Click here to switch to the map view.

The map label for this gene is yjjL [H]

Identifier: 197105596

GI number: 197105596

Start: 2399648

End: 2400997

Strand: Reverse

Name: yjjL [H]

Synonym: PHZ_c2133

Alternate gene names: 197105596

Gene position: 2400997-2399648 (Counterclockwise)

Preceding gene: 197105597

Following gene: 197105593

Centisome position: 60.08

GC content: 74.3

Gene sequence:

>1350_bases
ATGACGCTTGCGAAGACGCAGGATCGGCCGGCCTCGCCGCCGGCGGGCGCCTACCGCGCCTACCTGATGGTGCTGCTGAC
CAGCGCCTATGCCCTGAACCTGCTCGACCGGCAGATCCTCAACGTCCTCGCCGAGCCCATCAAGCGCGACCTGCACCTGG
CGGATTGGCAGCTTGGGGCGCTGACCGGCCTGTCGTTCGCCCTGCTGCACAGCCTGGCGGCGGTGCCCATCGCGCGGCTC
GCCGACCGCGGGGACCGGGTGCGCATCGTCGGCCTGGCGATCCTCGCCTGGAGCGCCTTCACGGCGATGAGCGGGGCGGC
CGCCAATTTCGTCCAGCTGCTGCTGCTGCGGATCGGCGTCGGGGTCGGTGAGGCGGGATGCCAGCCGCCCGCCCAGTCCC
TGATCGTCGACCACTATCCGCCCGAGCGGCGGGCGGGCGCGCTCGGCAAGTTCGGGCTGGGCAAGCCGGTGGGCGCGGCC
GTCGGCCTGGCCGCGGGCGGCCTCCTGGCCGAGGCGGTGGGCTGGCGCTGGACGCTGGTGATCGCCGGGGCTCCTGGGCT
GGTGATCGGCCTCCTCGTGCTGCTGACGCTGAAGGACCCCCGCCGGGCCCCGGCCGCCGTCGCGCCGGCGGTCCAGCGGC
CGCTCGGCGCCGTGCTCCGCGAGCTCGCCGGCCGACGCGCCTTCGTGCTGATCATGGTCGGCGTGGGCCTGCTGGCCTTC
ATGAGCTACGGCGCCAACGCCTTCGCCGCCTCCTTCTACCTGCGGGTCCACGGCGAAGACGTCGCGCGGATCGGCCAGGC
GCTGGGCGTGGGGCCGCTGGCGGTGATCGGCCTGGGCATGGGCCTGATCGGGGCCAGCGCCGGCGCCCTCGGCAGCTGGT
TCGGCGGCCATGTCGGCGACCGCTGGGGCGCCCGTGATCCGCGGGCCTACGCCTGGATCCCGGCTGGCGGCGCGCTGCTC
GGCGCGCTGGCCTACATGGCGATGTTCACGGTCCCCAGCGGCGCGTGGTCCCTGGCGCTCTATGCGGCGCCGGCCTTCCT
GAACAACCTCTGGAACGGGCCGGCCTCGCTGGCCGTCCAGAACCTGGCCGGCGAGCGTGCGAGGGCGACGGCCATCGCCC
TGGTGCTGTTCGTGGGCAGCGCGCTGGGAATGGGGTTCGGCCCGCTCACGGTGGGCCTGATGAGCGACGCCTTCTCGGCG
TCCCTGGGCGAGGCCGAGGGCCTCCGCCGCGCCATCGTGCTGTGCGCGGCCGTCGATATCCTGGCCTGCGTCAGCTTCCT
CGTGGCGGGACGCTACCTGCGGCAGGATCTGGCGGATGCGGAGGCCGCGGAGGCCCAGGCGATCCGCTGA

Upstream 100 bases:

>100_bases
CTTCCCGACCTAGAGGATGCGGGCGGGATCATCGCTGTAGACAAGCAGATTGCATCCATTACGGTCAGCTGATCTGAGTT
CCACAGCCGGCGGGGCGATC

Downstream 100 bases:

>100_bases
CCGCGACGCCGGCCCCGCCGCGCCCGAACGGAGAGGGGCGGCGGGGGGCGTCTTCGCGCCGCCTACTTCAGGGCGGCGAG
GGCGGCTTCCGCCACTTCCT

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTLAKTQDRPASPPAGAYRAYLMVLLTSAYALNLLDRQILNVLAEPIKRDLHLADWQLGALTGLSFALLHSLAAVPIARL
ADRGDRVRIVGLAILAWSAFTAMSGAAANFVQLLLLRIGVGVGEAGCQPPAQSLIVDHYPPERRAGALGKFGLGKPVGAA
VGLAAGGLLAEAVGWRWTLVIAGAPGLVIGLLVLLTLKDPRRAPAAVAPAVQRPLGAVLRELAGRRAFVLIMVGVGLLAF
MSYGANAFAASFYLRVHGEDVARIGQALGVGPLAVIGLGMGLIGASAGALGSWFGGHVGDRWGARDPRAYAWIPAGGALL
GALAYMAMFTVPSGAWSLALYAAPAFLNNLWNGPASLAVQNLAGERARATAIALVLFVGSALGMGFGPLTVGLMSDAFSA
SLGEAEGLRRAIVLCAAVDILACVSFLVAGRYLRQDLADAEAAEAQAIR

Sequences:

>Translated_449_residues
MTLAKTQDRPASPPAGAYRAYLMVLLTSAYALNLLDRQILNVLAEPIKRDLHLADWQLGALTGLSFALLHSLAAVPIARL
ADRGDRVRIVGLAILAWSAFTAMSGAAANFVQLLLLRIGVGVGEAGCQPPAQSLIVDHYPPERRAGALGKFGLGKPVGAA
VGLAAGGLLAEAVGWRWTLVIAGAPGLVIGLLVLLTLKDPRRAPAAVAPAVQRPLGAVLRELAGRRAFVLIMVGVGLLAF
MSYGANAFAASFYLRVHGEDVARIGQALGVGPLAVIGLGMGLIGASAGALGSWFGGHVGDRWGARDPRAYAWIPAGGALL
GALAYMAMFTVPSGAWSLALYAAPAFLNNLWNGPASLAVQNLAGERARATAIALVLFVGSALGMGFGPLTVGLMSDAFSA
SLGEAEGLRRAIVLCAAVDILACVSFLVAGRYLRQDLADAEAAEAQAIR
>Mature_448_residues
TLAKTQDRPASPPAGAYRAYLMVLLTSAYALNLLDRQILNVLAEPIKRDLHLADWQLGALTGLSFALLHSLAAVPIARLA
DRGDRVRIVGLAILAWSAFTAMSGAAANFVQLLLLRIGVGVGEAGCQPPAQSLIVDHYPPERRAGALGKFGLGKPVGAAV
GLAAGGLLAEAVGWRWTLVIAGAPGLVIGLLVLLTLKDPRRAPAAVAPAVQRPLGAVLRELAGRRAFVLIMVGVGLLAFM
SYGANAFAASFYLRVHGEDVARIGQALGVGPLAVIGLGMGLIGASAGALGSWFGGHVGDRWGARDPRAYAWIPAGGALLG
ALAYMAMFTVPSGAWSLALYAAPAFLNNLWNGPASLAVQNLAGERARATAIALVLFVGSALGMGFGPLTVGLMSDAFSAS
LGEAEGLRRAIVLCAAVDILACVSFLVAGRYLRQDLADAEAAEAQAIR

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI185136021, Length=457, Percent_Identity=26.9146608315098, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI215490096, Length=452, Percent_Identity=28.0973451327434, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI14042968, Length=452, Percent_Identity=28.0973451327434, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI215490100, Length=437, Percent_Identity=27.9176201372998, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI2367379, Length=169, Percent_Identity=33.7278106508876, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082320, Length=197, Percent_Identity=26.9035532994924, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789152, Length=192, Percent_Identity=25, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788710, Length=196, Percent_Identity=27.5510204081633, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17557872, Length=462, Percent_Identity=23.3766233766234, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17539092, Length=434, Percent_Identity=23.5023041474654, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654037, Length=394, Percent_Identity=25.1269035532995, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24654041, Length=394, Percent_Identity=25.1269035532995, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17864456, Length=393, Percent_Identity=24.9363867684478, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654039, Length=393, Percent_Identity=24.9363867684478, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654044, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640209, Length=152, Percent_Identity=26.9736842105263, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46259; Mature: 46128

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLAKTQDRPASPPAGAYRAYLMVLLTSAYALNLLDRQILNVLAEPIKRDLHLADWQLGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LTGLSFALLHSLAAVPIARLADRGDRVRIVGLAILAWSAFTAMSGAAANFVQLLLLRIGV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GVGEAGCQPPAQSLIVDHYPPERRAGALGKFGLGKPVGAAVGLAAGGLLAEAVGWRWTLV
CCCCCCCCCCHHHHEECCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IAGAPGLVIGLLVLLTLKDPRRAPAAVAPAVQRPLGAVLRELAGRRAFVLIMVGVGLLAF
EECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MSYGANAFAASFYLRVHGEDVARIGQALGVGPLAVIGLGMGLIGASAGALGSWFGGHVGD
HHCCCHHHHHEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
RWGARDPRAYAWIPAGGALLGALAYMAMFTVPSGAWSLALYAAPAFLNNLWNGPASLAVQ
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
NLAGERARATAIALVLFVGSALGMGFGPLTVGLMSDAFSASLGEAEGLRRAIVLCAAVDI
HHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LACVSFLVAGRYLRQDLADAEAAEAQAIR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLAKTQDRPASPPAGAYRAYLMVLLTSAYALNLLDRQILNVLAEPIKRDLHLADWQLGA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LTGLSFALLHSLAAVPIARLADRGDRVRIVGLAILAWSAFTAMSGAAANFVQLLLLRIGV
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
GVGEAGCQPPAQSLIVDHYPPERRAGALGKFGLGKPVGAAVGLAAGGLLAEAVGWRWTLV
CCCCCCCCCCHHHHEECCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
IAGAPGLVIGLLVLLTLKDPRRAPAAVAPAVQRPLGAVLRELAGRRAFVLIMVGVGLLAF
EECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MSYGANAFAASFYLRVHGEDVARIGQALGVGPLAVIGLGMGLIGASAGALGSWFGGHVGD
HHCCCHHHHHEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCC
RWGARDPRAYAWIPAGGALLGALAYMAMFTVPSGAWSLALYAAPAFLNNLWNGPASLAVQ
CCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
NLAGERARATAIALVLFVGSALGMGFGPLTVGLMSDAFSASLGEAEGLRRAIVLCAAVDI
HHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LACVSFLVAGRYLRQDLADAEAAEAQAIR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]