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The map label for this gene is dnaB [H]

Identifier: 197105006

GI number: 197105006

Start: 1743691

End: 1745181

Strand: Reverse

Name: dnaB [H]

Synonym: PHZ_c1543

Alternate gene names: 197105006

Gene position: 1745181-1743691 (Counterclockwise)

Preceding gene: 197105007

Following gene: 197105004

Centisome position: 43.67

GC content: 69.55

Gene sequence:

>1491_bases
ATGGCGATCGTTCCGGCTCTTGATCTGCGCCCCGTCTCGAACGACGCGGCGATCCCCCACGCTCCAGCCAACATCGAGGC
CGAGCAGGCGCTGCTGGGCGCCCTGCTCTACGACAACGCGGCCTTCGAGCGCCTCGGCGACAACTTGCAGGCGCGCCACT
TCTTCGAGCCCTTCCACCAGCGGCTCTACGCGGCCATCGAGACCCACATCCGCAAGGGCCAGCTCGCGGAGCCGATCCTG
CTCGCCGAGCAGTTCGCCCGCGACCCAGCATTCGAGGAGCTGGGCGGCGTCCGCTACCTGGCCGATCTCGTGGAGCGCGC
CCCGCCCGCGGCCAACGCCCCGGACTATGCACGGGCGATCTACGACCTCGCCCTGCGGCGTGACCTGATCCGGATCGGCG
GCGACATCGCCGCCCAGGCCCAGGCGGGCGACGCCGAGCTCGACGCCCGCGAACAGATCGAACAGGCCGAACAGCAGCTC
TACCAGCTGGCCGAGACCGGCGGCGTCTCCCAGGGCTTCGTGCCGTTCTCCGACGCCCTGCAGGGCGCGCTGGCCATGGC
GGCCGAGGCGCACAGCCGCGACGGCGGGCTCGCCGGCCTCTCCACCGGCCTGATCGACCTCGACCAGAAGATCGGCGGCA
TGCACCCGTCCGACCTGATGATCCTGGCCGCCCGCCCGTCGATGGGGAAGACCTCGCTCGCCTGCAACATCGCCTTCGAC
GTCGCCCGCAACTACGCCTGGGAGCCCCAGCCCGACGGCTCCCGCAAGACGGTCCGCGGCGGCGTGGTGGCCTTCTTCTC
GCTGGAAATGAGCGCCGAGCAGCTCGCCCTGCGCCTGCTCGCCGAGGCCTCGGGCGTCTCGGGCGACCGGCTGCGCAAGG
GCGAGATCGACGCCATGGAGTTCGGCCGCATCCGCGATGCGGCCATGGAGATCCAGGAGGCGCCGCTCTACATCGACGCC
ACCGGCGGCATCACCCTGGCCAAGCTGGTGGCCCGCGCCCGCCGGCTGAAGCGGATGGTCGGCCTCGACCTGATTATCGT
GGACTACCTCCAGCTGGTCACGACCGGCTCCGGCGGCCCCGACAACCGGGTGCAGGAGGTCTCGATGATCACCCAGGGCA
TGAAGGCGCTGGCCAAGGAGCTGAACGTGCCGGTGCTGGCGCTCAGCCAGCTCAGCCGCCAGGTCGAGAACCGCGAGGAC
AAGAAGCCCCAGCTCTCGGACCTGCGCGAATCCGGCTCGATCGAACAGGACGCCGACATGGTGATGTTCGTGTACCGCGA
GGAGTACTACCTCAGCCGCCTGGAGCCCCGCGAAGGCACCGAGGAGCACTTCAAGTGGCAGGAGCAGATGGACCAGGTGC
AGGGGCTGGCCGAGCTCATTATCGGCAAGCAGCGTCACGGCCCCATCGGCACGGTGAAGCTGTCGTTCAACTCCGACACG
ACCAAGTTCGGCAACCTGGCCCGCGACTCGAGCCGCTACGAGCCCCACTAG

Upstream 100 bases:

>100_bases
CAAGCTTCATCCACAGGTTCAGAAAAGTTCTGGGGAGAATTGGTCGCAGCGACATGTGGCGCCCGTGATCGGACGGCCCT
GGACCGCTATCGATTGAGGC

Downstream 100 bases:

>100_bases
GGCGGCGGCCGCGCCCCTACGAGAACTGCAGCGGCCCGCCCAGCTCGGCCGCCCGGGCGATCGCCAGGGCCCTGAGCGCG
CCCACCGCGAGCGCGGCCAG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MAIVPALDLRPVSNDAAIPHAPANIEAEQALLGALLYDNAAFERLGDNLQARHFFEPFHQRLYAAIETHIRKGQLAEPIL
LAEQFARDPAFEELGGVRYLADLVERAPPAANAPDYARAIYDLALRRDLIRIGGDIAAQAQAGDAELDAREQIEQAEQQL
YQLAETGGVSQGFVPFSDALQGALAMAAEAHSRDGGLAGLSTGLIDLDQKIGGMHPSDLMILAARPSMGKTSLACNIAFD
VARNYAWEPQPDGSRKTVRGGVVAFFSLEMSAEQLALRLLAEASGVSGDRLRKGEIDAMEFGRIRDAAMEIQEAPLYIDA
TGGITLAKLVARARRLKRMVGLDLIIVDYLQLVTTGSGGPDNRVQEVSMITQGMKALAKELNVPVLALSQLSRQVENRED
KKPQLSDLRESGSIEQDADMVMFVYREEYYLSRLEPREGTEEHFKWQEQMDQVQGLAELIIGKQRHGPIGTVKLSFNSDT
TKFGNLARDSSRYEPH

Sequences:

>Translated_496_residues
MAIVPALDLRPVSNDAAIPHAPANIEAEQALLGALLYDNAAFERLGDNLQARHFFEPFHQRLYAAIETHIRKGQLAEPIL
LAEQFARDPAFEELGGVRYLADLVERAPPAANAPDYARAIYDLALRRDLIRIGGDIAAQAQAGDAELDAREQIEQAEQQL
YQLAETGGVSQGFVPFSDALQGALAMAAEAHSRDGGLAGLSTGLIDLDQKIGGMHPSDLMILAARPSMGKTSLACNIAFD
VARNYAWEPQPDGSRKTVRGGVVAFFSLEMSAEQLALRLLAEASGVSGDRLRKGEIDAMEFGRIRDAAMEIQEAPLYIDA
TGGITLAKLVARARRLKRMVGLDLIIVDYLQLVTTGSGGPDNRVQEVSMITQGMKALAKELNVPVLALSQLSRQVENRED
KKPQLSDLRESGSIEQDADMVMFVYREEYYLSRLEPREGTEEHFKWQEQMDQVQGLAELIIGKQRHGPIGTVKLSFNSDT
TKFGNLARDSSRYEPH
>Mature_495_residues
AIVPALDLRPVSNDAAIPHAPANIEAEQALLGALLYDNAAFERLGDNLQARHFFEPFHQRLYAAIETHIRKGQLAEPILL
AEQFARDPAFEELGGVRYLADLVERAPPAANAPDYARAIYDLALRRDLIRIGGDIAAQAQAGDAELDAREQIEQAEQQLY
QLAETGGVSQGFVPFSDALQGALAMAAEAHSRDGGLAGLSTGLIDLDQKIGGMHPSDLMILAARPSMGKTSLACNIAFDV
ARNYAWEPQPDGSRKTVRGGVVAFFSLEMSAEQLALRLLAEASGVSGDRLRKGEIDAMEFGRIRDAAMEIQEAPLYIDAT
GGITLAKLVARARRLKRMVGLDLIIVDYLQLVTTGSGGPDNRVQEVSMITQGMKALAKELNVPVLALSQLSRQVENREDK
KPQLSDLRESGSIEQDADMVMFVYREEYYLSRLEPREGTEEHFKWQEQMDQVQGLAELIIGKQRHGPIGTVKLSFNSDTT
KFGNLARDSSRYEPH

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=476, Percent_Identity=37.3949579831933, Blast_Score=292, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 54376; Mature: 54245

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVPALDLRPVSNDAAIPHAPANIEAEQALLGALLYDNAAFERLGDNLQARHFFEPFHQ
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
RLYAAIETHIRKGQLAEPILLAEQFARDPAFEELGGVRYLADLVERAPPAANAPDYARAI
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCHHHHHHHHHHHCCCCCCCCHHHHHH
YDLALRRDLIRIGGDIAAQAQAGDAELDAREQIEQAEQQLYQLAETGGVSQGFVPFSDAL
HHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QGALAMAAEAHSRDGGLAGLSTGLIDLDQKIGGMHPSDLMILAARPSMGKTSLACNIAFD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEHHH
VARNYAWEPQPDGSRKTVRGGVVAFFSLEMSAEQLALRLLAEASGVSGDRLRKGEIDAME
HHHCCCCCCCCCCCCCHHHCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FGRIRDAAMEIQEAPLYIDATGGITLAKLVARARRLKRMVGLDLIIVDYLQLVTTGSGGP
HHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
DNRVQEVSMITQGMKALAKELNVPVLALSQLSRQVENREDKKPQLSDLRESGSIEQDADM
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCE
VMFVYREEYYLSRLEPREGTEEHFKWQEQMDQVQGLAELIIGKQRHGPIGTVKLSFNSDT
EEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
TKFGNLARDSSRYEPH
CHHCCHHCCCCCCCCC
>Mature Secondary Structure 
AIVPALDLRPVSNDAAIPHAPANIEAEQALLGALLYDNAAFERLGDNLQARHFFEPFHQ
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
RLYAAIETHIRKGQLAEPILLAEQFARDPAFEELGGVRYLADLVERAPPAANAPDYARAI
HHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHCHHHHHHHHHHHCCCCCCCCHHHHHH
YDLALRRDLIRIGGDIAAQAQAGDAELDAREQIEQAEQQLYQLAETGGVSQGFVPFSDAL
HHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
QGALAMAAEAHSRDGGLAGLSTGLIDLDQKIGGMHPSDLMILAARPSMGKTSLACNIAFD
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEHHH
VARNYAWEPQPDGSRKTVRGGVVAFFSLEMSAEQLALRLLAEASGVSGDRLRKGEIDAME
HHHCCCCCCCCCCCCCHHHCCEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
FGRIRDAAMEIQEAPLYIDATGGITLAKLVARARRLKRMVGLDLIIVDYLQLVTTGSGGP
HHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCC
DNRVQEVSMITQGMKALAKELNVPVLALSQLSRQVENREDKKPQLSDLRESGSIEQDADM
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCE
VMFVYREEYYLSRLEPREGTEEHFKWQEQMDQVQGLAELIIGKQRHGPIGTVKLSFNSDT
EEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCC
TKFGNLARDSSRYEPH
CHHCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA