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The map label for this gene is yjjL [H]

Identifier: 197105597

GI number: 197105597

Start: 2401111

End: 2402460

Strand: Reverse

Name: yjjL [H]

Synonym: PHZ_c2134

Alternate gene names: 197105597

Gene position: 2402460-2401111 (Counterclockwise)

Preceding gene: 197105601

Following gene: 197105596

Centisome position: 60.12

GC content: 71.33

Gene sequence:

>1350_bases
ATGCGGGATATGCCGTCGGGGGCCGTCGAGGGGCAGCCGTATCCGTCGCCAGCCTACGCCTATTACAGCGTGGGCGTCCT
GATGCTCGCCTACATCTTCGCGTTCGTGGACCGGATCGCGCTCGGCCTGGTGGTCGATCCCATCCGCCGCGACCTGGGCC
TGACCGACACGCAGGTCAGCGCGCTGGCGGGCCTCGCGTTCGTGGTCTGCTTCGTGATCTTCTCGTTCCCGTTCGGCCGC
TGGGTGGACCGCCGCGCGCGGCCGCCAGCCCTCACGCTCGGGATCAGCGTCTGGAGCCTGGCCATGGCGGGCTGCGGCCT
GGCCACCAACTTCTGGCAGCTGTTCGTCGGGCGCATGCTGGTCGGCGTTGGCGAGGCGGCGGTCAATCCGGTCGCCTATT
CGACGATCCCCGACAGCTTCCCGCCGCACCGCCGGGGCTTCGCGATGGGGATCTACGCCTCGGGCGCGTCGATCGGCGGC
GGGTTCGCCGTCTATCTCGGTAGCCTCATCCTGGCCTGGGCCGAGATCGCCCAGCCGTCCCTGCCGATCGTGGGGCCGCT
GGCGCCGTGGCAGGCGCTGTTCATCGGCCTTGGCCTGCCGGGTCTGCTGGTGGCCCTCCTGGTGCGCTTCACCCTGCGCG
ACCCGCCGCGGCGCGGGCAGAGCGCGGCGCCGGTCGCCTCCCGCGACGTGACCGCCTACTTCCTGGAGCACCGGACGCTG
TTCATCCTGATGTTCCTGGGTTTTTCCGGCTTCGCCATTAGCAACTACGCCTTCACCGTCTGGGGCCCCACCTACTTCAT
GCGGGTGCACGAGATGAGCGTGGCGCGGGTCGGGCTGCTGATGGGCCTCGGCTACGCCATCTTCGGCACGATCGGCGTGC
TGCTGGGCGGCGCCTGGGCCGATCGCGTACGCAAGGCCGGCGACCCGGTGGCTCCCATCTGGGTGGCCCTGTGGATCGCG
GGGCTGCAGGCGCCGTTCTTCCTGGGCGCCTACCTGTCTCCCGACGCCACCGTCGCCCTGGTCCTGTTCTGCGCCGGCAT
GCTGACCGCCTGCATGATCGGCGGCCTGCAGGGGGCGATGGTGCAGGTGCTCACGCCCAACCGGATGCGGGGCCAGGCCG
GGGCGGTCTACCTCACCGTGGTCAACGTCCTGGGCCTGGGCGTGGCGCCCACCGCCACGGCGGCCATGACCGACTATGTG
TTCGGCGGGCCCGAGCACATCGGCAAGTCGCTGGCGGCCACCACCGCCGGCGCCCTGGGCCTGGCCGCGCTGCTGCTGGT
CATCGGCATGCGCCTGGCCCGCGCCCGGGCCCGCGCCGTGGCGGACGAAGAGGCCAAGACGCTCTTCTAG

Upstream 100 bases:

>100_bases
ATGGGCGAGTGGCGGAAAAATATCTGTTGGCTCATCCAGCTTGTATGCAATGACAGGTGGCGAGCCGTCGCCAAAGGCGG
CCAGGATCGAGGGGGAGCGC

Downstream 100 bases:

>100_bases
TGAATGCAATCATCTTCCCGACCTAGAGGATGCGGGCGGGATCATCGCTGTAGACAAGCAGATTGCATCCATTACGGTCA
GCTGATCTGAGTTCCACAGC

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRDMPSGAVEGQPYPSPAYAYYSVGVLMLAYIFAFVDRIALGLVVDPIRRDLGLTDTQVSALAGLAFVVCFVIFSFPFGR
WVDRRARPPALTLGISVWSLAMAGCGLATNFWQLFVGRMLVGVGEAAVNPVAYSTIPDSFPPHRRGFAMGIYASGASIGG
GFAVYLGSLILAWAEIAQPSLPIVGPLAPWQALFIGLGLPGLLVALLVRFTLRDPPRRGQSAAPVASRDVTAYFLEHRTL
FILMFLGFSGFAISNYAFTVWGPTYFMRVHEMSVARVGLLMGLGYAIFGTIGVLLGGAWADRVRKAGDPVAPIWVALWIA
GLQAPFFLGAYLSPDATVALVLFCAGMLTACMIGGLQGAMVQVLTPNRMRGQAGAVYLTVVNVLGLGVAPTATAAMTDYV
FGGPEHIGKSLAATTAGALGLAALLLVIGMRLARARARAVADEEAKTLF

Sequences:

>Translated_449_residues
MRDMPSGAVEGQPYPSPAYAYYSVGVLMLAYIFAFVDRIALGLVVDPIRRDLGLTDTQVSALAGLAFVVCFVIFSFPFGR
WVDRRARPPALTLGISVWSLAMAGCGLATNFWQLFVGRMLVGVGEAAVNPVAYSTIPDSFPPHRRGFAMGIYASGASIGG
GFAVYLGSLILAWAEIAQPSLPIVGPLAPWQALFIGLGLPGLLVALLVRFTLRDPPRRGQSAAPVASRDVTAYFLEHRTL
FILMFLGFSGFAISNYAFTVWGPTYFMRVHEMSVARVGLLMGLGYAIFGTIGVLLGGAWADRVRKAGDPVAPIWVALWIA
GLQAPFFLGAYLSPDATVALVLFCAGMLTACMIGGLQGAMVQVLTPNRMRGQAGAVYLTVVNVLGLGVAPTATAAMTDYV
FGGPEHIGKSLAATTAGALGLAALLLVIGMRLARARARAVADEEAKTLF
>Mature_449_residues
MRDMPSGAVEGQPYPSPAYAYYSVGVLMLAYIFAFVDRIALGLVVDPIRRDLGLTDTQVSALAGLAFVVCFVIFSFPFGR
WVDRRARPPALTLGISVWSLAMAGCGLATNFWQLFVGRMLVGVGEAAVNPVAYSTIPDSFPPHRRGFAMGIYASGASIGG
GFAVYLGSLILAWAEIAQPSLPIVGPLAPWQALFIGLGLPGLLVALLVRFTLRDPPRRGQSAAPVASRDVTAYFLEHRTL
FILMFLGFSGFAISNYAFTVWGPTYFMRVHEMSVARVGLLMGLGYAIFGTIGVLLGGAWADRVRKAGDPVAPIWVALWIA
GLQAPFFLGAYLSPDATVALVLFCAGMLTACMIGGLQGAMVQVLTPNRMRGQAGAVYLTVVNVLGLGVAPTATAAMTDYV
FGGPEHIGKSLAATTAGALGLAALLLVIGMRLARARARAVADEEAKTLF

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI215490096, Length=407, Percent_Identity=25.0614250614251, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI14042968, Length=407, Percent_Identity=25.0614250614251, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI194239645, Length=408, Percent_Identity=23.5294117647059, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI215490100, Length=388, Percent_Identity=24.2268041237113, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI2367379, Length=392, Percent_Identity=26.530612244898, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082320, Length=388, Percent_Identity=22.680412371134, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082231, Length=230, Percent_Identity=26.5217391304348, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87082404, Length=219, Percent_Identity=26.4840182648402, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17539092, Length=466, Percent_Identity=24.8927038626609, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17557872, Length=320, Percent_Identity=23.125, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654037, Length=449, Percent_Identity=22.71714922049, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24654041, Length=449, Percent_Identity=22.71714922049, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24654039, Length=452, Percent_Identity=22.5663716814159, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640209, Length=163, Percent_Identity=30.0613496932515, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17864456, Length=452, Percent_Identity=22.5663716814159, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47492; Mature: 47492

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDMPSGAVEGQPYPSPAYAYYSVGVLMLAYIFAFVDRIALGLVVDPIRRDLGLTDTQVS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALAGLAFVVCFVIFSFPFGRWVDRRARPPALTLGISVWSLAMAGCGLATNFWQLFVGRML
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHH
VGVGEAAVNPVAYSTIPDSFPPHRRGFAMGIYASGASIGGGFAVYLGSLILAWAEIAQPS
HHCCHHHCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
LPIVGPLAPWQALFIGLGLPGLLVALLVRFTLRDPPRRGQSAAPVASRDVTAYFLEHRTL
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FILMFLGFSGFAISNYAFTVWGPTYFMRVHEMSVARVGLLMGLGYAIFGTIGVLLGGAWA
HHHHHHCCCCCEECCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DRVRKAGDPVAPIWVALWIAGLQAPFFLGAYLSPDATVALVLFCAGMLTACMIGGLQGAM
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
VQVLTPNRMRGQAGAVYLTVVNVLGLGVAPTATAAMTDYVFGGPEHIGKSLAATTAGALG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LAALLLVIGMRLARARARAVADEEAKTLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRDMPSGAVEGQPYPSPAYAYYSVGVLMLAYIFAFVDRIALGLVVDPIRRDLGLTDTQVS
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ALAGLAFVVCFVIFSFPFGRWVDRRARPPALTLGISVWSLAMAGCGLATNFWQLFVGRML
HHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHH
VGVGEAAVNPVAYSTIPDSFPPHRRGFAMGIYASGASIGGGFAVYLGSLILAWAEIAQPS
HHCCHHHCCCCEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
LPIVGPLAPWQALFIGLGLPGLLVALLVRFTLRDPPRRGQSAAPVASRDVTAYFLEHRTL
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
FILMFLGFSGFAISNYAFTVWGPTYFMRVHEMSVARVGLLMGLGYAIFGTIGVLLGGAWA
HHHHHHCCCCCEECCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DRVRKAGDPVAPIWVALWIAGLQAPFFLGAYLSPDATVALVLFCAGMLTACMIGGLQGAM
HHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCE
VQVLTPNRMRGQAGAVYLTVVNVLGLGVAPTATAAMTDYVFGGPEHIGKSLAATTAGALG
EEEECCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LAALLLVIGMRLARARARAVADEEAKTLF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]