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The map label for this gene is ctaD [H]

Identifier: 197105048

GI number: 197105048

Start: 1786469

End: 1789003

Strand: Reverse

Name: ctaD [H]

Synonym: PHZ_c1585

Alternate gene names: 197105048

Gene position: 1789003-1786469 (Counterclockwise)

Preceding gene: 197105049

Following gene: 197105047

Centisome position: 44.77

GC content: 70.22

Gene sequence:

>2535_bases
ATGAGCTCCGAGACGGGCTTCGACCCGAAGCTCTTCGAGCGCTTCCCCACCCGCGAGCCGCGCCCCGAAGGCGAGTTCGA
GACCCTGAAGCACGTCTGGCGCGCGCCCACGGGCTGGGCGCGTCTGACCGTCGTCAACAACAACTACATCGGCCTCTACT
ACGTCGGCGCCGCCTTCCTGTTCTTCTGCCTGGCCGGGGTGTTGGCGCTGATCATGCGCGTCCAGCTGGCCCTGCCGCTG
AACGGGATCCTGCCGCAGGAGACCTACAACCAGGTCTTCACCATGCACGGCACGGTGATGATGTTCCTCTTCGCCGTCCC
GGCGGTGGAGGCGGCCGGCGTGCTGCTGCTGCCCCAGATGCTGTCGGCGCGCGACCTGCCGTTCCCGCGGCTCTCGGCCT
ACGCGTTCTGGGCCTATCTGGTGGGCGGACTGTGCTTCTTCGCCTCGATCTTCTTCGGCCTCGCCCCCGACGGCGGCTGG
TTCATGTACCCGCCGCTGACCAGCAAGACCTACTCGCCCGGGATCAACGCCGACTTCTGGCTCCTCGGCATCGGCTTCAT
CGAGATCAGCGCCATCGCCGGGGCCATCGAGATCATCGTCGGCGTGCTCAAGACCCGCGCCCCGGGCATGACCCTCGACA
AGCTGCCGATCTTCGCCTGGGCCATGCTGGTGTTCGCGGCGATGATCATCATCGGCTTCCCGGCGGTGATCCTGGGCACC
CTGCTGCTCGAGCTGGAGCGGGCGCTGAACTGGCCCTTCTTCGACCCCACGCGCGGGGGCGACCCGATGCTGTGGCAGCA
CCTGTTCTGGTTCTTCGGCCACCCCGAGGTCTACATCATCTTCCTGCCCGCCGCGGGGATGATGTCGATGATCGTTCCCG
CCGTCGTCCAGGCGCGGCTCATCGGCTACCGGCTCGTGGTGCTGGCCCTGCTGGCCACCGGCTTCATCAGCTTCGGCGTC
TGGGCCCACCACATGTTCGCCACCGGCATGCCGACCATCTCGGTCAGCTTCTTCTCGGCGGCCAGCATGGCGGTCAGCGT
GCCGGCCGGGGTGCAGGTCTTCGCCTGGATCGCGACCCTCGCCTCGGGAAAGATCCGCTGGAGCACGCCGGCCCTGTTCG
CCGTGGGCTCGATCGTCACCTTCACCATGGGCGGCCTGACCGGCGTCATGGTCGGCATGGTGCCGTTCGACTGGCAGGTC
CACGACACCTACTTCATCGTCGCCCACCTGCACTACGTGCTGATCGGCGGGATGGTCTTCCCGCTGTTCGCCGCCTTCTA
CTACTGGACCCCGATGATGAGCCGGCGGCCGCTGTCCGAGCGGTGGGGCCGGTGGGTCTTCGCCCTCATCTTCCTCGGCA
CGCACGTCAGCTTCCTGCCCATGCACCTGACCGGCCTGATGGGCATGCCCCGCCGGGTCTACACCTACCTGCCCGGCCGG
GACTGGGAGCTCACCAACCTCATCTCCACCGTCGGCGCCTTCATGATCGGCGCGGGCGTGCTGCTCTTCATCCTGGACCT
CGCGCGCAATTTCCGGGTGGCGGTCGAGGACAACGCCGGCAACGTCTACGGCGGCGGGACGCTCGAGTGGCTGCCCACGG
GGCTCTACTCCACCCGCTCGATCCCCGTGGTGCGCAGCGCCTATCCGCTGTGGGACGACCCGGACCTGCCGCGCGACGTC
GAGGCCGGCCGCTACTTCCTGCCCGGCAGCGCCACGGGCCTGCGCGAGACCCTCGTCACCAGCCCCATCCGGGCCGAGCC
GCAGTACCTTCAGCGCATGCCGGGCCCGTCGGTCTGGCCCCTGCTCGCCGCCGTCTTCACCGCGGGCTTCTTCATGCTGC
TCACGGTCCAGGCCTACTGGCCGGGCGTCGTCAGCGGCGTCCTGGCGGTCGCCTGCGTGCTGCGCTGGCTGTGGGAGACG
GACTGGCCGATGGGCCCGGCCAGCGTCGACATCGGCGCGGGCGTGCGCGTGCCCACCTATGTCACGGGCCCAGCCAGCCA
CGGCTGGTGGGCCATGGTCATCCTGCTGGTGGTGGCCGGCATGATCTTCCTGATGGCGTGCTTCAGCTACGTCTTCCTGT
GGAGCCGGCGTCCGGATCTCTGGCTTCCGCCCCCCGATCTCGTCTGGCTCGCCGGCATCGTCCTCGCCTACGCCGCCGCC
GGGGGCCTGGCCTGGCTCGCCGCCAGGTCCGCCCGCACCGCGGGCCGCGGCGCCGGCGTCGCGGCGCTGCTCGCCGGCCT
CGCCACGATCCTCTGCCTCGCCGCCTGGGCGGCCGACCTGGGCAGCTGGCGGATGGCCGGCCTCGACCCGGCCGCCAGCG
GCCAGGGGGCCACGGTCTTCGCCCTGCTCGCCTTCCAGGGCGTGCTGCTGTCGGTCGTCGTCCTGATGGCCGGCTATCTG
GCGGCGCGCACGGTGCGCGGGCTGGTGGCGCCGGACCGCACCTCCACCGTCGACCTCGTCGCCCTGTTCATCGCCAACGC
CGCCGCCCAGGGGGCCATCGCCGCCCTGCTCGTGCGCCTGTTCCCCGGAGCCTGA

Upstream 100 bases:

>100_bases
CCGACAGCCAGGCGATCAAGCCGGGCAACCGCATGCCCGCCTACCGGATGCTGTCCGGCGGCGACCTGCGCGCGCTGGCC
GCCTACCTGGAAAGCCGCCG

Downstream 100 bases:

>100_bases
CCGTGGGACGCTGGATCCTCATGCTGGGCGGTATGAGCGTCTGGGCGGCGCACTTCATGGGCGTCTACGGGATCGCCAGC
GTCGCCGACGTGGCGGCCGA

Product: cytochrome c oxidase, subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 844; Mature: 843

Protein sequence:

>844_residues
MSSETGFDPKLFERFPTREPRPEGEFETLKHVWRAPTGWARLTVVNNNYIGLYYVGAAFLFFCLAGVLALIMRVQLALPL
NGILPQETYNQVFTMHGTVMMFLFAVPAVEAAGVLLLPQMLSARDLPFPRLSAYAFWAYLVGGLCFFASIFFGLAPDGGW
FMYPPLTSKTYSPGINADFWLLGIGFIEISAIAGAIEIIVGVLKTRAPGMTLDKLPIFAWAMLVFAAMIIIGFPAVILGT
LLLELERALNWPFFDPTRGGDPMLWQHLFWFFGHPEVYIIFLPAAGMMSMIVPAVVQARLIGYRLVVLALLATGFISFGV
WAHHMFATGMPTISVSFFSAASMAVSVPAGVQVFAWIATLASGKIRWSTPALFAVGSIVTFTMGGLTGVMVGMVPFDWQV
HDTYFIVAHLHYVLIGGMVFPLFAAFYYWTPMMSRRPLSERWGRWVFALIFLGTHVSFLPMHLTGLMGMPRRVYTYLPGR
DWELTNLISTVGAFMIGAGVLLFILDLARNFRVAVEDNAGNVYGGGTLEWLPTGLYSTRSIPVVRSAYPLWDDPDLPRDV
EAGRYFLPGSATGLRETLVTSPIRAEPQYLQRMPGPSVWPLLAAVFTAGFFMLLTVQAYWPGVVSGVLAVACVLRWLWET
DWPMGPASVDIGAGVRVPTYVTGPASHGWWAMVILLVVAGMIFLMACFSYVFLWSRRPDLWLPPPDLVWLAGIVLAYAAA
GGLAWLAARSARTAGRGAGVAALLAGLATILCLAAWAADLGSWRMAGLDPAASGQGATVFALLAFQGVLLSVVVLMAGYL
AARTVRGLVAPDRTSTVDLVALFIANAAAQGAIAALLVRLFPGA

Sequences:

>Translated_844_residues
MSSETGFDPKLFERFPTREPRPEGEFETLKHVWRAPTGWARLTVVNNNYIGLYYVGAAFLFFCLAGVLALIMRVQLALPL
NGILPQETYNQVFTMHGTVMMFLFAVPAVEAAGVLLLPQMLSARDLPFPRLSAYAFWAYLVGGLCFFASIFFGLAPDGGW
FMYPPLTSKTYSPGINADFWLLGIGFIEISAIAGAIEIIVGVLKTRAPGMTLDKLPIFAWAMLVFAAMIIIGFPAVILGT
LLLELERALNWPFFDPTRGGDPMLWQHLFWFFGHPEVYIIFLPAAGMMSMIVPAVVQARLIGYRLVVLALLATGFISFGV
WAHHMFATGMPTISVSFFSAASMAVSVPAGVQVFAWIATLASGKIRWSTPALFAVGSIVTFTMGGLTGVMVGMVPFDWQV
HDTYFIVAHLHYVLIGGMVFPLFAAFYYWTPMMSRRPLSERWGRWVFALIFLGTHVSFLPMHLTGLMGMPRRVYTYLPGR
DWELTNLISTVGAFMIGAGVLLFILDLARNFRVAVEDNAGNVYGGGTLEWLPTGLYSTRSIPVVRSAYPLWDDPDLPRDV
EAGRYFLPGSATGLRETLVTSPIRAEPQYLQRMPGPSVWPLLAAVFTAGFFMLLTVQAYWPGVVSGVLAVACVLRWLWET
DWPMGPASVDIGAGVRVPTYVTGPASHGWWAMVILLVVAGMIFLMACFSYVFLWSRRPDLWLPPPDLVWLAGIVLAYAAA
GGLAWLAARSARTAGRGAGVAALLAGLATILCLAAWAADLGSWRMAGLDPAASGQGATVFALLAFQGVLLSVVVLMAGYL
AARTVRGLVAPDRTSTVDLVALFIANAAAQGAIAALLVRLFPGA
>Mature_843_residues
SSETGFDPKLFERFPTREPRPEGEFETLKHVWRAPTGWARLTVVNNNYIGLYYVGAAFLFFCLAGVLALIMRVQLALPLN
GILPQETYNQVFTMHGTVMMFLFAVPAVEAAGVLLLPQMLSARDLPFPRLSAYAFWAYLVGGLCFFASIFFGLAPDGGWF
MYPPLTSKTYSPGINADFWLLGIGFIEISAIAGAIEIIVGVLKTRAPGMTLDKLPIFAWAMLVFAAMIIIGFPAVILGTL
LLELERALNWPFFDPTRGGDPMLWQHLFWFFGHPEVYIIFLPAAGMMSMIVPAVVQARLIGYRLVVLALLATGFISFGVW
AHHMFATGMPTISVSFFSAASMAVSVPAGVQVFAWIATLASGKIRWSTPALFAVGSIVTFTMGGLTGVMVGMVPFDWQVH
DTYFIVAHLHYVLIGGMVFPLFAAFYYWTPMMSRRPLSERWGRWVFALIFLGTHVSFLPMHLTGLMGMPRRVYTYLPGRD
WELTNLISTVGAFMIGAGVLLFILDLARNFRVAVEDNAGNVYGGGTLEWLPTGLYSTRSIPVVRSAYPLWDDPDLPRDVE
AGRYFLPGSATGLRETLVTSPIRAEPQYLQRMPGPSVWPLLAAVFTAGFFMLLTVQAYWPGVVSGVLAVACVLRWLWETD
WPMGPASVDIGAGVRVPTYVTGPASHGWWAMVILLVVAGMIFLMACFSYVFLWSRRPDLWLPPPDLVWLAGIVLAYAAAG
GLAWLAARSARTAGRGAGVAALLAGLATILCLAAWAADLGSWRMAGLDPAASGQGATVFALLAFQGVLLSVVVLMAGYLA
ARTVRGLVAPDRTSTVDLVALFIANAAAQGAIAALLVRLFPGA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=497, Percent_Identity=37.8269617706237, Blast_Score=310, Evalue=3e-84,
Organism=Escherichia coli, GI1786634, Length=522, Percent_Identity=35.4406130268199, Blast_Score=317, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6226519, Length=467, Percent_Identity=36.830835117773, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6226524, Length=310, Percent_Identity=35.1612903225806, Blast_Score=202, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6226523, Length=234, Percent_Identity=35.8974358974359, Blast_Score=130, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 91862; Mature: 91730

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSETGFDPKLFERFPTREPRPEGEFETLKHVWRAPTGWARLTVVNNNYIGLYYVGAAFL
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCEEEHHHHHHHHH
FFCLAGVLALIMRVQLALPLNGILPQETYNQVFTMHGTVMMFLFAVPAVEAAGVLLLPQM
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSARDLPFPRLSAYAFWAYLVGGLCFFASIFFGLAPDGGWFMYPPLTSKTYSPGINADFW
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCC
LLGIGFIEISAIAGAIEIIVGVLKTRAPGMTLDKLPIFAWAMLVFAAMIIIGFPAVILGT
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLELERALNWPFFDPTRGGDPMLWQHLFWFFGHPEVYIIFLPAAGMMSMIVPAVVQARL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHH
IGYRLVVLALLATGFISFGVWAHHMFATGMPTISVSFFSAASMAVSVPAGVQVFAWIATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHEECCCHHHHHHHHHHH
ASGKIRWSTPALFAVGSIVTFTMGGLTGVMVGMVPFDWQVHDTYFIVAHLHYVLIGGMVF
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHH
PLFAAFYYWTPMMSRRPLSERWGRWVFALIFLGTHVSFLPMHLTGLMGMPRRVYTYLPGR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCC
DWELTNLISTVGAFMIGAGVLLFILDLARNFRVAVEDNAGNVYGGGTLEWLPTGLYSTRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCC
IPVVRSAYPLWDDPDLPRDVEAGRYFLPGSATGLRETLVTSPIRAEPQYLQRMPGPSVWP
CCHHHCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCHHH
LLAAVFTAGFFMLLTVQAYWPGVVSGVLAVACVLRWLWETDWPMGPASVDIGAGVRVPTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEE
VTGPASHGWWAMVILLVVAGMIFLMACFSYVFLWSRRPDLWLPPPDLVWLAGIVLAYAAA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GGLAWLAARSARTAGRGAGVAALLAGLATILCLAAWAADLGSWRMAGLDPAASGQGATVF
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHH
ALLAFQGVLLSVVVLMAGYLAARTVRGLVAPDRTSTVDLVALFIANAAAQGAIAALLVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FPGA
CCCC
>Mature Secondary Structure 
SSETGFDPKLFERFPTREPRPEGEFETLKHVWRAPTGWARLTVVNNNYIGLYYVGAAFL
CCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCEEEHHHHHHHHH
FFCLAGVLALIMRVQLALPLNGILPQETYNQVFTMHGTVMMFLFAVPAVEAAGVLLLPQM
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LSARDLPFPRLSAYAFWAYLVGGLCFFASIFFGLAPDGGWFMYPPLTSKTYSPGINADFW
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCC
LLGIGFIEISAIAGAIEIIVGVLKTRAPGMTLDKLPIFAWAMLVFAAMIIIGFPAVILGT
EEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLELERALNWPFFDPTRGGDPMLWQHLFWFFGHPEVYIIFLPAAGMMSMIVPAVVQARL
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHH
IGYRLVVLALLATGFISFGVWAHHMFATGMPTISVSFFSAASMAVSVPAGVQVFAWIATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHEECCCHHHHHHHHHHH
ASGKIRWSTPALFAVGSIVTFTMGGLTGVMVGMVPFDWQVHDTYFIVAHLHYVLIGGMVF
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHH
PLFAAFYYWTPMMSRRPLSERWGRWVFALIFLGTHVSFLPMHLTGLMGMPRRVYTYLPGR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEECCCC
DWELTNLISTVGAFMIGAGVLLFILDLARNFRVAVEDNAGNVYGGGTLEWLPTGLYSTRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHCCCCCCCCCC
IPVVRSAYPLWDDPDLPRDVEAGRYFLPGSATGLRETLVTSPIRAEPQYLQRMPGPSVWP
CCHHHCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCHHH
LLAAVFTAGFFMLLTVQAYWPGVVSGVLAVACVLRWLWETDWPMGPASVDIGAGVRVPTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEE
VTGPASHGWWAMVILLVVAGMIFLMACFSYVFLWSRRPDLWLPPPDLVWLAGIVLAYAAA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GGLAWLAARSARTAGRGAGVAALLAGLATILCLAAWAADLGSWRMAGLDPAASGQGATVF
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHH
ALLAFQGVLLSVVVLMAGYLAARTVRGLVAPDRTSTVDLVALFIANAAAQGAIAALLVRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FPGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]