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The map label for this gene is fabH [H]

Identifier: 197105122

GI number: 197105122

Start: 1865361

End: 1866341

Strand: Reverse

Name: fabH [H]

Synonym: PHZ_c1659

Alternate gene names: 197105122

Gene position: 1866341-1865361 (Counterclockwise)

Preceding gene: 197105123

Following gene: 197105121

Centisome position: 46.7

GC content: 72.68

Gene sequence:

>981_bases
GTGCCCAAGGTCCTGCGTAGCGTCGTCACCGGCGTCGGCGGCTATCTGCCGGAACGGATCGTCACGAACGACGACCTGGC
CAAGATCGTCGAGACCTCCGACGAGTGGATCCGCGAGCGGACCGGCATCCGCCAGCGCCGCCAGGCCGAGGACGACCAGC
CGGTCTCCGACCTGGCCGTCGAGGCCGCCCGGCGCGCCCTGGCCGCCGCGGGCCGATCGCCCGACGACGTCGACCTCATT
GTGGTGGCCACCACCACGCCCGACCTGACCTTCCCGGCCACCGCCGCCATCGTCCAGCGCAAGCTGGGCGCGCCTGTCGG
CATCGCCTTTGACGTGCAGGCGGTCTGCTCGGGCTTCGTCTACGCGCTCTCCGTGGCCGACGGCTTCGTGGCCCGCCGCC
GGGCCAAGTGCGCACTGGTCATCGGCGCCGAGTGCATGACCCGCCTGATGGACTGGACCGACCGGGGCACCTGCGTGCTG
TTCGGCGACGGCGCCGGGGCGGTCGTGCTGGAGCCGGGCGAGGGCGAGGGGGCGGTCGCCGACCGCGGACTCCTGGGCTT
CGCCCTGCGCGCCGACGGGACCAAGCAGGACCTGCTCTACGTGGACGGCGGCGTCTCCACGACCCGCACGACGGGCTACC
TGCGGATGCAGGGCAACCAGGTCTTCCGCCACGCGGTGGTGAACATCTCCGAGGCGGTGGTCGCCGCGGCCGCCGACGCC
GGCGTCGAGGTCTCGGCCGTGGACTGGTTCATCCCGCACCAGGCCAACCAGCGCATCCTGGAGGGCGTCGCCAGGCGCCT
GGGCATCGACGAGACCAAGGTCATCTCGACCGTGGCCGAGCACGCCAACACCTCGGCGGCCTCGATCCCGCTGGCGCTCG
ACCAAGGCGTGCAGGACGGGCGAATCAAGCCGGGGCAGCTGCTGCTTCTGGAGGCGATGGGCGGCGGCCTGACCTGGGGG
GCGTGCGTCCTGCGCCTCTAG

Upstream 100 bases:

>100_bases
GGCGCAAAGCGGGTTTGCCTCGGAGATCGAACGGAATATGAGGCGGCTTCCCGCCGCGCTTTCCCCTGCGGCGCCTTCGC
CTGCCGATGGAGCCGCCTGA

Downstream 100 bases:

>100_bases
CGCTTAACCACCGCCCGCAAAGCGTGACTTGAAGTCTTTGAGCCGATAGGACAATCAAGGTCCATGAACGATGTCTCGTC
GGGGGTCAGCGCAAGGATGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MPKVLRSVVTGVGGYLPERIVTNDDLAKIVETSDEWIRERTGIRQRRQAEDDQPVSDLAVEAARRALAAAGRSPDDVDLI
VVATTTPDLTFPATAAIVQRKLGAPVGIAFDVQAVCSGFVYALSVADGFVARRRAKCALVIGAECMTRLMDWTDRGTCVL
FGDGAGAVVLEPGEGEGAVADRGLLGFALRADGTKQDLLYVDGGVSTTRTTGYLRMQGNQVFRHAVVNISEAVVAAAADA
GVEVSAVDWFIPHQANQRILEGVARRLGIDETKVISTVAEHANTSAASIPLALDQGVQDGRIKPGQLLLLEAMGGGLTWG
ACVLRL

