Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 197105788

GI number: 197105788

Start: 2638572

End: 2639681

Strand: Reverse

Name: mraY

Synonym: PHZ_c2326

Alternate gene names: 197105788

Gene position: 2639681-2638572 (Counterclockwise)

Preceding gene: 197105789

Following gene: 197105787

Centisome position: 66.05

GC content: 66.85

Gene sequence:

>1110_bases
ATGTTCTACTGGCTGTACGAACAGTTCGCGGCGTCGGGCTATGTCCCGATCCTCAACCTGCTGAAATACCAGACCTTCCG
GACCGGCCTTGCGATCTTCACGGCCCAGTTCGTGGTCGTGGCCATGGGCTCGCGCTTCATCCGCTGGATGCAGGCCAAGC
AGGGCAAGGGCCAGCCGATCCGCGCCGAGGGCATCGAGCGCCACGTGATCGAGAAGGCCGGCACGCCGACCATGGGCGGG
GTGATGATCCTGGCCGGCCTGCTGGTGGGCACGCTGCTGTGGAGCGACCTGTCGAACCCCTACGTCTGGGCGGTCGTGCT
GGTCACCGCCGGCTACGGCCTGCTGGGCTTCACCGACGACTACGCCAAGGTCACCCGCCAGACGACGGCGGGGGTCTCGG
GCAAGATCCGGCTGGCGCTCGAGGCGTTCATCGCCATGGCGGCGGTGCTGATCATCATCGTCTTCGCCCAGAAGCCGCCC
GAGAACCCCGAGCTGCTGACCTCGGTGACCTTCCCGATCTTCAAGCAGTACTTCGTCGACCTCTCGTGGGGCTATCTGCT
GTTCGGCGCCTTCATCATCGTGGGCGCGGCGAACGCCGTGAACTTCACCGACGGCCTCGACGGCCTGGCCACGGTGCCGG
TGATGATCGCCGCGGCGGCCTACGGCCTGATCGCCTACCTGGTCGGCAACTACGTCTTCTCGAACTACCTGCAGCTCCAC
TTCGTGCCGGGCGTGGGCGAGATCGCGGTCTTCTGCGGCGCCCTGATCGGCTCGGGGCTGGGCTTCCTCTGGTACAACGC
CCCGCCGGCCAAGATCTTCATGGGCGACACCGGCTCGCTGGCCCTGGGCGGGGCGGTGGGCGCGGTGGCCGTCGCCACCC
GGCACGAGATCGTGCTGGCGATCATCGGCGGCCTGTTCGTTGCCGAGACGCTGTCGGTGATCATCCAGGTCGCCTGGTTC
AAGCGCACCGGCCGGCGGATCTTCCTGATGGCCCCGATCCACCACCACTTCGAGAAGCTGGGCTGGTCGGAATCGACCGT
CGTCATCCGCTTCTGGATCGTCGCCATCATGCTGGCCCTCGTGGGCCTCGCCACCCTGAAGCTCAGGTAG

Upstream 100 bases:

>100_bases
CCGGCGACGTGGTGATGGTGAAGGGGTCGAACGGATCGAAGGCGGGCGCGATCGCGGCCGCCCTGTCCGCGCTCGATTCC
CGGTCGGGGGAGGGCGCCTG

Downstream 100 bases:

>100_bases
GGGAGGGCGCGCGGTCAGATGATCCCGGTCAGCGGCTTCGAGGGACGGACGGTCGCCGTGTTCGGCCTGGCCCGCACGGG
CCTGGCCGCCGCGCGCGCGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MFYWLYEQFAASGYVPILNLLKYQTFRTGLAIFTAQFVVVAMGSRFIRWMQAKQGKGQPIRAEGIERHVIEKAGTPTMGG
VMILAGLLVGTLLWSDLSNPYVWAVVLVTAGYGLLGFTDDYAKVTRQTTAGVSGKIRLALEAFIAMAAVLIIIVFAQKPP
ENPELLTSVTFPIFKQYFVDLSWGYLLFGAFIIVGAANAVNFTDGLDGLATVPVMIAAAAYGLIAYLVGNYVFSNYLQLH
FVPGVGEIAVFCGALIGSGLGFLWYNAPPAKIFMGDTGSLALGGAVGAVAVATRHEIVLAIIGGLFVAETLSVIIQVAWF
KRTGRRIFLMAPIHHHFEKLGWSESTVVIRFWIVAIMLALVGLATLKLR

Sequences:

>Translated_369_residues
MFYWLYEQFAASGYVPILNLLKYQTFRTGLAIFTAQFVVVAMGSRFIRWMQAKQGKGQPIRAEGIERHVIEKAGTPTMGG
VMILAGLLVGTLLWSDLSNPYVWAVVLVTAGYGLLGFTDDYAKVTRQTTAGVSGKIRLALEAFIAMAAVLIIIVFAQKPP
ENPELLTSVTFPIFKQYFVDLSWGYLLFGAFIIVGAANAVNFTDGLDGLATVPVMIAAAAYGLIAYLVGNYVFSNYLQLH
FVPGVGEIAVFCGALIGSGLGFLWYNAPPAKIFMGDTGSLALGGAVGAVAVATRHEIVLAIIGGLFVAETLSVIIQVAWF
KRTGRRIFLMAPIHHHFEKLGWSESTVVIRFWIVAIMLALVGLATLKLR
>Mature_369_residues
MFYWLYEQFAASGYVPILNLLKYQTFRTGLAIFTAQFVVVAMGSRFIRWMQAKQGKGQPIRAEGIERHVIEKAGTPTMGG
VMILAGLLVGTLLWSDLSNPYVWAVVLVTAGYGLLGFTDDYAKVTRQTTAGVSGKIRLALEAFIAMAAVLIIIVFAQKPP
ENPELLTSVTFPIFKQYFVDLSWGYLLFGAFIIVGAANAVNFTDGLDGLATVPVMIAAAAYGLIAYLVGNYVFSNYLQLH
FVPGVGEIAVFCGALIGSGLGFLWYNAPPAKIFMGDTGSLALGGAVGAVAVATRHEIVLAIIGGLFVAETLSVIIQVAWF
KRTGRRIFLMAPIHHHFEKLGWSESTVVIRFWIVAIMLALVGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=369, Percent_Identity=46.6124661246612, Blast_Score=318, Evalue=3e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PHEZH (B4RFS3)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002131165.1
- GeneID:   6791847
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c2326
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 40012; Mature: 40012

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2111d4c4)-; HASH(0x2250d934)-; HASH(0x22b7c2c4)-; HASH(0x22b40b60)-; HASH(0x22b6f9a4)-; HASH(0x22b820b0)-; HASH(0x220af3b4)-; HASH(0x22ad8eec)-; HASH(0x22b76fd0)-; HASH(0x220299ec)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYWLYEQFAASGYVPILNLLKYQTFRTGLAIFTAQFVVVAMGSRFIRWMQAKQGKGQPI
CEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RAEGIERHVIEKAGTPTMGGVMILAGLLVGTLLWSDLSNPYVWAVVLVTAGYGLLGFTDD
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHH
YAKVTRQTTAGVSGKIRLALEAFIAMAAVLIIIVFAQKPPENPELLTSVTFPIFKQYFVD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LSWGYLLFGAFIIVGAANAVNFTDGLDGLATVPVMIAAAAYGLIAYLVGNYVFSNYLQLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
FVPGVGEIAVFCGALIGSGLGFLWYNAPPAKIFMGDTGSLALGGAVGAVAVATRHEIVLA
EECCCHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHH
IIGGLFVAETLSVIIQVAWFKRTGRRIFLMAPIHHHFEKLGWSESTVVIRFWIVAIMLAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VGLATLKLR
HHHHHHCCH
>Mature Secondary Structure
MFYWLYEQFAASGYVPILNLLKYQTFRTGLAIFTAQFVVVAMGSRFIRWMQAKQGKGQPI
CEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RAEGIERHVIEKAGTPTMGGVMILAGLLVGTLLWSDLSNPYVWAVVLVTAGYGLLGFTDD
CHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHH
YAKVTRQTTAGVSGKIRLALEAFIAMAAVLIIIVFAQKPPENPELLTSVTFPIFKQYFVD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LSWGYLLFGAFIIVGAANAVNFTDGLDGLATVPVMIAAAAYGLIAYLVGNYVFSNYLQLH
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
FVPGVGEIAVFCGALIGSGLGFLWYNAPPAKIFMGDTGSLALGGAVGAVAVATRHEIVLA
EECCCHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCEEECCHHHHHHHHHHHHHHHH
IIGGLFVAETLSVIIQVAWFKRTGRRIFLMAPIHHHFEKLGWSESTVVIRFWIVAIMLAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VGLATLKLR
HHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA