Click here to switch to the map view.

The map label for this gene is kdsA [H]

Identifier: 197105089

GI number: 197105089

Start: 1833590

End: 1834447

Strand: Reverse

Name: kdsA [H]

Synonym: PHZ_c1626

Alternate gene names: 197105089

Gene position: 1834447-1833590 (Counterclockwise)

Preceding gene: 197105093

Following gene: 197105088

Centisome position: 45.9

GC content: 71.45

Gene sequence:

>858_bases
ATGGCCGTCCTGAAGCTCGATCGCTGGAACCTCGCCATCGGCGACGGCCAGCCGCTGGTGGTGATCGCCGGGCTCAACGT
GCTGGAGGACGAGGCGCTGGCCCTGGCCACGGCCCGCCACCTGAAGGCGGCGTGCGAGCGGCTCCAGCTGCCGTTCGTGT
TCAAGGCCAGCTTCGACAAGGCGAACCGCTCGTCGATCAGCAGCTACCGCGGCCCTGGCCTGGAGGCGGGGCTCGCGATG
CTGAAGGCGGTGAAGGACCAGGTGGGCGTGCCGATCGCCACCGACATCCACGAGCCCGGCCAGGCCGGCCCACTGGCCGA
GGTGGTGGACCTGCTGCAGATCCCCGCCTTCCTGTGCCGTCAGACGGACCTCGTCGTCGCCTCCGCGCGGGCCATCCACG
CCGCCGGCGGCCTGCTGCACGTCAAGAAGGGCCAGTTCCTGGCGCCCTGGGACGCCAAGAACATCGTCTCCAAGGTGAAG
GAGGCCACGGGCGGCGCCGAAATCACCGTCCTTTGCGAGCGCGGCTCGTCCTTCGGCTACAACAACCTGGTCGTCGACAT
GCTCGGCATCGGCGAGATGAAGAAGCTGGGCTGCCCCGTGACCATCGACGCCACCCACGCGGTCCAACTCCCCGGCGCCG
ACCCGCGCACCGGCGGCGCCTCGACGGGCGGACGGCGCGAGGGCGTGGCGGTGATCGCCAGGGCCGCCGTCGTCTCCGGG
GCCGACGGGGTGTTCCTGGAGTTCCATCCCGACCCCGACAAGGCGCTCTGCGACGGGCCAAGCTGCCTGCCGCTGGACGG
CGCCGAGCCGCTGCTGCGCCAGCTCAAGGCGCTGCACGAGGTCGCCCGCGCGGCTTGA

Upstream 100 bases:

>100_bases
ACGGCCGCGGCTGGCCGGCGGATGCCGCGGGAGCGCGATCCGGGACTTGAGATCGGGGGCGCGGCGCCGCACTTAGGCCG
CCGCAGACGAGAGGAGCCCC

Downstream 100 bases:

>100_bases
CCGGCCCGCCAACGCGCCGCACACCCTGAGCCCCATGGATCTGGCCGCACTCCAGCACCTCCTCAGCGAGGTCCCGGGCA
AGCGCGTCGCCTGCGTGGGC

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MAVLKLDRWNLAIGDGQPLVVIAGLNVLEDEALALATARHLKAACERLQLPFVFKASFDKANRSSISSYRGPGLEAGLAM
LKAVKDQVGVPIATDIHEPGQAGPLAEVVDLLQIPAFLCRQTDLVVASARAIHAAGGLLHVKKGQFLAPWDAKNIVSKVK
EATGGAEITVLCERGSSFGYNNLVVDMLGIGEMKKLGCPVTIDATHAVQLPGADPRTGGASTGGRREGVAVIARAAVVSG
ADGVFLEFHPDPDKALCDGPSCLPLDGAEPLLRQLKALHEVARAA

Sequences:

>Translated_285_residues
MAVLKLDRWNLAIGDGQPLVVIAGLNVLEDEALALATARHLKAACERLQLPFVFKASFDKANRSSISSYRGPGLEAGLAM
LKAVKDQVGVPIATDIHEPGQAGPLAEVVDLLQIPAFLCRQTDLVVASARAIHAAGGLLHVKKGQFLAPWDAKNIVSKVK
EATGGAEITVLCERGSSFGYNNLVVDMLGIGEMKKLGCPVTIDATHAVQLPGADPRTGGASTGGRREGVAVIARAAVVSG
ADGVFLEFHPDPDKALCDGPSCLPLDGAEPLLRQLKALHEVARAA
>Mature_284_residues
AVLKLDRWNLAIGDGQPLVVIAGLNVLEDEALALATARHLKAACERLQLPFVFKASFDKANRSSISSYRGPGLEAGLAML
KAVKDQVGVPIATDIHEPGQAGPLAEVVDLLQIPAFLCRQTDLVVASARAIHAAGGLLHVKKGQFLAPWDAKNIVSKVKE
ATGGAEITVLCERGSSFGYNNLVVDMLGIGEMKKLGCPVTIDATHAVQLPGADPRTGGASTGGRREGVAVIARAAVVSGA
DGVFLEFHPDPDKALCDGPSCLPLDGAEPLLRQLKALHEVARAA

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=276, Percent_Identity=51.0869565217391, Blast_Score=275, Evalue=3e-75,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 29754; Mature: 29623

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLKLDRWNLAIGDGQPLVVIAGLNVLEDEALALATARHLKAACERLQLPFVFKASFDK
CCEEEEECCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ANRSSISSYRGPGLEAGLAMLKAVKDQVGVPIATDIHEPGQAGPLAEVVDLLQIPAFLCR
CCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHC
QTDLVVASARAIHAAGGLLHVKKGQFLAPWDAKNIVSKVKEATGGAEITVLCERGSSFGY
CCCCEEHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCC
NNLVVDMLGIGEMKKLGCPVTIDATHAVQLPGADPRTGGASTGGRREGVAVIARAAVVSG
CCEEEEECCCCCHHHCCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
ADGVFLEFHPDPDKALCDGPSCLPLDGAEPLLRQLKALHEVARAA
CCCEEEEECCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVLKLDRWNLAIGDGQPLVVIAGLNVLEDEALALATARHLKAACERLQLPFVFKASFDK
CEEEEECCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ANRSSISSYRGPGLEAGLAMLKAVKDQVGVPIATDIHEPGQAGPLAEVVDLLQIPAFLCR
CCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHC
QTDLVVASARAIHAAGGLLHVKKGQFLAPWDAKNIVSKVKEATGGAEITVLCERGSSFGY
CCCCEEHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCC
NNLVVDMLGIGEMKKLGCPVTIDATHAVQLPGADPRTGGASTGGRREGVAVIARAAVVSG
CCEEEEECCCCCHHHCCCCEEECCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
ADGVFLEFHPDPDKALCDGPSCLPLDGAEPLLRQLKALHEVARAA
CCCEEEEECCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA