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The map label for this gene is coaX

Identifier: 197105252

GI number: 197105252

Start: 2003076

End: 2003849

Strand: Reverse

Name: coaX

Synonym: PHZ_c1789

Alternate gene names: 197105252

Gene position: 2003849-2003076 (Counterclockwise)

Preceding gene: 197105253

Following gene: 197105251

Centisome position: 50.14

GC content: 68.48

Gene sequence:

>774_bases
ATGTTGCTGGCGATCGAACAGGGGAACACCAACACCCTCTTCGCGGTGCATGACGGCGAACGCTGGATCGCCCAGTGGCG
CGCGGCGACCGATTCCACCCGCACCGCCGACGAGTACGCGGTCTGGCTGTCGCAACTGCTGTCGATGGCCGGCCTGGCGC
TGGGCGCCTTCGACGGCTGCATCATCTCGAGCGTCGTGCCGCAGTCGATCTTCAACCTGCGCAACCTGTCCCGCCGCTAC
CTGCACGTCGAGCCGCTGGTGATCGGCGAGAACGCCGAACTCGGCATCCCCATCCGCATCGACAAGCCCTCGGAGGCGGG
AGCCGACCGCCTGGTGAACGCCATCGGGGCCCATATCGCCTATCCGGGGCCGCTGATCGTGATCGACTCGGGCACCGCCA
CCACCTTCGACGTGATCGCCGCCGACGGCGGGTTCGAGGGCGGGGTGATCGCGCCGGGGATCAACCTGTCCATGGAGGCG
TTGCACACGGCGGCGGCGAAACTTCCCAGGGTCGCGATCCAGAAGCCGCAGAAAGTCGTGGGGACGGATACGGTGGGCGC
GATGCAGGCCGGCGTGTTCTGGGGCTACATCGCCCTGATCGAGGGCCTGATCGCCCGCATCAAGGCCGAGCGGGACGAGC
CGCTGACCGTGGTGGCGACGGGCGGCGTCGCCTCGCTCTTCCACGGCGCGACCGCGGCCATCGACAAGTTCGACCCCGAC
CTCACCATCCGCGGCATGCTGGAGATCTGGCGCCGCAACCAGGCGAAGGCGTGA

Upstream 100 bases:

>100_bases
AGGCGCTGGATTCCGACGGCGCGCTGCGGCTCAGGCTGGACGACGGGAGCCTGGAGCGCATAACGGCGGGCGACGTGTTC
TTCGGGGGCGTGTGAGACGA

Downstream 100 bases:

>100_bases
TGGCGCGTAACAAGGACACCGACGAACTCGTCTTCCTGCCGCTGGGCGGGTCGAACGAGATCGGCATGAACTTCAACCTC
TACGGCTTCGGCCCGGCGCA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLLAIEQGNTNTLFAVHDGERWIAQWRAATDSTRTADEYAVWLSQLLSMAGLALGAFDGCIISSVVPQSIFNLRNLSRRY
LHVEPLVIGENAELGIPIRIDKPSEAGADRLVNAIGAHIAYPGPLIVIDSGTATTFDVIAADGGFEGGVIAPGINLSMEA
LHTAAAKLPRVAIQKPQKVVGTDTVGAMQAGVFWGYIALIEGLIARIKAERDEPLTVVATGGVASLFHGATAAIDKFDPD
LTIRGMLEIWRRNQAKA

Sequences:

>Translated_257_residues
MLLAIEQGNTNTLFAVHDGERWIAQWRAATDSTRTADEYAVWLSQLLSMAGLALGAFDGCIISSVVPQSIFNLRNLSRRY
LHVEPLVIGENAELGIPIRIDKPSEAGADRLVNAIGAHIAYPGPLIVIDSGTATTFDVIAADGGFEGGVIAPGINLSMEA
LHTAAAKLPRVAIQKPQKVVGTDTVGAMQAGVFWGYIALIEGLIARIKAERDEPLTVVATGGVASLFHGATAAIDKFDPD
LTIRGMLEIWRRNQAKA
>Mature_257_residues
MLLAIEQGNTNTLFAVHDGERWIAQWRAATDSTRTADEYAVWLSQLLSMAGLALGAFDGCIISSVVPQSIFNLRNLSRRY
LHVEPLVIGENAELGIPIRIDKPSEAGADRLVNAIGAHIAYPGPLIVIDSGTATTFDVIAADGGFEGGVIAPGINLSMEA
LHTAAAKLPRVAIQKPQKVVGTDTVGAMQAGVFWGYIALIEGLIARIKAERDEPLTVVATGGVASLFHGATAAIDKFDPD
LTIRGMLEIWRRNQAKA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_PHEZH (B4RC03)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130629.1
- GeneID:   6791302
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1789
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27351; Mature: 27351

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAIEQGNTNTLFAVHDGERWIAQWRAATDSTRTADEYAVWLSQLLSMAGLALGAFDGC
CEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IISSVVPQSIFNLRNLSRRYLHVEPLVIGENAELGIPIRIDKPSEAGADRLVNAIGAHIA
HHHHHHHHHHHHHHHHHHHEEEECEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCC
YPGPLIVIDSGTATTFDVIAADGGFEGGVIAPGINLSMEALHTAAAKLPRVAIQKPQKVV
CCCCEEEEECCCCCEEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHCCHHHHCCCCHHH
GTDTVGAMQAGVFWGYIALIEGLIARIKAERDEPLTVVATGGVASLFHGATAAIDKFDPD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCHHHHHHCCCCC
LTIRGMLEIWRRNQAKA
EEHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLAIEQGNTNTLFAVHDGERWIAQWRAATDSTRTADEYAVWLSQLLSMAGLALGAFDGC
CEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IISSVVPQSIFNLRNLSRRYLHVEPLVIGENAELGIPIRIDKPSEAGADRLVNAIGAHIA
HHHHHHHHHHHHHHHHHHHEEEECEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCC
YPGPLIVIDSGTATTFDVIAADGGFEGGVIAPGINLSMEALHTAAAKLPRVAIQKPQKVV
CCCCEEEEECCCCCEEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHCCHHHHCCCCHHH
GTDTVGAMQAGVFWGYIALIEGLIARIKAERDEPLTVVATGGVASLFHGATAAIDKFDPD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCHHHHHHCCCCC
LTIRGMLEIWRRNQAKA
EEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA