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The map label for this gene is thiL [H]

Identifier: 197105130

GI number: 197105130

Start: 1873071

End: 1874021

Strand: Reverse

Name: thiL [H]

Synonym: PHZ_c1667

Alternate gene names: 197105130

Gene position: 1874021-1873071 (Counterclockwise)

Preceding gene: 197105131

Following gene: 197105128

Centisome position: 46.89

GC content: 74.66

Gene sequence:

>951_bases
ATGTCCGGCCTGGATGAGTTCGGCGAGATCGCAAGGCTCTTCCGCCCGCTGACCCGCGGGGCTCCCGGCGCGTTCGAGCT
CAAGGACGACGCCGCCGTCATTCCCTCCCGGCCGGGGTTCGACCTGGTGGTCACCAAGGACGCCGTGGTCGAGGGCGTCC
ACGTGCCGAAGGGCGAGGCGCCCGACCTGATCGCGCGCAAGCTGGTGCGGGTGAACCTGTCGGACCTGGCCGCCAAGGGC
GCCGAGCCGGCGGGGTGCCTGCTGGCCGTCGCCTGGCCGCGCGCCTATCGCCTGAAGGACCGGGAACGGTTCGTCCTGGG
CCTGGCCGCCGATCTCGAGACCTACGCCTTGCCGCTGCTGGGCGGGGACACCGTGGCCATGCCGGACGGTCCGCTCACCG
CCAGCCTGACCGCCTTCGGCTGGGTCCCGGAGGGGCGGATGCTGCGCCGCGGCGGCGCCCGCCCGGGGGACCTCGTCCTG
GTCAGCGGAGCGATCGGGGACGCGACCCTGGGCCTGGCCGCGGTCCAGGGCGAGATCGAGGATCCCGACGGCTCGCTGAC
CTATCGCTACCGGCTGCCCGAACCGCGGCTGGACGTGCGGGCGGCGCTGCGCCGCACCGCCACCGCCACGGCCGACATCT
CGGACGGGTTGATCGCCGACGCCCGCCACATCGCCGAGGCCAGCGAGGTGGCGATCACCCTCGACCTCGAGCAGATGCCG
CTCTCCCGCGCGGCGGCCACCTGGCTGGAGGGGCAGCCCGACACCACCGCCGCCCTGCTGCGCCTCGCCTCGGGCGGGGA
CGACTACGAGATCGTCTGCACCGTTCCGTCGGGGGTTCGCAAGCCGGCCGGCTTCACCGTCGTGGGCAGGGTTTCGGAGG
GGGCGGGCGTGGAGGTCCGCGCGCTGGGCCGCACACTGGAGGCCGGAGCCGGGGGCTGGCGGCACGGCTGA

Upstream 100 bases:

>100_bases
ACCGAGGTGGCGATCGACGAGTACGTCGAGCTGACGAAGAGCTTCTTCGAGGGACCCGAACCGGGCTTCGTGAACGGGGC
CCTGGACGGCGTGGCGCGGG

Downstream 100 bases:

>100_bases
GGCCGCGCGGGGCTAGATGTACTCGAAGCGCACGGTGGACCGGCCGAAGTCCAACGCCACCTGCTCGAACTGCATCAGGA
GGTCCATGCCGAGCACCAGC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSGLDEFGEIARLFRPLTRGAPGAFELKDDAAVIPSRPGFDLVVTKDAVVEGVHVPKGEAPDLIARKLVRVNLSDLAAKG
AEPAGCLLAVAWPRAYRLKDRERFVLGLAADLETYALPLLGGDTVAMPDGPLTASLTAFGWVPEGRMLRRGGARPGDLVL
VSGAIGDATLGLAAVQGEIEDPDGSLTYRYRLPEPRLDVRAALRRTATATADISDGLIADARHIAEASEVAITLDLEQMP
LSRAAATWLEGQPDTTAALLRLASGGDDYEIVCTVPSGVRKPAGFTVVGRVSEGAGVEVRALGRTLEAGAGGWRHG

Sequences:

>Translated_316_residues
MSGLDEFGEIARLFRPLTRGAPGAFELKDDAAVIPSRPGFDLVVTKDAVVEGVHVPKGEAPDLIARKLVRVNLSDLAAKG
AEPAGCLLAVAWPRAYRLKDRERFVLGLAADLETYALPLLGGDTVAMPDGPLTASLTAFGWVPEGRMLRRGGARPGDLVL
VSGAIGDATLGLAAVQGEIEDPDGSLTYRYRLPEPRLDVRAALRRTATATADISDGLIADARHIAEASEVAITLDLEQMP
LSRAAATWLEGQPDTTAALLRLASGGDDYEIVCTVPSGVRKPAGFTVVGRVSEGAGVEVRALGRTLEAGAGGWRHG
>Mature_315_residues
SGLDEFGEIARLFRPLTRGAPGAFELKDDAAVIPSRPGFDLVVTKDAVVEGVHVPKGEAPDLIARKLVRVNLSDLAAKGA
EPAGCLLAVAWPRAYRLKDRERFVLGLAADLETYALPLLGGDTVAMPDGPLTASLTAFGWVPEGRMLRRGGARPGDLVLV
SGAIGDATLGLAAVQGEIEDPDGSLTYRYRLPEPRLDVRAALRRTATATADISDGLIADARHIAEASEVAITLDLEQMPL
SRAAATWLEGQPDTTAALLRLASGGDDYEIVCTVPSGVRKPAGFTVVGRVSEGAGVEVRALGRTLEAGAGGWRHG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=276, Percent_Identity=38.0434782608696, Blast_Score=141, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 33131; Mature: 33000

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLDEFGEIARLFRPLTRGAPGAFELKDDAAVIPSRPGFDLVVTKDAVVEGVHVPKGEA
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCCCCCEEEEECHHHHCCCCCCCCCC
PDLIARKLVRVNLSDLAAKGAEPAGCLLAVAWPRAYRLKDRERFVLGLAADLETYALPLL
HHHHHHHHHHCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEE
GGDTVAMPDGPLTASLTAFGWVPEGRMLRRGGARPGDLVLVSGAIGDATLGLAAVQGEIE
CCCEEECCCCCCEEEEEEEECCCCCHHHHCCCCCCCCEEEEECCCCCHHHEEEEEECCCC
DPDGSLTYRYRLPEPRLDVRAALRRTATATADISDGLIADARHIAEASEVAITLDLEQMP
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCC
LSRAAATWLEGQPDTTAALLRLASGGDDYEIVCTVPSGVRKPAGFTVVGRVSEGAGVEVR
HHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCEEEE
ALGRTLEAGAGGWRHG
ECCCCHHCCCCCCCCC
>Mature Secondary Structure 
SGLDEFGEIARLFRPLTRGAPGAFELKDDAAVIPSRPGFDLVVTKDAVVEGVHVPKGEA
CCHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCCCCCEEEEECHHHHCCCCCCCCCC
PDLIARKLVRVNLSDLAAKGAEPAGCLLAVAWPRAYRLKDRERFVLGLAADLETYALPLL
HHHHHHHHHHCCHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEE
GGDTVAMPDGPLTASLTAFGWVPEGRMLRRGGARPGDLVLVSGAIGDATLGLAAVQGEIE
CCCEEECCCCCCEEEEEEEECCCCCHHHHCCCCCCCCEEEEECCCCCHHHEEEEEECCCC
DPDGSLTYRYRLPEPRLDVRAALRRTATATADISDGLIADARHIAEASEVAITLDLEQMP
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHCC
LSRAAATWLEGQPDTTAALLRLASGGDDYEIVCTVPSGVRKPAGFTVVGRVSEGAGVEVR
HHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCEEEE
ALGRTLEAGAGGWRHG
ECCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]