Sequences:

>Translated_326_residues
MPKVLRSVVTGVGGYLPERIVTNDDLAKIVETSDEWIRERTGIRQRRQAEDDQPVSDLAVEAARRALAAAGRSPDDVDLI
VVATTTPDLTFPATAAIVQRKLGAPVGIAFDVQAVCSGFVYALSVADGFVARRRAKCALVIGAECMTRLMDWTDRGTCVL
FGDGAGAVVLEPGEGEGAVADRGLLGFALRADGTKQDLLYVDGGVSTTRTTGYLRMQGNQVFRHAVVNISEAVVAAAADA
GVEVSAVDWFIPHQANQRILEGVARRLGIDETKVISTVAEHANTSAASIPLALDQGVQDGRIKPGQLLLLEAMGGGLTWG
ACVLRL
>Mature_325_residues
PKVLRSVVTGVGGYLPERIVTNDDLAKIVETSDEWIRERTGIRQRRQAEDDQPVSDLAVEAARRALAAAGRSPDDVDLIV
VATTTPDLTFPATAAIVQRKLGAPVGIAFDVQAVCSGFVYALSVADGFVARRRAKCALVIGAECMTRLMDWTDRGTCVLF
GDGAGAVVLEPGEGEGAVADRGLLGFALRADGTKQDLLYVDGGVSTTRTTGYLRMQGNQVFRHAVVNISEAVVAAAADAG
VEVSAVDWFIPHQANQRILEGVARRLGIDETKVISTVAEHANTSAASIPLALDQGVQDGRIKPGQLLLLEAMGGGLTWGA
CVLRL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=46.4396284829721, Blast_Score=283, Evalue=8e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34433; Mature: 34301

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVLRSVVTGVGGYLPERIVTNDDLAKIVETSDEWIRERTGIRQRRQAEDDQPVSDLAV
CHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EAARRALAAAGRSPDDVDLIVVATTTPDLTFPATAAIVQRKLGAPVGIAFDVQAVCSGFV
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHH
YALSVADGFVARRRAKCALVIGAECMTRLMDWTDRGTCVLFGDGAGAVVLEPGEGEGAVA
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCEE
DRGLLGFALRADGTKQDLLYVDGGVSTTRTTGYLRMQGNQVFRHAVVNISEAVVAAAADA
CCCCEEEEEECCCCCCCEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
GVEVSAVDWFIPHQANQRILEGVARRLGIDETKVISTVAEHANTSAASIPLALDQGVQDG
CCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCHHHCCCCCC
RIKPGQLLLLEAMGGGLTWGACVLRL
CCCCCCEEEEEECCCCCCHHHHEECC
>Mature Secondary Structure 
PKVLRSVVTGVGGYLPERIVTNDDLAKIVETSDEWIRERTGIRQRRQAEDDQPVSDLAV
HHHHHHHHHHHCCCCCCHHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
EAARRALAAAGRSPDDVDLIVVATTTPDLTFPATAAIVQRKLGAPVGIAFDVQAVCSGFV
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHH
YALSVADGFVARRRAKCALVIGAECMTRLMDWTDRGTCVLFGDGAGAVVLEPGEGEGAVA
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCEE
DRGLLGFALRADGTKQDLLYVDGGVSTTRTTGYLRMQGNQVFRHAVVNISEAVVAAAADA
CCCCEEEEEECCCCCCCEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
GVEVSAVDWFIPHQANQRILEGVARRLGIDETKVISTVAEHANTSAASIPLALDQGVQDG
CCEEEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHCCCCHHHCCCCCC
RIKPGQLLLLEAMGGGLTWGACVLRL
CCCCCCEEEEEECCCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]