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The map label for this gene is nrdR

Identifier: 197105137

GI number: 197105137

Start: 1878597

End: 1879064

Strand: Reverse

Name: nrdR

Synonym: PHZ_c1674

Alternate gene names: 197105137

Gene position: 1879064-1878597 (Counterclockwise)

Preceding gene: 197105138

Following gene: 197105134

Centisome position: 47.02

GC content: 68.59

Gene sequence:

>468_bases
ATGCGCTGCCCGTTCTGCGGCCACGACGAGACCCAGGTGAAGGACAGCCGCCCGTCGGAAGACGGCGCGGCCATCCGGCG
CAGGCGGCTGTGCCCGCAGTGCGAAGGCCGCTTCACGACCTTCGAGCGCGTGCAGCTGCGCGAGATCACCATCCTGAAGC
GGTCGGGCCGGCGCACGCCCTTCGACCGGGACAAGCTGGCCCGGTCCATCTCCATCGCCCTGCGCAAGCGGCCGGTGGAG
CCCGAGCGGATCGAGCGGATGATCTCGACCATCGTCCGCCAGCTCGAGAGCATGGGCGAAACCGAGCTGCCGTCCTCGAC
CATCGGCGAGCTGGTGATGAAGCAGCTCAAGCAGCTCGATGACGTGGCCTATGTCCGCTACGCCTCGGTGTACCGCGACT
TCCGCGAGACCCAGGACTTCGCCCGGTTCCTGGGCGAGGAAGGCCTGAGCGAGGCCGCCGAATCCTGA

Upstream 100 bases:

>100_bases
ACGCCGGTCGAACAGAAGGTGCGCGGCGAGGTGCTGGCGCTGACGAAGCGCTTCCCCATCTACAGCTAATAGCGTTAAGT
GGTCGGGAAGGGGGCTAGAT

Downstream 100 bases:

>100_bases
CGGAAGAGTCCTGACGAAGAGCGCCGGCCGGCTCGGGTATTCCTGCCGGCGCTCCCGTCGTCGCGGGCCTAACAGAAGGC
CGGCGCAACCTCTTCCAGCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MRCPFCGHDETQVKDSRPSEDGAAIRRRRLCPQCEGRFTTFERVQLREITILKRSGRRTPFDRDKLARSISIALRKRPVE
PERIERMISTIVRQLESMGETELPSSTIGELVMKQLKQLDDVAYVRYASVYRDFRETQDFARFLGEEGLSEAAES

Sequences:

>Translated_155_residues
MRCPFCGHDETQVKDSRPSEDGAAIRRRRLCPQCEGRFTTFERVQLREITILKRSGRRTPFDRDKLARSISIALRKRPVE
PERIERMISTIVRQLESMGETELPSSTIGELVMKQLKQLDDVAYVRYASVYRDFRETQDFARFLGEEGLSEAAES
>Mature_155_residues
MRCPFCGHDETQVKDSRPSEDGAAIRRRRLCPQCEGRFTTFERVQLREITILKRSGRRTPFDRDKLARSISIALRKRPVE
PERIERMISTIVRQLESMGETELPSSTIGELVMKQLKQLDDVAYVRYASVYRDFRETQDFARFLGEEGLSEAAES

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=141, Percent_Identity=47.5177304964539, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_PHEZH (B4RB34)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130514.1
- GeneID:   6791186
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1674
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18002; Mature: 18002

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGHDETQVKDSRPSEDGAAIRRRRLCPQCEGRFTTFERVQLREITILKRSGRRTP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLARSISIALRKRPVEPERIERMISTIVRQLESMGETELPSSTIGELVMKQLKQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
DVAYVRYASVYRDFRETQDFARFLGEEGLSEAAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRCPFCGHDETQVKDSRPSEDGAAIRRRRLCPQCEGRFTTFERVQLREITILKRSGRRTP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLARSISIALRKRPVEPERIERMISTIVRQLESMGETELPSSTIGELVMKQLKQLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
DVAYVRYASVYRDFRETQDFARFLGEEGLSEAAES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA