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The map label for this gene is tig [H]

Identifier: 197105163

GI number: 197105163

Start: 1906276

End: 1907640

Strand: Reverse

Name: tig [H]

Synonym: PHZ_c1700

Alternate gene names: 197105163

Gene position: 1907640-1906276 (Counterclockwise)

Preceding gene: 197105165

Following gene: 197105161

Centisome position: 47.74

GC content: 66.23

Gene sequence:

>1365_bases
ATGTCGATGCAAGTCGTTGAGAAGTCTGGCGAAGGTCTGAGCCGAGTCTACGGCGTCACGGTCCCCGTGAAGGACCTGAA
CGATCGACTGGAAGCGCGGATCGCCGAGATCACGCCGACGCTCAACATCAAGGGCTTCCGCCCCGGCAAGGTGCCGCCGG
CGCACGTGAAGCGCCTGTACGGCAAGCAGCTGATGAGCGAAGTCCTCGAGGCGACCCTGTCCGAGACCACCCAGAAGGTG
CTGGAAGACAACAAGCTGCGTCCCGCGGGCGAGCCCGAGCTGAAGCCGGAAGGCGACCTGCAGGGCGTGATCGACGGCAA
GGCGGACCTGGCCTACGAGATCTCGGTCGACCTGATGCCCGAGTTCGAGCCGGTGGACCCCGCCACCCTGTCGCTGACCC
GGCCGGTCTACGAGCCCACCGACGCCGAGGTGGACGAGGCGGTCGAGGAACTGGCCAAGCAGAACCGCACCTACGAGACC
AAGACCGGCAAGACCGTGAAGGCCAAGGACGGCGACATGGTCGTCATCGACTTCGTCGGCCGGATCGACGGCGAGGCCTT
CGAGGGCGGCTCGGCCACCGACGTCGAGCTGGTGCTGGGCTCGGGTCAGTTCATCCCCGGCTTCGAGGACCAGCTGGTGG
GCGCCAAGCCCGACAGCGACGTCGAGGTGAAGGTGACCTTCCCGGCCGACTACCAGGCGGCCAACCTGGCCGGCAAGGAA
GCGGTCTTCGAGACCAAGGTGAAGGAAGTGAAGGCGCCGGCCGAGAGCAAGGCCGACGACGCCTTCGCCGAGCGTCTCGG
CGTCGAGAACCTCGAGAAGCTCAAGGAGCTGCTGAAGACCAACCTCGAGCAGCAGTACGCCGGCGCCAGCCGCTTCAAGC
TGAAGCGCGCCCTGCTGGACGAGCTGGATTCGAAGCACGACTTCCCGCTGCCGCCCAAGATGGTCGAGGCCGAGTTCGCC
TCGATCTGGAGCCAGGTCCAGCAGGACAAGGAAGCCGGCAACCTGCCTGAGGACGACGCCAAGAAGTCCGACGAGCAGCT
CGAGTCCGAGTACCGCAAGATCGCCGAGCGCCGCGTGCGCCTGGGCCTGGTGCTGGCCGAGATCGGCCGGGCCAACAACG
TCCAGGTCACCGATCAGGAACTGGGCGAGGCGATCCGCCGCGAGGCGATCAAGTACGGCCCGCAGGCCCAGCAGGTGTTC
GAACTGCTGCGCCAGAATCCCAACGCCCAGGCGCAGCTGCGCGCCCCGATCTTCGAGGACAAGGTCGTCGACCTGATCGT
CGAGAAGGCCAAGGTGGAGGACAAGAAGGTCGACAAGGACGAGCTCCTCAAGGAGGACGACCTGCCGGCCGGCTACGAGG
GCTAA

Upstream 100 bases:

>100_bases
AAGGGCGCGCCGCGCCGCCGGGCGATTTCGGCGGCGCTCCCTATTCCACCTGAAGGCGGACCCTCAGCGCGCGCCTGGCG
CGTCGTCCGGAAGTTGAAGA

Downstream 100 bases:

>100_bases
GCCCCTCGACCGAAGAGAGATTGCAGGCGGCGCCGCACCGGAAGGGGCGGCGCCGTTTTCCTTATCTGGGATCAGTCTTC
CAGGGTGTAGCCCAGCTTCA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSMQVVEKSGEGLSRVYGVTVPVKDLNDRLEARIAEITPTLNIKGFRPGKVPPAHVKRLYGKQLMSEVLEATLSETTQKV
LEDNKLRPAGEPELKPEGDLQGVIDGKADLAYEISVDLMPEFEPVDPATLSLTRPVYEPTDAEVDEAVEELAKQNRTYET
KTGKTVKAKDGDMVVIDFVGRIDGEAFEGGSATDVELVLGSGQFIPGFEDQLVGAKPDSDVEVKVTFPADYQAANLAGKE
AVFETKVKEVKAPAESKADDAFAERLGVENLEKLKELLKTNLEQQYAGASRFKLKRALLDELDSKHDFPLPPKMVEAEFA
SIWSQVQQDKEAGNLPEDDAKKSDEQLESEYRKIAERRVRLGLVLAEIGRANNVQVTDQELGEAIRREAIKYGPQAQQVF
ELLRQNPNAQAQLRAPIFEDKVVDLIVEKAKVEDKKVDKDELLKEDDLPAGYEG

Sequences:

>Translated_454_residues
MSMQVVEKSGEGLSRVYGVTVPVKDLNDRLEARIAEITPTLNIKGFRPGKVPPAHVKRLYGKQLMSEVLEATLSETTQKV
LEDNKLRPAGEPELKPEGDLQGVIDGKADLAYEISVDLMPEFEPVDPATLSLTRPVYEPTDAEVDEAVEELAKQNRTYET
KTGKTVKAKDGDMVVIDFVGRIDGEAFEGGSATDVELVLGSGQFIPGFEDQLVGAKPDSDVEVKVTFPADYQAANLAGKE
AVFETKVKEVKAPAESKADDAFAERLGVENLEKLKELLKTNLEQQYAGASRFKLKRALLDELDSKHDFPLPPKMVEAEFA
SIWSQVQQDKEAGNLPEDDAKKSDEQLESEYRKIAERRVRLGLVLAEIGRANNVQVTDQELGEAIRREAIKYGPQAQQVF
ELLRQNPNAQAQLRAPIFEDKVVDLIVEKAKVEDKKVDKDELLKEDDLPAGYEG
>Mature_453_residues
SMQVVEKSGEGLSRVYGVTVPVKDLNDRLEARIAEITPTLNIKGFRPGKVPPAHVKRLYGKQLMSEVLEATLSETTQKVL
EDNKLRPAGEPELKPEGDLQGVIDGKADLAYEISVDLMPEFEPVDPATLSLTRPVYEPTDAEVDEAVEELAKQNRTYETK
TGKTVKAKDGDMVVIDFVGRIDGEAFEGGSATDVELVLGSGQFIPGFEDQLVGAKPDSDVEVKVTFPADYQAANLAGKEA
VFETKVKEVKAPAESKADDAFAERLGVENLEKLKELLKTNLEQQYAGASRFKLKRALLDELDSKHDFPLPPKMVEAEFAS
IWSQVQQDKEAGNLPEDDAKKSDEQLESEYRKIAERRVRLGLVLAEIGRANNVQVTDQELGEAIRREAIKYGPQAQQVFE
LLRQNPNAQAQLRAPIFEDKVVDLIVEKAKVEDKKVDKDELLKEDDLPAGYEG

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=445, Percent_Identity=30.561797752809, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 50246; Mature: 50115

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMQVVEKSGEGLSRVYGVTVPVKDLNDRLEARIAEITPTLNIKGFRPGKVPPAHVKRLY
CCCHHHHHCCCCCHHHEECEEEHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
GKQLMSEVLEATLSETTQKVLEDNKLRPAGEPELKPEGDLQGVIDGKADLAYEISVDLMP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCC
EFEPVDPATLSLTRPVYEPTDAEVDEAVEELAKQNRTYETKTGKTVKAKDGDMVVIDFVG
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCCEEEECCCCEEEEEECC
RIDGEAFEGGSATDVELVLGSGQFIPGFEDQLVGAKPDSDVEVKVTFPADYQAANLAGKE
CCCCCCCCCCCCCEEEEEEECCCCCCCCHHCCCCCCCCCCEEEEEECCCCCCHHHCCCHH
AVFETKVKEVKAPAESKADDAFAERLGVENLEKLKELLKTNLEQQYAGASRFKLKRALLD
HHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELDSKHDFPLPPKMVEAEFASIWSQVQQDKEAGNLPEDDAKKSDEQLESEYRKIAERRVR
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGLVLAEIGRANNVQVTDQELGEAIRREAIKYGPQAQQVFELLRQNPNAQAQLRAPIFED
HHHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCHHH
KVVDLIVEKAKVEDKKVDKDELLKEDDLPAGYEG
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SMQVVEKSGEGLSRVYGVTVPVKDLNDRLEARIAEITPTLNIKGFRPGKVPPAHVKRLY
CCHHHHHCCCCCHHHEECEEEHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHH
GKQLMSEVLEATLSETTQKVLEDNKLRPAGEPELKPEGDLQGVIDGKADLAYEISVDLMP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEECCC
EFEPVDPATLSLTRPVYEPTDAEVDEAVEELAKQNRTYETKTGKTVKAKDGDMVVIDFVG
CCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCEECCCCCEEEECCCCEEEEEECC
RIDGEAFEGGSATDVELVLGSGQFIPGFEDQLVGAKPDSDVEVKVTFPADYQAANLAGKE
CCCCCCCCCCCCCEEEEEEECCCCCCCCHHCCCCCCCCCCEEEEEECCCCCCHHHCCCHH
AVFETKVKEVKAPAESKADDAFAERLGVENLEKLKELLKTNLEQQYAGASRFKLKRALLD
HHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELDSKHDFPLPPKMVEAEFASIWSQVQQDKEAGNLPEDDAKKSDEQLESEYRKIAERRVR
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGLVLAEIGRANNVQVTDQELGEAIRREAIKYGPQAQQVFELLRQNPNAQAQLRAPIFED
HHHHHHHHCCCCCCEECHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCHHH
KVVDLIVEKAKVEDKKVDKDELLKEDDLPAGYEG
HHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA