Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 197105020

GI number: 197105020

Start: 1758552

End: 1759496

Strand: Direct

Name: fabD [H]

Synonym: PHZ_c1557

Alternate gene names: 197105020

Gene position: 1758552-1759496 (Clockwise)

Preceding gene: 197105018

Following gene: 197105021

Centisome position: 44.0

GC content: 72.17

Gene sequence:

>945_bases
ATGAGCCTCGCCTTCATCTTCCCCGGCCAGGGCAGCCAGGCCGTCGGCATGGGCGCCGACCTCGCCGACGCCTTCGGCGC
CGCCCGCGAGGTCTTCCAGGAGGTGGACGAGGCCCTGGGCCAGAAGCTCTTCGCCTTGATGCGAGAGGGCCCCGAGGACC
AGCTCACCCTGACCGAGAACGCCCAGCCGGCGCTGATGGCCGTCAGCGTGGCGGTGATGCGGGTGCTGGAGCGGGAGTTC
GGCGTCGGCGTCGAGAGGGCCGCCTTCGTCGCCGGCCACAGCCTGGGCGAATACTCCGCCCTGGCCGCCGCGGGCGCGAT
CAGCCTGTCCGACACCGCCCGGCTGCTGAAGCTGCGCGGCCAGGCGATGCAGCGCGCGGTCCCCGTGGGACAGGGCGCCA
TGGCCTCCCTCATCGGGCCCAAGACGGATCTGGCGCTCGCCGAGGAAGCCGCCAAGGCCGGTTCCGAAGCCGGCGTTTGC
GTGGTCGCCAACGACAACAACCAGGGCAATGTCGTGATCTCCGGCGCCAAGGCCGCGGTCGACCGGGCGATCGAGAAGGC
CAAGGAACTGGGCGCGCGGGCGATCCCGCTGAACGTCTCGGCGCCCTTCCATTGCCCCCTGATGCAGCCGGCCGCCGACG
AGATGGCGCAGGCGCTCACCGCCGCGACGATCGTCACGCCCAAGGCGCCCGTCGTGGCCAACGTCACCGCGCGGCCCACC
AACGACCCCGAGGCCATCCGCCGCCTGCTCGTGGAACAGGTGACCGGTCGCGTGCGCTGGCGCGAGAGCGTCCAGTGGAT
GGCTGGCGAGGGCGGCGTGACCCGCTTCGCCGAGGCCGGGGCGGGGAAGGTGCTCTCCGGCATGGTCAAGCGGATCGCGC
CCGACGCCGAGGCCGTTCCCCTGAACGCCCCCGCCGACCTCGAAGCCTTCGCCAAAACCTTCTAG

Upstream 100 bases:

>100_bases
AAAGGCGGCTCTTGGCGGCCGCGACGTCCTCTGCTTGTCCAGCCTAGCCTAATCCCCTAACCCTCGCGCCTCGGAATCAA
GCAATCAGCGGAGCCCCCGC

Downstream 100 bases:

>100_bases
GAAGCCACCAGATGTTCGACCTCACCGGCAAGACCGCCCTCGTCACCGGCGCCACGGGCGGCATCGGCGCAGAGATCGCC
AGGGCCTTCCACGCCCAGGG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSLAFIFPGQGSQAVGMGADLADAFGAAREVFQEVDEALGQKLFALMREGPEDQLTLTENAQPALMAVSVAVMRVLEREF
GVGVERAAFVAGHSLGEYSALAAAGAISLSDTARLLKLRGQAMQRAVPVGQGAMASLIGPKTDLALAEEAAKAGSEAGVC
VVANDNNQGNVVISGAKAAVDRAIEKAKELGARAIPLNVSAPFHCPLMQPAADEMAQALTAATIVTPKAPVVANVTARPT
NDPEAIRRLLVEQVTGRVRWRESVQWMAGEGGVTRFAEAGAGKVLSGMVKRIAPDAEAVPLNAPADLEAFAKTF

Sequences:

>Translated_314_residues
MSLAFIFPGQGSQAVGMGADLADAFGAAREVFQEVDEALGQKLFALMREGPEDQLTLTENAQPALMAVSVAVMRVLEREF
GVGVERAAFVAGHSLGEYSALAAAGAISLSDTARLLKLRGQAMQRAVPVGQGAMASLIGPKTDLALAEEAAKAGSEAGVC
VVANDNNQGNVVISGAKAAVDRAIEKAKELGARAIPLNVSAPFHCPLMQPAADEMAQALTAATIVTPKAPVVANVTARPT
NDPEAIRRLLVEQVTGRVRWRESVQWMAGEGGVTRFAEAGAGKVLSGMVKRIAPDAEAVPLNAPADLEAFAKTF
>Mature_313_residues
SLAFIFPGQGSQAVGMGADLADAFGAAREVFQEVDEALGQKLFALMREGPEDQLTLTENAQPALMAVSVAVMRVLEREFG
VGVERAAFVAGHSLGEYSALAAAGAISLSDTARLLKLRGQAMQRAVPVGQGAMASLIGPKTDLALAEEAAKAGSEAGVCV
VANDNNQGNVVISGAKAAVDRAIEKAKELGARAIPLNVSAPFHCPLMQPAADEMAQALTAATIVTPKAPVVANVTARPTN
DPEAIRRLLVEQVTGRVRWRESVQWMAGEGGVTRFAEAGAGKVLSGMVKRIAPDAEAVPLNAPADLEAFAKTF

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=298, Percent_Identity=33.5570469798658, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=36.4485981308411, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=44.8051948051948, Blast_Score=231, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=30.6122448979592, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=302, Percent_Identity=28.8079470198675, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI212642053, Length=232, Percent_Identity=29.7413793103448, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665753, Length=310, Percent_Identity=34.1935483870968, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32540; Mature: 32408

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAFIFPGQGSQAVGMGADLADAFGAAREVFQEVDEALGQKLFALMREGPEDQLTLTEN
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
AQPALMAVSVAVMRVLEREFGVGVERAAFVAGHSLGEYSALAAAGAISLSDTARLLKLRG
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
QAMQRAVPVGQGAMASLIGPKTDLALAEEAAKAGSEAGVCVVANDNNQGNVVISGAKAAV
HHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECHHHHH
DRAIEKAKELGARAIPLNVSAPFHCPLMQPAADEMAQALTAATIVTPKAPVVANVTARPT
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCC
NDPEAIRRLLVEQVTGRVRWRESVQWMAGEGGVTRFAEAGAGKVLSGMVKRIAPDAEAVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCC
LNAPADLEAFAKTF
CCCCCCHHHHHHCC
>Mature Secondary Structure 
SLAFIFPGQGSQAVGMGADLADAFGAAREVFQEVDEALGQKLFALMREGPEDQLTLTEN
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
AQPALMAVSVAVMRVLEREFGVGVERAAFVAGHSLGEYSALAAAGAISLSDTARLLKLRG
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
QAMQRAVPVGQGAMASLIGPKTDLALAEEAAKAGSEAGVCVVANDNNQGNVVISGAKAAV
HHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEEECHHHHH
DRAIEKAKELGARAIPLNVSAPFHCPLMQPAADEMAQALTAATIVTPKAPVVANVTARPT
HHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCEEEEEECCCC
NDPEAIRRLLVEQVTGRVRWRESVQWMAGEGGVTRFAEAGAGKVLSGMVKRIAPDAEAVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCCCC
LNAPADLEAFAKTF
CCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]