNLLVTTATSTGETRNYVFELSARSG
CCCEEEEEECCCCCCEEEECCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCC
SSARTAPGTTFVLRVRHPQQDQARLVGALAAETRALEQRLLTLKLERGAIEGTRNLSYAL
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEE
QGSRAIAPSEVSDNGRFTVLRFPGAQAIPGLFVVTPDGSEALAPFDVRGEFVVVHQTAPQ
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCEECCCCEEEEECCCCH
LRLRRGREVLCIHNLAWSPRGPRLTTGTAAPQVDRILKEQRR
HHHHCCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TLRNLILVASLLGAAPAVAASPPKTPASDPRIRTVDYDPQQVMRIVGVHRTATQVLFGS
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCHHHEEEEECC
DETIQHVALGDTSSWEVAAEGSILFIKPTSLRAPTNLLVTTATSTGETRNYVFELSARSG
CCCEEEEEECCCCCCEEEECCCEEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCC
SSARTAPGTTFVLRVRHPQQDQARLVGALAAETRALEQRLLTLKLERGAIEGTRNLSYAL
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEE
QGSRAIAPSEVSDNGRFTVLRFPGAQAIPGLFVVTPDGSEALAPFDVRGEFVVVHQTAPQ
CCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCEECCCCEEEEECCCCH
LRLRRGREVLCIHNLAWSPRGPRLTTGTAAPQVDRILKEQRR
HHHHCCCEEEEEECCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA